Marie-Louise Hammarskjöld
Publications (selected from >60):
Bray, M., Prasad, S. Dubay, J.W., Hunter, E. Jeang,K.T., Rekosh, D. and Hammarskjold-M-L. (1994) A small element from the Mason-Pfizer monkey virus genome makes human immunodeficiency virus type 1 expression and replication Rev-independent. Proc. Natl. Acad.Sci.(USA) 91: 1256-1260.
Hammarskjold ML, Li H, Rekosh D, Prasad S. (1994) Human immunodeficiency virus env expression becomes Rev-independent if the env region is not defined as an intron. J Virol. 1994 68 951-958.
Ciccarelli, R.B., Winter, L.A., Lorenz, R., Harris, A.L., Crawford, A.C., Bailey, T.R., Singh, B., Hammarskjöld, M. L., Rekosh, D. and Hughes, J.V. (1994) Inhibition of the cellular rev response and HIV-1 replication by 8-alkyl-2-(4-pyridyl)pyrido[2,3-d]pyrimidin-5(8H)-ones. Antiviral Chem and Chemo, 5,169-175.
Mak, J., Jiang, M., Wainberg M.A.,Hammarskjöld, M.-L., Rekosh, D. and Kleiman, L.(1994) Role of Pr160 in mediating the selective incorporation of tRNAlys into HIV-1 particles J. Virol. 68: 2065-2072.
Dundr, M., Leno, G. H., Hammarskjöld, M.-L., Rekosh, D., Helga-Maria, C. and Olson, M. O. J. (1995) The roles of nucleolar structure and function in the sub cellular location of the HIV-1 Rev protein. J. of Cell Sci. 108: 2811-2823
Berkowitz, R. D., Hammarskjöld, M.-L., Helga-Maria, C., Rekosh, D. and Goff, S. P. (1995) 5' Regions of HIV-1 RNAs Are Not Sufficient for Encapsidation: Implications for the HIV-1 Packaging Signal. Virology 212: 718-723.
Srinivasakumar, N., Hammarskjöld, M.-L., and Rekosh, D.M. (1995) Characterization of Deletion Mutations in the Capsid Region of Human Immunodeficiency Virus Type 1 That Affect Particle Formation and Gag-Pol Precursor Incorporation. J. Virol. 69: 6106-6114.
Orsini, M.J., Thakur, A.N., Andrews, W.W., Hammarskjöld, M.-L. and Rekosh, D.M. (1995) Expression and purification of the HIV-1 Rev protein and its use in the generation of monoclonal antibodies. AIDS Research and Human Retroviruses, 11: 945-953
Dundr, M. Leno, M., Lewis, N., Rekosh, D., Hammarskjöld, M.L. and Olson, M. O.J. (1996) Location of the HIV1 rev protein during mitosis: Inactivation of the nuclear export signal alters the pathway for postmitotic reentry, J. of Cell Sci., 109:2239-2251
Hammarskjold ML. (1997) Regulation of retroviral RNA export. Semin Cell Dev Biol. Feb;8(1):83-90.
Srinivasakumar, N., Chazal, N., Helga-Maria, C., Prasad, S., Hammmarskjöld, M.-L., and Rekosh, D (1997). The effect of viral regulatory protein expression on gene delivery using human immunodeficiency virus type 1 vectors produced in stable packaging cell lines J. Virol 71:5841-5848.
Pasquinelli, A. E., Ernst, R. K., Lund,E., Grimm, C., Zapp, M. L., Rekosh,D., Hammarskjöld, M.-L. and Dahlberg, J.E. (1997) The Constitutive Transport Element (CTE) of Mason-Pfizer Monkey Virus (MPMV) Accesses a Cellular mRNA Export Pathway, EMBO J. 16: 7500-7510Hammarskjöld, M-L (1997) Regulation of retroviral RNA transport ,Sem. Cell. Develop. Biol., 8:83-90
Ernst, R.K., Bray, M., Rekosh, D. and Hammarskjöld, M.-L. (1997), Secondary structure and mutational analysis of the Mason-Pfizer monkey virus RNA constitutive transport element. RNA, 3: 210-222
Ernst, R.K., Bray, M., Rekosh, D. and Hammarskjöld, M.-L. (1997) A structured retroviral RNA element that mediates nucleocytoplasmic export of intron-containing RNA Mol. Cell Biol 17: 135-144
Hamm, T. E., Rekosh, D. and Hammarskjöld, M-L. (1999) Selection and Characterization of HIV-1 Mutants that are Resistant to Inhibition by the Transdominant Negative RevM10 Protein. J. Virol., 73:5741-5747
Helga-Maria, C., Hammarskjöld, M-L. and Rekosh, D. (1999) An Intact TAR Element and Cytoplasmic Localization Are Necessary for Efficient Packaging of HIV Type 1 Genomic RNA. J. Virol. 73:4127-4135.
Bishop GG, Wiegman P, McNamara C, Din S, Sanders J, Hesselbacher S, Feldman M, McPherson JA, Humphries JE, Hammarskjold ML, Gimple LW, Ragosta M, Powers ER, Dickek D, Owens GK, Sarembock IJ. (1999) Local adenovirus-mediated delivery of hirudin in a rabbit arterial injury model. J Vasc Res. 1999 Sep-Oct;36(5):343-52
Chien ML, Hammarskjold ML. (2000) Epstein-barr virus latent membrane protein (LMP1) induces specific NFkappaB complexes in human T-lymphoid cells. Virus Res. 67 17-30.
