University of Virginia Health System

Paul  N.  Adler,  Ph.D. Planar signaling, polarity and morphogenesis. David  T.  Auble,  Ph.D. Molecular Mechanisms of Transcription Initiation and DNA Repair Gary  Balian,  Ph.D. Targeted delivery to cells and tissues Paula  Q.  Barrett,  Ph.D. Regulation of low-voltage activated T-type Ca2+ channel activity by kinases and heterotrimeric G-proteins and their roles in physiological responses. Douglas  A.  Bayliss,  Ph.D. Mechanisms of Neuromodulation in Central Neurons Timothy  P.  Bender,  Ph. D. Regulation of gene expression during lymphocyte development Ann  L.  Beyer,  Ph.D. Ribosomal RNA transcription & processing George  S.  Bloom,  Ph.D. Cellular Morphogenesis and Motility; Cell Biology of Alzheimer's Disease Amy  H.  Bouton,  Ph.D. Signaling Pathways that Regulate Tumor Growth, Metastasis, and Response to Anticancer Agents; Adhesion Signaling In Macrophages; Bacteria-Host Cell Interactions David  L.  Brautigan,  Ph.D. Protein Ser/Thr Phosphatases in Cell Signaling and Cell Cycle Jay  C.  Brown,  Ph.D. Structure and Assembly of the Herpes Simplex Virus Capsid. Daniel  J.  Burke,  Ph.D. Regulation of mitosis John  H.  Bushweller,  Ph.D. Structural and Functional Basis for Oncogenesis; Targeted Drug Development; Structural Studies of Membrane Proteins James  E.  Casanova,  Ph.D. Membrane Trafficking and Salmonella Pathogenesis J.  David  Castle,  Ph.D. Regulation of Membrane Recycling and Protein Secretion Carl  E.  Creutz,  Ph.D. Calcium-dependent, Membrane-binding Proteins and Mechanisms of Exocytosis Claire  R.  Cronmiller,  Ph.D. Genetic Regulation of Morphogenesis and Reproduction in Drosophila Zygmunt  S.  Derewenda,  Ph.D. Mechanisms of Intracellular Signal Transduction; X-ray Crystallography Douglas  W.  DeSimone,  Ph.D. Cell Adhesion and Adhesion-Dependent Cell Signaling in Vertebrate Morphogenesis Anindya  Dutta,  M.D., Ph.D. DNA Replication and Genomic Instability in Cancer Cells Edward  H.  Egelman,  Ph.D. Structure and Function of Macromolecular Complexes Using Electron Microscopy Daniel  A.  Engel,  Ph.D. Transcriptional Regulation in Cancer Cells Victor  H.  Engelhard,  Ph.D. Immune responses to tumors and immunotherapy / Impact of self-tolerance on anti-tumor immunity / Processing and presentation of MHC-restricted antigens James  C.  Garrison,  II,  Ph.D. Role of the G protein &alpha and &beta&gamma Subunits in Cell Signaling Adrian  R.L.  Gear,  D.Phil. Blood-platelet function; Cardiovascular disease; Inflammation Joanna  B.  Goldberg,  Ph.D. Mechanisms of Bacterial Pathogenesis Patrick  A.  Grant,  Ph.D. Transcription; Chromatin Modifications Carla  B.  Green,  Ph.D. Transcriptional and Post-transcriptional Regulation of Circadian Clocks Barry  M.  Gumbiner,  Ph.D. Cell Adhesion and Morphogenesis; Wnt Signaling; Cadherins and Catenins; Development and Cancer Young  S.  Hahn,  Ph.D. Immune Suppression by Hepatitis C Virus Joyce  L.  Hamlin,  Ph.D. Control of Mammalian Chromosomal DNA Replication, and DNA Damage, Repair and Genetic Instability in Cancer Marie-Louise  Hammarskjold,  M.D., Ph.D. Post Transcriptional Gene Regulation and the Molecular Biology of Human Retroviruses Jay  Hirsh,  Ph.D. Molecular genetics; development and function of neurotransmitter-synthesizing neurons in Drosophila Alan  F. "Rick"  Horwitz,  Ph.D. Synapse Formation and Cell Migration in Normal and Pathobiology-Adhesion, Signaling, Imaging and Proteomics Dean  H.  Kedes,  M.D., Ph.D. Human Herpes virus Associated with Kaposi's Sarcoma Raymond  E.  Keller,  Ph.D. Cellular and molecular mechanisms of morphogenesis Sepideh  Khorasanizadeh,  Ph.D. Biophysical Characterization of Epigenetic Signaling Keith  G.  Kozminski,  Ph.D. Regulation of Polarized Morphogenesis by Small G Proteins Deborah  A.  Lannigan,  Ph.D. Kinases, Drugs and Breast Cancer Gordon  W.  Laurie,  Ph.D. Epithelial Renewal, Viability and Secretion Jeh-Ping (Serena)  Liu,  Ph.D. Spinal Cord Development and Motor Neuron Differentiation Ulrike  M.  