Quanjun Cui, M.D.; M.S.

 

 

Faculty Rank:

Assistant Professor 

M.D. Degree:

Henan Medical University, 1984

Residency:

Orthopaedic Surgery, University of Virginia

Fellowship:

Adult Reconstruction Fellowship, University of Virginia; Trauma Fellowship, University of Bern

Certification:

Clinical Interests:

Total hip and knee replacement, Osteotomy for young arthritic hip and knee, complex lower extremity fractures and complications.

Research Interests:

Cellular and gene therapy for musculoskeletal diseases, osteonecrosis and fractures.  Development of novel composite bone graft sustitutes for the treatment of fractures and bone defects.  Pathogenesis and treatment of osteonecrosis of the femoral head.

BIBLIOGRAPHY (selected publications):

1.      Cui, Q., Wang, G.-J., Balian, G.:  Steroid-induced adipogenesis in a pluripotential cell line from bone marrow.  The Journal of Bone and Joint Surgery 79 (A): 1054-1063, 1997.

2.      Cui, Q., Wang, G.-J., Su, C.-C., Balian, G.: The Otto Aufranc Award.  Lovastatin prevents steroid-induced adipogenesis and osteonecrosis.  Clinical Orthopaedics and Related Research 344:8-19, 1997.

3.      Wang, G-J., Cui, Q., Balian, G.:  The pathogenesis and prevention of steroid-induced osteonecrosis.  The Nicolas Andry Award paper.  Association of Bone and Joint Surgeons.  Clin Orthop Rel Res.  370:295-310, 1998.

4.      Cui, Q., Wang, G-J., Balian, G.: Pluripotential marrow cells produce adipocytes when transplanted into steroid treated mice. Connective Tissue Research, 41(1): 45-46, 2000.

5.      Dahir, G., Cui, Q., Simon, C.,  Anderson, P., Joyner, C., Triffitt, J.T., Balian, G.: Pluripotential mesenchymal cells repopulate the bone marrow and retain osteogenic properties. Clinical Orthopaedics and Related Research: 379S:s134-s145, 2000.

6.      Cui, Q., Xiao, Z.M., Balian, G., Wang, G-J.: Comparison of lumber spine fusion using mixed and cloned marrow cells. Spine (26): 2305-10, 2001.

7.      Wang, Y., Li, Y., Mao, K., Li, J., Cui, Q., Wang, G.J.: Alcohol induced adipogenesis in bone and marrow: a possible mechanism for osteonecrosis. Clinical Orthopaedics and Related Research (410): 213-224, 2003.

8.      Li, X., Cui, Q., Kao, C., Wang, G.J., Balian, G.: Lovastatin inhibits adipogenic and stimulates osteogenic differentiation by suppressing PPARg2 and increasing Cbfa1/Runx2 expression in bone marrow mesenchymal cell culture. Bone (33) 652-659, 2003.

9.      Li, X., Jin, L., Cui, Q., Wang, GJ., Balian, G.: Steroid effects on osteogenesis through mesenchymal cell gene expression. Osteoporosis international 16(1):101-8, 2005 Jan.

10.   Cui, Q., Milbrandt, T.,  Millington, S., Anderson, M., Hurwitz, S.: Treatment of post-traumatic capsulitis of the ankle: A case series. Foot and Ankle International. 26 (8): 602-6, 2005 Aug

11.   Cui, Q., Xiao, Z., Li, X., Saleh, K.J., Balian,G.: Use of genetically engineered bone-marrow stem cells to treat femoral defects: an experimental study. J Bone Joint Surg Am. 2006 Nov; 88 Suppl 3:167-72.

12.   Myers, T. G., Cui, Q., Kuskowski, M., Mihalko, W., Saleh, K.: Results of Total and Unicompartmental Knee Arthroplasty for Avascular Necrosis and Spontaneous Osteonecrosis of the Knee. J Bone Joint Surg Am. 2006 Nov; 88 Suppl 3:76-82.

13.   Cui Q., Wang Y., Saleh K.J., Wang, G.W., Balian G.: Alcohol-induced adipogenesis in a cloned bone-marrow stem cell. J Bone Joint Surg Am. 2006 Nov; 88 Suppl  3:148-54.

14.  Seyler, T.M., Cui, Q., Mihalko, W.M., Mont, M.A., Saleh, K.J.: Advances of hip arthroplasty in treatment of osteonecrosis.  AAOS Instruction Course Lecture. 2006.  

Book Chapters:

  1. Wang, G.J., Cui, Q.  The pathogenesis of steroid-induced osteonecrosis and the effect of lipid-clearing agents on this mechanism.  In Osteonecrosis: Etiology, Diagnosis and Treatment.  Urbaniak, J.R., Jones, J.P. (Eds.), American Academy of Orthopaedic Surgeons, 1st Ed., Rosemont, IL, 1997, pp 159-166.
  2. Cui, Q., Xiao, Z.M., Balian, G., Wang, GJ.: Use of a Cloned Osteoprogenitor Cell in Spine Fusion.  In: Advances in Spinal Fusion: Molecular Science, Biomechanics, and Clinical Management.  Lewandrowski, K.U., Wise, D.L., Trantolo, D.J., Yaszemski,M.J., and White,A.A.(Eds.), Marcel Dekker, Cambridge, MA. Chapter 8, PP93-102, 2003.
  3. Azer, NM., Cui, Q., Chang, IL., Whitman, TL., Hahn, C., Wang, GJ., Balian, G.: Growth factor delivery by a cloned multipotent cell from bone marrow stoma potentiates bone repair. In: Tissue Engineering and Novel Delivery Systems. Editors: M.J. Yaszemski, et al., Marcel Dekker, Cambridge, MA. Chapter 20, PP463-474, 2004.

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