Lévesque,L. Guzik, G, Guan, T., Coyle,J. Black, B.E., Rekosh,D. Hammarskjöld, M.-L. and Paschal, B.M. (2001) RNA export mediated by tap Involves NXT1-dependent interactions with the nuclear pore complex
J. Biol. Chem. 276 44953-44962. Hammarskjold ML.(2001) Constitutive transport element-mediated nuclear export. Cur Top Micro.Im.259:77-93 Chazal N, Singer G, Aiken C, Hammarskjold ML, and Rekosh D.(2001) Human Immunodeficiency Virus Type 1
Particles Pseudotyped with Envelope Proteins That Fuse at Low pH No Longer Require Nef for Optimal
Infectivity. J Virol.75 4014-4018.
Guzik, B.W., Levesque, L.,Prasad, S, .Bor, Y.-C., Black, B.E., Paschal, B., Rekosh, D. and Hammarskjöld,M.L.,(2001) NXT1/p15 is a Crucial Cellular Cofactor in TAP Dependent Export of Intron-Containing RNA in Mammalian Cells, Mol Cell Biol.21:2545-2554
Walk,S.F., Alexander, M., Hammarskjold,M.-L., Rekosh, D.M.and Ravichandran, K.S. (2001) Design and Use of an Inducibly-Activated HIV-1 Nef to Study Immune Modulation, J. Virol., J Virol. 75:834-843 Matsumura ME, Li F, Berthoux L, Wei B, Lobe DR, Jeon C, Hammarskjold ML, McNamara CA.(2001) Vascular injury induces posttranscriptional regulation of the Id3 gene: cloning of a novel Id3 isoform expressed during vascular lesion formation in rat and human atherosclerosis. Arterioscl Thromb Vasc Biol. 21:752-8.
Mierisch CM, Wilson HA, Turner MA, Milbrandt TA, Berthoux L, Hammarskjold ML, Rekosh D, Balian G, Diduch DR. (2003) Chondrocyte transplantation into articular cartilage defects with use of calcium alginate: the fate of the cells.J Bone Joint Surg Am. 85-A(9):1757-1767.
Jin L, Guzik BW, Bor YC, Rekosh D, Hammarskjold ML. (2003) Tap and NXT promote translation of unspliced mRNA.Genes Dev 17 3075-86.
Coyle JH, Guzik BW, Bor YC, Jin L, Eisner-Smerage L, Taylor SJ, Rekosh D, Hammarskjold ML. (2003) Sam68 enhances the cytoplasmic utilization of intron-containing RNA and is functionally regulated by the nuclear kinase Sik/BRK.Mol Cell Biol. 23 92-103.
Alexander M, Bor YC, Ravichandran KS, Hammarskjold ML, Rekosh D. (2004) Human immunodeficiency virus type 1 Nef associates with lipid rafts to downmodulate cell surface CD4 and class I major histocompatibility complex expression and to increase viral infectivity J Virol. 781685-96.
Forrest ST, Barringhaus KG, Perlegas D, Hammarskjold ML, McNamara CA. (2004) Intron retention generates a novel Id3 isoform that inhibits vascular lesion formation. J Biol Chem. 279 32897-32903
Li, Y. Bor, Y.-C.,Misawa, Y, Xue, Y, Rekosh , D.,and M.-L. Hammarskjold (2006) The Tap/NXF1 Gene Contains a Functional CTE in an Intron that is Retained in an Alternatively Spliced mRNA, Nature 2006 443 234-237
Bor YC, Swartz J, Morrison A, Rekosh D, Ladomery M, Hammarskjold ML. (2006) The Wilms' tumor 1 (WT1) gene (+KTS isoform) functions with a CTE to enhance translation from an unspliced RNA with a retained intron. Genes Dev. 20 1597-1608
Levesque L, Bor YC, Matzat LH, Jin L, Berberoglu S, Rekosh D, Hammarskjold ML, Paschal BM. (2006) Mutations in tap uncouple RNA export activity from translocation through the nuclear pore complex.Mol Biol Cell. 17 931-43.
Bessong PO, Mphahlele J, Choge IA, Obi LC, Morris L, Hammarskjold ML, Rekosh DM. (2006) Resistance Mutational Analysis of HIV Type 1 Subtype C among Rural South African Drug-Naive Patients Prior to Large-Scale Availability of Antiretrovirals. AIDS Res Hum Retroviruses. 12 1306-1312
Olivieri, K.C. BS, Scoggins, R. M., Bor, Y-C, Matthews, A., Mark, B.S. ,Taylor, J., Chenauskas, D., Hammarskjöld, M. , Rekosh D. and Hammarskjold, M.L. (2007) The Envelope Gene is a Cytopathic Determinant of CCR5 Tropic HIV-1, Virology 358 23-38
Swartz JE, Bor YC, Misawa Y, Rekosh D, Hammarskjold ML. (2007) The shuttling SR protein 9G8 plays a role in translation of unspliced mRNA containing a CTE. J Biol Chem. J Biol Chem. 282 19844-19853