Dr. Obrig is a professor of research of internal medicine and nephrology. He has served on committees of more than 35 Ph.D. and five M.S. candidates at the NYS School of Public Health, Albany Medical College and at the University of Rochester. He is also an external examiner at the University of Toronto and Lund University, Sweden and has been a co-mentor to several infectious diseases fellows at the University of Virginia.
Training Background
Dr. Obrig earned his Bachelor of Science degree from West Virginia University and received his Masters in Science and Ph. D. at the University of Illinois at Urbana.
Research Interest
Dr. Obrig research interests include the mechanisms of bacterial pathogenesis. The combined actions of bacterial toxins and host cytokines in vascular disease are being studied with the goal of developing well-designed therapeutic interventions for E. coli O157:H7-associated disease of humans.
Publications
Dr. Obrig's most recent co-authored journal publications include Local anesthetic induced protection against lipopolysaccharide-induced in endothelial cells: the role of mitochondrial adenosine triphosphate-sensitive potassium channels in the journal Anesthesia and Analgesia, 2005, Shiga toxin 2 and LPS induce human microvascular endothelial cells to release chemokines and factors that stimulate platelet function in the journal Infection and Immunity, 73:8306-8316, 2006 and Caspase and bid involvement in Clostridium difficile toxin A-induced apoptosis and modulation of toxinA effects by glutamine and alanyl-glutamine in vivo and in vitro, also in the journal Infection and Immunity. 74:81-87, 2006. See PubMed Listings for Dr. Obrig.