CURRICULUM VITAE
RICHARD L. GUERRANT, M.D.
WORK
Founder, Director, Center for Global Health
Division of Infection Diseases and International Health
EDUCATION
B.S. 1961-1964 Davidson College, Davidson, North Carolina
M.D. 1964-1968 University of Virginia School of Medicine,
Charlottesville, Virginia
PROFESSIONAL CAREER
1968-69 Intern, Harvard Medical Service, Boston City Hospital (Dr. Maxwell Finland), Boston, Massachusetts
1969-70 Assistant Resident Physician, Harvard Medical Service, Boston City Hospital (Dr. James Jandl), Boston, Massachusetts
1970-71 Staff Associate, National Institutes of Health, National Institute of Allergy and Infectious Diseases, assigned to Cholera Research Laboratory, Dacca, Bangladesh (Dr. John Seal)
1971-72 Staff Associate, National Institutes of Health, National Institute of Allergy and Infectious Diseases, assigned to Gerontology Research Building and Johns Hopkins University School of Medicine (Drs. John Seal and Charles C.J. Carpenter), Baltimore, Maryland
1972-73 Chief Resident and Instructor in Medicine, University of Virginia Hospital (Dr. Edward W. Hook), Charlottesville, Virginia
1973-74 Fellow in Medicine (Infectious Diseases, Dr. Gerald L. Mandell), University of Virginia Hospital, Charlottesville, Virginia
1974-76 Assistant Professor of Medicine, University of Virginia School of Medicine, Charlottesville, Virginia
1976-81 Associate Professor of Medicine (1978, with tenure), University of Virginia School of Medicine, Charlottesville, Virginia
1978- Head, Division of Geographic and International Medicine, University of Virginia School of Medicine, Charlottesville, Virginia
1981- Professor of Medicine, University of Virginia School of Medicine, Charlottesville, Virginia
1991- Thomas H. Hunter, Professor of International Medicine, University of Virginia School of Medicine in Charlottesville
1994- Director, Office of International Health and Center for Global Health, University of Virginia School of Medicine, Charlottesville, VA
MILITARY SERVICE
1970-72 Lieutenant Commander, U.S. Public Health Service, National Institutes of Health, Bethesda, Maryland
BOARD CERTIFICATION
American Board of Internal Medicine, 1973
SUBSPECIALITY BOARDS
Infectious Diseases, 1976
PROFESSIONAL SOCIETY MEMBERSHIPS AND HONORS
Fellow of the American College of Physicians
Alpha Omega Alpha
The Raven Society, University of Virginia
Smith, Kline and French Foreign Fellowship (Democratic Republic of the Congo, formerly Zaire), 1967
Albemarle County Medical Society
American Federation for Clinical Research
American Society for Microbiology
George Morris Piersol Teaching and Research Scholar, American College of Physicians, July 1974-June 1977
The John Horsley Memorial Prize for excellence in research, 1974
Southern Society for Clinical Investigation
Society for Experimental Biology and Medicine
Fellow, Infectious Disease Society of America
American Society of Tropical Medicine and Hygiene
American Society for Microbiology Visiting Professorship, LAPP Program, University of Campinas, São Paulo, Brazil, April 1981
American Society for Clinical Investigation, 1981
Fellow of the Royal Society of Tropical Medicine and Hygiene
Member of the Tropical Disease Research Advisory Committee, The Edna McConnell Clark Foundation, 1982-85
Chairman, Division B (Pathogenesis of Bacterial Mycotic and Protozoal Infections), American Society for Microbiology, 1985
Chairman for State of Virginia Partners of the Americas (Virginia:Santa Catarina Partnership), 1985-1987
Veterans Administration Merit Review Board, 1984-87
Medical School Representative on University-Wide Self Study Committee on Research, 1984-85
University Faculty Forum on Scientific Research, 1981-85
Annie Lipscomb Lecture, 1985
Association of American Physicians, 1987
Member of the Technical Advisory Group, Applied Diarrheal Diseases Research Project, Harvard Institute of International Health
Chair, Advisory Committee for students seeking Internships in Medicine (1986-1994)
Electives Committee (member 1986-present)
Department of Medicine Research Day (Chairman 1989-present)
Member of the Scientific Working Group on Case Management, Diarrheal Disease Control Programme, World Health Organization, Geneva (1987-1989)
Member; NIAID/NIH AIDS Clinical Drug Development Committee (1989-1993)
Member, Board of Directors, Project HOPE 1990
Member, U.S. Cholera Panel; US-Japan Cooperative Medical Science Program 1987 present
Chair, U.S. Cholera Panel 1991 2000
Member, NIH AIDS and Related Research Study Section 5, 1993 1997
Recipient Joseph E. Smadel Medal and Lecture, IDSA, 1993
Professor Honoris Causa bestowed by Federal University of Ceará, January 1994
Board of Trustees of the Child Health Foundation, 1995
American Clinical and Climatological Association, 1995
Listed in Best Doctors in America, 1995--present
President-elect, American Society of Tropical Medicine and Hygiene, 1995
Recipient of the Abbott Award, Infectious Diseases Society of America, 1997
Recipient of the University-wide Henderson Inventor of the Year Award, 1997
President, ASTMH, 1996-1997
Recipient of the Emilio Ribas Medal for International Category of the Brazilian Society of Infectious Diseases, 1997
Chair, IDSA International Affairs Committee, 1998-2000
IDSA Nominating Committee, 1998-2001
Elected to Institute of Medicine of the National Academy of Sciences, 2003
Member, IOM Board on Global Health, 2005
Walter Reed Medal, American Society of Tropical Medicine and Hygiene, 2008
EDITORIAL APPOINTMENTS
Editorial Board, Annals of Internal Medicine, 1981-1984
Editorial Board, Infect Immun, 1984-1986
Editorial Board, Reviews of Infectious Diseases, 1989-1992
Editorial Board, Journal of Infectious Diseases, 1992-Present
Editorial Board, Biomedical Journal, 1994-Present
Editorial Board, Emerging Infectious Diseases, 1998-2001
PATENTS
RG-01 Use of Phospholipase Inhibitors in the Therapy of Clostridium difficile Diarrhea. U.S. patent number 4,820,716, issued 1989. April 11, 1989
BM Composition and Methods for the Enrichment and Isolation of Campylobacter pylori and Related Organisms. U.S. patent number 4,923,801, issued 1990.
RG-02 New in vitro Test for Fecal Leukocytes. U.S. patent number 5,124,252, issued June 23, 1992
RG-04 Use of Platelet Activity Factor (PAF) and Cyclooxygenase Inhibitions in the Therapy of Clostridium difficile and Cholera Diarrhea. U.S. patent number 5,436,239, issued July 1, 1995
RG-06 Stable Glutamine Derivatives for Oral and Intravenous Rehydration and Nutrition Therapy. U.S. Patent Number 5,561,111, issued October 1, 1996.
RG-09 Biological production of stable glutamine, poly-glutamine derivative in transgenic organisms and their use for therapeutic purposes. U.S. patent number 6,649,746, issued November 18, 2003
BOOKS
1. Guerrant RL, Editor. Microbial Toxins and Diarrheal Diseases. CIBA Foundation Symposium 112, Pittman, London 1988.
2. Guerrant RL, Editor. Diarrheal Diseases. Bailliere's Clinical Tropical Medicine and Communicable Diseases. Bailliere Tindall, London 1988.
3. Blaser MT, Smith PD, Ravdin JI, Greenberg HB and Guerrant RL, Editors. Infections of the Gastrointestinal Tract. Raven Press, 1995.
4. Guerrant RL, Nations MK, de Souza MA, Editors. At the Edge of Development: Health Crisis in a Transitional Society, Carolina Academic Press, 1996.
5. Guerrant RL, Walker DH and Weller PF, Editors. Tropical Infectious Diseases: Principles, Pathogens, & Practice, Vols. 1 and 2, Churchill Livingstone, Philadelphia, 1999.
6. Guerrant RL, Walker DH and Weller PF, Editors. Essentials of Tropical Infectious Diseases, Churchill Livingston, Philadelphia, 2001.
7. Guerrant RL, Walker DH and Weller PF, Editors. Tropical Infectious Diseases: Principles, Pathogens, & Practice, Second Edition; Vols. 1 and 2, Churchill Livingstone, Philadelphia, 2006.
SCIENTIFIC PUBLICATIONS
1. Langman J, Guerrant RL and Freeman BG. Behavior of neuroepithelial cells during closure of the neural tube. J Comp Neurol 127:399-412, 1966.
2. Guerrant RL, Chen LC and Sharp GWG. Intestinal adenyl-cyclase activity in canine cholera: Correlation with fluid accumulation. J Infect Dis 125:377-381, 1972.
3. Guerrant RL, Chen LC and Rohde JE. Effect of spironolactone on stool electrolyte losses during human cholera. Gut 13:197-200, 1972.
4. Pierce NF, Guerrant RL, Wallace CK and Carpenter CCJ. Recent observations on the pathophysiologic effects of E. coli enterotoxin. In: Symposium on Cholera. Fukumi H and Ohashi M, Editors. U.S.-Japan Cooperative Medical Science Program, Tokyo, 1972.
5. Carpenter CCJ and Guerrant RL. Current understanding of the mechanisms of action of V. cholerae and E. coli enterotoxins. In: Symposium on Cholera. Fukumi H and Ohashi M, Editors. U.S.-Japan Cooperative Medical Science Program, Tokyo, 1972.
6. Guerrant RL and Cash RA. Infectious disease: Treatment of cholera and other diarrheal illnesses. In: Disaster in Bangladesh: Health Crisis in a Developing Nation, Chapter 7. Chen LC, Editor. Oxford University Press, 1973.
7. Singh JG, Starobin OE, Guerrant RL and Manders EK. Reversible atrioventricular block in myxedema. Chest 63:582-585, 1973.
8. Guerrant RL, Ganguly U, Casper AGT, Moore EJ, Pierce NF and Carpenter CCJ. Effect of Escherichia coli on fluid transport across canine small bowel: Mechanism and time-course with enterotoxin and whole bacterial cells. J Clin Invest 52:1707-1714, 1973.
9. Guerrant RL, Carpenter CCJ and Pierce NF. Experimental E. coli diarrhea: Effects of viable bacteria and enterotoxin. Trans Assoc Am Phys 86:111-120, 1973.
10. Chen LC, Guerrant RL, Rohde JE and Casper AGT. Effect of amphotericin B on sodium and water movement across normal and choleratoxin-challenged canine jejunum. Gastroenterology 65:252-258, 1973.
11. Hewlett EL, Guerrant RL, Evans DJ Jr and Greenough III, WB. Toxins of Vibrio cholerae and Escherichia coli stimulate adenyl cyclase in rat fat cells. Nature 249:371-373, 1974.
12. Guerrant RL, Brunton LL, Schnaitman TC, Rebhun LI and Gilman AG. Cyclic adenosine monophosphate and alteration of Chinese hamster ovary cell morphology: A rapid, sensitive, in vitro assay for the enterotoxins of Vibrio cholerae and Escherichia coli. Infect Immun 10:320-327, 1974.
13. Guerrant RL. Characterization and clinical use of the Chinese hamster ovary (CHO) cell assay for enterotoxins and antitoxins. In: Symposium on Cholera. Fukumi H and Ohashi M, Editors. U.S.-Japan Cooperative Medical Science Program, Kyoto, 1974.
14. Guerrant RL and Carpenter CCJ. Diarrheagenic effect of volume expansion: Intestinal fluid secretion without mucosal adenyl cyclase stimulation. Johns Hopkins Med J 136:209-211, 1975.
15. Guerrant RL, Moore RA, Kirschenfeld PM and Sande MA. Role of toxigenic and invasive bacteria in acute diarrhea of childhood. N Engl J Med 293:567-573, 1975.
16. Hook EW and Guerrant RL. Antimicrobial therapy of bacterial endocarditis. In: Infective Endocarditis, Chapter 12. Kaye D, Editor. University Park Press, Philadelphia, 1976.
17. Korzeniowski OM, Moore RA and Guerrant RL. Diarreia com desidratacao nas criancas examinadas no Hospital Infantil em Florianopolis SC: Etiologias potenciais e implacacoes para terapia. Arz Cat Med 5:5-8, 1976.
18. Yousten AA and Guerrant RL. Comparative activities of Bacillus thuringiensis endotoxin, choleratoxin and Escherichia coli enterotoxin. J Invest Pathol 28:395-397, 1976.
19. Guerrant RL, Humphries MK Jr, Butler JE and Jackson RS. Tick-borne oculoglandular tularemia: Case report and review of tick-associated tularemia in Virginia. Arch Intern Med 136(7):811-813, 1976.
20. Strausbaugh LJ, Bolton WK, Dilworth JA, Guerrant RL and Sande MA. Comparative pharmacology of josamycin and erythromycin stearate. Antimicrob Agents Chemother 10:450-456, 1976.
21. Guerrant RL, Dickens MD, Wenzel RP and Kapikian AZ. Toxigenic bacterial diarrhea: Nursery outbreak involving multiple bacterial strains. J Pediatr 89:885-891, 1976.
22. Hook EW and Guerrant RL. Salmonella infections. In: Harrison's Principles of Internal Medicine, 8th Edition, pp 839-847. McGraw-Hill Book Company, New York, 1976.
23. Guerrant RL and Brunton LL. Characterization of the Chinese hamster ovary cell assay for the enterotoxins of Vibrio cholerae and Escherichia coli and for antitoxins: Differential inhibition by gangliosides, specific antisera and toxoid. J Infect Dis 135:720-728, 1977.
24. Guerrant RL, Strausbaugh LJ, Wenzel RP, Hamory BH and Sande MA. Nosocomial bloodstream infections caused by gentamicin-resistant gram negative bacilli. Am J Med 62-894-901, 1977.
25. Nozawa RT and Guerrant RL. Fibrin adherent CHO cell behavior in response to chelators and enterotoxin. Exper Cell Res 107:25-30, 1977.
26. Rosenberg ML, Koplan JP, Wachsmuth IK, Wells JG, Gangarosa EJ, Guerrant RL and Sack DA. Epidemic diarrhea at Crater Lake: A large, waterborne outbreak caused by enterotoxigenic Escherichia coli. Ann Intern Med 86:714-718, 1977.
27. Guerrant RL. The microbial diarrheas. In: Current Concepts of Infectious Diseases. Hook E, Mandell G, Gwaltney J and Sande, M, Editors. John Wiley and Sons, Inc., New York, 1977.
28. Pestana de Castro AF, Serafim MB, Rangel HA and Guerrant RL. Swiss and inbred mice in the infant mouse test for the assay of Escherichia coli thermostable enterotoxin. Infect Immun 22:972-974, 1978.
29. Bergman MJ, Guerrant RL, Murad F, Richardson SH, Weaver D and Mandell G. Interaction of polymorphonuclear neutrophils with Escherichia coli: Effect of enterotoxin on phagocytosis, killing and chemotaxis and cyclic AMP. J Clin Invest 61:227-234, 1978.
