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Research Interests: A major focus of his research is the investigation of the efficacy of metal stents in both benign and malignant diseases, for which his dynamic team is actively involved in both animal and human studies at the cutting edge of interventional endoscopy. Thanks to his vision, novel diagnostic techniques such as choledochoscopy and confocal imaging have been added to our arsenal to better diagnose and reduce the mortality associated with pancreatico-biliary cancers. Dr Kahaleh is also the Principal-Investigator of a Multicenter study analyzing "Photodynamic Therapy for Unresectable Cholangiocarcinoma", a therapy using laser therapy under direct visualization, for which he has received a research grant from the UVA Cancer Center. Selected Publications: Shami VM, Kahaleh M. Endoscopic Ultrasonography (EUS)-Guided Access and Therapy of Pancreatico-Biliary Disorders: EUS-Guided Cholangio and Pancreatic Drainage.Gastrointest Endosc Clin N Am. 2007;17(3):581-93. Shami VM, Talrejan JP, Mahajan A, Phillips MS, Yeaton P, Kahaleh M. EUS-Guided Drainage of Bilomas: a New Alternative? Gastrointest Endosc. 2008;67:136-40. Kahaleh M, Mishra R, Shami VM, Northup PG, Berg CL, et al. Unresectable Cholangiocarcinoma: Comparison of Survival in BiliaryStenting Alone Versus Stenting With Photodynamic Therapy. Clin Gastroenterol Hepatol 2008;6:290-297. Phillips MS, Gosain S, Bonatti H, Friel CM, Ellen K, Northup PG, Kahaleh M. Enteral Stents for Malignancy: A Report of 46 Consecutive Cases over 10 years, with Critical Review of Complications. J of Gastrointestinal Surg 2008;12:2045-50. Talreja JP, Shami VM, Ku J, Morris TD, Ellen K, Kahaleh M.Transenteric drainage of pancreatic-fluid collections with fully covered self-expanding metallic stents (with video).Gastrointest Endosc. 2008 Dec;68:1199-203. Sauer B, Talreja J, Ellen K, Ku J, Shami VM, Kahaleh M.Temporary placement of a fully covered self-expandable metal stent in the pancreatic duct for management of symptomatic refractory chronic pancreatitis: preliminary data (with videos).Gastrointest Endosc. 2008 Dec;68:1173-8. Mahajan A, Ho HC, Behm B, Phillips MS, Shami VM, Ellen K, Rehan M, Schmitt TM, Kahaleh M.Temporary Placement of Fully Covered Self-Expandable Metal Stents (CSEMS) in Benign Biliary Strictures: Mid term evaluation (with Video). Gastrointest Endosc 2009;70:303-9 Behm BW, Brock A, Clarke BW, Ellen K, Northup PG, Kahaleh M. Treatment of Biliary Strictures Secondary to Chronic Pancreatitis. Endoscopy 2009;41:547-51. Maranki J, Hernandez AJ, Arlan B, Jaffan AA, Angle JF,.Shami VM, Kahaleh M. Interventional EUS-Guided Cholangiography (IEUC): Long Term Experience of an Emerging Alternative to Percutaneous Transhepatic Cholangiography (PTC) with Video. Endoscopy 2009;41:532-8. Wang AY, Ellen K, Berg CL, Schmitt TM, Kahaleh M. Fully covered self-expandable metallic stents in the management of complex biliary leaks: preliminary data - a case series. Endoscopy. 2009;41:781-6. |
