Women's Health

 

Hysterectomy Leads To Improved Symptoms And Satisfaction

Studies Compare Medication Therapy To Surgical Procedure

Two new studies on hysterectomy and quality of life conclude that, while there is a place for surgery in easing abnormal bleeding, making this choice usually depends on the individual woman.Picture of a woman, smiling

The reports, presented in the Journal of the American Medical Association (JAMA), show that about 50 percent of the women taking medication to control bleeding eventually had a hysterectomy because of dissatisfaction with the more conservative therapy.

Hysterectomy, which is the surgical removal of the uterus, is the most common major surgical procedure performed in the US for non-obstetric reasons, according to one of the study reports.

In 2000, about 633,000 hysterectomies were performed. Women in the US have an estimated 25 percent risk of having their uterus removed.

The authors note that usually a hysterectomy is elective and performed before menopause for abnormal uterine bleeding and other non-life-threatening reasons.

"It's kind of a judgment call," says Dr. James R. Scott, co-author of an editorial accompanying the two studies in JAMA. "It depends a lot on the woman. A lot of women don't want surgery. Others say they're just tired and want to get it done."

Points to Consider

"When women 40 and over are considering hysterectomy, the question usually comes up about whether to remove one or both ovaries at the time of surgery. Ovaries can be removed whether the surgery is done vaginally or thru an abdominal incision," according to Dr. JoAnn V. Pinkerton, director of the UVa Women's Midlife Center and national HRT expert. "Usually for women under 45, I recommend saving at least one ovary to avoid going through early menopause. Sometimes, both ovaries are removed because of the medical condition involved, such as severe endometriosis where the ovaries could stimulate further growth of endometriosis. For women over 45, it is a decision best made between an informed women and her surgeon."

Pinkerton continues, "If both ovaries are removed, this is called surgical menopause. To prevent menopausal symptoms, estrogen, often in patch form, is placed on the body in the recovery room. Estrogen therapy is continued after discharge with a slow decrease of the dose over time."

Research Delves Into Satisfaction, Outcomes

There has been a great deal of debate about whether this type of surgery is performed too often. It is, after all, major surgery. It involves significant recovery time, discomfort, and, like all surgery, a small risk of death.

The studies may provide new information that will lessen the negative reputation that is sometimes associated with hysterectomy.

"Hysterectomy has had a bad name, and it probably isn't as bad as has been implied - by some, anyway," says Dr. Scott, who is also editor of Obstetrics & Gynecology.

The first study randomly assigned 63 premenopausal women with abnormal uterine bleeding to receive either a hysterectomy or "expanded medical treatment," including hormone therapy.

The women, all of whom had tried and stopped the hormone therapy medroxyprogesterone, were followed for about two years to assess their mental health and quality of life.

After six months, women in the hysterectomy group showed greater improvements in overall mental health than women in the medication treatment group.

They also had greater improvement in symptom resolution, symptom satisfaction, interference with sex, sexual desire, health desire, sleep problems, overall health, and satisfaction with health.

Interestingly, at the end of two years, more than half (53 percent) of the women in the medication group had requested and received a hysterectomy and reported improvements.

Women who continued with the medications also reported improvements, indicating this course of action may eventually lead to improved quality of life.

In sum, though, hysterectomy seemed to come out ahead.

Women Must Weigh Information, Choices

Dr. Miriam Kuppermann, author of the first study, says, "Women who have abnormal bleeding that have tried medicine and hasn't worked well, [then] hysterectomy is a very good option for them - not that every woman should have a hysterectomy." Kuppermann is an associate professor of obstetrics, gynecology, and reproductive science at the University of California San Francisco.

"For women who have not been adequately treated by medicine, hysterectomy is a worthwhile option to consider," she says.

On the other hand, if a woman really does not want the operation, she can expect to get some benefit from medications, Dr. Kuppermann adds.

Dr. Kuppermann points out that the study was small and reflected the difficulty of finding women to participate who were willing to be placed in either group. She says it is "unclear" whether these women represent the entire population of women choosing between medication and surgery.

The second study, taking place in Finland, compared levonorgestrel-releasing intrauterine system (LNG-IUS) with hysterectomy in women with menorrhagia, the medical term for unusually heavy menstrual bleeding.

Levonorgestrel is a hormone. In Finland, the LNG-IUS is approved for contraception and treatment of menorrhagia while, in the US, it is approved only for contraception. Leiras Co. (now Schering) provided the LNG-IUS free of charge.

Here, the researchers randomly assigned 236 women at five university hospitals in Finland to be treated with the LNG-IUS or hysterectomy. All women were monitored for five years.