30. Guerrant RL. Enteric infections. VA Med Monthly 105:443-445, 1978.
31. Hughes JM, Murad F, Chang B and Guerrant RL. Role of cyclic GMP in the action of heat-stable enterotoxin of Escherichia coli. Nature 271:755-756, 1978.
32. Bergman MJ, Evans DG, Mandell GL, Sullivan JA, Salit IE and Guerrant RL. Attachment of E. coli to human intestinal epithelial cells: A functional, in vitro test for intestinal colonization factor. Trans Assoc Amer Phys 91:80-89, 1978.
33. Guerrant RL, Lahita RG, Winn WC and Roberts RB. Campylobacteriosis in man: Pathogenic mechanisms and review of 91 bloodstream infections. Am J Med 65:584-592, 1978.
34. Guerrant RL. Infectious gastrointestinal syndromes. In: Principles and Practice of Infectious Diseases, Chapter 70. Mandell GL, Douglas RG Jr and Bennett JE, Editors. John Wiley and Sons, Inc., New York, 1979.
35. Guerrant RL and Hughes JM. Nausea, vomiting, and noninflammatory diarrhea. In: Principles and Practice of Infectious Diseases, Chapter 71. Mandell GL, Douglas RG Jr and Bennett JE, Editors. John Wiley and Sons, Inc., New York, 1979.
36. Guerrant RL. Inflammatory enterides. In: Principles and Practice of Infectious Diseases, Chapter 72. Mandell GL, Douglas RD Jr and Bennett JE, Editors. John Wiley and Sons, Inc., New York, 1979.
37. Hughes JM and Guerrant RL. Systemic syndromes complicating gastrointestinal infections. In: Principles and Practice of Infectious Diseases, Chapter 73. Mandell GL, Douglas RG Jr and Bennett JE, Editors. John Wiley and Sons, Inc., New York, 1979.
38. Korzeniowski OM, Barada FA, Rouse JD and Guerrant RL. Value of examination for fecal leukocytes in the early diagnosis of shigellosis. Am J Trop Med Hyg 28:1031-1035, 1979.
39. Klipstein FA, Guerrant RL, Wells JG, Short HB and Engert RF. Comparison of assay of coliform enterotoxins by conventional techniques versus in vivo intestinal perfusion. Infect Immun 25:146-152, 1979.
40. Guerrant RL and Bergman MJ. Attachment factors among enterotoxigenic E. coli. In: Frontiers of Knowledge in the Diarrheal Diseases. Janowitz HD and Sachar, DB, Editors. First International Colloquim in Gastroenterology, London, 1979.
41. Hughes JM, Rouse JD, Barada FA and Guerrant RL. Etiology of summer diarrhea among the Navajo. Am J Trop Med Hyg 29:613-619, 1980.
42. Ravdin JI and Guerrant RL. Studies on the cytopathogenicity of Entamoeba histolytica. Arch Invest Med (Mex) II (Suppl 1): 123-128, 1980.
43. Guerrant RL and Ravdin JI. A case of antibiotic-induced pseudomembranous colitis prior to vancomycin. Bac-Data Perspective on Infection 4:1-4, 1980.
44. Guerrant RL. Yet another pathogenic mechanism for E. coli diarrhea? N Engl J Med 302:113-114, 1980.
45. Guerrant RL, Rouse JD and Hughes JM. Turista among members of the Yale Glee Club in Latin America. Am J Trop Med Hyg 29:895-900, 1980.
46. Barada FA and Guerrant RL. Sulfamethoxazole-trimethoprim versus ampicillin in treatment of acute invasive diarrhea in adults. Antimicrob Agents Chemother 17:961-964, 1980.
47. Guerrant RL, Hughes JM, Chang B, Robertson DC and Murad F. Activation of intestinal guanylate cyclase by heat-stable enterotoxin of Escherichia coli: Studies of tissue specificity, potential receptors and intermediates. J Infect Dis 142:220-228, 1980.
48. Ravdin JI, Croft BY and Guerrant RL. Cytopathogenic mechanisms of Entamoeba histolytica. J Exp Med 152:377-390, 1980.
49. Greenberg RN, Murad F, Chang B and Guerrant RL. Inhibition of Escherichia coli heat-stable enterotoxin by indomethacin and chlorpromazine. Infect Immun 29:908-913, 1980.
50. Hughes JM and Guerrant RL. Gastrointestinal infections. In: Handbook of Hospital Acquired Infections, pp 539-562. Wenzel RP, Editor. CRC Press, Inc., Florida, 1981.
51. McLean M, Brennan R, Hughes JM, Korzeniowski OM, de Souza MA, Araujo JG, Benevides T and Guerrant RL. Etiology and oral rehydration therapy of childhood diarrhea in northeastern Brazil. Bull PAHO 15:318-326, 1981.
52. Greenberg RN and Guerrant RL. E. coli heat-stable enterotoxin. Pharmacol Ther 13:507-531, 1981.
53. Spyker DA and Guerrant RL. Dosage nomograms for aminoglycoside antibiotics. Hospital Formulary 16:132-139, 1981.
54. Ravdin JI and Guerrant RL. Food poisoning. In: Current Therapy. Conn H, Editor. W.B. Saunders Co., Pennsylvania, 1981.
55. Guerrant RL, Wood SJ, Krongaard L, Reid RA and Hodge RH. Resistance among fecal flora of patients taking sulfamethoxazoletrimethoprim or trimethoprim alone. Antimicrob Agents Chemother 19:33-38, 1981.
56. Guerrant RL, Brush J, Ravdin JI, Sullivan JA and Mandell GL. Interaction between Entamoeba histolytica and human polymorphonuclear leukocytes. J Infect Dis 143:83-93, 1981.
57. Ellis AR, Mayers DL, Martone WJ, Mitchell BL, Atuk NO and Guerrant RL. Rapidly expanding pulmonary nodule caused by pittsburgh pneumonia agent. JAMA 245:1558-1559, 1981.
58. Kossack RE, Guerrant RL, Densen P, Schadelin J and Mandell GL. Diminished neutrophil oxidative metabolism following phagocytosis of virulent Salmonella typhi. Infect Immun 31:674-678, 1981.
59. Guerrant RL and Sauer KT. Selective use of microbiological tools in identification of etiologic agents of diarrhea illnesses. Journal of Food Safety 3:145-164, 1981.
60. Bergman MJ, Updike WS, Wood SJ, Brown III SE and Guerrant RL. Attachment factors among enterotoxigenic Escherichia coli from patients with acute diarrhea from diverse geographic areas. Infect Immun 32:881-888, 1981.
61. Shields DS, Nations-Shields M, Hook EW, Araujo JG, de Souza MA and Guerrant RL. Electrolyte/glucose concentration and bacterial contamination in home-prepared oral rehydration solution: A field experience in northeastern Brazil. J Pediatr 98:839-841, 1981.
62. Ravdin JI and Guerrant RL. Role of adherence in cytopathogenic mechanisms of Entamoeba histolytica. Study with mammalian tissue culture cells and human red blood cells. J Clin Invest 68:1305-1313, 1981.
63. Greenberg RN, Murad F and Guerrant RL. Lanthanum chloride inhibition of the secretory response to E. coli heat-stable enterotoxin. Infect Immun 35:483-88, 1982.
64. Greenberg RN, Pearson RD, Innes DJ, Sauer KT, Halterman LD and Guerrant RL. Susceptibility of Shigella to erythromycin. Antimicrob Agents Chemother 21:347-348, 1982.
65. Ravdin JI and Guerrant RL. Separation of adherence, cytolytic, and phagocytic events in the cytopathogenic mechanisms of Entamoebay histolytica. Arch Invest Med (Mex) 13(3):123-128, 1982.
66. Greenberg RN, Guerrant RL, Chang B, Robertson DC and Murad F. Inhibition of Escherichia coli heat-stable enterotoxin effects on intestinal guanylate cyclase and fluid secretion by quinacrine. Biochem Pharmacol 31:2005-2009, 1982.
67. Ravdin JI and Guerrant RL. A review of the parasite cellular mechanisms involved in the pathogenesis of amebiasis. Rev Infect Dis 4:1185-1207, 1982.
68. Haley CE and Guerrant RL. Institutional salmonellosis. Asepsis 4:7-12, 1982.
69. Brown SE III, Sauer KT, Nations-Shields M, Shields DS, Araujo JG and Guerrant RL. Comparison of paired whole milk and dried filter paper samples for anti-enterotoxin and anti-rotavirus activities. J Clin Microbiol 16(1):103-106, 1982.
70. Ravdin JI, Sperelakis N and Guerrant RL. Effect of ion channel inhibitors on the cytopathogenicity of Entamoeba histolytica. J Infect Dis 146:335-340, 1982.
71. Guerrant RL and Ravdin JI. Infections caused by Vibrio and Campylobacter: Campylobacter infections. In: Internal Medicine: A Systematic Approach, pp 1370-1371. Stein J, Sande MA et al., Editors. Little, Brown and Company, Boston, 1983.
72. Ravdin JI and Guerrant RL. Rotaviruses. In: Internal Medicine: A Systematic Approach, pp 1288-1289. Stein J, Sande MA, et al., Editors. Little, Brown, and Company, Boston, 1983.
73. Ravdin JI and Guerrant RL. Norwalk agent. In: Internal Medicine: A Systematic Approach, pp 1302-1303. Stein J, Sande MA, et al., Editors. Little, Brown and Company, Boston, 1983.
74. Ravdin JI and Guerrant RL. Infections caused by Vibrio and Campylobacter: Vibrio cholerae. In: Internal Medicine: A Systematic Approach, pp 1367-1369. Stein J, Sande MA, et al., Editors. Little Brown and Company, Boston, 1983.
75. Ravdin JI and Guerrant RL. Infections caused by Vibrio and Campylobacter: Vibrio parahemolyticus and other pathogenic vibrios. In: Internal Medicine: A Systematic Approach, pp 1369-1370. Stein J, Sande MA, et al., Editors. Little, Brown and Company, Boston, 1983.
76. Guerrant RL and Greenberg RN. Approach to gastrointestinal infections. In: Internal Medicine: A Systematic Approach. Stein J, Sande MA et al., Editors. Little, Brown and Company, Boston, 1983.
77. Marcey SM and Guerrant RL. Microorganisms responsible for neonatal diarrhea. In: Infectious Diseases of the Fetus and Newborn Infants, Chapter 27. Remington JS and Klein JO, Editors. W.B. Saunders Co., Philadelphia, 1983.
78. Guerrant RL. Pathophysiology of the enterotoxic and viral diarrheas. In: Diarrhea and Malnutrition: Interactions,Mechanisms, and Interventions, Chapter 2. Chen LC and Scrimshaw NS, Editors. Plenum Press, New York, 1983.
79. Guerrant RL and Hook EW. Salmonella infections. In: Harrison's Principles of Internal Medicine. Petersdorf RG, Adams RD, Braunwald E, Isselbacher KJ, Martin JB and Wilson D, Editors. McGraw Hill Inc., New York, 1983.
80. Ravdin JI and Guerrant RL. Infectious diarrhea in the elderly. Geriatrics 38:95-101, 1983.
81. Hill DR, Guerrant RL, Pearson RD and Hewlett EL. Giardia lamblia infection of suckling mice. J Infect Dis 147:217-221. 1983.
82. Hewlett EL, Sauer KT, Myers GA, Cowell JL and Guerrant RL. Induction of a novel morphologic response in Chinese hamster ovary cells by pertussis toxin. Infect Immun 40:1198-1203, 1983.
83. Greenberg RN, Dunn JA and Guerrant RL. Reduction of the secretory response to Escherichia coli heat stable enterotoxin (ST) by thiol and disulfide compounds. Infect Immun 41:174-180, 1983.
84. Pearson RD and Guerrant RL. Praziquantel: a major advance in anthelmintic therapy. Ann Int Med 99:195-198, 1983.
85. Guerrant RL, Kirchhoff LV, Shields DS, Nations MK, Leslie J, de Souza MA, Araujo JG, Correia LL, Tiemens KM, McClelland KE, Trowbridge FL and Hughes JM. Prospective study of diarrheal illnesses in northeastern Brazil: patterns of disease, nutritional impact, etiologies and risk factors. J Infect Dis 148:986-997, 1983.
86. Guerrant RL and Ravdin JI. Giardia lamblia and Entamoeba histolytica. In: Sexually Transmitted Diseases, Chapter 50. Holmes, Mardh, Sparling and Wiesner, Editors. McGraw-Hill Book Co., 1984.
87. Guerrant RL. E. coli and related enteric pathogens. In: Tropical and Geographic Medicine. Warren KS and Mahmoud AF, Editors. 1984.
88. Weikel CS and Guerrant RL. Food poisoning. In: Current Emergency Therapy - 1984. Edlich RF and Spyker DA, Editors. Appleton-CenturyCrofts, Norwalk, Conn, 1984.
89. Nations, MK, Shields DS, Araujo JG, de Souza MA and Guerrant RL. Care within reach: appropriate health delivery in the developing world. Letter. N Engl J Med 310(24):1612, 1984.
90. Pearson RD, Hewlett EL, Guerrant RL. Tropical diseases in North America. Disease A Month, 1984.
91. Hughes JH and Guerrant RL. Section K: Gastrointestinal infections and food poisoning. Chapter 78: Systemic Syndromes Complicating Gastrointestinal Infections. In: Principles and Practice of Infectious Diseases, (Gastrointestinal Infections Section), pp 669. Mandell, Douglas and Bennett, Editors. John Wiley & Sons, 1984.
92. Korzeniowski OM, Dantas W, Trabulsi LR and Guerrant RL. A controlled study of endemic sporadic diarrhea among adult residents of Southern Brazil. Trans Roy Soc Trop Med Hyg 78:363-369, 1984.
93. Pennie RA, Zunino JN, Rose E and Guerrant RL. Economical, simple method for the production of the gaseous environment required for the cultivation of Campylobacter jejuni. J Clin Microbiol 20(3):320-322, 1984.
94. Guerrant RL. Escherichia coli heat-stable toxin: role for cyclic guanosine 5'-monophosphate in enteric disease. In: Moss J, moderator. Cyclic Nucleotides: Mediators of Bacterial Toxin Action in Disease. Ann Intern Med 101:653-66, 1984.
95. Tiemens KM, Shipley PL, Correia RA, Shields DS, and GuerrantRL. Sulfamethoxazole-trimethoprim resistant Shigella flexneri in northeastern Brazil. Antimicrob Agents Chemother 25:653-654, 1984.
96. Kennedy DJ, Greenberg RN, Dunn JA, Abernathy R, Ryerse JS, and Guerrant RL. Effects of Escherichia coli Heat-Stable Enterotoxin STb on intestines of Mice, Rats, Rabbits, and Piglets. Infect Immun 46(3):639-643, 1984.
97. Long-Krug SA, Weikel CS, Tiemens KT, Hewlett EL, Levine MM, Guerrant RL. Does enteropathogenic Escherchia coli produce heat-stable enterotoxins a or b, or cholera toxin A subunits? Infect Immun 46:612-14, 1984.
