Children, women and men and adolescents who are all less than 30 with Wilm' tumor wanted for clinical study.
13671
Treatment for Very Low and Standard Risk Favorable Histology Wilms Tumor
Pediatrics
Dunsmore Kimberly, P
UVa Health System, Department of Pediatrics seeks: children, adolescents, women and men with newly diagnosed favorable histology Wilms tumor who are less than 30 years of age at the time of diagnosis for research study. The main purpose of the study is to provide a high degree of overall survival while minimizing toxicity. The main goals of this study are to find out (a) if children less than 2 years old with a small Stage I Wilms tumor can be safely treated with surgery alone followed by careful observation, (b) if some patients with a higher risk of having their tumor return will benefit from the addition of doxorubicin to the current standard treatment regimen, and (c) if there are things about the tumor cells that might tell us why standard treatment does not get rid of the tumor for Stage III Wilms tumor patients. The study involves blood draws, physical exams, urinalysis, test for kidney function, test for heart function (echocardiogram) for some patients, chest X-ray, ultrasound, CT scans and possibly MRI scans. Depending on the treatment plan you receive, the study also involves taking FDA approved chemotherapy agents. The length of the visits will be shorter than or comparable to the length of the visits you would receive for standard of care treatment. Subjects receiving chemotherapy will receive treatment for about 26 weeks (0.5 years). Data will be collected on all patients for about 5 years after the study closes to new patient enrollment. You and/or your insurance will be billed for all study related medication, tests, treatment, and procedures. No compensation is provided for this study. Contact Information: For more information please contact: " Candace Hudspeth, CCRC " Tel: 434-982-1091 Email: ckh3k@virginia.edu " IRB-HSR # 13671 (COG AREN0532) Principal Investigator: Kimberly P. Dunsmore, MD
Hematology/Oncology
Pediatric Cancers: Wilm's Tumor and Kidney Cancer
Pediatrics
Cancer (Oncology)
Ill
No Compensation
Candy Hudspeth
ckh3k@virginia.edu
4349821091
