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Li  Li
Degree(s): MD, PhD
Graduate School: Hunan Medical University; Shanghai 2nd Medical University
Primary Appointment: Associate Professor, Medicine, Nephrology
Research Interests:
Immune response of the kidney to ischemia-reperfusion injury and transplantation.
Email Address: ll3m@virginia.edu
Research Description

Dr. Li Li is interested in the innate and adaptive immune response of the kidney to ischemia-reperfusion injury and transplantation. She works both immune cells in vitro as well as in animal models of kidney ischemia-reperfusion and transplantation. Currently Li Li is studying the mechanism of adenosine 2A agonists on NKT cells, dendritic cells and macrophage subtypes mediating kidney ischemia/reperfusion injury protection.

Selected Publications
  • Li L, Huang L, Vergis AL, Ye H, Bajwa A, Narayan V, Strieter RM, Rosin DL, Okusa MD. IL-17 produced by neutrophils regulates interferon gamma-mediated neutrophil migration in mouse kidney ischemia-reperfusion injury. J Clin Invest. In press, 2010.
  • Li L, Huang LS, Sung SJ, Vergis AL, Rosin DL, Rose C, Lobo PI, Okusa MD. The chemokine receptors CCR2 and CX3CR1 mediate monocyte/macrophage trafficking in kidney ischemia-reperfusion injury. Kidney Int. 74:1526-1537, 2008. (Editorial Commentary: S.Swaminathan and M.D. Griffin. Kidney Int. 74:1509-1511, 2008
  • Li. Li, L. Huang, S. S.J. Sung, Randall Gregg, Vic Engelhard, P.I Lobo, M. D. Okusa. NKT cell activation of PMN Interferon gamma production Induces Injury following Ischemia-Reperfusion. J. Immunol. 178:5899-5911, 2007.
  • Sevigny, C*, Li Li*, A. Awad, L. Huang, M. McDuffie, J. Linden, P. I. Lobo and M.D. Okusa. Activation of Adenosine 2A Receptors Attenuates Allograft Rejection and Alloantigen Recognition J Immunol. 178(7):4240-4249, 2007. *Equal contributors as first author.
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    Contact Information
      Department Address: PO Box 800136
    Charlottesville , VA  22908-0136
      Office Address: PO Box 800133, 
      Office Phone: +1 434-982-0817
      Fax Phone: +1 434-924-9578

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