Eosinophilic Myelocyte
Bone marrow aspirate smear, Wright-Giemsa stain, 1000x
Description:
The earliest stage of eosinophilic development identifiable by light microscopy on a Wright-Giemsa stain of a bone marrow aspirate is the eosinophilic myelocyte, and is characterized by the appearance of coarse yellowish-red granules in the Golgi area. At this early stage, most of the cytoplasmic granules are still primary granules and most of the cytoplasm is still blue (basophilic). The nucleus is round or oval, the nuclear chromatin is more coarse than in a promyelocyte, and nucleoli often are still visible. From this stage, further maturation occurs until all the cytoplasm is pink (acidophilic), with large eosinophilic granules dispersed throughout, the nucleus remains round or oval, the chromatin is clumped, and nucleoli are not seen (mature eosinophilic myelocyte).
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Charles
E.
Hess,
M.D.,FACP [more information]
Professor of Internal Medicine
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