Pathogenesis and Infectious Disease

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The Pathogenesis group in the Microbiology Department studies molecular mechanisms of initiation and progression of infection by viral, bacterial, fungal and protozoan pathogens.

Investigators in the Myles H. Thaler Center focus on viral pathogens such as:

HIV
HTLV-1
KSHV

Among the infectious agents studied by others in the department are:

Herpes simplex virus
Marine Cytomegalovirus
Yersinia pseudotuberculosis
Pseudomonas aeruginosa
Helicobacter pylori
Escherichia coli
Entamoeba histolytica
Candida albicans
Mycobacterium tuberculosis
Bacillus anthracis

These studies might also be organized under the Infectious Diseases Program.

Microbiology Primary Faculty
Amy H. Bouton, Ph.D. Signaling Pathways that Regulate Tumor Growth, Metastasis, and Response to Anticancer Agents; Adhesion Signaling In Macrophages; Bacteria-Host Cell Interactions Jay C. Brown, Ph.D. Structure and Assembly of the Herpes Virus Capsid Michael G. Brown, Ph.D. NK Cells and Viral Immunity Ian J. Glomski, Ph.D. Elucidating the molecular mechanisms of B. anthracis pathogenesis; detection and prevention of anthrax.	Joanna B. Goldberg, Ph.D. Mechanisms of Bacterial Pathogenesis Marie-Louise Hammarskjold, M.D., Ph.D. Post Transcriptional Gene Regulation and the Molecular Biology of Human Retroviruses David M. Rekosh, Ph.D. Human Immunodeficiency; Virus Gene Expression Julie D. Turner, Ph.D. Cell biological dissection of the mechanism of HIV/M. tuberculosis synergy

Microbiology Primary Faculty

Amy H. Bouton, Ph.D.
Signaling Pathways that Regulate Tumor Growth, Metastasis, and Response to Anticancer Agents; Adhesion Signaling In Macrophages; Bacteria-Host Cell Interactions
Jay C. Brown, Ph.D.
Structure and Assembly of the Herpes Virus Capsid
Michael G. Brown, Ph.D.
NK Cells and Viral Immunity
Ian J. Glomski, Ph.D.
Elucidating the molecular mechanisms of B. anthracis pathogenesis; detection and prevention of anthrax.

Joanna B. Goldberg, Ph.D.
Mechanisms of Bacterial Pathogenesis
Marie-Louise Hammarskjold, M.D., Ph.D.
Post Transcriptional Gene Regulation and the Molecular Biology of Human Retroviruses
David M. Rekosh, Ph.D.
Human Immunodeficiency; Virus Gene Expression
Julie D. Turner, Ph.D.
Cell biological dissection of the mechanism of HIV/M. tuberculosis synergy

Joint Faculty
Kevin C. Hazen, Ph.D. Fungal pathogenesis. Fungal surface proteins and hydrophobicity. Dean H. Kedes, M.D., Ph.D. Human Herpes virus Associated with Kaposi's Sarcoma Barbara J. Mann, Ph.D. Associate Professor of Medicine Pathogenicity of Francisella tularensis and the human parasite Entamoeba histolytica, vaccines	William A. Petri, Jr., M.D., Ph.D. Professor and Division Chief of Medicine Molecular Mechanisms of Pathogenesis of Parasitic Infection Judith M. White, Ph.D. Professor of Cell Biology Virus Entry Into Cells; ADAMs in Early Development

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