98. Guerrant RL. Section K: Gastrointestinal Infections and Food Poisoning. Chapter 75: Principles and Definition of Syndromes. Gastrointestinal Infections Section in: Principles and Practice of Infectious Diseases, Mandell, Douglas, and Bennett (ed), John Wiley & Sons, 635, 1985.
99. Guerrant RL, Hughes JM. Section K: Gastrointestinal Infections and Food Poisoning. Chapter 76: Nausea, Vomiting, and Noninflammatory Diarrhea. Gastrointestinal Infections Section in: Principles and Practice of Infectious Diseases, Mandell, Douglas, and Bennett (ed), John Wiley & Sons, 646, 1985.
100. Guerrant RL. Section K: Gastrointestinal infections and Food Poisoning. Chapter 77: Inflammatory Enteritides. Gastrointestinal Infections Section in: Principles and Practice of Infectious Diseases, Mandell, Douglas, and Bennett (ed), John Wiley & Sons, 660, 1985.
101. Guerrant, RL. Microbial Toxins and Diarrheal Diseases: Introduction and Overview. CIBA Foundation Symposium 112, 1985.
102. Weikel CS, Guerrant RL. STb enterotoxin of Escherichia coli: cyclic nucleotide independent secretion. CIBA Foundation Symposium 112, 1985.
103. Guerrant RL, Holmes RK, Robertson DC, and Greenberg RN. Roles of enterotoxins in the pathogenesis of E. coli diarrhea: Roles of Enterotoxins. Microbiology-1985, pp. 68-73, 1985.
104. Guerrant RL, Shields DS, Thorson SM, Schorling JB, Groschel DHM. Evaluation and Diagnosis of Acute Infectious Diarrhea. Am J Med 78:91-98, 1985.
105. McAuliffe JF, de Souza MA, Nations MK, Shields DS, Tavares IL, Leslie J, Araujo G, Guerrant RL. Prospective studies of the illness burden in a rural community in the Northeast of Brazil. Bull PAHO, 19:139-146, 1985.
106. Weikel CS, Johnston LI, de Sousa MA, Guerrant RL. Cryptosporidiosis in Northeastern Brazil: Association with sporadic diarrhea, J Infect Dis 151:963-65, 1985.
107. Kirchhoff LV, McClelland KE, Pinho MDC, Araujo JG, de Sousa MA, Guerrant RL. Feasibility and efficacy of in-home water chlorination in rural Northeastern Brazil. J Hyg 94:173-80, 1985.
108. Chandler JG, Adams RB, Friedman CL, Marcella KL, Guerrant RL. Assessment of an implantable ileostomy sphincter. Surgery 98:72-80, 1985.
109. Ravdin JI, Murphy CF, Salata RA, Guerrant RL, and Hewlett EL. N-Acetyl-D-Galactosamine inhibitable adherence lectin of Entamoeba histolytica. I. Partial purification and relationship to amoebic virulence in vitro. J Infect Dis 151:804-815, 1985.
110. Ravdin JI, Guerrant RL, Sperelakis N. Entamoeba histolytica: Impedance measurements and cytotoxicity in the presence of bepridil, verapamil, and cytochalasin D. Exp Parasitol, 60:63-72, 1985.
111. Ravdin JI, Murphy CF, Guerrant RL, Long-Krug, SA. Effect of antagonists of calcium and phospholipase A the cytopathogenicity of Entamoeba histolytica. J Infect Dis 152:542-549, 1985.
112. Thorson SM, Lohr JA, Dudley S, Guerrant RL. Value of Methylene blue examination, dark-field microscopy, and carbol-fuchsin Gram stain in the detection of Campylobacter jejuni. J Pediatr 106:941-43, 1985.
113. Weikel CS, Guerrant RL. Nosocomial salmonellosis. Infect Control 6(6):218-20, 1985.
114. Ravdin JI, John JE, Johnston LI, Innes DJ, Guerrant, RL. Adherence of Entamoeba histolytica trophozoites to rat and human colonic mucosa. Infect Immun 48:292-297, 1985.
115. Weikel CS, Sando JJ, Guerrant RL. Stimulation of porcine jejunal ion secretion in vivo by protein kinase-C activators. J Clin Invest 76:2430-2435, 1985.
116. Guerrant RL, Blaser MJ. Pathogenesis and toxins. In: Campylobacter III. Ed. by Pearson AD, Skirrow MB, Lior H, and Rowe B. London: Public Health Laboratory Service, 114-116, 1985.
117. Greenberg RN and Guerrant RL. E. coli heat-stable enterotoxin. In: International Encyclopedia of Pharmacology and Therapeutics, Chapter 6, pp 115-151, 1986.
118. Weikel CS, Long-Krug S, and Guerrant RL. E. coli STb: A new mechanism for secretory diarrhea. In: Advances in Research on Cholera and Related Diarrheas 03, pp 333-341. Ed by S Kuwahara and NF Pierce, KTK Scientific Publishers, Tokyo, Japan, 1986. (Proceedings of the 19th Joint Conference on Cholera-US Japan Cholera Panel, NIH, October, 1983.)
119. Weikel CS, Guerrant RL. Infectious Diarrhea - A Patient in the United States. In: Current Therapy in Infectious Disease, 2nd Ed., pp 165-171. E.H. Kass, Editor. Philadelphia, 1986.
120. Ravdin JI and Guerrant RL. Current Problems in Diagnosis and Treatment of Amebic Infections. In: Current Concepts in Infectious Disease, pp. 82-111. Remington and Schwartz, Editors. McGraw-Hill Book Co., New York, 1986.
121. Guerrant RL. The global problem of amebiasis: Current status research needs and opportunities for progress: Introduction, Current Status, Research Questions. Rev Infect Dis 8:218-227, 1986.
122. Bodey GP, Fainstein V, Guerrant RL. Infections of the Gastrointestinal Tract in the immunocompromised patient. Ann Rev Med 37:271-281, 1986.
123. Greenberg RN and Guerrant RL. E. coli heat-stable enterotoxin. Chapter 6 In Microbial Toxins. Dorner F, Editor. Pergammon Press, 1986.
124. Weikel CS and Guerrant RL. Salmonellosis (other than typhoid fever). In: Conn's Current Therapy, 1986.
125. Guerrant RL. Unresolved problems and future considerations in diarrheal research. Pediatr Infect Dis 5(1):s155-s166, 1986.
126. Guerrant RL and McAuliffe J. Special Problems in Developing Countries. In: Infectious Diarrhea, pp. 287-307. Gorbach SL, Editor. Blackwell Sci Publ, Boston, 1986.
127. Pennie, RA, Pearson RD, Barrett LJ, Lior H and Guerrant RL. Susceptibility of Campylobacter jejuni in strain-specific bactericidal activity in sera of infected patients. Infect Immun, 52:702-706, 1986.
128. Guerrant RL, Lohr JA and Williams EK. Acute Infectious Diarrhea. I. Epidemiology, Etiology and Pathogenesis. Pediatr Infect Dis 5:353-359, 1986.
129. Williams EK, Lohr JA and Guerrant RL. Acute Infectious Diarrhea. II. Diagnosis, treatment and prevention. Pediatr Infect Dis. 5:458-465, 1986.
130. Weikel CS, Nellans HN and Guerrant RL. The in vivo and in vitro effects of a Novel Enterotoxin, STb, Produced by Escherichia coli. J Infect Dis 153:893-901, 1986.
131. Weikel CS, Tiemens K, Moseley S and Guerrant RL. Species Specificity and Lack of production of STb enterotoxin by Escherichia coli Strains Isolated from Humans with Diarrheal Illness. Infect Immun 52:323-325, 1986.
132. McAuliffe JF, Shields DS, de Souza MA, Sakell J, Schorling J and Guerrant RL. Prolonged and Recurring Diarrhea in the Northeast of Brazil: Examination of Cases from a Community-based Study. J Ped Gastroenterol Nutrition 5:902-906, 1986.
133. Guth BEC, Pickett CL, Twiddy EM, Holmes RK, Gomes TAT, Lima AAM, Guerrant RL, Franco BDGM and Trabulsi LR. Production of Type II heat-labile enterotoxin (LT-II) by Escherichia coli isolated from food and human feces. Infect Immun 54:587-589, 1986.
134. Wanke CA, Lima AAM and Guerrant RL. Infectious Diarrhea in Tropical and Subtropical Regions. In: Bailliere's Clinical Gastroenterology. Gyr K, Editor, 1987.
135. Guerrant RL, Wanke CA, Barrett LJ and Schwartzman JD. A Cost Effective and Effective Diagnosis and Management of Acute Infectious Diarrhea. Bull NY Acad Med 63:484-499, 1987.
136. Guerrant RL, Wanke CA, Pennie RA, Barrett LJ, Lima AAM and O'Brien AD. Studies of a toxin from Campylobacter jejuni. J Infect Dis 155(6):1352-1356. (Twenty second Cholera Symposium Toyama 1986), 1987.
137. Guerrant RL. Salmonella Infections. In: Harrison's Textbook of Medicine, 11th Ed, Chapter 107 pp 592-599. Braunwald, et al. W.B. Saunders Co., Philadelphia, 1987.
138. Pearson RD and Guerrant RL. Shigellosis. In: Harrison's Textbook of Medicine, 11th Ed, Chapter 108, pp 599-601. Braunwald et al., Editors. W.B. Saunders Co., Philadelphia, 1987.
139. Guerrant RL and Schwartzman JD. Introduction and Overview of Intestinal Nematode Infections. In: Clinical Medicine. Strickland GT, Editor. J.P. Lippincott Co., 1987.
140. Pearson RD and Guerrant RL. Intestinal nematodes that invade the skin and lungs (Hookworm and Strongyloides stercoralis). In: Clinical Medicine. Strickland GT, Editor. J.P. Lippincott Co., 1987.
141. Weikel CS and Guerrant RL. Rotaviruses. In: Internal Medicine, Chapter 242, pp 1603-1605. Stein JH, Editor. Little, Brown, and Co, 1987.
142. Weikel CS and Guerrant RL. Norwalk-like agents. In: Internal Medicine, Chapter 246, pp 1620-1621. Stein JH, Editor. Little, Brown and Company, 1987.
143. Wilson ME and Guerrant RL. Infections caused by vibrios. In: Internal Medicine, Chapter 261, pp 1687-1691. Stein JH, Editor. Little, Brown and Company, 1987.
144. Schorling JB, Schwartzman JD and Guerrant RL. Resistant Bacteria: A Growing Problem. Hosp Therapy, pp 71-89, April 1987.
145. Kunin CM, Lipton HL, Tupasi T, Sackes T, Schechler W, Jivani A, Goic A, Martin RR, Guerrant RL and Thamllkitkul V. Social, Behavorial and Practical Factors Affecting Antibiotic Use Worldwide. Rev Infect Dis 9:S270-S285, May-June 1987.
146. Wanke CA and Guerrant RL. Small Bowel Colonization Alone is a Cause of Diarrhea: A Rabbit Model. Infect Immun 55:1924-1926, August 1987.
147. Ravdin JI and Guerrant RL. Eradication of amebiasis: extent of the problem and research needs. In: Amebiasis: Human Infection by Entamoeba histolytica, Chapter 4. Ravdin JI, Editor. John Wiley and Sons, New York, 1987.
148. Guerrant RL and Ravdin JI. Future direction in research on amebiasis. In: Amebiasis: Human Infection by Entamoeba histolytica, Chapter 46. Ravdin JI, Editor. John Wiley and Sons, New York, 1987.
149. Wanke CA and Guerrant RL. Viral hepatitis and gastroenteritis transmitted by shellfish and water. In In Infectious Disease Clinics of North America, pp 649-664. Moellering RC Jr and Sanders WE Jr, Editors. Philadelphia, 1987.
150. Tucker RM, Gaffey MJ, Fisch MJ, Kaiser DL, Guerrant RL and Normansell DE. SeroEpidemiology of Hepatitis D (Delta Agent) and Hepatitis B among Virginia State Prisoners. Clin Therapeut 9:622-628, 1987.
151. Guerrant RL, Wanke CA, Pennie RA, Barrett LJ, Lima AAM and O'Brien AD. Production of a unique cytotoxin by Campylobacter jejuni. Infect Immun 55:2526-2530, 1987.
152. Evans TG and Guerrant RL. Acute Infectious Diarrhea. Conn's Current Therapy-1988, pp 11-14. Rakel RE, Editor, 1988.
153. Guerrant RL and Weikel CS. Pharmacologic pathways leading to intestinal secretion: Stimulation by enterotoxins and by C-kinase activators. In: Advances in Research on Cholera and Related Diarrheas, pp 181-188. Kuwahara S and Pierce NF. KTK Scientific Publication, Tokyo, 1988.
154. Wanke C and Guerrant RL. Infectious Gastroenteritis. In: Medicine for the Practicing Physician, 2nd Ed, Chapter 160, pp 322-324. Hurst JW, Editor. Butterworth Publishers, Boston, 1988.
155. Guerrant RL. Campylobacter enteritis. In: Cecil Textbook of Medicine, 18th Edition, pp 1648-1651. Wyngaarden JB and Smith LH, Editors. WB Saunders Co, Philadelphia, PA, 1988.
156. Guerrant RL. Enteric Escherichia coli infections. In: Cecil Textbook of Medicine, Ch 288, pp 1653-1656. Wyngaarden JB and Smith, Editors, 1988.
157. Schlager TA and Guerrant RL. Seven possible pathogenic mechanisms for E. coli diarrhea. Infect Dis Clin Am 2:607-624, 1988.
158. Guerrant RL, Afrookteh A, Sturgill B and Hewlett EL. Abdominal pain and fever. Clinical Pathology Conference. Va Med, pp 280-286, June, 1988.
159. Carter TR, Cooper PH, Petri WA Jr, Kim CK, Walzer PD and Guerrant RL. Pneumocystis carinii infection of the small intestine in a patient with AIDS. Am J Clin Pathol 89:679-683, 1988.
160. Lima AAM, Lyerly DM, Wilkins TD, Innes DJ and Guerrant RL. Effects of Clostridum difficile toxins A and B in rabbit small and large intestine in vivo and on cultured cells in vitro. Infect Immun 56:582-588, 1988.
161. Mata L and Guerrant RL. Magnitude and Impact of diarrhoeal disease. In: Bailliere's Clinical Tropical Medicine and Communicable Diseases, Vol 3, No 3, Chapter 4, pp 435-446, 1988.
162. Crane JK and Guerrant RL. Enterotoxic enteropathies. In: Bailliere's Clinical Tropical Medicine and Communicable Diseases, Vol 3, No 3, Chapter 5, pp 447-462, 1988.
163. Ravdin JI, Weikel CS and Guerrant RL. Protozoan enteropathies: cryptosporidiosis, giardiasis, and amoebiasis. In: Bailliere's Clinical Tropical Medicine and Communicable Diseases, Vol 3, No 3, Chapter 8, pp 503-536, 1988.