The two groups were similar in terms of health-related quality of life and psychosocial well-being. As with the first study, however, a sizable proportion (42 percent) of the women in the nonsurgical group eventually opted for a hysterectomy.

Dr. Kuppermann says, "I can speak more to the [San Francisco] Bay Area. Here, there really has been an emphasis on trying every last thing before resorting to hysterectomy. This [study] may have an impact. It may introduce hysterectomy as an option earlier on.

"There are a lot of choices," Dr. Kuppermann says. "Hysterectomy is a viable option. There has been so much press about overuse, but realize that for that situation, it is a very effective option."

Always consult your physician for more information.

May 2004

Hysterectomy Leads To Improved Symptoms And Satisfaction

Research Delves Into Satisfaction, Outcomes

Women Must Weigh Information, Choices

Why Is Hysterectomy Performed?

Types of Hysterectomy Procedures

Online Resources


Why Is Hysterectomy Performed?

According to the American College of Surgeons, hysterectomy may be performed to treat a variety of gynecological (female reproductive
system) problems.

It is an elective procedure 90 percent of the time. Today most hysterectomies are done to treat
benign (non-cancerous) fibroid tumors of the uterus. While not life-threatening, these growths cause pelvic pain, excessive bleeding, or pain during sexual intercourse.

Fibroid tumors are common
and usually do not require surgery. Other forms of treatment which preserve the uterus and
childbearing capacity are also available.

A woman should discuss these options with her surgeon.

Endometriosis is a condition in which the tissue lining the uterus becomes displaced and grows in
other parts of the abdomen, where it can cause pain. Endometriosis is the second most common
reason for a woman to have a hysterectomy.

However, the practice of treating endometriosis by performing hysterectomy has been declining
in the last decade because other treatments have evolved. The American College of Surgeons recommends that a woman discuss other options with her surgeon first to see if another treatment for endometriosis may be effective for her.

Prolapse of the uterus is another reason why some women decide to undergo a hysterectomy. In this condition, the uterus descends or sags into the vagina due to stretching of the ligaments and
fibrous tissue that usually hold it in place.

Women with cancer of the uterus or cancer of the cervix require special types of treatment which
may include a simple or radical hysterectomy. These women should seek the counsel of a gynecologic oncologist, states the surgeon group.

Types of Hysterectomy Procedures

The American College of Surgeons explains that a woman may hear different names used to refer
to this type of operation. That is because there are different types of hysterectomies.

A total hysterectomy(panhysterectomy) applies only
to the removal of the uterus and cervix.

When the ovaries and fallopian tubes on both sides of the
uterus are also removed, the procedure is called a hysterectomy and bilateral salpingo-oophorectomy.  

Hormonal Considerations

According to Dr. JoAnn V. Pinkerton, director of the UVa Women's Midlife Center and national HRT expert, "In addition to estrogen therapy, testosterone is sometimes needed and can be given in an oral form combined with estrogen (Estratest). Testosterone will soon also be available in patch form. If estrogen is not given, menopausal symptoms such as significant hot flashes, night sweats, mood swings, or insomnia may develop. Bone loss also occurs which could lead to osteoporosis. The younger the age at which the ovaries are removed, the more severe the symptoms and bone loss may be. In natural menopause, there is a prolonged period of waxing and waning of hormones, instead of the abrupt withdrawal which occurs when the ovaries are both removed surgically."

A radical hysterectomy is a much more extensive procedure and is only performed in special situations such as cancer of the uterus or cervix. It includes removal of the uterus, cervix, and surrounding tissue, the upper vagina, and usually the pelvic lymph nodes. A surgeon with special training in gynecologic oncology performs this type of procedure.

According to Pinkerton, "Women who have had their uteruses (wombs) removed do not need progesterone which is given along with estrogen to protect against cancer of the uterus. There may be a small increase in breast cancer with estrogen only. An increased risk of breast cancer was shown in the Million Women Study in Britain but not in the WHI study. How long to continue estrogen is a decision best made between the women and her health care provider and will depend on symptoms, personal risk of breast cancer and osteoporosis and length of use, and amount needed to control symptoms. Lower doses are being shown effective at improving symptoms with theoretical improved safety."

Always consult your physician for more information.


Online Resources

(Our Organization is not responsible for the content of Internet sites.) 

UVa Women's MIdlife Center

Centers for Disease Control and Prevention (CDC)

HealthierUS.Gov

National Institutes of Health (NIH)

National Library of Medicine

National Women's Health Information Center

Office of Research on Women's Health