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ImageStream(R) Used for Pioneering Advance in AIDS Research
SEATTLE, July 25 /PRNewswire/
-- Amnis Corporation, a manufacturer of
advanced
instrumentation for the life science research and diagnostics
markets,
announced today the publication of a major new study in the field
of AIDS research.
The pioneering work, involving the development of a
robust murine model for long-term KSHV infection, was
carried out by Dr.
Dean Kedes and colleagues at the University of Virginia
Health System.
KSHV, a gamma herpesvirus, is the etiologic agent of Kaposi's
sarcoma, the
most common
AIDS-associated malignancy worldwide.
"The establishment of this
mouse model for KSHV infection provides a
valuable tool
that will enable us to achieve a better understanding of
longitudinal
patterns of viral gene expression, cell tropism and immune
responses,"
said Dr. Kedes, a member of the University's
Myles H. Thaler
Center for AIDS
and Retrovirus Research. "We believe that this new
information will
help in furthering our ability to understand how this
virus causes
tumors and, in the future, to design better ways of preventing
or treating
them." The lead author of the paper describing the work, Dr.
Christopher Parsons, is also of the University of Virginia
Health System.
"We are extremely gratified
that the ImageStream system was employed
for this
important research," said David Basiji,
Ph.D., Amnis' President
and CEO. "Since
its inception, we have been confident that ImageStream
technology would ultimately
have a direct impact on human health. The
ImageStream system allowed
Dr. Kedes and his colleagues to identify rare
splenocyte subpopulations
containing the virus and quantitate their
numbers
and level of
infection with high specificity and sensitivity."
This research has been the subject
of a previous announcement by the
University of Virginia, which may be
found at
http://www.newswise.com/articles/view/521478/.
Amnis
Corporation, headquartered in Seattle,
WA, develops,
manufactures
and markets
instrumentation for high speed imaging of cells in flow. Its
flagship product,
the ImageStream cell analysis system,
generates six high
resolution
microscopic images of cells as they flow through the instrument
at rates up to 300
cells per second. The system is unique in its ability to
image tens of
thousands of cells in minutes without the need to make
slides. The IDEAS(R)
image analysis package, an integral part of the
ImageStream system, is a
highly sophisticated yet easy to use tool for
processing hundreds of
thousands of images at a time. IDEAS enables highly
advanced research
applications in hematology, immunology, oncology and
provides a
critical foundation for the company's clinical applications
development.
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