Eric  R.  Houpt
Degree(s): MD
Graduate School: Emory University
Primary Appointment: Professor, Medicine, Infectious Diseases and International Health
Research Interests:
Molecular diagnostics and Immunology
Email Address: erh6k@virginia.edu
Research Description

Our laboratory is involved in several projects. One is the development of molecular diagnostic tools for infectious diseases. Most work involves developing panels of PCR-based diagnostic tests to detect a full range of enteropathogens, and we utilize these tests at our collaborative field sites in Tanzania and Bangladesh in the context of clinical research. In Tanzania we have laboratories both at the Kilimanjaro Christian Medical Centre in Moshi and also a childhood malnutrition project underway in rural Haydom. Here at UVA we also have a project on the host response to intestinal Entamoeba histolytica infection using a mouse model of amebic colitis that we have developed. The model permits delineation of both innate and acquired immune responses to the parasite. Finally we have a growing program on tuberculosis, specifically on identifying markers for slow response to therapy, which is used in the context of our clinic of complicated Tb patients that I see through the Virginia Department of Health.

Selected Publications
  • Heysell SK, Moore JL, Keller SJ, Houpt ER. Therapeutic drug monitoring for slow response to tuberculosis treatment in a state control program, Virginia, USA. Emerg Infect Dis. 2010 Oct;16(10):1546-53..
  • Guo X, Barroso L, Becker SM, Lyerly DM, Vedvick TS, Reed SG, Petri WA Jr, Houpt ER. Protection against intestinal amebiasis by a recombinant vaccine is transferable by T cells and mediated by gamma interferon. Infect Immun. 2009 Sep;77(9):3909-18.
  • Houpt ER, Guerrant RL. Technology in global health: the need for essential diagnostics. Lancet. 2008 Sep 13;372(9642):873-4.
  • Haque R, Roy S, Kabir M, Stroup S, Mondal D, Houpt E. Giardia assemblage A infection and diarrhea in Bangladesh. J Inf Dis 2005, 192(12):2171-2173.
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    Contact Information
      Office Address: PO Box 800136 MR-6, 1716A, 
      Office Phone: +1 434-243-9326
      Fax Phone: +1 434-924-0075

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