Pincer Cell
(Mushroom Cell)
Peripheral blood smear, Wright-Giemsa stain, 1000x
Description:
The red cell has a mushroom appearance and lacks central palor.
Pathobiology:
Due to a deficiency of band 3 membrane skeletal proteins.
Differential diagnosis:
- Hereditary spherocytosis due to band 3 membrane protein abnormalities
- Dyserythropoiesis- the range of poikilocytosis seen in the various dyserythropoietic disorders is quite broad.
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Charles
E.
Hess,
M.D.,FACP [more information]
Professor of Internal Medicine
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