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PEDIATRIC PHARMACOTHERAPY

A Monthly Review for Health Care Professionals

The purpose of this newsletter is to provide a brief, referenced, peer-reviewed source of continuing medication information specifically related to children. The major focus of the material will be the initiation and monitoring of medications in the primary care setting.

Please send comments or questions to Marcia L. Buck, Pharm.D., FCCP mlb3u@Virginia.edu

Index for volumes 1 and 2, January 1995 - December 1996
All newsletters are provided in PDF format unless otherwise noted

Volume 14, January - December 2008

Volume 14, Number 1: Use of Risperidone in Children with Autism, Bipolar Disease, or Schizophrenia
Volume 14, Number 2: Use of Clindamycin in Pediatric Infections
Volume 14, Number 3: New Treatment Options for Attention-Deficit/Hyperactivity Disorder (ADHD): Part I. Transdermal Methylphenidate and Lisdexamfetamine
Volume 14, Number 4: New Treatment Options for Attention-Deficit/Hyperactivity Disorder (ADHD): Part II. Guanfacine

Volume 13, January - December 2007

Volume 13, Number 1: Twelve-year Cumulative Index
Volume 13, Number 2: Use of Aspirin in Children with Cardiac Disease
Volume 13, Number 3: Food and Drug Administration Update: Pediatric Highlights
Volume 13, Number 4: Hydrocortisone for Refractory Hypotension in Neonates
Volume 13, Number 5: Self-Medication by Adolescents
Volume 13, Number 6: Omalizumab for the Management of Refractory Allergic Asthma in Children
Volume 13, Number 7: Intravenous Dihydroergotamine (DHE) for the Treatment of Refractory Migraines
Volume 13, Number 8: Tumor Necrosis Factor Alfa (TNFα) Antagonists for Pediatric Immune-Mediated Diseases
Volume 13, Number 9: Retapamulin: A New Option for Impetigo
Volume 13, Number 10: Drug Metabolism via Cytochrome P450 2D6: Ontogeny and Variation in Children
Volume 13, Number 11: Pediatric Pharmacology Update (Nov/Dec newsletter)

Volume 12, January - December 2006

Volume 12, Number 1: Dexmedetomidine for Sedation in the Pediatric Intensive Care Setting
Volume 12, Number 2: Immunosuppression with Sirolimus after Solid Organ Transplantation in Children
Volume 12, Number 3: Serotonin Syndrome: Pediatric and Neonatal Considerations
Volume 12, Number 4: Routine Hepatitis A Vaccination in the United States
Volume 12, Number 5: Food and Drug Administration Update for Pediatric Health Care Professionals
Volume 12, Number 6: Ertapenem for Prophylaxis and Treatment of Infections in Children
Volume 12, Number 7: Use of Oral Terbinafine in Children
Volume 12, Number 8: Nesiritide for Infants and Children with Heart Failure
Volume 12, Number 9: Human-Bovine Reassortant Rotavirus Vaccine
Volume 12, Number 10: Use of Aminocaproic Acid in Children Undergoing Cardiac Surgery or ECMO
Volume 12, Number 11: Quadrivalent Human Papillomavirus (HPV) Recombinant Vaccine
Volume 12, Number 12: Intraosseous Administration of Drugs in Infants and Children

Volume 11, January - December 2005

Volume 11, Number 1: Ten Year Cumulative Index
Volume 11, Number 2: Use of Carvedilol in Children with Cardiac Failure
Volume 11, Number 3: Recent Actions by the Food and Drug Administration
Volume 11, Number 4 : Pediatric Therapy Update: Azithromycin
Volume 11, Number 5 : Meningococcal Conjugate Vaccine
Volume 11, Number 6: Phenytoin for Seizure Prophylaxis after Traumatic Brain Injury in Children
Volume 11, Number 7: Tetanus, Diphtheria, Acellular Pertussis Booster Vaccination for Adolescents
Volume 11, Number 8: Caspofungin for Refractory Fungal Infections in Infants and Children
Volume 11, Number 9: The Use of Chloral Hydrate in Infants and Children
Volume 11, Number 10: Drug-induced QT Prolongation: Examples from the Pediatric Literature
Volume 11, Number 11 : Zonisamide Use in Pediatrics
Volume 11, Number 12: Combination Measles, Mumps, Rubella, and Varicella Vaccine

