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Research Interest: Clinical Approaches to Inflammatory Bowel Disease (Crohn's Disease and Ulcerative Colitis) The goal of the clinical inflammatory bowel disease clinical group is to advance the understanding of the causes, treatment and personal impact of inflammatory bowel diseases. This is done in collaboration with basic scientists and outcomes researchers. Selected Publications: Comerford L, Bickston SJ. Treatment of Luminal and Fistulizing Crohn's Disease with Infliximab. Gastroenterology Clinics of North America , 2004 Jun;33(2):387-406 Bickston SJ, Comerford L, Cominelli F. Future therapies for inflammatory bowel disease. Current Gastroenterology Reports 2003 Dec;5(6):518-23 Bickston SJ. Keeping the M in Mind: Recombinant Human GMCSF in Crohn’s Disease. Inflammatory Bowel Diseases March 2003.9 (2); 132 Bickston SJ, Cominelli F. Optimal Dosing of 5-Aminosalicylic Acid: Five decades of choosing between politicians. Clinical Gastroenterology and Hepatology 2003;1:3-5 Bickston SJ “When to Eat Dirt” Mycophenolate mofetil: lack of efficacy in chronic active inflammatory bowel disease (Review in Selected Summaries). Inflammatory Bowel Diseases 2000: 06(4):333: Bickston SJ, Cominelli FC. IL-10: Lessons in Biologic Therapy (Editorial) Gastroenterology 2000 Dec;119(6):1781-3. Valle E, Gross M, Bickston SJ. Infliximab. Expert Opinions on Pharmacotherapy . AshleyPublications Ltd., London. 2(6):1015-25, 2001 Bickston SJ, Lichtenstein GR, Arseneau KO, Cohen RB, Cominelli F. The relationship between infliximab treatment and lymphoma in Crohn’s disease.Gastroenterology 117(6):1433-7, 1999 Dec Pizarro TT, Michie MH, Bentz M, Woraratanadharm J, Smith MF, Foley E, Moskaluk CA, Bickston, SJ, Cominelli F. IL-18, a novel immunoregulatory cytokine, is up-regulated in Crohn’s disease: Expression and localization in intestinal mucosal cells. Journal of Immunology 162: 6829-35; 1999. Bickston SJ, Cominelli F. Crohn’s Disease treatment at the turn of the century: New steroids and beyond. New England Journal of Medicine 339:401-2;1998. (Editorial) |
