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Cato T. Laurencin, M.D., Ph.D.
Most recent publications: Nair, L.S., Lee, D.A., Dender, J.D., Barrett, E.W., Grish, Y, Brown, P.W., Allcock, H.R. and Laurencin, C.T.: Synthesis, characterization, and osteocompatibility evaluation of novel alanine-based polyphosphazenes. J. Biomed Mater Res A. 2005 Nov 1; 76A (1):206-213. Laurencin, C.T. and Freeman, J.W.: Ligament tissue engineering: an evolutionary materials science approach. Biomaterials. 2005 Dec; 26(36): 7530-6 Cooper, J.A., Lu, H.H., Ko, F.K., Freeman, J.W. and Laurencin, C.T.: Fiber-based tissue-engineered scaffold for ligament replacement: design considerations and in vitro evaluation. Biomaterials. 2005 May; 26(13):1523-32. Lu H.H., Cooper, J.A. Jr., Manuel, S., Freeman, J.W., Attawia, M.A., Ko, F.K. and Laurencin, C.T.: Anterior cruciate ligament regeneration using braided biodegradable scaffords: in vitro optimization studies. Biomaterials. 2005 Aug; 26(23):4805-16. El-Amin, S.F., Kofron, M.D., Attawia, M.A., Lu, H.H., Tuan, R.S. and Laurencin, C.T.: Molecular regulation of osteoblasts for tissue engineering bone repair. Clin Orthop Relat Res. 2004 Oct;(4270:220-5. Nair, L.S., Bhattacharyya, S., Bender, J.D., Greish, Y., Brown, P.W., Allcock, H.R. and Laurencin, C.T.: Fabrication and optimization of methylphenoxy substituted polyphoshazene nanofibers for biomedical applications. Biomacromolecules. 2004 Nov-Dec;5 (6):2212-20. Kofron, M.D., Li, X. and Laurencin, C.T.: Protein- and gene-based tissue engineering in bone repair. Curr Opin Biotechnol. 2004 Oct; 15(5):399-405. Yu, X, Botchwey, E.A., Levine, E.M., Pollack, S.R. and Laurencin, C.T.: Bioreactor-based bone tissue engineering:the influence of dynamic flow on osteoblast phenotype expression and matrix mineralization. Proc Natl Acad Sci U S A. 2004 Aug 3;101(31): 11203-8. Katti,D.S., Robinson, K.W., Ko, F.K. and Laurencin, C.T.: Bioresorbable nanofiber-based systems for wound healing and drug delivery:optimization of fabrication parameters. J Biomed Mater Res. 2004 Aug 15;70B(2):286-96. Khan, Y.M., Katti, D.S. and Laurencin, C.T.: Novel polymer-synthesized ceramic composite-based system for bone repair:an in vitro evaluation. J Biomed Mater Res A. 2004 Jun 15; 69(4):728-37. Botchwey, E.A., Pollack, S.R., Levine, E.M., Johnston, E.D. and Laurencin, C.T.: Quantitative analysis of three-dimensional fluid flow in rotating bioreactors for tissue engineering. J Biomed Mater Res A. 2004 May 1; 69(2):205-15. Laurencin, C.T. and Katti,D.S.: Repair and restore with tissue engineering. IEEE Eng Med Biol Mag. 2003 Sep-Oct; 22(5):57-54. Botchwey, E.A., Dupree, M.A., Pollack, S.R., Levine, E.M. and Laurencin, C.T.: Tissue engineered bone: measurement of nutrient transport in three-dimensional matrices. J Biomed Mater Res A. 2003 Oct 1; 67(1):357-67. Kofron, M.D. and Laurencin, C.T.: Development of a calcium phosphate co-precipitate/poly(lactide-co-glycolide) DNA delivery system: release kinetics and cellular transfection studies. Biomaterials. 2004 Jun; 25(13):2637-43. Lu, H.H., El-Amin, S.F., Scott, K.D. and Laurencin, C.T.: Three-dimensional, bioactive, biodegradable, polymer-bioactive glass composite sacffolds with improved mechanical propperties support collagen synthesis and mineralization of human osteoblast-like cells in vitro. J Biomed Mater Res A. 2003 Mar 1; 64(3):465074. Laurencin, C.T., Ambrosio, M.A., Borden, M.D., Cooper, J.A.: "Tissue Engineering: Orthopaedic Application." In Annual Reviews of Biomedical Engineering. Yarmush, M. (ed.) Palo Alto: Annual Reviews pp. 19-46 (1999) Attawia, M.A., Uhrich, K., Herbert, K.M., Langer, R., and Laurencin, C.T.: Proliferation, morphology, and protein expression by osteoblasts cultured on poly(anhydride-co-imides). Applied Biomat. 48, 322-327, 1999 Uhrich, K.E., Larrier, D.R., Ibim, S.E.M., Langer, R., and Laurencin, C.T.: In vivo degradation characteristics of poly(anhydride-co-imides) Biomaterials 19, 2045-2050 (1998) Ibim, S.E., El-Amin, S.F., Goad, M.E.P., Ambrosio, A.A., Allcock, H., and Laurencin, C.T.: In vitro release of colchicine using polyphosphazenes: the development of delivery systems for musculoskeletal use. Pharm. Dev. Technol. 3:55-62 (1998). Laurencin, C.T., Borden, M.D., Attawia, M.A., Ko, f., and Morrill, G.M.: Polymer based tissue engineering of bone. Polymer Preprints 39 (2) 122-123, 1998. Ibim, S.E.M.,Uhrich, K.E.,Brunson, El-Amin, S.F., R., Langer, R.S., and Laurencin, C. T. Preliminary in vivo report on the osteocompatibility of Poly(anhydride-co-imides) evaluated in a Tibial Model. Applied Biomat. 43, 374-379, 1998 Ibim, S.E.M.,Uhrich, K.E.,Brunson, R., El-Amin, S.F., Langer, R.S., and Laurencin, C.T.: Poly(anhydride-co-imides) In vivo subcutaneous biocompatibility. Biomaterials 19, 941-951, (1998) Laurencin, C., Attawia, M., and Botchwey, E.: Cell-material systems for anterior cruciate ligament regeneration. In Vitro Cell. Dev. Biol. 34:90-92 (1998). Ibim, S.E.M., Ambrosio, A.M.A., Kwon, M.S., El-Amin, S.F., Allcock, H.R., and Laurencin, C.T.: Novel polyphosphazene/poly(lactide-co-glycolide) blends: miscibility and degradation studies. Biomaterials 18:1565-1569 (1997). Anseth, K.S., Svaldi, D.C., Laurencin, C.T., and Langer, R.: Photopolymerization of novel degradable networks for orthopaedic applications, ACS Symposium Series: Advances in photopolymerizations. Bowman, C., Pfeiffer, R., and Scranton, A. (eds.). ACS Symposium Series 673:189-202 (1997). Uhrich, K.E., Thomas, T.T., Laurencin, C.T., and Langer, R.: In vitro degradation of poly(anhydride-co-imides) containing trimellitylimidoglycine J. Appl. Polym. Sci. 63:1401-1411 (1997). Ibim, S.E.M., Ambrosio, A.A., Larrier, D., Allcock, H.R., and Laurencin, C.T.: Controlled macromolecule release from polyphosphazene matrices. J. Controlled Release 40:31-39 (1996). Laurencin, C.T., El-Amin, S.F., Ibim, S.E., Attawia, M.A., Willoughby, D.A., Allcock, H., and Ambrosio, A.A.: A highly porous three-dimensional polyphosphazene polymer matrix for skeletal tissue regeneration. J. Biomed. Mater. Res. 30:133-138 (1996). Laurencin, C.T., Stephens, S., and Altchek, D.W.: Arthroscopic Bankart repair using a degradable tack: follow up in patients using optimized indications. Clin. Ortho. Rel. Res. 332:132-137 (1996). Seidel, J., Uhrich, K.E., Laurencin, C.T., and Langer, R.: Erosion of poly(anhydride-co-imides): a preliminary mechanistic study. J. Appl. Polym. Sci. 62:1277-1283 (1996). Laurencin, C.T., Attawia, M., Elgendy, H., and Herbert, K.: Tissue engineering for bone using degradable polymers: the creation of mineralized matrices. Bone 19s:93-99 (1996). Laurencin, C.T., Ferriter, P., and Millis, M.: Incomplete proximal osteotomy for the treatment of angular deformities of the tibia. Clin. Ortho. Rel. Res. 327:218-224 (1996). Attawia, M.A., Uhrich, K.E., Botchwey, E., Langer, R., and Laurencin, C.T.: In vitro bone biocompatibility of poly(anhydride-co-imides) containing pyromellitylimidoalanine J. Ortho. Res. 14:445-454 (1996). Uhrich, K.E., Larrier, D.R., Laurencin, C.T., and Langer, R.: In vitro degradation characteristics of poly(anhydride-co-imides) containing pyromellitylimidoalalnine. J. Polym. Sci., Part A: Polym. Chem. 34:1261-1269 (1996). Devin, J., Attawia, M., and Laurencin, C.: Three-dimensional porous polymer-ceramic matrices for use in bone repair. J. Biomat. Sci. Polym. Edn. 661-669 (1996). |
