Hosted by Microbiology and Co-hosted by Pharmacology (Adishesh Narahari, Michael Schappe and Pharm Students), Sergio Grinstein, PhD, is a Professor of Biochemistry, University of Toronto, Toronto, ON

RESEARCH DESCRIPTION

Membrane Biology, Ion Transport, and the Innate Immune Response

Dr. Grinstein’s group is interested in several aspects of membrane biology and signal transduction. Part of his group studies ion transport mechanisms and regulation, with particular interest in the regulation of the intracellular pH. Another sub-group studies the molecular basis of the innate immune response, mostly in macrophages. The receptors, signals and effectors that mediate phagocytosis are topics of interest, as is the interaction of pathogens with host cells.