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Kevin  C.  Hazen
Degree(s): Ph.D.
Graduate School: Montana State University
Primary Appointment: Professor of Pathology, Clinical Microbiology
Research Interests:
Fungal pathogenesis. Fungal surface proteins and hydrophobicity.

Email Address: kch7y@virginia.edu
Biomedical Sciences Graduate Program(s)
  • Microbiology, Immunology and Infectious Diseases
  • Molecular Medicine
    • Research Description

    Fungal pathogenesis. Fungal surface proteins and hydrophobicity. My laboratory is concerned with the biochemistry and molecular biology of surface hydrophobic protein expression of medically important fungi, especially Candida. We are also interested in characterizing the role and regulation of surface protein glycosylation as it affects surface hydrophobins (hydrophobic adhesins) interactions with host and prosthetic surfaces. The role of surface hydrophobic proteins in tissue specific adhesion by Candida sp. is also under investigation. Biochemical, molecular genetics, biophysical and histological methods are used in our studies.

    Selected Publications
  • Masuoka J, KC Hazen. 2006. Effect of monosaccharide composition, and glycosidic linkage position and anomericity on electrophoretic mobility of labeled oligosaccharides. Electrophoresis 27: 365-372.
  • Singleton DR, J Masuoka, KC Hazen. 2005. Surface hydrophobicity changes of two C. albicans serotype B mnn4 $B&$ (B mutants. Eukaryotic Cell. 4: 639-648.
  • Masuoka J, KC Hazen. 2004. Cell wall mannan and cell surface hydrophobicity in Candida albicans serotype A and B strains. Infect. Immun. 72(11): 6230-6236
  • Singleton DR, KC Hazen. 2004. Differential surface localization and temperature-dependent expression of the Candida albicans CSH1 protein. Microbiology 150: 275-282.
  • PubMed Listings for this Faculty Member
    • Intranet Profile
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    Contact Information
      Office Address: PO Box 800904, MR-5, 3129, 
      Office Phone: +1 434-924-8067, +1 434-924-8061
      Fax Phone: +1 434-924-2151
      Home Phone: +1 434-293-3660
      Mobile Phone: +1 434-964-6285

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