Events Calendar - School of Medicine

 

Type:
All
Department:
School of Medicine [x]
Audience:
All
CME:
All
  • Sunday
  • Monday
  • Tuesday
  • Wednesday
  • Thursday
  • Friday
  • Saturday
  • Date
  • Time
  • Event
  • Department

Thu25

09:30 AM

day:
Thursday
date:
04/25/2019
time:
9:30 AM - 10:30 AM
event:
"Neural Circuits in Sleep and Epilepsy" by Nigel Pedersen
area:
location:
PINN 1-17
type:
Seminar
department:
Pharmacology
services:
audience:
Faculty Students
details:
Hosted by Steve Abbott, Nigel Pederson, PhD, is an Assistant Professor of Neurology, Emory University, Atlanta, GA.

In the Pedersen Epilepsy and Systems Neuroscience Laboratory, we study the systems neuroscience of wakefulness and epilepsy in humans and animal models. There are two main streams of research. The first centers on the neurobiological basis of consciousness and the underlying wake-sustaining mechanisms upon which it depends (1-6); another group of projects examines brain networks in epileptic seizures, including the modulatory effects of sleep-wake circuits and networks through which seizures propagate.

We study large-scale brain circuits underlying wakefulness and sleep. Using a variety of genetically encoded technologies in mice, we have recently described a new component of the brain circuit that maintains wakefulness, the supramammillary hypothalamus (3). This region exerts control over both the hippocampal network (important for certain kinds of memory formation) as well as the wake network and cerebral cortex. A unique and interesting feature of this neuronal group is the presence of a subpopulation of neurons that we described to release both inhibitory GABA and excitatory glutamate on to a key population of hippocampal neurons - dentate granule cells (3). These neurons are sparsely firing neurons that control which activity enters the classical hippocampal tri-synaptic circuit. The supramammillary region, comprising three major neuronal populations (3), is thus able to control wakefulness and influence information flow into the hippocampus. Studies continue to understand the role of these circuits on attention, wakefulness and the role of this region in setting hippocampal excitability in epilepsy. A specific ongoing experiment involves disruption of GABA release by supramammillary neurons and examining spontaneous seizures and seizure threshold, using Cre-lox techniques. We are also examining the anatomical connectivity and spontaneous activity of identified supramammillary neuronal subpopulations using unit recording and, later, fiber photometry.
URL:
http://epilepsylaboratory.org/
isCME:
No
speakers:
Nigel P. Pedersen, Phd, Assistant Professor, Neurology, Emory University, Atlanta, GA
registration:
No registration is necessary
contact:
Antoinette Reid Pharmacology 434-924-1919 adw2n@Virginia.EDU
Attachments:
SeminarNotice_Nigel Pedersen.pdf


Find Events by Date:

< April 2019 >
S M T W T F S
1 2 3 4 5 6
7 8 9 10 11 12 13
14 15 16 17 18 19 20
21 22 23 24 25 26 27
28 29 30

Refine View By:

Department:
Administration Administrator Development Admissions Anesthesiology Animal Care and Use Asthma, Allergy & Immunology Basic Science Departments Biochemistry, Molecular Biology and Genetics Biodefense Training Biology Biomedical Sciences Graduate Program Biomolecular Research Biophysics Graduate Program Biotechnology Training Program Cancer Center Cancer Center Research Program Events Cancer Center Seminar Series Cardiovascular Medicine Cardiovascular Research Center Carter Immunology Center Celebration Committee Cell Biology Cell and Developmental Biology Graduate Program Cell and Molecular Biology Graduate Program Center for Appreciative Practice Center for Cell Signaling Center for Comparative Medicine Center for Global Health Center for Health Humanities and Ethics Center for Improving Minority Health Center for Membrane and Cell Physiology Center for Public Health Genomics Center for Research in Reproduction Child Health Research Center Clinical Departments Clinical Trials Office Community Service Continuing Medical Education Department of Medicine Dermatology Diabetes Center Education Emergency Medicine Endocrinology & Metabolism Faculty Development Family Medicine Gastroenterology & Hepatology General Clinical Research Center General Medicine, Geriatrics & Palliative Care Go Girls Graduate Biosciences Society Graduate Programs Office Hematology & Oncology Infectious Diseases Infectious Diseases & International Health Infectious Diseases Training Program Journal Club LCME M.D./Ph.D. Program MSTP Medical Education Microbiology, Immunology and infectious Diseases Graduate Program Microbiology, Immunology, and Cancer Biology Molecular Cell and Developmental Biology Molecular Medicine Graduate Program Molecular Physiology & Biophysics Nephrology; Center for Immunity, Inflammation & Regenerative Medicine Neurology Neuroscience Neuroscience Graduate Program OB / Gyn Office of Research Core Administration Office of the Dean Ophthalmology Orthopaedic Surgery Otolaryngology Pathology Patient Care Pediatrics Pediatrics: GME Pharmacology Physical Medicine and Rehabilitation Psychiatry and Neurobehavioral Sciences Public Health Sciences Pulmonary & Critical Care Radiation Oncology Radiology Radiology and Medical Imaging Research Research-Office Rheumatology School of Medicine Stress Reduction Structural, Computational Biology Surgery Urology Women in Medicine Network

Type of Event:
Announcements Blood Drive Class Concert Conference Continuing Medical Education Education Offerings Exhibit Faculty Meeting FEAP Festival Forum Fundraiser Grand Rounds Immunization Interfaith Services Lecture Medical Center Hour Miscellaneous Open House Orientation Race/Walk Reception Recruiting Event Screening Seminar Support Group Symposium

Audience:
Employees Everyone Faculty Nurses Patients Students

CME:
No Yes, credit available Yes, no credit


Calendars: