Your search found 171 trials
UVa Health System, Division of Endocrinology, seeks Healthy Women ages 20 and older who have just had a baby or are about to have a baby for a research study. The research study begins after delivery. The purpose of the study is to under...
Department: Internal Medicine
Primary Investigator: Brown Sue, A

UVa Health System, Cancer Center seeks participants with cervical cancer for a research study. The purpose of the study is to determine if combining Tirapazamine (TPZ) with Cisplatin during radiation therapy increases progression-free s...
Primary Investigator: Modesitt Susan, C

UVa Health System, Department of Neurology is looking for men and women ages 18 through 55 with relapsing-remitting Multiple Sclerosis (MS) with a documented relapse in the past year or 2 relapses in the past 2 years, for a research study. ...
Category: , Neurology
Department: Neurology
Primary Investigator: Goldman Myla, D

UVA Health System seeks adults with Parkinson's Disease for a research study. The purpose of the study is to test an investigational device that will deliver Deep Brain Stimulation in an effort to treat the symptoms of Parkinsons Disease....
Category: , Neurology , Neurosurgery
Department: Neurological Surgery
Primary Investigator: Elias William (Jeff), J

UVa Health System, Department of Orthopaedic Surgery seeks adults with painful osteoarthritis of the shoulder (glenohumeral) joint for a research study. The purpose of the study is see if an experimental injection called ORTHOVISC is s...
Department: Orthopaedic Surgery
Primary Investigator: Diduch David, R

Polycystic kidney disease(PKD) is a disease of the kidneys and other organs, which is inherited in several different forms. The disease leads to end stage renal disease (ESRD) in many patients. ESRD can be treated by dialysis (an artifici...
Category: , Nephrology (Kidney)
Department: Internal Medicine
Primary Investigator: Bolton W. Kline,

Do you like to drink Beer? Volunteers ages 21 to 45 are needed for a new investigational medication study examining cravings for alcohol. Participants will take two 5-day periods of an investigational medication (Strattera®) and make 5 ou...
Category: , Psychiatry/Psychology
Primary Investigator: Haughey Heather,

UVa Health System, Neurology Department, F.E. Dreifuss Comprehensive Epilepsy Program seeks Women, Men, ages 16-70 with partial seizures and are taking 1 or 2 anti-epileptic drugs for research study. The purpose of the study is to see i...
Category: , Neurology
Department: Neurology
Primary Investigator: Fountain Nathan, B

A Multicenter Prospective Study of Neurological Recovery as a Factor of Time to Decompression of Cervical Spinal Cord Injuries with Spinal Cord Compression (STACSIS) The primary goal of this clinical trial is to determine whether early (...
Category: , Neurosurgery
Department: Neurological Surgery
Primary Investigator: Shaffrey Chris,

UVa Health System, seeks those with Cystic Fibrosis (CF) ages 5 years and older for research study called TIGER-1. The purpose of the Tiger-1 study is to evaluate the safety and effectiveness of an investigational compound for mild CF lu...
Department: Pediatrics
Primary Investigator: Froh Deborah, K

The purpose of the study is to evaluate whether creatine is more effective than placebo in slowing clinical worsening in patients with Parkinsons Disease. The study involves taking creatine or placebo twice a day, blood draws, assessment...
Category: , Neurology
Department: Neurology
Primary Investigator: Wooten George, F

UVa Health System, Department of Urology seeks Men and Women ages 18-80 with incontinence due to neurogenic overactive bladder for a research study. The purpose of the study is to investigate the safety and effectiveness of BOTOX® for th...
Category: , Urology
Department: Urology
Primary Investigator: Steers William, D

Glioblastoma multiforme (GBM) is a type of brain tumor that is cancerous. The usual treatments include surgery, radiation therapy, and chemotherapy. Unfortunately, these tumors are very difficult to treat and often recur within several mon...
Department: Neurology
Primary Investigator: Schiff David,

The purpose of the study is to learn more about how much people smoke and ways people try to stop smoking. People who are interested in exploring different ways to help themselves stop smoking may be eligible to participate in this study. ...
Category: , Cancer (Oncology) , Surgery
Department: Surgery
Primary Investigator: Kozower Benjamin,

UVA Health System, Cancer Center, seeks adults with breast cancer for a research study. The type of breast cancer being studied is estrogen-negative, progesterone-negative, and HER-2 negative breast cancer that has either returned or the c...
Department: Internal Medicine
Primary Investigator: Fracasso Paula, M

Health System, Human Immune Therapy Center, seeks participants with melanoma for a research study. The purpose of this study is to find out what effects drugs CCI-779 and bevacizumab have on participants and melanoma. CCI-779 is an expe...
Department: Surgery
Primary Investigator: Slingluff Craig, L

Do you drink too much? Do you want to quit drinking or at least reduce the amount you drink? If you are 18 to 64 years of age, you may qualify to participate in research study to test the effects of an investigational medication for t...