164. Guerrant RL. Vaccines Against Enteric Infections. Current Opinion in Infectious Diseases 1:868-876, 1988.
165. Wanke C and Guerrant RL. Enterotoxigenic E. coli. In: Enteric Infection, Chapter 17, pp. 253-263. Farthing MJG and Keusch GT, Editors, 1989.
166. Guerrant RL and Marshall BJ. Human Campylobacter infections. Infect Med 6:9-14, 1989.
167. Guerrant RL. 7.1 Diarrheal Diseases and Enteric Fever: General Considerations. In: Tropical Medicine and Medical Parasitology, pp 86-89. Goldsmith RS and Heyneman D, Editors. Appleton and Lange Publications, Norwalk, Connecticut, 1989.
168. McAuliffe JF and Guerrant RL. 7.2 Approach to Treatment of Acute Diarrhea. pp 90-94 In: Tropical Medicine and Medical Parasitology, RS Goldsmith, D Heyneman, Editors. Appleton and Lange Publications, Norwalk, Connecticut, 1989.
169. Hewlett EL and Guerrant RL. 7.4 Escherichia coli Disease. In: Tropical Medicine and Medical Parasitology, pp 101-104. Goldsmith RS and Heyneman D, Editor. Appleton and Lange Publications, Norwalk, Connecticut, 1989.
170. Ravdin JI and Guerrant RL. 7.5 Viral Gastroenteritis (Rotaviruses, Norwalk-like Viruses, Enteroviruses). In: Tropical Medicine and Medical Parasitology, pp 105-107. Goldsmith RS and Heyneman D, Editors. Appleton and Lange Publications, Norwalk, Connecticut, 1989.
171. Hill DR and Guerrant RL. 7.6 Salmonellosis (Including Typhoid fever). In: Tropical Medicine and Medical Parasitology, pp 108-116. Goldsmith RS and Heyneman D, Editors. Appleton and Lange Publications, Norwalk, Connecticut, 1989.
172. Pearson RD and Guerrant RL. 7.8 Campylobacter Enterocolitis. In: Tropical Medicine and Medical Parasitology, pp 122-125. Goldsmith RS and Heyneman D, Editors. Appleton and Lange Publications, Norwalk, Connecticut, 1989.
173. Hewlett EL and Guerrant RL. 7.10 Traveler's Diarrhea. In: Tropical Medicine and Medical Parasitology, pp 127-129. Goldsmith RS and Heyneman D, Editors. Appleton and Lange Publications, Norwalk, Connecticut, 1989.
174. Guerrant RL. Escherichia coli and Related Enteric Pathogens. In: Tropical and Geographical Medicine, Second Edition, Chapter 77, pp 776-790. Warren KS and Mahmoud AAF, Editors. McGraw Hill, New York, NY 1989.
175. Schlager TA and Guerrant RL. Rotaviral and Norwalk-like Viral infections. In: Internal Medicine, Third Edition. Stein et al., Editors. Little Brown & Co, Boston, 1989.
176. Wilson ME and Guerrant RL. Infections caused by Vibrios. In: Internal Medicine, Third Edition. Stein et al., Editors. Little Brown & Co, Boston, 1989.
177. Guerrant RL. Inflammatory Enteritides. In: Principles and Practice of Infectious Diseases, 3rd Edition, Chapter 83, pp 870-879. Mandell, Douglas and Bennett, Editors. Churchill Livingstone Inc., 1990.
178. Williams MD, Schorling JB, Barrett LJ, Dudley SM, Orgel I, Koch WC, Shields DS, Thorson SM, Lohr JA and Guerrant RL. Early treatment of Campylobacter jejuni enteritis. Antimicrob Agents Chemother 33:248-250, 1989.
179. Lima AAM, Innes DJ, Chadee K, Lyerly DM, Wilkins TD and Guerrant RL. Clostridium difficile Toxin A: Early sequential histopathologic effects in rabbit small intestine. Lab Invest 61:419-425, 1989.
180. Perez-Perez GI, Cohn DL, Guerrant RL, Patton CM, Reller LB and Blaser MJ. Clinical and immunologic significance of cholera-like toxin and cytotoxin production by Campylobacter species in patients with acute inflammatory diarrhea in the USA. J Infect Dis 160:460-468, 1989.
181. Dye KR, Marshall BJ, Frierson HF Jr, Guerrant RL and McCallum RW. Ultrastructure of another spiral organism associated with human gastritis.Digestive Diseases and Sciences 34 (11):1787-1791, 1989.
182. Guerrant RL. Selected topics and travel-associated diseases: Editorial overview. Curr Opin Infect Dis 2:615-616, 1989.
183. Schwartzman JD and Guerrant RL. Infections with miscellaneous intestinal parasites and toxoplasma. Curr Opin Infect Dis 2:650-655, 1989.
184. Pickering LK, Cleary TG and Guerrant RL. E. coli and Campylobacter diarrhea. AAP Pediatr Update 9:1-9, 1989.
185. Guerrant RL, Weikel CS and Ravdin JI. Intestinal Protozoa: Giardia lamblia, Entamoeba histolytica, and Cryptosporidium. In: Sexually Transmitted Diseases, 2nd Edition, Chapter 44, pp 493-514. Holmes KK, Mardh P, Sparling PF and Wiesner PJ, Editors. McGraw Hill, New York, NY, 1990.
186. Guerrant RL, Petri WA and Weikel CS. Parasitic Causes of Diarrhea. In: Pathophysiology of Secretory Diarrhea, Chapter 19, pp 273-280. Lebenthal E and Duffey M, Editors. Raven Press, Ltd., Boston, MA, 1990.
187. Guerrant RL, Hughes JM, Lima NL and Crane JK. Diarrhea in Developed and Developing Countries: Magnitude, Special Settings and Etiologies. Rev Infect Dis 12:S41-S50, 1990.
188. Guerrant RL, Cleary TG and Pickering LK. Microorganisms responsible for Neonatal Diarrhea. In: Infectious Diseases in the Fetus and Newborn Infant, Third Edition. Remington J and Kline JO, 1990.
189. Guerrant RL. Principles and syndromes of enteric infections. In: Principles and Practice of Infectious Diseases, 3rd Edition, Chapter 81, pp 837-850. Mandell, Douglas and Bennett, Editors. Churchill Livingstone Inc., New York, 1990.
190. Guerrant RL. Nausea, vomiting, and noninflammatory diarrhea. In: Principles and Practice of Infectious Diseases, 3rd Edition, Chapter 82, pp 851-863. Mandell, Douglas and Bennett, Editors. Churchill Livingstone Inc., New York, 1990.
191. Pearson RD and Guerrant RL. Enteric fever and other causes of abdominal symptoms with fever. In: Principles and Practice of Infectious Diseases, 3rd Edition, Chapter 84, pp 880-892. Mandell, Douglas and Bennett, Editors. Churchill Livingstone Inc., New York, 1990.
192. Guerrant RL and Keystone JS. Traveler's Diarrhea. In: Hunter's Tropical Medicine, Seventh Edition, Chapter 117, pp 1031-1034, 1990.
193. Guerrant RL, Schwartzman JD and Pearson RD. Intestinal Nematode Infections: Introduction and Overview. In: Hunter's Tropical Medicine, Seventh Edition, pp 684-689, 1990.
194. Pearson RD, Guerrant RL. Intestinal nematodes that migrate through skin and lungs. In: Hunter's Tropical Medicine, Seventh Edition, Chapter 84, pp 700-711, 1990.
195. Lima AAM, Crane JK, Hewlett EL and Guerrant RL. Possible role of pertussis toxin substrate (? G Proteins) in the regulation of intestinal absorption. Presented at 23rd U.S. Japan Cholera Conference, Tokyo Japan, 1990.
196. Marshall BJ, Barrett LJ, Prakash C, McCallum RW and Guerrant RL. Urea protects Helicobacter (Campylobacter) pylori from the bactericidal effect of acid. Gastroenterology 99:697-702, 1990.
197. Schorling JB, Wanke CA, Schorling SK, McAuliffe JF, de Souza MA and Guerrant RL. A prospective study of persistent diarrhea among children in an urban Brazilian slum: Patterns of occurrence and etiologic agents. Am J Epidemiol 132:144-156, 1990.
198. Schlager TA, Wanke CA and Guerrant RL. Net fluid secretion and impaired villous function induced by colonization of the small intestine by non-toxigenic, colonizing E. coli. Infect Immun 58:1337-1343, 1990.
199. Schorling JB, McAuliffe JF, de Souza MA and Guerrant RL. Malnutrition is associated with increased diarrhoea incidence and duration among children in an urban Brazilian slum. Int J Epidemiol 19(3):728-735, 1990.
200. Lima NL, Guerrant RL, Kaiser DL, Germanson T and Farr BM. A retrospective cohort study of nosocomial diarrhea as a risk factor for nosocomial infection. J Infect Dis 161:948-952, 1990.
201. Schorling JB and Guerrant RL. Diarrhoea and catch-up growth. Lancet 335:599-600, 1990.
202. Crane JK, Guerrant RL and Weikel CS. Phorbol esters potentiate cyclic GMP production by the heat stable enterotoxin of Escherichia coli (STa). Cholera and related diarrheas (from 25th US-Japan Cholera Conference, Grand Canyon, AZ), 1990.
203. Wanke CA, Cronan S, Goss C, Chadee K and Guerrant RL. Characterization of binding of Escherichia coli strains which are enteropathogens to small bowel mucin. Infect Immun 58:794-800, 1990.
204. Araujo V and Guerrant RL. Nosocomial gastrointestinal infections. Curr Sci 3:521-526, 1990.
205. Crane JK, Burrell LL, Weikel CS and Guerrant RL. Carbachol mimics phorbol esters in its ability to enhance cyclic GMP production by STa, the heat-stable toxin of Escherichia coli. FEBS, 274(1,2):199-202, 1990.
206. Guerrant, RL, Fang GD, Lima AM, Schorling JB and Wanke CA. Potential role of colonizing E. coli in prolonged diarrhea among young children in northeast Brazil. US-Japan Cholera Meetings in Kyoto, September, 1990.
207. Petri WA Jr, Hill DR and Guerrant RL. Protozoan Diseases. In: Textbook of Gastroenterology, First Edition, Chapter 104, pp 2103-2118, Yamada T et al., Editors. JB Lippincott Co., 1991.
208. Schorling JB, de Souza MA and Guerrant RL. Antibiotic use among children in an urban Brazilian slum: A risk factor for diarrhea? Am J Publ Health 81:99-100, 1991.
209. Schorling JB, de Souza MA and Guerrant RL. Patterns of antibiotic use among children in an urban Brazilian slum. Int J Epidemiol 19(4):293-299, 1991.
210. Hazen KC and Guerrant RL. Selected fungal and protozoan enteric infection: Candida, Blastocystis, Cryptosporidium, and Giardia. Curr Opi Infect Dis 4(1):74-83, 1991.
211. Fang G, Araujo V and Guerrant RL. Enteric infections associated with exposure to animals or animal products. Infect Dis Clin N Am 5(3)681-701, 1991.
212. Gardner AL, Roche JK, Weikel CS and Guerrant RL. Intestinal cryptosporidiosis: Pathophysiologic alterations and specific cellular and humoral immune responses in rnu/+ and rnu/rnu (athymic) rats. Am J Trop Med Hyg 44:49-62, 1991.
213. Marshall BJ, Plankey MW, Hoffman SR, Boyd CL, Dye KR, Frierson HF Jr, Guerrant RL and McCallum RW. A 20-minute breath test for Helicobacter pylori. Am J Gastroentrol 86(4):438-445, 1991.
214. Guerrant RL and Bobak DA. Bacterial and protozoal gastroenteritis. N Engl J Med 325:327-340, 1991.
215. Arruda E, Hayden FG, McAuliffe JF, de Sousa MA, Mota SB, McAuliffe MI, Geist FC, Carvalho EP, Fernandes, MC, Guerrant RL and Gwaltney JM. Acute respiratory viral infections in ambulatory children of urban Northeast Brazil. J Infect Dis 164(2):252-258, 1991.
216. Lima AAM, Soares JE, Freire JE and Guerrant RL. Glutamine increases intestinal sodium absorption despite cholera toxin-induced secretion: a potential improved oral rehydration therapy. US-Japan Cholera Meetings in Charlottesville, September, 1991.
217. Fonteles MC, Lima AAM, Fang G and Guerrant RL. Effect of STa and cholera toxin on renal electrolyte transport: Possible roles of and endogenous ST-like compound in the isolated kidney. Minireport. US-Japan Cholera Meetings in Charlottesville, September, 1991.
218. Wanke CA, Schorling JB, Barrett LJ, de Souza MA and Guerrant RL. Potential role in pathogenesis of persistent diarrhea in an urban Brazilian slum. Pediatr Infect Dis J 10:746-751, 1991.
219. Guerrant RL and Crane JK. Chapters on Brucellosis, Bartonellosis, Tularemia, Hemophilus, Enterobacteriaceae, Salmonella and Shigella infections, pp 84-112. In: The Merck Manual, West Point, PA, 1991.
220. Araujo V and Guerrant RL. Nosocomial gastrointestinal infections. Current Opinion in Infectious Diseases 4:549-555, 1991.
221. Lind CD, Davis RH, Guerrant RL, Kaper JB and Mathias JR. Effects of Vibrio cholerae recombinant strains on rabbit ileum in vivo: enterotoxin production and myoelectric activity. Gastroenterology 101(2):319-324, 1991.
222. Lind CD, Guerrant RL, Kurosky A and Mathias JR. Purified choleragenoid does not induce migrating action potential complex activity in rabbit ileum in vivo. J Pharm Exp Therap 258(2):647-651, 1991.
223. Sarosiek J, Peura DA, Guerrant RL, Marshall BJ, Laszewicz W, Gabryelewicz A and McCallum RW. Mucolytic effects of Helicobacter pylori. Scand J Gastroenterol 26 (Suppl 187):47-55, 1991.
224. Wanke CA and Guerrant RL. Infectious gastroentritis. In Medicine for the Practicing Physician. Hurst, JW, Editor. Butterworth-Heinemann, 1992.
225. Guerrant RL and Lingwood CA. Interactions of microbial adhesins and toxins with the gastrointestinal mucosa. In: Helicobacter pylori in Peptic Ulceration and Gastritis, pp 66-80. Marshall BJ, McCallum RW and Guerrant RL. Blackwell Scientific Publications, Cambridge, Massachusetts, 1991.
226. Guerrant RL. Diarrheal diseases: new challenges and emerging opportunities. In: Global Infectious Diseases: Prevention, Control and Eradication, pp. 87-102. Walker DH, Editor. Springer-Verlag Wien, New York, 1992.
227. Guerrant RL, Schorling JB, McAuliffe JF and de Souza MA. Diarrhea as a cause and an effect of malnutrition: Diarrhea prevents catch-up growth and malnutrition increases diarrhea frequency and duration. Introduction: Symposium on Nutrition and Infection. Guerrant RL, Kakoma I and Krogstad DJ. Am J Trop Med Hyg 47(1)(Suppl):28-35, 1992.