Volume 10, January - December 2004

Volume 10, Number 1: Aldosterone Inhibitors in Infants and Children
Volume 10, Number 2: Sildenafil for the Treatment of Pulmonary Hypertension in Children
Volume 10, Number 3: Recent Revisions in Drug Labeling for Children
Volume 10, Number 4: Therapeutic Uses of Codeine in Pediatric Patients
Volume 10, Number 5: Assessing Information from the Vaccine Adverse Event Reporting System (VAERS)
Volume 10, Number 6: Global Poliovirus Eradication and the Inactivated Poliovirus Vaccine
Volume 10, Number 7: Use of Metformin in Pediatric Patients
Volume 10, Number 8: Current Recommendations for Influenza Vaccination in Children
Volume 10, Number 9 : Update on Palivizumab
Volume 10, Number 10: Octreotide for the Management of Chylothorax in Infants and Children
Volume 10, Number 11: Use of Rifampin in Pediatric Infections
Volume 10, Number 12: Aripiprazole Use in Children and Adolescents

Volume 9, January - December, 2003

Volume 9, number 1: Eight Year Cumulative Index
Volume 9, number 2: The Use of Milrinone in Infants and Children
Volume 9, number 3: Clinical Applications for Botulinum Toxin Type A in Pediatric Patients
Volume 9, number 4: A New Alternative for the Treatment of Attention-Deficit/Hyperactivity Disorder
Volume 9, number 5: Immunosuppression with Tacrolimus after Solid Organ Transplantation in Children
Volume 9, number 6: Linezolid Use for Resistant Gram-positive Infections in Children
Volume 9, number 7: Amlodipine Use in Pediatric Hypertension
Volume 9, number 8: Immunizations for Adolescents
Volume 9, number 9: Low-dose Vasopressin Infusions for Vasodilatory Shock
Volume 9, number 10: Doxycycline for Pediatric Infections
Volume 9, number 11: The Use of Melatonin in Children with Sleep Disturbances
Volume 9, number 12: Recent Advances in Pediatric Pharmacokinetics

Volume 8, January - December, 2002

Volume 8, number 1: Food and Drug Administration Update for Pediatric Practitioners
Volume 8, number 2: Methylphenidate: New Information and New Options
Volume 8, number 3: Amphetamines in the Treatment of Attention-Deficit/Hyperactivity Disorder
Volume 8, number 4: New Agents and Second-line Therapies for Attention-Deficit/Hyperactivity Disorder
Volume 8, number 5: Topical Macrolactam Immunomodulators for Atopic Dermatitis
Volume 8, number 6: Acyclovir for Neonatal and Pediatric Viral Infections
Volume 8, number 7: Levetiracetam for the Treatment of Partial Seizures
Volume 8, number 8: Naloxone for the Reversal of Opioid Adverse Effects
Volume 8, number 9: HMG-CoA Reductase Inhibitors for the Treatment of Hypercholesterolemia in Children and Adolescents
Volume 8, number 10: Pediatric Use of Gabapentin
Volume 8, number 11: Pediatrics Use of REcombinant Human Erythropoietin
Volume 8, number 12: Black Box Warnings: Implications for Pediatric Health Care Providers

Volume 7, January - December, 2001

Volume 7, number 1: Six-year Cumulative Index to Pediatric Pharmacotherapy
Volume 7, number 2: Oseltamivir: A New Option for the Management Influenza in Children
Volume 7, number 3: 2001 Pediatric Vaccine Update
Volume 7, number 4: The second-generation (peripherally-selective) antihistamines in children
Volume 7, number 5: Intranasal steroids for children with allergic rhinitis
Volume 7, number 6: Topiramate for the Management of Seizures in Children
Volume 7, number 7: Isotretinoin: Improving Patient Education and Reducing Risk
Volume 7, number 8: Using the Atypical Antipsychotic Agents in Children and Adolescents
Volume 7, number 9: Perioperative use of high-dose rectal acetaminophen
Volume 7, number 10: Vitamin K for the Prevention of Bleeding in Newborns
Volume 7, number 11: Oxcarbazepine Use in Children and Adolescents
Volume 7, number 12: Amiodarone Use in Children

Volume 6, January - December, 2000

Volume 6, number 1: Midazolam: use in the pediatric intensive care population
Volume 6, number 2: Mirtazapine: potential advantages in adolescents with depression associated with chronic illness
Volume 6, number 3: Preventing acetaminophen overdosage
Volume 6, number 4: Ibuprofen-associated renal toxicity in children
Volume 6, number 5: Propofol usage in children: weighing the benefit and risk
Volume 6, number 6: Clostridium difficile
Volume 6, number 7: Managing iatrogenic opiate dependence with methadone
Volume 6, number 8: Pneumococcal conjugate vaccine
Volume 6, number 9: Aprostadil (PGE₁) for maintaining ductal patency
Volume 6, number 10: Rocuronium for tracheal intubation
Volume 6, number 11: Patient-Controlled Analgesia: Guidelines for Use in Children
Volume 6, number 12: The FDA Modernization Act of 1997: Impact on Pediatric Medicine

