Charles H. Askew
Neuroscience Graduate Student
Department of Neuroscience
Education
B.A. University of Pennsylvania, 2004
I received my B.A. in Biological Basis of Behavior from the University of Pennsylvania, and as an undergraduate I completed a senior thesis project in the Auditory Research Lab where I continued to work as a post-baccalaureate student/ researcher. I began graduate school at the University of Virginia in fall of 2008 and joined the Holt/Géléoc lab in spring 2009. My research in the lab focuses on the physiology of hair cells in the auditory system. I hope to answer some functional questions using in vivo gene transfer and whole cell patch clamp techniques. Specifically, I'm interested in potassium channels and their role in hearing and deafness. By delivering copies of wild-type potassium channel genes into hair cells, I hope to rescue hair cell and auditory function. I am also interested in teasing apart factors that regulate potassium channel activation by comparing voltage-gated currents in WT and transfected hair cells, as well as heterologous cells transfected with potassium channel genes. Ultimately, my aim is to demonstrate whether gene transfer could be useful as a technique to restore hair cell function in patients with genetic inner ear dysfunction.
Contact information
Email: cha3j@virginia.edu
Lab: (434) 243-9499
Fax: (434) 982-4380
Mailing Address
University of Virginia
Department of Neuroscience
Box 801392
Charlottesville, VA 22908
Delivery Address
University of Virginia
409 Lane Rd
MR4 Building, Room 5126
Charlottesville, VA 22908
Holt / Géléoc Lab Home