For adults, age 50+, with wet AMD, who have not received prior AMD treatment. Studies evaluate the safety and effectiveness of investigational medication to see if it helps slow or stop progression of wet-AMD related vision loss. Participa...
Category: , Ophthalmology
Department: Ophthalmology
Primary Investigator: Conway Brian, P

UVa Health System seeks adults with Glioblastoma for research study Glioblastoma multiforme (GBM) is a type of malignant brain tumor. The usual treatments include surgery, radiation therapy, and chemotherapy. Unfortunately, these tumor...
Department: Neurology
Primary Investigator: Schiff David,

The Cancer Center at UVa Health System seeks for a research study women who have chosen to undergo surgery that has resulted in the removal of both ovaries. The purpose of this study is to find out what effects zoledronic acid (Zometa...
Primary Investigator: Modesitt Susan, C

The UVA Health System Cancer Center seeks adults with cancer of the head and neck for a research study. Participants in the study will have recurrent or metastatic cancer: that is, the cancer responded to treatment and then recurred or has...
Department: Internal Medicine
Primary Investigator: Thomas Christopher, Y

UVa Health System, Neuro-Oncology Center seeks women and men ages 18 and older with newly diagnosed Glioblastoma Multiforme (GBM) for a research study. The purpose of the study is to evaluate the safety and effectiveness of an investigat...
Department: Neurology
Primary Investigator: Schiff David,

UVA Health System, Cancer Center, seeks adults over the age of 18, with chronic myelogenous leukemia in chronic phase (CML-CP) for a research study. The purpose of this research study is to find the best treatment for CML-CP p...
Category: , Cancer (Oncology)
Department: Internal Medicine
Primary Investigator: Douvas Michael, G

UVa Health System, Cancer Center seeks children, adolescents, and young adults aged 1 month through age 29 with De Novo Acute Myeloid Leukemia (AML) for a research study. Researchers are conducting the study to find out if adding an inve...
Department: Pediatrics
Primary Investigator: Dunsmore Kimberly, P

UVa Health System, Cancer Center seeks children, adolescents, and young adults aged 0-21 with low-risk Hodgkins Disease for a research study. Researchers are conducting may result in difficult effects (late effects) later in life. Res...
Department: Pediatrics
Primary Investigator: Dunsmore Kimberly, P

Are you 50 or older and suffering from lack of sexual desire? Dr. Anita Clayton with the UVA Health System Center for Psychiatric Clinical Research is conducting a research study of an investigational drug for symptoms of decreased sexua...
Category: , Psychiatry/Psychology
Department: Psychiatric Medicine
Primary Investigator: Clayton Anita, H

Website advertisement: Title: A Phase III, Randomized, Double-Blind, Placebo-Controlled, Multi-Center Study of the Safety and Efficacy of Libigel® for the Treatment of Hypoactive Sexual Desire Disorder in Surgically Menopausal Women ...

Glioblastoma multiforme (GBM) is a kind of brain tumor. The usual treatments are: surgery, radiation therapy and chemotherapy. Unfortunately, these tumors are resistant to most treatments and rapidly recur within months of treatment. The...
Department: Neurology
Primary Investigator: Schiff David,

UVa Health System seeks adults with Glioblastoma for research study Glioblastoma multiforme (GBM) is a type of malignant brain tumor. The usual treatments include surgery, radiation therapy, and chemotherapy. Unfortunately, glioblastom...
Department: Neurology
Primary Investigator: Schiff David,

Summary: The VITAL- Valve Intervention Treatment Trial. A clinical trial is underway utilizing an investigational device intended to improve the over all health status and quality of life for people living with emphysema. This is a rando...
Category: , Pulmonary/Respiratory
Department: Internal Medicine
Primary Investigator: Truwit Jonathon, D

The Human Immune Therapy Center of the Cancer Center at the University of Virginia Health System invites adults with melanoma to enroll in a research study. The purpose of the study is to test investigational vaccines to see if they are...
Department: Surgery
Primary Investigator: Slingluff Craig, L

UVa Health System, Cancer Center seeks women who have been diagnosed with breast cancer and who have had a lumpectomy for a research study. Studies have shown that giving radiation therapy to the breast after lumpectomy helps keep cance...
Category: , Cancer (Oncology)
Department: Radiation Oncology
Primary Investigator: Read Paul, W

UVa Health System Department of Surgery seeks adults with lung cancer who are scheduled to have surgery for treatment of their condition for research study. The purpose of the study is to compare the results of removal of a small portion ...
Category: , Cancer (Oncology) , Surgery
Department: Surgery
Primary Investigator: Jones David, R

The Cancer Center at the University of Virginia invites women with advanced stage or recurrent endometrial cancer to enroll in a clinical study. This type of cancer is typically treated with chemotherapy with the three-drug combination ...
Primary Investigator: Modesitt Susan, C

