Neutrophilic Myelocyte
Bone marrow aspirate, Wright-Giemsa stain, 1000x
Description:
The neutrophilic myelocyte has a broad range of appearances when viewed by light microscopy on a Wright-Giemsa stain. The earliest stage is characterized by the appearance of fine, pink (neutrophilic) granules (secondary granules) in the Golgi area, and as a result this area appears brighter. This stage has been referred to as the "dawn of neutrophilia". At this early stage, most of the granules are still primary granules, most of the cytoplasm is still blue, and nucleoli are still visible, but the nuclear chromatin is more coarse and is starting to clump. From this stage the maturation progresses to a mature neutrophilic myelocyte with the cytoplasm being all pink in appearance, and the primary granules having been completely replaced with neutrophilic or secondary granules. The size of a mature myelocyte is smaller than a promyelocyte, the nuclear:cytoplasmic ratio is decreased, the nuclear chromatin is clumped and nucleoli are not seen.
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Charles
E.
Hess,
M.D.,FACP [more information]
Professor of Internal Medicine
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