Volume 5, January - December, 1999

Volume 5, number 1: Index of volumes 1 - 4
Volume 5, number 2: A new Rotavirus vaccine: Rotashield
Volume 5, number 3: Lamotrigine in the treatment of seizures during childhood
Volume 5, number 4: Use of Proton Pump Inhibitors in Children
Volume 5, number 5: Cefepime
Volume 5, number 6: The Internet as a Source of Pediatric Medication Information
Volume 5, number 7: Cromolyn and Nedocromil in Children with Asthma
Volume 5, number 8: Alteplase (rt-PA) Use in Infants and Children
Volume 5, number 9: Vecuronium: its role in the Pediatric Intensive Care Unit
Volume 5, number 10: Preventing Medication Errors in Children
Volume 5, number 11: Infliximab: a new therapy for Crohn's disease
Volume 5, number 12: Recent Actions by the Food and Drug Administration (FDA)

Volume 4, January - December, 1998

Volume 4, number 1: Treatment of Intravenous Extravasations
Volume 4, number 2: Use of Famotidine in Infants and Children
Volume 4, number 3: Helping Families avoid Accidental Poisonings
Volume 4, number 4: Trimethoprim-sulfamethoxazole: a Review of Use in Children
Volume 4, number 5: Alternative therapy - focus on herbal products
Volume 4, number 6: Drug-induced photosensitivity
Volume 4, number 7: Meropenem: an alternative for broad-spectrum anti-bacterial coverage
Volume 4, number 8: Mycophenylate mofetil: use in pediatrics
Volume 4, number 9: Palivizumab: Use in the Prevention of Respiratory Syncytial Virus Infections
Volume 4, number 10: Montelukast: a selective leukotriene receptor antagonist
Volume 4, number 11: Erythema Multiforme: Stevens-Johnson Syndrome and Toxic Epidermal Necrolysis
Volume 4, number 12: Ciprofloxacin use in children: a review of recent findings

Volume 3, January - December, 1997

Volume 3, number 1: Index for volumes 1 and 2, January 1995 - December 1997
Volume 3, number 2: Ceftriaxone in Children
Volume 3, number 3: Valproic Acid in the treatment of Pediatric Seizures
Volume 3, number 4: Vitamin and Mineral Supplements for Children in the United States
Volume 3, number 5: The Cytochrome P450 System and its Effect on Drug Metabolism
Volume 3, number 6: Using Low-Molecular-Weight Heparin in Infants and Children
Volume 3, number 7: Vaccine Update: New Policies and Products
Volume 3, number 8: Improving Compliance with Medication Regimens
Volume 3, number 9: The use of 5-HT₃ antagonists in the prevention of nausea and vomiting in children
Volume 3, number 10: Prevention and treatment of respiratory syncitial virus
Volume 3, number 11: Pharmacology Literature Review
Volume 3, number 12: Fluconazole - a review of its use in children

Volume 2, January - December, 1996

Volume 2, Number 1: Topical Corticosteroids in Children
Volume 2, Number 2: Macrolide Antibiotics
Volume 2, Number 3: Preventing Pediatric Poisonings
Volume 2, Number 4: Maternal Medication Use During Breastfeeding
Volume 2, Number 5: Albuterol: A Review of its Use in Children with Asthma
Volume 2, Number 6: A Comparison of the Oral Cephalosporins
Volume 2, Number 7: Therapy Review: Antipyretics
Volume 2, Number 8: Phenytoin: Optimizing Therapy in Children
Volume 2, Number 9: A Guide to Pharmaceutical Excipients (Inert Ingredients)
Volume 2, Number 10: The Use of Selective Serotonin Re-uptake Inhibitors in Children and Adolescents
Volume 2, Number 11: Carbamazepine: A Review of its Use in Children with Epilepsy
Volume 2, Number 12: Medications for Pediatric and Neonatal Advanced Life Support

Volume 1, January - December, 1995

Volume 1, Number 1: Therapy Review: Warfarin (Coumadin)
Volume 1, Number 2: Vancomycin: old controversies and new issues
Volume 1, Number 3: Adverse Drug Reactions
Volume 1, Number 4: Cyclosporin
Volume 1, Number 5: Drug-Nutrient Interactons
Volume 1, Number 6: Proper Storage of Vaccines to Maintain Potency
Volume 1, Number 7: Therapeutic Drug Monitoring
Volume 1, Number 8: Treating Lice and Scabies Infestations
Volume 1, Number 9: Antihistamines for the treatment of Allergic Rhinitis in Children
Volume 1, Number 10: Diuretics in Children
Volume 1, Number 11: The FDA Drug Approval Process
Volume 1, Number 12: Hyperactivity Disorder