UVa Health System, Cancer Center seeks participants with ovarian or peritoneal primary cancer for a research study. The purpose of this study is is to compare a new chemotherapy combination of carboplatin, paclitaxel and Bevacizumab to...
Primary Investigator: Modesitt Susan, C

The Cancer Center at the University of Virginia Health System invites patients who are younger than 21 years old and diagnosed with osteosarcoma to participate in a research study. The purpose of this study is to determine how best to ...
Department: Pediatrics
Primary Investigator: Dunsmore Kimberly, P

UVa Health System, Department of Surgery, Transplant Division seeks adults ages 18 and up that are listed for a liver transplant for a research study. The purpose of the study is to see if an experimental drug is safe and effective in pr...
Category: , Surgery , Hepatology
Department: Surgery
Primary Investigator: Pruett Timothy,

The University of Virginia is participating in the Crescendo study, an international study investigating the safety and efficacy of the investigational drug rimonabant, in combating symptoms of metabolic syndrome. This study medicatio...
Category: , Endocrinology
Department: Internal Medicine
Primary Investigator: McCall Anthony,

UVa Health System, Department of Radiology, seeks men and women 18 years or older with a new blood clot in an artery or by-pass graft in the leg, for a research study. The purpose of the study is to find out if an experimental drug, Plas...
Category: , Cardiology/Vascular
Department: Radiology
Primary Investigator: Matsumoto Alan, H

Volunteers 18 and older are needed for a study on Bipolar I Depression. Dr. Anita Clayton with the UVa Health System, Center for Psychiatric Clinical Research, is conducting a study of an investigational drug for bipolar depression compared...
Category: , Psychiatry/Psychology
Department: Psychiatric Medicine
Primary Investigator: Clayton Anita, H

Dr. Christine Houlihan of the University of Virginia is conducting a clinical study to look at how childrens bones grow and mature when they have Cerebral Palsy. This information will be compared to growth in children that do not have Cer...
Category: , Pediatrics
Department: Pediatrics
Primary Investigator: Houlihan Christine, M

The purpose of the study is to find out whether regular exercise helps people with asthma control their disease and improve actual lung function. The study involves a breathing test (spirometry), a body fat and muscle measurement, blood te...

This study is being conducted along with the Shriner's Hospital System to collect information on what services, treatments, and supports that are responsive to the needs of children with cerebral palsy and their families. Who can be in ...
Category: , Pediatrics
Department: Orthopaedic Surgery
Primary Investigator: Abel Mark, F

UVa Health System, School of Medicine, Department of Physical Medicine and Rehabilitation seeks Senior Adults ages 65 and above with both independent and assisted daily living functioning, for research study. The purpose of the study is ...
Primary Investigator: Kerrigan D. Casey,

Adults ages 45 or older with a history of heart disease, vascular disease or abnormal cholesterol levels are needed for a study looking at the effect of adding extended release niacin to simvastatin (Zocor®). Researchers what to know if th...
Category: , Cardiology/Vascular
Department: Internal Medicine
Primary Investigator: Simpson Allan,

Do you have Asthma? Volunteers (ages 18 to 40 years old) are needed for a study about asthma and the common cold. This study is being conducted by physicians in the Asthma and Allergic Diseases Center at the UVA Health System. The goal i...

The University of Virginia Health System Cancer Center seeks adults with multiple myeloma for a research study. The purpose of this research is to study an investigational medication called perifosine and to see if the use of perifosine is...
Department: Internal Medicine
Primary Investigator: Densmore John, J

UVa Health System, Pulmonary Division, seeks Women, Men, ages 18 and older with Pulmonary Arterial Hypertension for research study. The purpose of the study is to find out what effects (good and bad) ambrisentan, a drug not yet approved ...
Category: , Pulmonary/Respiratory
Department: Internal Medicine
Primary Investigator: Boedefeld Robyn, L

Girls ages 8 to 18, who are not taking hormonal medications, are needed for studies of reproductive hormone changes during adolescence. Some studies involve a single blood sample or an overnight admission in the General Clinical Research C...

Girls ages 8 to 18, who are not taking hormonal medications, are needed for studies of reproductive hormone changes during adolescence. Some studies involve a single blood sample or an overnight admission in the General Clinical Research C...
Department: Internal Medicine
Primary Investigator: Marshall John, C

Girls ages 8 to 18, who are not taking hormonal medications, are needed for studies of reproductive hormone changes during adolescence. Some studies involve a single blood sample or an overnight admission in the General Clinical Research C...
Department: Internal Medicine
Primary Investigator: Marshall John, C

UNIVERSITY OF VIRGINIA HEALTH SYSTEM IS LOOKING FOR YOUNG PEOPLE TO PARTICIPATE IN A HALF DAY RESEARCH STUDY ON EXERCISE THIS SUMMER. ALL PARTICIPANTS WHO COMPLETE THE HALF DAY STUDY WILL RECEIVE $100 YOU WOULD HAVE TO: 1. COME TO ...
Department: Internal Medicine
Primary Investigator: Platts-Mills Thomas, A