228. Guerrant RL. Enteric Escherichia coli infections. In Cecil Textbook of Medicine 19th edition, Chapter 318, pp 1701 1704. Wyngaarden JB and Smith H, W.B. Saunders Co., Philadelphia, PA, 1992.
229. Guerrant RL. Campylobacter enteritis. In: Cecil Textbook of Medicine 19th edition, Chapter 316, pp 1696 1699. Wyngaarden JB and Smith H. W.B. Saunders Co., Philadelphia, PA, 1992.
230. Guerrant RL, Hill DR and Petri WA Jr. Parasitic Diseases: Protozoa. In: Atlas of Gastroenterology Chapter 56, pp 386-393. Yamada et al, Editors. J.B Lippincott Co., 1992.
231. Bobak DA and Guerrant RL. New developments in enteric bacterial toxins. Adv Pharmacol 23:85-108, 1992.
232. Lima AAM, Fang GD, Schorling JB, de Albuquerque L, McAuliffe JF, Mota S, Leite R and Guerrant RL. Persistent diarrhea in Northeast Brazil: etiologies and interactions with malnutrition. Acta Paediatr Suppl 381:39-44, 1992.
233. Guerrant RL, Fang G, Pennie RA and Pearson RD. In vitro models for studying Campylobacter jejuni infections. In: Campylobacter jejuni: Current Status and Future Trends, Chapter 17, pp 160 167. Nachamkin I, Blaser MJ and Tompkins LS, Editors. ASM Washington, D.C., 1992.
234. Getchell-White SI, Barrett LJ, Barton BA, Strain BA, Farr BM, Guerrant RL and Groschel DHM. Nosocomial significance of Clostridium difficile: an Epidemiologic study using molecular markers. Med Microbiol Lett 1:49 55, 1992.
235. Zu S, Fang G, Fayer R and Guerrant RL. Cryptosporidiosis: Pathogenesis and Immunology. Parasitology Today 8(1):24 27, 1992.
236. Maloney WJ and Guerrant RL. Epidemiology, therapy and prevention of infection with Salmonella organisms. Curr Opin Infect Dis 5(1):74-79, February 1992.
237. Guerrant RL, Araujo V, Soares E, Kotloff K, Lima AAM, Cooper WH and Lee AG. Measurement of fecal lactoferrin as a marker of fecal leukocytes. J Clin Microbiol 30:1238 -1242, 1992.
238. Lima AAM, Soares AM, Freire JE Jr and Guerrant RL. Cotransport of sodium with glutamine, alanine and glucose in the isolated rabbit ileal mucosa. Brazilian J Med Biol Res 25:637-640, 1992.
239. Lima AAM and Guerrant RL. Persistent diarrhea in children: Epidemiology, risk factors, pathophysiology, nutritional impact and management. Epid Rev 14:222-242, 1992.
240. Higgs ES and Guerrant RL. Diagnosing Intestinal Parasites. Mediguide to Infectious Disease 12(2):18, 1992.
241. Kelsall B and Guerrant RL. Evaluation of diarrhea in the returning traveler. Infect Dis Clin No Am 6(2):413 425, 1992.
242. Walser BL, Newman R, Lima AAM and Guerrant RL. Pathogen and host differences in bacterial adherence to human buccal epithelial cells in a Northeast Brazilian community. Infect Immun 60(11):4793 4800, 1992.
243. Crane JK, Redden MS, Bolen EJ, Sando JJ, Linden J, Guerrant RL and Sears CL. Regulation of intestinal guanylate-cyclase by the heat-stable enterotoxin of Escherichia coli (STa) and protein-kinase-C. Infect Immun 60(12):5004 5012, 1992.
244. Lima AAM and Guerrant RL. The management of cholera today. Mediguide to Infec Dis 5(4):1-5, 1992.
245. Sarosiek J, Marshall BJ, Peura DA, Guerrant RL, McCallum RW and Little C. The isolation and maintenance of human gastric epithelial cells in primary culture. In: Cell & Tissue Culture Laboratory Procedure, pp 12B:10.1-12B:10.7, Briffith JB, Doyle A, Hewell DG and Wiley J, Editors, 1993.
246. Peura DA and Guerrant RL. Achlorhydria and enteric bacterial infections. In: Chronic Gastritis and Achlorhydria in the Elderly. Holt P and Russell RM. CRC Press, Inc., Boca Raton, FL, 1993.
247. Guerrant RL and Guerrant DI. The history of cholera and update on gastrointestinal infections. Curr Opin Infect Dis 6:37 40, 1993.
248. Robins-Browne RM, Takeda T, Fasano A, Bordun A-M, Dohi S, Kasuga H, Fang G, Prado V, Guerrant RL and Morris JG Jr. Assessment of Enterotoxin production by Yersinia enterocolitica and identification of a novel heat-stable enterotoxin produced by a noninvasive Y. enterocolitica strain isolated from clinical material. Infect Immun 61(2):764 767, 1993.
249. Fonteles MC, Villar-Palasi C, Fang G, Larner J and Guerrant RL. Partial characterization of an ANF/urodilatin-like substance released from perfused rabbit kidney under hypoxia. Brazilian J Med Biol Res 26:75 79, 1993.
250. Marshall BJ, Valenzuela JE, McCallum RW, Dooley CP, Guerrant RL, Cohen H, Frierson NF Jr., Field LG, Jerdack GR and Mitra S. Bismuth subsalicylate suppression of Heliocobacter pylori in non-nuclear dyspepsia: a double-blind placebo-controlled trial. Digest Dis Sci 38(9):1674 1680, 1993.
251. Lima NL, Pereira RB, Souza IC, Facanha MC, Lima AAM, Guerrant RL and Farr BM. Selective survillance for nosocomial infections in a Brazilian hospital. Infection Control and Hospital Epidemiology 14(4):197 292, 1993. With editorial by Phillip S. Brachman, pp 194 196.
252. Spriggs DR and Guerrant RL. Summary of the 27th United States-Japan Joint Conference on Cholera and Related diarrheal diseases. J Infect Dis 167:16, 1993.
253. Zu S-X and Guerrant RL. Cryptosporidiosis. J Trop Pediatr 39(3):132 136, 1993.
254. Yotseff PS and Guerrant RL. Clostridium difficile in the elderly. Geriatric Focus, 3(1):16, 1993.
255. Sarosiek J, Namiot Z, Marshall BJ, Peura DA, Guerrant RL, Harlow D and McCallum RW. Breakdown of the mucus layer by H. pylori. In: Helicobacter pylori: Basic mechanisms to clinical care (Proceedings of the International Symposium, Amelia Island, FA), pp. 123-138, Nov 1993.
256. Newman RD, Wuhib T, Lima AAM, Guerrant RL and Sears CL. Environmental sources of Cryptosporidium in an urban slum in Northeastern Brazil. Am J Trop Med Hyg 49(2):270 275, 1993.
257. Newman RD, Jaeger KL, Wuhib T, Lima AAM, Guerrant FL and Sears CL. Evaluation of an antigen capture enzyme-lined immunosorbent assay for detection of Cryptosporidium oocysts. J Clin Microbiol 31(8):2080 2084, 1993.
258. DeCross AJ, Marshall BJ, McCallum RW, Hoffman SR, Barrett, LJ and Guerrant RL. Metronidazole susceptibility testing for Helicobacter pylori: comparison of disk, broth, and agar dilution methods and their clinical relevance. J Clin Microbiol 31(8):1971-1974, 1993.
259. Wilson ME and Guerrant RL. Infections caused by Vibrio species. In: Internal Medicine, Fourth Edition. Stein et al., Editors. Mosby-Year Book, Inc., St. Louis. Chapter 267, pp 2132?2140, 1994
260. Clemence MA and Guerrant RL. At the Shore. In: Infections of Leisure, ed. D. Schlossberg, Springer-Verlag Wein, New York, 1994.
261. Jernigan J, Guerrant RL and Pearson RD. Parasitic infections of the small intestine. Gut 35:289-293, 1994.
262. Newman RD, Zu S-X, Wuhib T, Lima AAM, Guerrant RL and Sears CL. Household Epidemiology of Cryptosporidium parvum infection in an urban community in Northeast Brazil. Ann Int Med 120(6):500-505, 1994.
263. Adams RB, Guerrant RL, Zu S-X, Fang G and Roche JK. Cryptosporidum parvum infection of intestinal epithelium: morphologic and functional studies in an in vitro model. J Infect Dis 169:170-177, 1994.
264. Sears CL and Guerrant RL. Cryptosporiodiosis: The complexity of intestinal pathophysiology. Gastroenterology 106:252-254, 1994. (Editorial)
265. Kunin CM, Hua TH, Guerrant RL and Bakaletz LO. Effect of salicylate, bismuth, osmolytes, and tetracycline resistance on expression of Fimbriae by Escherichia coli. Infect Immun 62(6):2178-2186, 1994.
266. Guerrant RL. Lessons from diarrheal diseases: demography to molecular pharmacology. J Infect Dis 169:1206-1218, 1994.
267. Scerpella EG, Okbuysen PC, Mathewson JL, Guerrant RL, Latimer E, Lyerly D and Ericsson CD. Evaluation of a new latex agglutination test for fecal lactoferrin in travelers' diarrhea. J Travel Med 1(2):68-71, 1994.
268. Zu S-X, Li J-F, Barrett LJ, Fayer R, Shu S-Y, McAuliffe JF, Roche JK and Guerrant RL. SeroEpiogic study of Cryptosporidium infection in children from rural communities of Anhui, China and Fortaleza, Brazil. Am J Trop Med Hyg 51(1):1-10, 1994.
269. Guerrant RL. Twelve messages from enteric infections for science and society. Am J Trop Med Hyg 51(1):26-35, 1994.
270. Wuhib T, Silva TMJ, Newman RD, Garcia LS, Pereira MLD, Chaves CS, Wahlquist SP, Bryan RT, Guerrant RL, Sousa AQ, Queiroz TRBS, Sears CL. Cryptosporidial and microsporidial infections in human immunodeficiency virus-infected patients in Northeastern Brazil. J Infect Dis 170(2):494-497, 1994.
271. Guerrant RL, Fang GD, Thielman NM, Fonteles MC. Role of platelet activating factor in the intestinal epithelial secretory and Chinese hamster ovary cell cytoskeletal responses to cholera toxin. Proc Natl Acad Sci USA 91:9655-9658, 1994.
272. Guerrant RL, Martins CAP, Silva T. Fecal lactoferrin as a marker of fecal leukocytes. J Clin Microbiol 32(10):2629-2630, 1994.
273. Pickering LK, Guerrant RL, Cleary TG. Microorganisms responsible for neonatal diarrhea. In: Infectious Diseases of the Fetus and Newborn Infant, 4th Edition, Chapter 31. Remington JS, Klein JO, Editors. W.B. Saunders Company, pp 1142-1222, 1994.
274. Guerrant RL. Advances and scourges in gastrointestinal infections. Curr Opin Infect Dis 7:575-576, 1994.
275. Miller JR, Barrett LJ, Kotloff K and Guerrant RL. A rapid test for infectious and inflammatory enteritis. Arch Intern Med 154:2660-2664, 1994.
276. Guerrant RL. Principles and Syndromes of Enteric Infections. In Principles and Practice of Infectious Diseases, 4th Edition, Chapter 75, pp 945-962. Mandell, Bennett and Dolin, editors. Churchill Livingstone Inc., New York, 1994.
277. Guerrant RL and Bobak DM. Nausea, Vomiting and Noninflammatory Diarrhea. In: Principles and Practice of Infectious Diseases, 4th Edition, Chapter 77, pp 965-978. ed. by Mandell, Bennett and Dolin, Churchill Livingstone Inc., New York, 1994.
278. Guerrant RL. Inflammatory Enteritides. In Principles and Practice of Infectious Diseases, 4th Edition, Chapter 79, pp 987-998. ed. by Mandell, Bennett and Dolin, Churchill Livingstone Inc., New York, 1994.
279. Pearson RD and Guerrant RL. Enteric Fever and other Causes of Abdominal Symptoms with fever. In: Principles and Practice of Infectious Diseases, 4th Edition. Chapter 80, pp 998-1012. ed by Mandell, Bennett and Dolin, Churchill Livingstone Inc., New York, 1994.
280. Wanke CA and Guerrant RL. Tropical Sprue. In: Principles and Practice of Infectious Diseases, 4th Edition, Chapter 82, pp 1025-1030, ed. Mandell, Bennett and Dolin, Churchill Livingstone Inc., New York, 1994.
281. Planchon SM, Martins CAP, Guerrant RL, Roche JK. Regulation of intestinal epithelial barrier function by TGF-ß: Evidence for its role in abrogating the effect of a T cell cytokine. J Immun 153(12):5730?5739, 1994.
282. Fonteles MC, Fang GD, Thielman NM, Yotseff P, Guerrant RL. Role of platelet activating factor in the inflammatory and secretory effects of Clostridium difficile toxin A. J Lipid Mediators 11:133-143, 1995.
283. Thielman NM and Guerrant RL. Clostridium difficile. In: Gellis and Kagan's Burrent Pediatric Therapy. 15th edition. Burg FD, Ingelfinger JR, Wald ER and Polin RA, Editors. WB Saunders, pp 584?585, 1995.
284. Crane JK and Guerrant RL. Acute, watery diarrhea. In: Infections of the Gastrointestinal Tract, Chapter 21, pp 283-298. Blaser MJ, Smith PD, Ravdin JI, Greenberg HB, and Guerrant RL, editors. Raven Press, New York, 1995.
285. Sears CL, Kaper JB and Guerrant RL. Bacterial toxins. In: Infections of the Gastrointestinal Tract, Chapter 44, pp 617-634. Blaser MJ, Smith PD, Ravdin JI, Greenberg HB, and Guerrant RL, editors. Raven Press, New York, 1995.
286. Guerrant RL and Thielman NM. Types of Escherichia coli Enteropathogens. In: Infections of the Gastrointestinal Tract, Chapter 48, pp 687-690. Blaser MJ, Smith PD, Ravdin JI, Greenberg HB and Guerrant RL, editors. Raven Press, New York, 1995.
287. Adal K, Sterling CR and Guerrant RL. Cryptosporidium and related species. In: Infections of the Gastrointestinal Tract, Chapter 72, pp 1107-1128. Blaser MJ, Smith PD, Ravdin JI, Greenberg HB, and Guerrant RL, editors. Raven Press, New York, 1995.
288. Lima AAM, Lima NL, Pinho MCN, Barros (Jr) EA, Teixeria MJ, Martins MCV and Guerrant RL. Shigellosis in Northeastern Brazil, 1988-1993: High frequency of strains multipy resistance to ampicillin, trimethroprim-sulfamethoxazole, streptomycin, chloramphenical and tetracycline. Antimicrobial Agents and Chemotherapy 39(1):256-259, 1995.
