Christopher  M.  Kramer
Degree(s): MD
Graduate School: University of CA, San Francisco
Primary Appointment: Professor, Radiology, Radiology Research
Research Interests:
Cardiovascular MRI, Myocardial Infarction, Myocardial Function, Left Ventricular Remodeling, Myocardial Viability, Coronary Artery Imaging, Atherosclerotic Plaque Imaging
Website: http://www.hsc.virginia.edu/internet/cardiofellows/research/general.research/kramer8-08.cfm
Email Address: ckramer@virginia.edu

Biomedical Sciences Graduate Program(s)
  • Biomedical Sciences Graduate Programs

  • Research Description

    Cardiovascular magnetic resonance imaging is a powerful technology that offers a comprehensive imaging approach to ischemic heart disease. A major focus of our work is on developing clinical applications of cardiovascular MRI. Active clinical protocols include developing a comprehensive MR exam for clinical trials in peripheral arterial disease including atherosclerotic plaque imaging and calf muscle perfusion and energetics at peak exercise. Other clinical studies include quantitative myocardial perfusion imaging in microvascular coronary disease, predicting the development of LV dysfunction from chemotherapeutic agents, quantitative myocardial functional imaging as a measure of dyssynchrony in heart failure, coronary artery and wall imaging, and imaging of left atrial structure and mechanics.


    Selected Publications
  • Pollak AW, Meyer CH, Epstein FH, Jiji RS, Hunter JR, DiMaria JM, Christopher JM, Kramer CM. Arterial spin labeling MRI reproducibly measures peak-exercise calf muscle perfusion: A study in patients with peripheral arterial disease and healthy volunteers. J Am Coll Cardiol Img, 2012;5:1224-1230.
  • Parmar J, Rogers WJ, Mugler J, Baskurt E, Altes TA, Nandalur KR, Stukenborg G, Phillips CD, Hagspiel KD, Matsumoto AH, Dake MD, Kramer CM. MRI of carotid atherosclerotic plaque in clinically suspected acute transient ischemic attack and acute ischemic stroke. Circulation, 2010;122:2031-2038.
  • Patel A, Antkowiak PF, Nandalur KR, West AM, Salerno M, Arora V, Christopher J, Epstein FH, Kramer CM. Assessment of advanced coronary artery disease: advantages of quantitative magnetic resonance perfusion analysis. J Am Coll Cardiol, 2010;56:561-569.
  • West AM, Anderson JD, Meyer CH, Epstein FH, Wang H, Hagspiel KD, Berr SS, Harthun NL, Weltman AL, DiMaria JM, Hunter JR, Christopher JM, Kramer CM. LDL lowering does not improve calf muscle perfusion, energetics, or exercise performance in peripheral arterial disease. J Am Coll Cardiol, 2011;58:1068-76.
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    Contact Information
      Office Address: PO Box 800170 Hospital Expansion Building 4th Floor, Room, 
      Office Phone: +1 434-243-0736
      Fax Phone: +1 434-982-1998

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