immunology

Immunology

The Immunology group in the Microbiology Department comprises the central core of the Beirne B. Carter Center for Immunology Research. Research in immunology focuses on:

molecular analysis of the control of lymphocyte growth and differentiation
structure and function of MHC molecules
nature of antigens

antigen-antibody interactions
genetic control of the immune response
immune response to infectious agents
allergens and autoimmune diseases

The study of Immunology has changed from a descriptive discipline focusing on the whole organism to a fundamental science that uses modern cellular and molecular techniques. The understanding of the workings of the immune system is revolutionizing the control of infection, autoimmunity, allergy, and cancer. Breakthroughs in technology and in related fields set the stage for astonishing discoveries and for the treatment of a variety of human diseases.

Microbiology Primary Faculty
Timothy P. Bender, Ph. D. Professor of Microbiology Regulation of gene expression during lymphocyte development Alison K. Criss, Ph.D Assistant Professor of Microbiology Cellular and molecular mechanisms of Neisserial pathogenesis; infection of host cells by pathogenic Neisseria Victor H. Engelhard, Ph.D. Professor of Microbiology Immune responses to tumors and immunotherapy / Impact of self-tolerance on anti-tumor immunity / Processing and presentation of MHC-restricted antigens Loren D. Erickson, Ph.D. Assistant Professor of Microbiology Cellular and molecular mechanisms of B lymphocyte function; Genetic susceptibility in systemic lupus erythematosus and multiple myeloma; Immunotherapeutics in the treatment of B cell disorders Ian J. Glomski, Ph.D. Assistant Professor of Microbiology Elucidating the molecular mechanisms of B. anthracis pathogenesis; detection and prevention of anthrax. Joanna B. Goldberg, Ph.D. Professor of Microbiology Mechanisms of Bacterial Pathogenesis Young S. Hahn, Ph.D. Associate Professor of Microbiology Immune Suppression by Hepatitis C Virus	Marie-Louise Hammarskjold, M.D., Ph.D. Professor of Microbiology Post Transcriptional Gene Regulation and the Molecular Biology of Human Retroviruses Ulrike M. Lorenz, Ph.D. Associate Professor of Microbiology Involvement of the protein tyrosine phosphatase SHP-1 in signal transduction pathways Marcia J. McDuffie, M.D. Professor of Microbiology Genetic analysis of autoimmunity David W. Mullins, Ph.D. Assistant Professor of Microbiology Immunotherapy; Tumor Immunology Sarah (Sally) J. Parsons, Ph.D. Professor of Microbiology Molecular mechanisms of Src family tyrosine kinases in mitogenesis, tumorigenesis, and neuronal activity. Kodi S. Ravichandran, B.V.Sc., Ph.D. Professor of Microbiology Intracecellular signaling in lymphocytes and phagocytes David M. Rekosh, Ph.D. Professor of Microbiology Human Immunodeficiency; Virus Gene Expression

Microbiology Primary Faculty

Timothy P. Bender, Ph. D.
Professor of Microbiology
Regulation of gene expression during lymphocyte development
Alison K. Criss, Ph.D
Assistant Professor of Microbiology
Cellular and molecular mechanisms of Neisserial pathogenesis; infection of host cells by pathogenic Neisseria
Victor H. Engelhard, Ph.D.
Professor of Microbiology
Immune responses to tumors and immunotherapy / Impact of self-tolerance on anti-tumor immunity / Processing and presentation of MHC-restricted antigens
Loren D. Erickson, Ph.D.
Assistant Professor of Microbiology
Cellular and molecular mechanisms of B lymphocyte function; Genetic susceptibility in systemic lupus erythematosus and multiple myeloma; Immunotherapeutics in the treatment of B cell disorders
Ian J. Glomski, Ph.D.
Assistant Professor of Microbiology
Elucidating the molecular mechanisms of B. anthracis pathogenesis; detection and prevention of anthrax.
Joanna B. Goldberg, Ph.D.
Professor of Microbiology
Mechanisms of Bacterial Pathogenesis
Young S. Hahn, Ph.D.
Associate Professor of Microbiology
Immune Suppression by Hepatitis C Virus