Lorenz,  Ph.D. Involvement of the protein tyrosine phosphatase SHP-1 in signal transduction pathways Kevin  R.  Lynch,  Ph.D. Molecular Pharmacology of Lysophospholipid Mediators Ian  G.  Macara,  Ph.D. Mechanisms of Cell Polarity Establishment and Nuclear Transport Mani  S.  Mahadevan,  M.D. Molecular Mechanisms of Myotonic Muscular Dystrophy Marty  W.  Mayo,  Ph.D. Transcriptional Regulation by NFKB Wladek  Minor,  Ph.D. Structure-Function Relationships in Proteins; Structural Genomics; Bioinformatics Raghavendra  G.  Mirmira,  M.D., Ph.D. Transcriptional Regulation of B-cell Differentiation Robert  K.  Nakamoto,  Ph.D. Structure-Function of Active Transporters Gary  K.  Owens,  Ph.D. Molecular Control of Smooth Muscle Cell Differentiation J.  Thomas  Parsons,  Ph.D. Adhesion Signaling in Normal, Cardiovascular and Cancer Cells Sarah (Sally)  J.  Parsons,  Ph.D. Molecular mechanisms of Src family tyrosine kinases in mitogenesis, tumorigenesis, and neuronal activity. Bryce  M.  Paschal,  Ph.D. Nuclear Transport, Signaling, and Cancer William  R.  Pearson,  Ph.D. Glutathione S-Transferases; Protein Evolution; Computational Biology Lucy  F.  Pemberton,  Ph.D. Nuclear Transport in Chromatin Assembly and Transcriptional Regulation K.  Kevin  Pfister,  Ph.D. Structure, Function, and Regulation of Cytoplasmic Dynein: Its Role in Intracellular Microtubule-based Transport, Membrane Bounded Organelle Trafficking, Axonal Transport and Mitosis Fraydoon  Rastinejad,  Ph.D. Analysis of Nuclear Receptor Complexes with DNA and Ligands Kodi  S.  Ravichandran,  B.V.Sc., Ph.D. Intracecellular signaling in lymphocytes and phagocytes David  M.  Rekosh,  Ph.D. Human Immunodeficiency; Virus Gene Expression Dorothy  A.  Schafer,  Ph.D. Mechanisms of actin assembly during cell migration and membrane traffic Martin  A.  Schwartz,  Ph.D. Integrin Signaling and Its Relevance to Mechanotransduction, Cancer and Vascular Disease Heidi  Scrable,  Ph.D. Novel Strategies to Model Human Diseases in the Laboratory Mouse Zhifeng  Shao,  Ph.D. Molecular Imaging and Single Molecule Biophysics Margaret  A.  Shupnik,  Ph.D. Hypothalamic peptide and steroid regulation of pituitary gene transcription; Estrogen action in neuroendocrine and reproductive tissues; Estrogen action in breast cancer Jeffrey  S.  Smith,  Ph.D. Transcriptional Silencing and Aging in Yeast M.  Mitchell  Smith,  Ph.D. Functional Genomics of Histones, Chromatin, and Protein Acetylation Signaling in Cancer and the Cell Cycle Avril  V.  Somlyo,  Ph.D. Signaling pathways that regulate contractility in smooth muscle tissues and migrating cells in normal and disease states such an coronary artery disease, asthma and hypertension. Structure function studies of the intercalated disk in the heart. P.  Todd  Stukenberg,  Ph.D. Mechanisms of mitotic regulation Ann  E.  Sutherland,  Ph.D. Cell Matrix Interactions In Mouse Development Lukas  K.  Tamm,  Ph.D. Biomembrane Structure and Function; Membrane Fusion in Viral Cell Entry and Exocytosis; Lipid-Protein Interactions Michael  P.  Timko,  Ph.D. Gene regulation during host-parasite interaction Michael  J.  Weber,  Ph.D. Signal Transducing Kinases in Cancer Judith  M.  White,  Ph.D. Virus Entry Into Cells; ADAMs in Early Development Michael  C.  Wiener,  Ph.D. Structural biology (esp. crystallography) of integral membrane proteins; TonB-dependent active transport across the bacterial outer membrane; cancer-related membrane proteins; crystallization methods development Mary  K.  Worden,  Ph.D. Hormonal Modulation of Neuromuscular Function W.  Michael  Wormington,  Ph.D. Post-Transcriptional Regulation of Gene Expression During Oogenesis and Early Development David  Wotton,  Ph.D. Regulation of Gene Expression and Development by Transcriptional Repressors J.  Julius  Zhu,  Ph.D. Mechanisms of Synaptic Plasticity and Mental Retardation