patient education : 16252--Cemiplimab (Libtayo®)

Cemiplimab (Libtayo®)

Treatment name

Type of Treatment

How long will it take?

Cemiplimab-rwlc (Libtayo®)

Immunotherapy

About 2 hours

Given once every 21 days

How is cemiplimab given?

Cemiplimab is given through a vein by intravenous infusion (IV) over 30 minutes.

Immune related side effects

Skin rash

You may get: a red rash, bumpy rash, dry and itchy skin or skin peeling or blisters.

Moisturize your skin daily and avoid scratching.

Notify clinic if you have severe pain or itching from rash

Bowel and stomach inflammation

Diarrhea, blood in stool, bloating or stomach cramping can occur.

May use loperamide as directed on the package for mild diarrhea.

Notify clinic if you have 4 or more episodes of diarrhea in 24 hours or blood in your stool.

Lung inflammation

You may develop inflammation of your lungs from cemiplimab.

Notify clinic if you have shortness of breath, difficulty breathing, faster heartbeat, chest pain, or new or worsening cough.

Muscle and joint problems

You may get: muscle or joint stiffness or pain, muscle weakness, joint swelling.

Notify clinic if you are unable to complete your normal daily activities due to these problems.

Thyroid changes

Thyroid changes are common with cemiplimab, specifically underactive thyroid. You may notice: fatigue or low energy levels, depression, slow heart rate, weight gain, intolerance to cold, dry skin, hair loss, constipation.

Less common but severe side effects

Notify clinic if you have any of the bolded symptoms

• Heart damage

Chest pain, shortness of breath, abnormal heart beat)

• Liver damage

Dark urine, yellow skin or eyes, unexplained bruising or bleeding or severe stomach pain

• Hormone changes or central nervous system changes

Bad headaches, confusion, weakness, dizziness, fainting, numbness in hands or feet

• Eye problems

Any change in vision