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Patrice  G.  Guyenet
Degree(s): Ph.D.
Graduate School: University of Paris, France
Primary Appointment: Professor of Pharmacology
Research Interests:
Neural Control of Blood Pressure and Respiration

Email Address: pgg@virginia.edu


Biomedical Sciences Graduate Program(s)
  • Neuroscience
  • Molecular Medicine

  • Research Description

    My research is a branch of Integrative Neuroscience, a discipline that seeks to understand how the brain processes specific types of information. The laboratory studies how the mammalian brain regulates respiration and blood pressure, two physiological processes that are dysfunctional in very common diseases (hypertension, obesity, apneic syndromes, heart failure, etc.). The work consists of identifying relevant neuronal networks in rodents using electrophysiologic and neuroanatomic methods. The main focus is on a region of the brainstem that provides the chemical drive to breathe and contains the neurons that maintain blood pressure.


    Selected Publications
  • Takakura AC, Moreira TS, Colombari E, West GH, Stornetta RL, & Guyenet, PG (2006) Peripheral chemoreceptor inputs to retrotrapezoid nucleus (RTN) CO2-sensitive neurons in rats. J Physiol (London) 572: 503-523.
  • Guyenet, PG (2006) The sympathetic control of blood pressure. Nat Rev Neurosci 7: 335-346.
  • PG Guyenet, DK Mulkey, RL Stornetta, DA. Bayliss (2005) Regulation of ventral surface chemoreceptors by the central respiratory pattern generator. J Neurosci 25: 8938-8947.
  • DK Mulkey, RL Stornetta, MC Weston, JR Simmons, A Parker, DA. Bayliss and PG Guyenet. (2004) Respiratory control by ventral surface chemoreceptors. Nature Neuroscience 7: 1360-1369.
  • PubMed Listings for this Faculty Member

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    Contact Information
      Office Address: PO Box 800735, Jordan Hall 5th Fl., 5240, 
      Office Phone: +1 434-924-9974
      Fax Phone: +1 434-982-3878
      Home Phone: +1 434-987-2706

    Other Websites for this mentor:
    http://www.healthsystem.virginia.edu/internet/pharmacology/Faculty/guyenetlab.cfm

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