Laboratory Medicine Updates - 10/30/2001
University of Virginia Health System
“Quality You Expect, Service You Deserve”
LABORATORY MEDICINE UPDATE
October 30, 2001
REFERENCE INTERVAL CHANGE FOR PTT-LA
Effective November 6, 2001, the Special Coagulation Laboratory will change the reference interval for the PTT-LA test, part of the screening panel for the presence of Lupus Anticoagulant. The new reference interval will be 30.8 to 53.6 s. This change reflects a broader population study and increased familiarity with this test.
CHANGES IN Hep-PT OFFERING
The Special Coagulation Laboratory has determined that heparin removal is not necessary in samples with a PTT value of less than 200 s due to a change in the formulation of the PT reagent. Therefore, if a Hep-PT is requested but the PTT is less than 200 s, treatment with an additional heparin removal agent will not be performed.
ENHANCED PRENATAL SCREENING – QUAD SCREENING
The Davis Laboratory announces the addition of a fourth prenatal marker for assessing risk of Downs in fetal development. The fourth marker, Dimeric Inhibin A, has been shown to provide increased sensitivity in risk assessment, without increasing the false-positive rate of this screening. Four-marker screening (Quad screening) yields a detection rate of approximately 76% according to published studies.
Addition of this test to the current Triple Profile does not change sample requirements, handling, or patient preparation. The charge will be $25.00 more than the current triple screening. New test request forms are being distributed to facilitate ordering of this fourth marker. In the interim, clinics may write INHIBIN on the test request form or request QUAD SCREENING. Triple screening (hCG, AFP, uE3) will continue to be offered.
Questions regarding the clinical or technical details involved in this expanded profile should be addressed to Laura Niewiadomski at (434) 924-2664. To discuss details regarding billing and account discounts, please contact Rick Ross at (434) 243-2995.
SURGICAL PATHOLOGY REQUISTIONS
Surgical Pathology requisitions are now available online at:
URINE ALBUMIN/CREATININE RATIO
To assist in the diagnosis and monitoring of renal function in patients with diabetes, an Albumin/Creatinine Ratio is recommended by the American Diabetes Association (Diabetes Care, volume 22, supplement 1, January 1999).
Requested Sample: SPOT URINE
Test Code: UACR
The test MICROALBUMIN should only be ordered for 24-hour urine collections.