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Jack Knight-Scott, Ph.D.
Assistant Professor of Biomedical Eng.
Box 800759
University of Virginia
Charlottesville, VA 22908
e-mail: jk9c@virginia.edu |
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Education:
B.S., Physics, Eastern Kentucky University, 1986
B.S., Electrical Engineering, University of Kentucky,1986
M.S., Eastern Kentucky University, 1989
Ph.D., Biophysics, Medical College of Wisconsin, 1997
Research Interests:
The primary objectives and applications of our magnetic resonance
spectroscopy (MRS) group is to develop neurospectroscopy for the
chemical characterization of brain tissue in vivo in studying,
diagnosing, and treating neurological diseases and organic mental
disorder. Our current projects include quantifying hippocampal
metabolite changes from glucose-dependent enhancement of visual memory
in individuals with Alzheimer's disease; determining the neuroprotective
effects of hormone replacement therapy in women with multiple sclerosis;
and developing water loading to assess the relationship between the
blood-brain integrity and mild cognition impairment in the elderly.
Current Projects:
- Effects of Orally Administered Glucose on Hippocampal Metabolites and Cognition in Healthy Aging and Alzheimer's disease: a Proton Magnetic Resonance Spectroscopy Study.
- Effect of estrogen replacement therapy for postmenopausal women with MS.
Recent and Representative Publications:
Jack Knight-Scott, Shella D. Keilholz-George, Vu M. Mai, John M. Christopher. Temporal Dynamics of Blood Flow Effects in Half-Fourier Fast Spin Echo 1H Magnetic Resonance Imaging of the Human Lungs. JMRI 14:411–418 (2001).
Jack Knight-Scott. Application of Multiple Inversion Recovery for Suppression of Macromolecule Resonances in Short Echo Time 1H NMR Spectroscopy of Human Brain. Journal of Magnetic Resonance 140, 228–234 (1999). |
