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Frederick  H.  Epstein
Degree(s): Ph.D.
Graduate School: University of Virginia
Primary Appointment: Associate Professor of Radiology, Radiology Research
Research Interests:
Cardiovascular Magnetic Resonance Imaging; Coronary Heart Disease; Myocardial Function; Myocardial Perfusion

Email Address: fhe6b@virginia.edu


Biomedical Sciences Graduate Program(s)
  • Biomedical Engineering

  • Research Description

    The general goal of my lab is to develop MRI techniques for assessing the structure, function, and perfusion of the cardiovascular system, particularly in the setting of coronary heart disease. Recent projects have included developing echo-planar MRI methods for imaging myocardial perfusion throughout the entire heart and developing displacement-encoded MRI for high-resolution measurements of intramyocardial motion. We have access to state-of-the-art whole body 1.5T scanners for human imaging studies and to a high-field 4.7T MRI scanner for imaging small animals, particularly mice. Through collaborations with cardiologists and molecular biologists, our novel MRI methods are applied to studies involving both clinical cardiology and basic cardiovascular science.


    Selected Publications
  • Epstein FH, London JF, Peters DC, Goncalves L, Agyeman K, Taylor J, Balaban RS, Arai AE. Multi-slice first-pass cardiac perfusion MRI: validation in a model of myocardial infarction. Magn Reson Med 2002: 47; 482-491.
  • Epstein FH, Yang Z, Gilson WD, Berr SS, Kramer CM, French BA. MR tagging early after myocardial infarction in mice demonstrates contractile dysfunction in adjacent and remote regions. Magn Reson Med 2002: 8(2); 399-403.
  • Zequan Yang, Christina M. Bove, Brent A. French, Frederick H. Epstein, Stuart S. Berr, Joseph M. DiMaria, Jennifer J. Gibson, Robert M. Carey, Christopher M. Kramer. Angiotensin II Type 2 Receptor Overexpression Preserves Left Ventricular Function After Myocardial Infarction. Circulation 106:106-111, 2002.
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      Office Address: PO Box 801339, Snyder Building, 480 Ray C Hunt Drive, 
      Office Phone: +1 434-982-0563

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