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Christopher  M.  Kramer
Degree(s): M.D.
Graduate School: University of CA, San Francisco
Primary Appointment: Professor, Radiology, Radiology Research
Research Interests:
Cardiovascular MRI, Myocardial Infarction, Myocardial Function, Left Ventricular Remodeling, Myocardial Viability, Coronary Artery Imaging, Atherosclerotic Plaque Imaging

Email Address: ckramer@virginia.edu
Biomedical Sciences Graduate Program(s)
  • Biomedical Engineering
    • Research Description

    Cardiovascular magnetic resonance imaging is a powerful new technology that promises to become a comprehensive imaging approach to ischemic heart disease. A major focus of our work is on developing clinical applications of cardiovascular MRI . Active clinical protocols include developing a comprehensive MR exam for clinical trials in peripheral arterial disease including atherosclerotic plaque imaging and calf muscle perfusion and energetics at peak exercise. Other clinical studies include quantitative myocardial perfusion imaging, quantitative myocardial functional imaging as a measure of dyssychrony in congestive heart failure, coronary artery and wall imaging, and dobutamine stress testing with rapid real-time imaging. Another focus of our research is on using cardiovascular MRI in a mouse model of myocardial infarcion to understand the mechanisms underlying LV remodeling after myocardial infarction.

    Selected Publications
  • Anderson JD, Epstein FH, Meyer CH, Hagspiel KH, Wang H, Berr SS, Harthun N, Weltman A, Dimaria JD, West AM, Kramer CM. Multifactorial determinants of functional capacity in peripheral arterial disease: Uncoupling of calf muscle perfusion and metabolism. J Am Coll Cardiol, 2009;54:628-35.
  • Rogers WJ, Meyer CH, Kramer CM. Technology insight: in vivo cell tracking by use of MRI. Nat Clin Pract Cardiovasc Med 2006;3:554-62.
  • Isbell DC, Voros S, Yang Z, DiMaria JM, Berr SS, Epstein FH, French BA, Bishop SP, Wang H, Roy J, Kemp BA, Matsubara H, Carey RM, Kramer CM. Interaction between bradykinin subtype 2 and angiotensin II type 2 receptors during post-MI left ventricular remodeling. Am J Phys, Heart and Circ Phys, 2007;293:H3372-3378.
  • Bove CM, DiMaria JM, Voros S, Conaway MR, Kramer CM. Comparing dobutamine response and myocardial infarct transmurality in the prediction of functional improvement after CABG: Initial experience. Radiology, 2006;240:835-41.
  • PubMed Listings for this Faculty Member
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    Contact Information
      Office Address: PO Box 800170, Hospital Expansion Building, 4th Floor, Ro, 
      Office Phone: +1 434-243-0736
      Fax Phone: +1 434-982-1998

    Other Web sites for this mentor:
    http://www.healthsystem.virginia.edu/people/dop/dopDetail.cfm?drid=593

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