289. Fang G, Lima AAM, Martins CV, Nataro JP and Guerrant RL. Etiology and Epidemiology of persistent diarrhea in Northeastern Brazil: a hospital-based, prospective, case-control study. J Ped Gastro Nutr 21(2):137-144, 1995.
290. Martins CAP, Fonteles MG, Barrett LJ and Guerrant RL. Correlation of lactoferrin with neutrophilic inflammation in body fluids. Clinical and Diagnostic Laboratory Immunology 2(6):763-765, 1995.
291. Schleupner MA, Garner DC, Sosnowski KM, Schleupner CJ, Barrett LJ, Silva E, Hirsch D and Guerrant RL. Concurrence of Clostridium difficile toxin A enzyme-linked immunosorbent assay, fecal lactoferrin and clinical criteria with C. difficile cytotoxin titer in two patient cohorts. J Clin Microbiol 33(7):1755-1759, 1995.
292. Martins CAP and Guerrant RL. Cryptosporidium and Cryptosporidiosis. Parasitology Today 11(11):434-436, 1995.
293. Fang GD, Lima AAM, Thielman NM, Fonteles MC, Yotseff P, Lyerly D, Guerrant RL. Role of phospholipase A2 in the histologic, epithelial and secretory responses to Clostridium difficile toxin A. Biomed J 1:71-76, 1995.
294. Guerrant RL and Theno DM. Escherichia coli 0157:H7. N Engl J Med 333(25):1711-1712, 1995.
295. Thielman NM and Guerrant RL. Acute infectious diarrhea. In: Conn's Current Therapy, 1995 ed. Rakel RE, Editor. WB Saunders, pp 9-16, 1995.
296. Petri WA JR, Hill DR and Guerrant RL. Protozoan Diseases. In: Textbook of Gastroenterology, 2nd edition, Chapter 104, pp2343-2361. Yamada T et al., Editors. JB Lippincott Co, 1995.
297. Jernigan J, Guerrant RL and Pearson RD. Parasitic infections of the small intestine. In: Gastrointestinal Problems from the Tropics CG Cook (ed.), BMJ Publishing Group, London, pp 25-39, 1995.
298. Thielman NM and Guerrant RL. Clostridium difficle and its toxins. In: Bacterial Toxins and Virulence Factors in Disease, Moss J, Iglewski B, Vaughn M, and Tu AT, Editors. Marcel Dekker, 1995.
299. Thielman NM and Guerrant RL. Sexually transmitted enteric infections. In: Current Therapy of Infectious Diseases, Schlossberg D, Editor. Mosby Year Book, pp 154-157, 1996.
300. Pearson RD, Petri WA JR, and Guerrant RL. Parasitic Diseases: helminths. In: Textbook of Gastroenterology, 2nd edition, Chapter 104, pp2362-2379. Yamada T et al., Editors. JB Lippincott Co, 1996.
301. Choi SW, Choong HP, Silva TMJ, Zaenker EI and Guerrant RL. To culture or not to culture: Fecal lactoferrin screening for inflammatory bacterial diarrhea. J Clin Microbiol 34(4):928-932, 1996. (See Letters #7).
302. Thielman NM and Guerrant RL. Food-borne illness. In: Conn's Current Therapy, 1995 ed. Rakel RE, Editor. WB Saunders, pp 89-96, 1996.
303. McAuliffe JF, Lima NL and Guerrant RL. Patterns of morbidity in childhood in Northeastern Brazil. Chapter 3 in At the Edge of Development: Health Crises in a Transitional Society, Guerrant RL, Nations MK, de Souza MA, Editors. Carolina Academic Press, pp 53-68, 1996.
304. Guerrant RL, McAuliffe JF and de Souza MA. Mortality among urban and rural families: An indicator of development and implications for the future. Chapter 4 in At the Edge of Development: Health Crises in a Transitional Society, Guerrant RL, Nations MK, de Souza MA, Editors. Carolina Academic Press, pp 69-88, 1996.
305. Guerrant RL, Lima NL and Sears CL. Etiologies and Epidemiology of childhood diarrhea in Brazil's Northeast. Chapter 5 in At the Edge of Development: Health Crises in a Transitional Society, Guerrant RL, Nations MK, de Souza MA, Editors. Carolina Academic Press, pp 91-108, 1996.
306. Lima AAM, Khin-Maung-U and Guerrant RL. The physiologic basis for oral rehydration therapy and its improvements. Chapter 6 of At the Edge of Development: Health Crises in a Transitional Society, Guerrant RL, Nations MK, de Souza MA, Editors. Carolina Academic Press, pp 109-126, 1996.
307. Braga LL, Marshall BJ, Moreno H, Lima AAM and Meneges D, Zu S-X, Roche JK, Guerrant RL. Helicobacter pylori: Gastritis, peptic ulcer and gastric cancer in developing countries. Chapter 7 in At the Edge of Development: Health Crises in a Transitional Society, Guerrant RL, Nations MK, de Souza MA, Editors. Carolina Academic Press, pp 127-147, 1996.
308. Pennie RA, Pearson RD, McAuliffe MI and Guerrant RL. The illness burden in poor rural and urban communities: Enteric parasitic infections. Chapter 8 in At the Edge of Development: Health Crises in a Transitional Society, Guerrant RL, Nations MK, de Souza MA, Editors. Carolina Academic Press, pp 149-159, 1996.
309. Wanke CA, McAuliffe JF and Guerrant RL. Pathogenesis of persistent diarrhea. Chapter 10 in At the Edge of Development: Health Crisis in a Transitional Society, Guerrant RL, Nations MK, de Souza MA, Editors. Carolina Academic Press, pp 177-201, 1996.
310. de Sousa AQ, Evans TG, Wispelwey B and Guerrant RL. Emerging impact of AIDS in Brazil's Northeast. Chapter 14 in At the Edge of Development: Health Crises in a Transitional Society, Guerrant RL, Nations MK, de Souza MA, Editors. Carolina Academic Press, pp 263-277, 1996.
311. McAuliffe JF, Schorling JB and Guerrant RL. Diarrhea and nutritional status in Urban Northeast Brazil: interrupting the vicious cycle. Chapter 16 in At the Edge of Development; Health Crises in a Transitional Society, Guerrant RL, Nations MK, de Souza MA, Editors. Carolina Academic Press, pp 295-313, 1996.
312. Guerrant RL, Kirchhoff LV, Shields DS, Hook EW, de Souza MA and Hughes JM. Health impacts of household water quality and availability. Chapter 17 in At the Edge of Development: Health Crises in a Transitional Society, Guerrant RL, Nations MK, de Souza MA, Editors. Carolina Academic Press, pp 317-333, 1996.
313. Schorling J and Guerrant RL. Antibiotic use among children in Goncalves Dias: Epidemiology, risk factors and consequences. Chapter 19 in At the Edge of Development: Health Crises in a Transitional Society, Guerrant RL, Nations MK, de Souza MA, Editors. Carolina Academic Press, pp 263-377, 1996.
314. Guerrant RL. Realizing the potential development holds for health and the human condition: Integration of biomedical understanding with practice. Chapter 22 in At the Edge of Development: Health Crises in a Transitional Society, Guerrant RL, Nations MK, de Souza MA, Editors. Carolina Academic Press, pp 431-442, 1996.
315. Silva TM, Schleupner MA, Tacket CO, Steiner TS, Kaper JB, Edelman R and Guerrant RL. New evidence for an inflammatory component in diarrhea caused by selected new, live attenuated cholera vaccines and by El Tor and O139 Vibrio cholerae. Infect Immun 64(6):2362-2364, 1996.
316. Steiner TS and Guerrant RL. The pathogenesis of and host response to Cryptosporidium parvum. Current Opinion in Infectious Diseases 9:156-160, 1996.
317. Walser BL, Lima AAM and Guerrant RL. Effects of high-dose oral vitamin A on diarrheal episodes among children with persistent diarrhea in a Northeast Brazilian community. Am J Trop Med Hyg 54(6):582-585, 1996.
318. Huicho L, Campos M, Rivera J and Guerrant RL. Fecal screening tests in the approach to acute infectious diarrhea: A scientific overview. Pediatr Infect Dis J 15(6):486-494,1996.
319. Santosham M, Thielman M and Guerrant RL. Management of acute gastroentreitis in young children. Abstracts of Clinical Care Guidelines 8(7):7-11, 1996.
320. Lang DR and Guerrant RL. Summary of the 31st United States-Japan joint conference on cholera and related diarrheal diseases. J Infect Dis 174:451-455, 1996.
321. Bao Y, Silva TMJ, Guerrant RL, Lima AAM and Fox JW. Direct analysis of mannitol, lactulose and glucose in urine samples by high performance amion-exchange chromatography with pulse ampersometric detection: clinical evaluation of intestinal permeability in human immunodeficiency virus infection. J Chromatog B, Biomedical Appl 685:105-112, 1996.
322. Rein MF, Shih LM, Miller JR and Guerrant RL. Use of a lactoferrin assay in the differential diagnosis of female genital tract infections and implications for the pathophysiology of bacterial vaginosis. Sexually Transmitted Diseases. 23:517-21, 1996.
323. Braga LL, Lima AAM, Sears CL, Newman RD, Wuhib T, Paiva CA, Guerrant RL and Mann BJ. SeroEpidemiology of Entamoeba histolytica in a slum in northeastern Brazil. Am J Trop Med Hgy 55(6): 693-697, 1996.
324. Wanke CA and Guerrant RL. Infectious gastroenteritis. In Medicine for the Practicing Physician. Hurst, JW, Editor. Appleton and Lange, 1996.
325. Guerrant RL, Sears CS and Ravdin JI. Intestinal Protozoa: Giardia lamblia, Entamoeba histolytica, and Cryptosporidium. In: Sexually Transmitted Diseases, 3rd Edition, Chapter 44, pp - Holmes KK, Mardh P, Sparling PF and Wiesner PJ, Editors. McGraw Hill, New York, NY, 1997.
326. Thielman NM and Guerrant RL. Escherichia coli. In: Principles and Practices of Clinical Bacteriology. Emmerson AM, Hawkey PM and Gillespie SH, Editors. John Wiley & Sons Ltd,, pp 373-388, 1997.
327. Steiner TS, Thielman NM and Guerrant RL. Protozoal agents: What are the dangers for the public water supply? Ann Rev Med 48:329-340, 1997.
328. Guerrant RL, Lima AAM, Thielman NM, Steiner TS and Fonteles MC. Diarrhea, demography and cell signaling: lessons from microbial toxins. Transactions of the American Clinical and Climatological Association 108:149-164, 1997.
329. Thielman NM, Fang GD, Guerrant RL. Role of platelet activating factor in Chinese hamster ovary cell responses to cholera toxin. J Clin Invest 99(No 8): 1999-2004, 1997.
330. Guerrant RL. Cryptosporidiosis: An emerging highly infectious threat. Emerg Infect Dis, 3(1):51-57, 1997.
331. Koopmans MPG, Goosen ESM, Lima AAM, McAuliffe IT, Nataro JP, Barrett LJ, Glass RI and Guerrant RL. Association of torovirus with acute and persistent diarrhea in children. Ped Infect Dis J, 16(5):504-507, 1997.
332. Rocha MFG, Maia MET, Bezerra LRPS, Lyerly DM, Guerrant RL, Ribeiro RA and Lima AAM. Clostridium difficile toxin A induces the release of neutrophil chemotactic factors from rat peritoneal macrophages: Role of interleukin-1, tumor necrosis factor alpha, and leukotrienes. Infect Immun 65(7): 2740-2746, 1997.
333. Steiner TS and Guerrant RL. Infections of the colon. In: Gastrointestinal Pharmacology and Therapeutics, Chapter 22, pp 249-265 Friedman G, Jacobson ED, McCallum RW, editors, Lippincott-Raven Publishers, Philadelphia, 1997.
334. Watanabe H and Guerrant RL Summary: Nagasaki enterohemorrhagic Escherichia coli meeting and workshop. J Infect Dis 176:247-249, 1997.
335. Thielman NM and Guerrant RL. An algorithmic approach to the workup and management of HIV-related diarrhea. Journal of Clinical Outcomes Management 4(No. 2): 36-47, 1997.
336. Thielman NM and Guerrant RL. Pathophysiology of gastrointestinal infections: host defenses versus microbial virulence traits. In: Gastrointestinal Pharmacology, Chapter 19, pp 193-200 Friedman G, Jacobson ED, McCallum RW, editors, Lippincott-Raven Publishers, Philadelphia, 1997.
337. Iida T, Naka A, Suthienkul O, Sakaue Y, Guerrant RL and Honda T. Measurement of fecal lactoferrin for rapid diagnosis of enterohemorrhagic Escherichia coli infection. Clin Infec Dis, 25:167, 1997.
338. Guerrant RL. Bacterial enteritis. In: Infectious Diseases Teaching Atlas. Lorber B, Editor, 1997.
339. Guerrant RL and Thielman NM. Emerging enteric protozoa: Cryptosporidium, Cyclospora and microsporidia. In: Emerging Infections I,Scheld WM and Armstrond D, eds. Chapter 16, pp.233-245, 1997.
340. Lima AAM, Silva TMJ, Gifoni AMR, Barrett LJ, McAuliffe IT, Bao Y, Fox JW, Fedorko DP and Guerrant RL. Mucosal injury and disruption of intestinal barrier function in HIV-infected individuals with and without diarrhea and cryptosporidiosis in Northeast Brazil. Am J Gastroent, 92:1861-1866, 1997.
341. Huicho L, Garaycochea V, Uchima N, Zerpa R and Guerrant RL. Fecal lactoferrin, fecal leukocytes and occult blood in the diagnostic approach to childhood invasive diarrhea. Pediatr Infect Dis J 16:644-647, 1997.
342. Steiner TS, Flores CA, Pizarro TT and Guerrant RL. Fecal lactoferrin, Interleukin-1 , and Interleukin-8 are elevated in patients with severe Clostridium difficile colitis. Clin and Diag Lab Immunol, 4(6):719-722, 1997.
343. Thielman NM and Guerrant RL. Infectious Diarrhea. In: Essentials of Infectious Diseases. Cunha, editor 1997.
344. Steiner TS, Lima AAM, Nataro JP and Guerrant RL. Enteroaggregative Escherichia coli produce intestinal inflammation and growth impairment and cause interleukin-8 release from intestinal epithelial cells. J Infect Dis ,177:88-96, 1998.
345. Guerrant RL, Pearson RD and Lee B. Tropical diseases and geographic medicine. Chapt. 20 in International, Occupational and Environmental Medicine. Bunn, Fleming, Gardner, Harrington, Herzstein and Jeyaratnam, eds. Mosby, St. Louis, pp 223?241, 1998.
346. Agnew DG, Lima AAM, Newman RD, Wuhib T, Moore RD, Guerrant RL and Sears CL. Cryptosporidiosis in northeastern Brazilian children: Association with increased diarrheal morbidity. J Infect Dis, 177:754-760,1998.
347. Wilson ME, Lima AAM and Guerrant RL. Infections caused by Vibrio species. In: Internal Medicine, Fifth Edition. Stein et al., Editors. Mosby-Year Book, Inc., St. Louis, Chapter 268, pp1593-1598, 1998.
