Robert G. Sawyer, M.D.
Associate Professor
Co-director of the Surgical Trauma Intensive Care Unit
photograph of Dr. Sawyer

Clinical Interests
Liver, kidney, and pancreas transplantation
Surgical infectious diseases

Research Interests
Infectious diseases

Undergraduate and Medical Education
University of Michigan, B.S. (Biomedical Sciences), 1984
University of Michigan, M.D., 1986

Postgraduate Medical Education
University of Virginia Medical Center, Surgical Residency, 1987-1994
Surgical Infectious Disease Fellowship, University of Virginia Medical Center, 1988-1991
Transplant Fellowship, University of Michigan, 1994-1996

Licensure
Virginia
Michigan

Board Certification
American Board of Surgery

Recent Publications
Crabtree TD, Pelletier SJ, Gleason TG, Pruett TL, Sawyer RG. Gender-dependent differences in outcome after the treatment of infection in hospitalized patients. JAMA 1999;282:2143-2148.

Pelletier SJ, Crabtree TD, Gleason TG, Raymond DP, Oh CK, Pruett TL, Sawyer RG. Characteristics of infectious complications associated with mortality after solid organ transplantation. Clin Transplant 2000;14:401-408.

Oh CK, Sawyer RG, Pelletier SJ, McCullough C, Sanfey H, Pruett TL. Implication of advanced donor age on the outcome of liver transplantation. Clin Transplant 2000;14:386-390.

Pelletier SJ, Crabtree TD, Gleason TG, PruettTL, and Sawyer RG. Bacteremia associated with central venous catheter infection is not an independent predictor of outcome. J Am Coll Surg 2000;190:671-680.

Sawyer RG, Pelletier SP, Spencer CE, Pruett TL, Isaacs RB. Increased late hepatic artery thrombosis rate and decreased graft survival after liver transplants with zero cross-reactive group (CREG) mismatches. Liver Transpl 2000;6:229-236.

May AK, Gleason TG, Sawyer RG, Pruett TL. Contribution of Escherichia colialpha-hemolysin to bacterial virulence and to intraperitoneal alterations in peritonitis. Infect Immun 2000;68:176-183.

Pelletier SJ, Iezzoni JC, Crabtree TD, Hahn YS, Sawyer RG, Pruett TL. Prediction of graft fibrosis by clinical parameters and early macrovesicular steatosis after liver transplantation for hepatitis C virus. Liver Transpl 2000;6:44-53.

Claridge JA, Crabtree TD, Pelletier SJ, Butler K, Sawyer RG, Young JS. Persistant occult hypoperfusion is associated with a significant increase in infection rate and mortality in major trauma patients. J Trauma 2000;48:8-14.

Pelletier SJ, Raymond DP, Crabtree TD, Berg CL, Iezzoni JC, Hahn YS, Sawyer RG, Pruett TL. Hepatitis C-induced hepatitis allograft injury is associated with a pretransplant elevated viral replication rate. Hepatology 2000;32:418-426.

Pelletier SJ, Iezzoni JC, Crabtree TD, Raymond DP, Sawyer RG, Hahn YS, and Pruett TL. Pretransplant hepatitis C virus envelope diversity may be predictive of long-term outcome after liver transplantation. Hepatology 2000;32:375-381.

Jin L, Raymond DP, Crabtree TD, Houlgrave CW, Pelletier SJ, Pruett TL, Sawyer RG. Enhanced murine macrophage tumor necrosis factor receptor shedding by CpG in oligodeoxynucleotides. J Immunol 2000;165:5153-5160.

Raymond DP, Crabtree TD, Pelletier SJ, Gleason TG, Banas LE, Patel S, Pruett TL, Sawyer RG. Extremes of white blood cell count do not independently predict outcome among surgical patients with infection. Am Surg 2000;66:1124-1131.

Crabtree TD, Jin L, Raymond DP, Pelletier SJ, Houlgrave W, Gleason TG, Pruett TL, Sawyer RG. Preexposure of murine macrophages to CpG oligonucleotide results in a biphasic TNF-a response to subsequent LPS challenge. Infect Immun 2001;69:2123-2129.

Raymond DP, Pelletier SJ, Crabtree TD, Gleason TG, Pruett TL, Sawyer RG. Impact of bloodstream infection on outcomes among infected, hospitalized surgical patients. Ann Surg 2001;233:549-555.

Oh CK, Pelletier SJ, Sawyer RG, McCullough CS, Pruett TL, and Sanfey HA. Uni- and multi-variate analysis of risk factors for early and late hepatic artery thrombosis after liver transplantation. Transplantation 2001;71:767-772.

Crabtree TD, Pelletier SJ, JL Antevil, Gleason TG, Pruett TL, and Sawyer RG. Cohort study of fever and leukocytosis as diagnostic and prognostic indicators in infected surgical patients. World J Surg 2001;25:739-744.

Sawyer RG, Raymond DP, Pelletier SJ, Crabtree TD, Gleason TG, Pruett TL. Implications of 2,457 consecutive surgical infections entering the year 2000. Ann Surg 2001;233:867-874.

Pelletier SJ, Raymond DP, Iezzoni JC, Berg CL, Sawyer RG, Pruett TL. Improved outcome for HCV recipients with normal serum transaminases after liver transplantation. Trans Proc 2001;33:1397-1398.

Raymond DP, Pelletier SJ, Crabtree TD, Gleason TG, Hamm LL, Pruett TL, Sawyer RG. Impact of a rotating empiric antibiotic schedule on infectious mortality in an intensive care unit. Crit Care Med 2001;29:1101-1108.

Butty SD, Hagspiel KD, Angle JF, Leung DA, Matsumoto AH, Spinosa DJ, Sanfey HA, Sawyer RG, McCullough C, Pruett TL. Proc. Intl. Soc. Mag. Reson. Med 2001;9:1.

Claridge JA, Sawyer RG, G hezel-Ayagh A, Schulman AM, Young JS. The July phenomenon: Fact or fiction. Surgery 2001;130:346-353.

Address
Department of Surgery
PO Box 800709
Charlottesville, Virginia 22908-0709

Email
rws2k@virginia.edu

Telephone
(434) 982-1632

Fax
(434) 924-5539