Marie-Louise Hammarskjold, M.D., Ph.D.
Professor of Microbiology
Post Transcriptional Gene Regulation and the Molecular Biology of Human Retroviruses
Ulrike M. Lorenz, Ph.D.
Associate Professor of Microbiology
Involvement of the protein tyrosine phosphatase SHP-1 in signal transduction pathways
Marcia J. McDuffie, M.D.
Professor of Microbiology
Genetic analysis of autoimmunity
David W. Mullins, Ph.D.
Assistant Professor of Microbiology
Immunotherapy; Tumor Immunology
Sarah (Sally) J. Parsons, Ph.D.
Professor of Microbiology
Molecular mechanisms of Src family tyrosine kinases in mitogenesis, tumorigenesis, and neuronal activity.
Kodi S. Ravichandran, B.V.Sc., Ph.D.
Professor of Microbiology
Intracecellular signaling in lymphocytes and phagocytes
David M. Rekosh, Ph.D.
Professor of Microbiology
Human Immunodeficiency; Virus Gene Expression

Joint Faculty
Thomas J. Braciale, M.D., Ph.D. Professor of Pathology T Lymphocyte Responses To Virus Infection Michael G. Brown, Ph.D. Associate Professor of Medicine NK Cells and Viral Immunity Timothy N. Bullock, Ph.D. Assistant Professor of Pathology Generation of vaccines to tumors Shu-Man Fu, M.D., Ph.D. Professor and Division Chief of Medicine Human Lymphocyte Biology and Autoimmunity Dean H. Kedes, M.D., Ph.D. Associate Professor of Medicine Human Herpes virus Associated with Kaposi's Sarcoma Shyr-Te Ju, Ph.D. Professor of Medicine Regulatory T Cells and Multi-Organ Autoimmune Disease	Barbara J. Mann, Ph.D. Associate Professor of Medicine Pathogenicity of Francisella tularensis and the human parasite Entamoeba histolytica, vaccines Borna Mehrad, M.D. Associate Professor of Medicine Pulmonary anti-microbial host defense William A. Petri, Jr., M.D., Ph.D. Professor and Division Chief of Medicine Molecular Mechanisms of Pathogenesis of Parasitic Infection Thomas A. Platts-Mills, M.D., Ph.D. Professor of Medicine Common Allergic Diseases Kenneth S. Tung, M.D. Professor of Pathology Tolerance and Autoimmunity: My laboratory explores the fundamental mechanisms of prevention and induction of autoimmune diseases of clinical relevance.

Joint Faculty

Thomas J. Braciale, M.D., Ph.D.
Professor of Pathology
T Lymphocyte Responses To Virus Infection
Michael G. Brown, Ph.D.
Associate Professor of Medicine
NK Cells and Viral Immunity
Timothy N. Bullock, Ph.D.
Assistant Professor of Pathology
Generation of vaccines to tumors
Shu-Man Fu, M.D., Ph.D.
Professor and Division Chief of Medicine
Human Lymphocyte Biology and Autoimmunity
Dean H. Kedes, M.D., Ph.D.
Associate Professor of Medicine
Human Herpes virus Associated with Kaposi's Sarcoma
Shyr-Te Ju, Ph.D.
Professor of Medicine
Regulatory T Cells and Multi-Organ Autoimmune Disease

Barbara J. Mann, Ph.D.
Associate Professor of Medicine
Pathogenicity of Francisella tularensis and the human parasite Entamoeba histolytica, vaccines
Borna Mehrad, M.D.
Associate Professor of Medicine
Pulmonary anti-microbial host defense
William A. Petri, Jr., M.D., Ph.D.
Professor and Division Chief of Medicine
Molecular Mechanisms of Pathogenesis of Parasitic Infection
Thomas A. Platts-Mills, M.D., Ph.D.
Professor of Medicine
Common Allergic Diseases
Kenneth S. Tung, M.D.
Professor of Pathology
Tolerance and Autoimmunity: My laboratory explores the fundamental mechanisms of prevention and induction of autoimmune diseases of clinical relevance.

Department of Microbiology

Department of Microbiology

PO Box 800734

Charlottesville, VA 22908

434-924-5111

fax: 434-982-1071

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Last modified on December 9, 2008