Previous Funding:

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Summary:		 RO1 HL56093
NIH/NHLBI
Irving L. Kron, MD
07/01/1997 – 06/30/2007
$1,750,000
Protection of the Pulmonary Vascular Endothelium
This project examines the role of nitric oxide and circulating neutrophils and macrophages in blood-perfused pulmonary ischemia-reperfusion injury using rabbit, rat and mouse models.
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Summary: 		 RO1 HL67780
NIH/NHLBI
Victor E. Laubach, PhD 
04/01/2002 - 03/31/2007
$800,000
Nitric Oxide Regulation of Compensatory Lung Growth
This project examined the role of eNOS and iNOS in post-pneumonectomy compensatory lung growth.
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Summary: 		 Career Investigator Award
American Lung Association of Virginia
Victor E. Laubach, PhD 
07/01/2003 - 06/30/2006
$150,000
Mechanisms of Unequal Lobar Growth in Post-Pneumonectomy Lung Growth
This project studied the individual lobes of the lung after pneumonectomy and compares lung growth and vascular growth among these lobes in the rat model.
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Summary: 		 CNI 04-098
Commonwealth Neurotrama Initiative, Virginia Dept of Rehabilitative Services
John A. Kern, MD
8/1/2002 -7/30/2005
Adenosine A2A Agonists in the Treatment of Acute Spinal Cord Injury
This project examined the use of a synthetic Adenosine A2A agonist to limit histopathologic damage and improve functional outcome following traumatic spinal cord injury.
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Summary: 		 5 R44 NS043093
NIH/NINDS
John A. Kern, MD
9/15/2001 – 6/1/2005
$420,000
A2A Adenosine Agonists as Neuroprotectants
The central goal of this research was to develop a new drug to prevent spinal cord reperfusion injury secondary to aortic clamping that occurs frequently during thoracic surgery.
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Summary: 		 5 RO1 NS39499
NIH / NINDS
John A. Kern, MD 
12/1/2000 – 11/30/2004
Reducing Spinal Cord Injury with Retrograde Perfusion
This study examined different methods of protecting the spinal cord during periods of aortic occlusion.
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Summary: 		 Research Grant
Falk Medical Research Trust
Irving L. Kron, MD
1/1/2001 - 12/31/2004
$585,000
The Role of Inflammation in Serious and Incurable Diseases
This grant examined the role of inflammation in lung and spinal cord ischemia and reperfusion injury.
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Grant in Aid
American Heart Association (National)
Irving L. Kron, MD
1/1/2002 – 12/31/2004
$130,000
Lung Protection Following Transplantation
This project studied the role of white blood cells and NF-kB transcription factor in blood-perfused pig and rat models of lung ischemia-reperfusion injury.

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Summary: 		 T32 HL007849
NIH
Irving L. Kron, MD
01/01/1998- 12/31/2003
$271,622
CardioThoracic Surgery Traninig Grant
To train and develop academic surgeons by providing two protected years in a laboratory full-time conducting hypothesis-driven research.
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Summary: 		 Research Grant
Virginia Thoracic Society
Victor E. Laubach, PhD
7/1/2001 - 6/30/2003
$100,000
Nitric Oxide Regulation of Compensatory Lung Growth
This project examined the role of nitric oxide in mechanisms of post-pneumonectomy compensatory lung growth..
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Research and Development Grant
University of Virginia
Victor E. Laubach, PhD
12/1/2001 - 11/30/2002
$14,343
Nitric Oxide Regulation of Compensatory Lung Growth
This project provided preliminary data for RO1 funding into mechanisms of nitric oxide-mediated compensatory lung growth.

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Summary:		 RO1 HL4824
NIH/NHLBI
Irving L. Kron, MD
4/1/1993 - 3/31/2002
$1,348,046
Living Related Pulmonary Lobar Transplantation
This project studied factors present in the immature host environment which are responsible for lung growth and differentiation and how they stimulate further growth of an already mature lobar transplant.
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Grant-In-Aid
Children's Medical Center, University of Virginia
Curtis G. Tribble, MD
7/1/2001 – 6/30/2002
$10,000
A Long-Term Ventricular Assist Device Utilizing a Magnetic Bearing System and Implantable Physiologic Controller
This proposal outlined the preliminary investigation of a mechanical device designed to support blood flow through either the general or pulmonary circulation.

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Summary:		 Research Grant
American Lung Association
Victor E. Laubach, PhD
7/1/1999 - 6/30/2001
$100,000  (relinquished due to Amer. Heart Assoc. grant below)
Mechanisms of Cellular Growth in Reduced-Size Lung Transplantation
This project examined the role of growth factors, growth factor receptors and cellular proliferation in lung growth after reduced-size lobar transplant using a swine transplant model.
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Summary:		 Grant-In-Aid
American Heart Association (Mid-Atlantic Affiliate)
Victor E. Laubach, PhD
07/1/1999 - 06/30/2001
$160,000
Mechanisms of Cellular Growth in Reduced-Size Lung Transplantation
This project examined the role of growth factors, growth factor receptors and cellular proliferation in lung growth after reduced-size lobar transplant using a swine transplant model.