348. Silva AC, Santos-Neto MS, Soares AM, Fonteles MC, Guerrant RL and Lima AAM. Efficacy of a glutamine-based oral rehydration solution on the electrolyte and water absorption in a rabbit model of secretory diarrhea induced by choleratoxin. J Ped Gastroenterol Nutr, 26:513?519, 1998. (with accompanying editorial--Duggan C. Glutamine-based oral rehydration solutions: the magic bullet revisited? [editorial; comment]. Journal of Pediatric Gastroenterology & Nutrition 1998;26:533-535.)
349. Thielman NM and Guerrant RL. Persistent diarrhea in the returned traveler. In: Infectious Disease Clinics of North America:Travel Medicine. Freedman DO, ed. W.B. Saunders, Philadelphia. 12(2):489?501,1998.
350. Guerrant RL. Why America must care about tropical medicine: Threats to global health and security from tropical infectious diseases. Am Trop Med Hyg 59(1):3?16, 1998.
351. Jin X-H, Wang Z-Q, Siragy HM, Guerrant RL and Carey RM. Regulation of jejunal sodium and water absorption by antiotensin subtype receptors. Am J Physiol 44:R515?R523 1998.
352. Fine KD, Ogunji F, George J, Niehaus MD and Guerrant RL. Utility of a rapid fecal latex agglutination test detecting the neutrophil protein lactoferrin for diagnosing inflammatory causes of chronic diarrhea. Am J Gastro, 93(8):1300?1305, 1998.
353. Rocha MFG, Soares AM, Flores CA, Steiner TS, Lyerly DM, Guerrant RL, Ribeiro RA and Lima AAM. Intestinal secretory factor released by macrophages stimulated with Clostridium difficile toxin A: Role of interleuken 1?. Infect and Immun 66(10):4910?4916, 1998.
354. Thielman NM and Guerrant RL. Escherichia coli. In Antimicrobial Chemotherapy Yu V, Merigan T and Barriere S, eds. Williams and Wilkins, Baltimore, pp 188?200, 1998.
355. Nataro JP, Steiner TS and Guerrant RL. Enteroaggregative Escherichia coli (EAEC): an emerging cause of diarrhea and malnutrition. Emerging Infectious Diseases, 4(2):251?261, 1998.
356. Jernigan JA, Siegman-Igra Y, Guerrant R(L) and Farr BM. A randomized crossover study of disposible thermometers for prevention of Clostridium difficile and other nosocomial infections, Infect Contr & Hosp Epidemiol, 19(7):494-499, 1998.
357. Guerrant RL and Crane JK. Chapter on Gram-Negative Bacilli Infections. In: The Merck Manual for nonmedical persons, West Point, PA, press, 1998.
358. Guerrant RL, Steiner TS., Lima AAM, and Bobak DA. How intestinal bacteria cause disease. JID 179(2):S331-S337, 1999.
359. Guerrant RL and Blackwood BL. Threats to global health and survival: The growing crises of tropical infectious diseases--Our "unfinished agenda." CID 28:966-86, 1999.
360. Newman RD, Sears CL, Moore SR, Nataro JP, Wuhib T Agnew DA, Guerrant RL and Lima AAM. Longitudinal study of Cryptosporidium infection in children in Northeastern Brazil. JID 180:167-175, 1999.
361. Guerrant RL. Campylobacter enteritis. In: Cecil Textbook of Medicine - 21th Edition, Goldman, L and Bennett JC , Editors. pp 1687 1690, 1999.
362. Guerrant RL. Enteric Escherichia coli infections. In: Cecil Textbook of Medicine - 21th Edition, Goldman L and Bennett JC, Editors. pp 1693 1696, 1999.
363. Guerrant DI, Moore SR, Lima AAM, Patrick P, Schorling JB and Guerrant RL. Association of early childhood diarrhea and cryptosporidiosis with impaired physical fitness and cognitive function four--seven years later in a poor urban community in Northeast Brazil. Am J Trop Med Hyg 61(5):707 713, 1999.
364. Guerrant RL, Lima AAM, Barboza M, Young S, Silva T, Barrett L, Bao Y, Fox J and Moore S. Mechanisms and Impact of Enteric Infections. (Proceedings of the 2nd International Rushmore Conference on Mechanisms in the Pathogenesis of Enteric Diseases) Mechanisms in the Pathogenesis of Enteric Diseases 2. Paul PS and Francis DH, Editors. Advances in Experimental Medicine and Biology 473:103 11, 1999.
365. Pearson RD, Weller PF and Guerrant RL. Chemotherapy of parasitic diseases. In: Tropical Infectious Diseases: Principles, Pathogens and Practice, Guerrant, Walker and Weller, Editors. Churchill Livingstone, Philadelphia, pp 215-237, 1999.
366. Thielman NM and Guerrant RL. Enteric Escherichia coli infections in Tropical Infectious Diseases: Principles, Pathogens and Practice, Guerrant, Walker and Weller, Editors. Churchill Livingstone, Philadelphia, pp 261-276, 1999.
367. Steiner TS, Pape JW and Guerrant RL. Intestinal coccidial Infections. In: Tropical Infectious Diseases: Principles, Pathogens and Practice, Guerrant, Walker and Weller, Editors. Churchill Livingstone, Phildelphia, pp 721-735, 1999.
368. Barboza Jr. MS, Silva TMJ, Guerrant RL and Lima AAM. Measurement of intestinal permeability using mannitol and lactulose in children with diarrheal diseases. Bras J Med Biol Res 32:1499-1504, 1999.
369. Jin X-H, Siragy HM, Guerrant RL and Carey RM. Compartmentalization of extracellular cGMP determines absorptive or secretory responses in the rat jejunum. J Clin Invest 103(2):167-174, 1999.
370. Parks CG, Moe CL, Rhodes D, Lima A, Barrett L, Tseng FC, Baric R, Talal A, and Guerrant RL. Genomic diversity of Norwalk-like viruses" (NLBs): Pediatric infections in a Brazilian shantytown. J Med Virol, 58:426-439, 1999.
371. Guerrant RL and Crane JK. Chapters on Enterobacteriaceae, Infections, Brucellosis, and Tularemia, and. In: The Merck Manual, Edition 17, West Point, PA, 1999.
372. Guerrant RL and Lima AAM. Cholera. In Advances in Medicine edited by RF Edlich, pub. By Vandemere,1999
373. Guerrant RL, Moore SR, Lima AAM. Safe drinking water: An attainable goal, key to health and development, appears farther away. Int J Infect Dis, 4(1): 1 2, 2000.
374. Talal AH, Moe CL, Lima AAM, Weigle KA, Barrett L, Bangdiwala SI, Estes MK and Guerrant RL. Seroprevalence and seroincidence of Norwalk-like virus infection among Brazilian infants and children. J Med Virol, 61:117-124, 2000.
375. Lima AAM, Moore SR, Barboza Jr. MS, Soares AM, Schleupner MA, Newman RD, Sears CL, Nataro JP, Fedorko DP, Wuhib T, Schorling JB and Guerrant RL. Persistent diarrhea signals a critical period of increased diarrhea burdens and nutritional shortfalls: A prospective cohort study among children in Northeastern Brazil. J Infec Dis, 181:1643-1651, 2000.
376. Niehaus MD, Gwaltney Jr. JM, Hendley JO, Newman MJ, Heymann PW, Rakes GP, Platts-Mills TAE and Guerrant RL. Lactoferrin and eosinophilic cationic protein in nasal secretions of patients with experimental rhinovirus colds, natural colds, and presumed acute community-acquired bacterial sinusitis. J Clin Microbiol 38(8):3100-3102, 2000.
377. Quadro L, Gamble MV, Vogel S, Lima AAM, Plantedost R, Moore SR, Colantuoni V, Gottesman ME, Guerrant RL and Blaner WS. Retinol and retinol-binding protein: Gut integrity and circulating immunoglobulins. J Infect Dis 182(Suppl 1):S97-102, 2000.
378. Guerrant RL, Lima AAM and Davidson F. Micronutrients and infection: Interactions and implications with enteric and other infections and future priorities. J Infect Dis 182(Suppl 1):S134-138, 2000.
379. Roche JK, Martins CAP, Cosma R, Fayer R. and Guerrant RL. Transforming growth factor ß1 ameliorates intestinal epithelial barrier disruption by Cryptosporidium parvum in vitro in the absence of mucosal T lymphocytes. Infect and Immun 68(10):5635-5644, 2000.
380. Steiner TS, Nataro JP, Poteet-Smith CE, Smith JA, and Guerrant RL. Enteroaggregative Escherichia coli expresses a novel flagellin that causes IL-8 release from intestinal epithelial cells. J Clin Invest 105(12):1769-1777, 2000.
381. Alcantara CS and Guerrant RL. Update on Clostridium difficile infection. Current Gastroenterology Reports, 2:1-5, 2000.
382. Goldenberg RL, Andrews WW, Guerrant RL, Newman M, Mercer B, Iams J, Meis P, Moawad A, Das A, VanDorsten JP Caritis SN, Thurnau G, Bottoms S, Miodovnik M, McNellis D and Roberts JM. The preterm prediction study: Cervical lactoferrin concentration, other markers of lower genital tract infection, and preterm birth. National Institute of Child Health and Human Development Maternal-Fetal Medicine Units Network. Am J Obstet Gynecol 182(3):631-635, 2000.
383. Rocha MF, Sidrim JJ, Soares AM, Jimenez GC, Guerrant RL, Ribeiro RA and Lima AAM. Supernatants from macrophages stimulated with microcystin-LR induce electrogenic intestinal response in rabbit ileum. Pharmacol Toxicol, 87(1):46-51, 2000.
384. Moore SR, Lima AAM, Schorling JB, Barboza Jr. MS, Soares AM, Guerrant RL. Changes over time in the epidemiology of diarrhea and malnutrition among children in an urban Brazilian shantytown, 1989 to 1996. Int J Infect Dis, 4(4):179-186, 2000.
385. Guerrant RL. The Unacceptable Costs of the Diseases of Poverty: Four E's that Threaten Us All. Editorial commentary, Current Infectious Disease Reports 3:1-3, 2001.
386. Guerrant RL, Gilder TV, Steiner TS, Thielman NM, Slutsker L, Tauxe RV, Hennessy T, Griffin PM, DuPont H, Sack RB, Tarr P, Neill M, Nachamkin I, Reller BL, Osterholm MT, Bennish ML and Pickering LK. Practice guidelines for the management of Infectious Diarrhea. Clin Infect Dis 32:331-350, 2001.
387. Guerrant RL, Kosek M. Polysaccharide conjugate typhoid vaccine. N Eng J Med 344(17):1322-1323 ,2001.
388. Ciesla WP, and Guerrant RL. Infectious diarrhea in Current Diagnosis & Treatment of Infectious Disease ed. Wilson W.R. & Sande M.A., McGraw Hill, New York, Ch 20, pp255-268, 2001.
389. Blikslager A., Hunt E., Guerrant R., Rhoads M., and Argenzio R. Glutamine transporter in crypts compensates for loss of villus absorption in bovine cryptosporidiosis, Am. J. Physiol. Gastrointest. Liver Physiol, 281(3):G645-G653, 2001.
390. Alcantara C, Stenson WF, Steiner T.S. and Guerrant RL. Role of inducible cyclooxygenase and prostaglandins in Clostridium difficile Toxin A-induced secretion and inflammation in an animal model. J. Infect. Dis. 184:648-52, 2001.
391. Newman RD, Moore SR, Lima AAM, Nataro JP, Guerrant RL and Sears CL. A longitudinal study of Giardia lamblia infection in Northeast Brazilian children. Trop. Med. Int. Health 6(8) 624-634, 2001.
392. Kosek M., Alcantara C, Lima AAM, and Guerrant.RL. Cryptosporidiosis: An Update. The Lancet Infectious Diseases. 1(4):262-269, 2001.
393. Moore SR, Lima AAM, Conaway MR, Schorling JB, Soares AM, Guerrant RL. Early childhood diarrhea and helminthiases associate with long-term linear growth faltering. Int J Epidemiol, 30:1457-1464, 2001.
394. Kosek M and Guerrant RL. Traveler's diarrhea. PIER module: Clinician's Handbook of Preventive Services, 2nd ed., 2001.
395. Byers KE, Guerrant RL and Farr BM. Fecal-oral transmission. In "Epidemiologic Methods for the Study of Infection Diseases." Thomas, JC and Weber, DJ, editors. J Oxford University Press, pp228-248, 2001.
396. Huston C, Guerrant RL. Intestinal Protozoa (chapter 98)vol.(2)7thed. 1933-1950 Gastrointestinal and Liver Disease. Ed., Feldman M, Friedman LS, Sleisenger MH, 2002.
397. Brito GAC, Sullivan GW, Ciesla, Jr. WP, Carper HT, Mandell GL and Guerrant RL. Clostridium difficile Toxin A alters in vitro-adherent neutrophil morphology and function. J Infect Dis 85:1297-1306, 2002
398. Guerrant RL, Kosek M, Lima AAM, Lorntz L and Guyatt H. Updating the DALYs for diarrhoeal disease. Trends in Parasitology. 18(5):191-193, 2002.
399. Lima AAM, Carvalho GHP, Figueiredo AA, Gifoni AR, Soares AM, Silva AT and Guerrant RL. Effects of an alanyl-glutamine-based oral rehydration and nutrition therapy solution on electrolyte and water absorption in a rat model of secretory diarrhea induced by cholera toxin. Nutri. 18(6):458-462, 2002.
400. Guerrant RL. The Unacceptable Costs of the Diseases of Poverty. The Virginia News Letter, Weldon Cooper Center for Public Service, vol 78, No 3, pp 1-5. May, 2002.
401. Thielman NM, Rust PF and Guerrant RL. Criterion-related validity of a diarrhea questionnaire in HIV-infected patients. Digestive Diseases and Sciences 47(7):1421-1426, 2002.
402. Cheng,A.C., Thielman, N.M. and Guerrant, R.L. "Escherichia coli". Antimicrobial Therapy And Vaccines, Apple Tree Productions, LLC. New York, NY, I (2): 285-300. 2002
403. Niehaus MD, Moore SR, Patrick PD, Derr LL, Lorntz,B, Lima AA, and Guerrant RL. Early childhood diarrhea is associated with diminished cognitive function 4-7 years later in children in a northeast Brazilian shantytown. Am J Trop Med Hyg, 66(5), 590-593, 2002.
404. Guerrant RL, Kosek M, Moore S, Lorntz B, Brantley R and Lima AAM. Magnitude and Impact of Diarrheal Diseases, Archives of Medical Research, 33:351-355, 2002
405. Dillingham RA, Lima AA and Guerrant RL. Cryptosporidiosis: Epidemiology and Impact. Microbes and Infection, 4:1059-1066, 2002
406. Brito GAC, Fujji J, Carneiro-Filho BA, Lima AAM, Obrig T and Guerrant RL. Mechanism of Clostridium difficile Toxin A-Induced Apoptosis in T84 cells. J Infect Dis, 186:1438-1447 2002.
407. Dourado ME, Duarte RC, Ferreira LC, Queiroz JW, Illa I, Perez-Perez G, Guerrant RL, Jeronimo SMB. Anti-ganglioside antibodies and clinical outcome of patients with Guillan-Barre Syndrome in northeast Brazil, Acta Neurol Scand, 108:102-108, 2003.
408. Kosek M, Bern C, and Guerrant RL. The Global Burden of Diarrhoeal Disease, as estimated from studies published between 1992--2000. Bull WHO, 81 (3): 197-204, 2003.
409. Alcantara CS, Yang C-H, Steiner TS, Barrett LJ, Lima AAM, Chappell CL, Okhuysen PC, White AC, Jr., and Guerrant RL. Interleukin-8, Tumor Necrosis Factor-?, and Lactoferrin In Immunocompetent Hosts with Experimental and Brazilian Children with Acquired Cryptosporidiosis. Am J Trop Med Hyg, 68 (3): 325-328, 2003.
410. Carneiro-Filho BA, Bushen OY, Brito GAC, Lima AAM, Guerrant RL. Glutamine analogues as adjunctive therapy for infectious diarrhea. Curr Infect Dis Rep, 5(2): 114-119, 2003.
411. Bushen OY, Guerrant RL. Acute Infectious Diarrhea: Approach and Management in the Emergency Department. Trop Emerg Med 25 (2): 142-152, 2003.
412. Mitchell A, Silva TMJ, Barrett LJ, Lima AAM, Guerrant RL. Age-specific Helicobacter pylori seropositivity rates in children in an impoverished urban area of Northeast Brazil. J Clin Microbiol 41 (3): 1326-1328, 2003.
413. Brantley RK, Williams KR, Silva TMJ, Sistrom M, Thielman NM, Ward H, Lima AAM, and Guerrant RL. AIDS-associated diarrhea and wasting in Northeast Brazil is associated with subtherapeutic plasma levels of antiretroviral medications and with both bovine and human subtypes of Cryptosporidium parvum. Braz J Infect Dis. 7(1):16-22, 2003.
414. Guerrant RL, Carneiro-Filho BA, Dillingham R. Cholera, diarrhea and oral rehydration therapy: triumph and indictment. Clin Infect Dis. 37(3):398-405, 2003.
415. Castro MX, Soares AM, Fonseca W, Rey LC, Guerrant RL and Lima AAM. Common infectious diseases and skin test anergy in children from an urban slum in northeast Brazil. Braz J Infect Dis. 7(6):387-394, 2003.
416. Guerrant RL. Campylobacter enteritis. In: Cecil Textbook of Medicine - 22nd Edition, Ch 327, pp 1855-1858. Sanders; Harcourt Health Sciences. Philadelphia, 2004.
417. Guerrant RL. Enteric Escherichia coli infections. In: Cecil Textbook of Medicine - 22th Edition Ch 329, pp 1861-1864. Sanders; Harcourt Health Sciences. Philadelphia, 2004.
418. Thielman NM and Guerrant RL. Acute infectious diarrhea. N Engl J Med 350:38-47, 2004.
419. Dillingham R and Guerrant RL. Childhood stunting: measuring and stemming the staggering costs of inadequate water and sanitation. Lancet. 363: 94-5, Jan 10, 2004.
420. Lima AAM and Guerrant RL. Strategies to reduce the devastating costs of early childhood diarrhea and its potential long-term impact: Imperatives that we can no longer afford to ignore. Commentary. Clin Infect Dis 38: 1552-1554, 2004.
421. Chen P, Soares AM, Lima AAM, Gamble MV, Schorling JB, Conaway M, Barrett LJ, Blaner WS and Guerrant RL. Association of vitamin A and zinc status with intestinal permeability and linear growth: Analyses of cohort data from Northeast Brazil. J. Health, Pop Nutr. 21: 309-315, 2003.
422. Carneiro-Filho BA, Oria RB, Rea KW, Brito GAC, Fugii J, Obrig T, Lima AAM, Guerrant RL. Alanyl-glutamine hastens morphological recovery from 5-Fluorouracil induced mucositis in mice. Nutrition 20:934-941, 2004.
423. Bushen OY, Piscitelli SC, Pharm D, Uzgiris AJ, Davenport JA, Bezerra A, Silva TMJ, Leite RD, Mosek M, Dillingham R., Girao A, Lima AA, Guerrant RL. Diarrhea and reduced antiretroviral drug levels: Improvement with glutamine or alanyl-glutamine in a randomized controlled trial in northeast Brazil. Clin Infect Dis 38:1764-70, 2004.
424. Destura RV, Labio ED, Barrett LJ, Alcantara CS, Gloria VI, Daez ML, Guerrant RL. Laboratory diagnosis and susceptibility profile of Helicobacter pylori infection in the Philippines.
Ann Clin Microbiol Antimicrob. 2004 Nov 16;3(1):25.
425. Lima AAM, Brito LFB, Ribeiro HB, Martins MCV, Lustosa AP, Rocha EM, Ashworth AH, Lima NL, Monte CMG, Guerrant RL. Intestinal Barrier Function and Weight Gain in Malnourished Children Taking Glutamine Supplemented Enteral Formula. J Pediatr Gastroenterol Nutr. 2005 Jan;40(1):28-35.
426. Oriá RB, Patrick PD, Zhang H, Lorntz B, Costa CMC, Brito GAC, Barrett LJ, Lima AAM, Guerrant RL. APOE4 Protects the Cognitive Development in Children with Heavy Diarrhea Burdens in Northeast Brazil. Pediatr Res 2005;57(2):310-6.
427. Brito GA, Alcantara C, Carneiro-Filho BA, Guerrant RL. Pathophysiology and impact of enteric bacterial and protozoal infections: new approaches to therapy. Chemotherapy. 2005;51 Suppl 1:23-35.
428. Patrick P, Oria RB, Madhavan V, Pinkerton, RC, Lorntz B, Lima AAM, Guerrant RL. Limitations in Verbal Fluency Following Heavy Burdens of Early Childhood Diarrhea in Brazilian Shantytown Children. Child Neuropsychol. 2005 May:11(3):233-244.
429. Alcantara CS, Jin XH, Brito GAC, Carneiro-Filho BA, Barrett LJ, Carey RM, Guerrant RL. Angiotensin II Subtype 1 Receptor Blockade Inhibits Clostridium difficle Toxin A-Induced intestinal Secretion in a Rabbit Model JID 2005:191(12):2090-6.
430. Brito GAC, Carneiro-Filho B, Oria RB, Destura RV, Lima AAM, Guerrant RL. C. difficile toxin A induces intestinal epithelial cell apoptosis and damage: Role of glutamine and Alanyl-glutamine on toxin A effects. Digestive Diseases and Sciences, 2005 July:50(7):1271-1278.
431. Houpt ER, Bushen OY, Sam NE, Kohli A, Asgharpour A, Ng CT, Calfee DP, Guerrant RL, Maro V, Ole-Nguyaine S, Shao JF. Short Report: Asymptomatic C. hominis Infection among HIV-Infected patients in Tanzania. Am. J. Trop. Med. Hyg. 73(3), 2005, pp 520-522.
432. Nascimento SB, Sousa RB, Martins MJB, Souza MHLP, Guerrant RL, Cunha FQ, Ribeiro RA, Brito GAC. Glutamine depletion potentiates leukocyte dependent inflammatory events induced by carrageenan or C. difficile toxin A in rats. Immunology. 2005 Nov;116(3):328-36.
433. Guerrant RL, Oria R, Bushen OY, Patrick PD, Houpt E, Lima AAM. Global Effect of Diarrheal Diseases Experienced by Travelers: The Rest of the Hippopotamus. Clin Infect Dis. 2005 Dec 1;41 Suppl 8:S524-30.
434. Carneiro-Filho, BA, Brito GAC, Oria RB, Lima AAM, Guerrant, RL. Caspase and Bid involvement in Clostridium difficile Toxin A-induced apoptosis and modulation of toxin A effects by Glutamine and Alanyl-glutamine in vivo and in vitro. Infection and Immunity 74: 81-87, 2006.
435. Cavalcante IC, Castro MV, Barreto ARF, Sullivan GW, Vale M, Almeida PCR, Linden J, Rieger JM, Cunha FQ, Guerrant RL, Ribeiro RA, Brito GAC. Effect of A Novel A2A Adenosine Receptor Agonist (ATL 313) on Clostridium Difficile Toxin A-Induced Murine Ileal Enteritis. Infection and Immunity, 2006 ;74(5):2606-12.3.
436. Lorntz B, Soares AM, Moore SR, Pinkerton R, Gansneder B, Bovbjerg VE, Guyatt H, Lima AAM, Guerrant RL. Early Childhood Diarrhea Predicts Impaired School Performance. Ped Inf Dis J. 2006 ; 25(6) 513-520.
437. Guerrant RL. New England Journal of Medicine Editorial. Cholera: Still teaching hard lessons. NEJM, 354:23, 2500-2502, 2006.
438. Steiner TS, Samie A, Guerrant RL. Infectious Diarrhea: New Pathogens and New Challenges in Developed and Developing Areas. Clin Infect Dis. 2006 15;43(4):408-10.
Editorial Commentary on Nataro et al (Diarrheagenic E. coli in Baltimore and New Haven, Clin Infect Dis 2006 this issue) and Brooks et al (Surveillance for Bacterial Diarrhea and Antimicrobial Resistance in Rural Western Kenya, 1997-2003. Clin Infect Dis 2006 this issue).
439. Samie A, Obi LC, Bessong PO, Stroup SE, Houpt ER, Guerrant RL. Prevalence and Species Distribution of E. histolytica and E. Dispar in the Venda Region, Limpopo, South Africa. Am. J. Trop. Med. Hyg., 75(3), 2006, pp. 565-571.
440. Oria RB, Vieira CMG, Pinkerton, RC, Costa CMC, Lopes MB, Hussaini I, Shi W, Brito GAC, Lima AAM, Guerrant RL. Apolipoprotein E knockout mice have accentuated malnutrition with mucosal disruption and blunted insulin-like growth factor I responses to refeeding. Nutrition Research, 26 (2006) 427-435.
441. Samie A, Bessong PO, Obi CL, Sevilleja JEAD, Stroup S, Houpt E, and Guerrant RL. Cryptosporidium species: preliminary descriptions of the prevalence and genotype distribution among school children and hospital patients in the Venda region, Limpopo Province, South Africa..Experimental Parasitology 114 (2006) 314-322
442. Bushen OY, Kohli A, Pinkerton RC, Newman RD, Sears CL, Fayer R, Lima AAM, Guerrant RL. Heavy Cryptosporidial Infections in Children in Northeast Brazil: Comparison of C. hominis and C. parvum. Trans R Soc Trop Med Hyg. ( 2007) 101, 378-384.
443. Oriá RB, Patrick PD, Blackman JA, Lima AAM, Guerrant RL. Invited Commentary. Role of Apolipoprotein E4 in Protecting Children Against Early Childhood Diarrhea Outcomes and Implications for Later Development. Med Hypoth (2007) 68, 1099-1107.
444. Ricci KA, Girosi F, Tarr PI, Lim YW, Mason C, Miller M, Hughes J, von Seidlein L, Agosti JM, Guerrant RL. Reducing Stunting Among Children: The Potential Contribution of Diagnostics. Gates/Rand Corporation. Nature. 2006 Nov 23;444 Suppl 1:29-38
445. Samie A, Obi CL, Barrett LJ, Powell SM, Guerrant RL. Prevalence of Campylobacter species, Helicobacter pylori and Arcobacter species in stools samples from the Venda region, Limpopo Province, South Africa: Studies using molecular diagnostic methods. Journal of Infection. Dec 1, 2006 [Epub ahead of print]
446. Stroup SE, Roy S, Mchele J, Maro V, Ntabaguzi S, Barclay J, Guerrant RL, Kirkpatrick E, Hervein J, Ward H, Haque R, Houpt ER. Species-specific real-time PRC for Cryptosporidium in stool using Scorpion probes. J Med Microbiol. 2006 Sep;55(Pt 9):1217-22
447. Pinheiro VGF, Ramos LMA, Monteiro HSA, Barroso EC, Bushen OY, Facanha MC, Peloquin CA, Guerrant RL, Lima AAM. Intestinal Permeability and Malabsorption of Rifampin and Isoniazid in Active Pulmonary Tuberculosis. Braz Jour Infec Dis. 2006 10 (6):374-379
448. Guerrant RL, Oria RB, Boissevain JR, Patrick PD, Lima AAM. Infectious Diseases, Balanced Polymorphisms and Human Evolution: A Declaration of Interdependence. Invited Commentary Current Infectious Disease Reports 2007, 9:83-85
449. Lima NL, Soares AM, Mota RMS, Monteiro HAS, Guerrant RL, Lima AAM. Wasting and Intestinal Barrier Function in Children Taking Alanyl-glutamine-Supplemented Enteral Formula. J Pediatr Gastroenterol Nutr. 2007 Mar;44(3):365-74
450. Parr JB, Sevilleja JE, Samie A, Alcantara C, Stroup SE, Kohli A, Lima AAM, Houpt ER, Guerrant RL. Detection and Quantification of Cryptosporidium in HCT-8 Cells and Human Fecal Specimens using Real-time PCR Am J Trop Med Hyg. 2007; 76(5): p. 938-942
451. Moore SR, Lorntz B, Lima AAM, Guerrant RL. Risk factors for adverse outcomes in developing countries. The Lancet. Vol 369 January 13, 2007 p.145-157
452. Alcantara CS, Guerrant RL. Update on Clostridium difficile infection. Current Gastroenterology Reports. Vol 2, Number 4, pp 310-314, 2007
453. Samie A, Obi CL, Tzipori S, Weiss LM, Guerrant RL. Microsporidiosis in South Africa: PCR detection in stool samples of HIV positive and HIV negative individuals and school children in the Vhembe district, Limpopo Province. Transactions of the Royal Society of Tropical Medicine and Hygiene (2007) 101, 547-554.
454. Samie A, Obi CL, Dillingham R, Pinkerton R, Guerrant RL. Enteroaggregative Escherichia coli in Venda, South Africa: Distribution of virulence-related genes by multiplex PCR in stool samples of HIV positive and HIV negative individuals and primary school children. Am. J. Trop. Med. Hyg., 77(1), 2007 142-150
455. Medeiros MS, Arruda EAG, Guerrant RL, Brown C, Hammarskjold ML, Rekosh D, Lima AAM. Genotype testing and antiretroviral resistance profiles from HIV-1 patients experiencing therapeutic failure in northeast Brazil. Braz J Inf Dis. 2007;11(4):390-394.
456. Medeiros MS, Arruda EA, Guerrant RL, Brown C, Hammarskjold ML, Rekosh D, Lima AA.Genotype testing and antiretroviral resistance profiles from HIV-1 patients experiencing therapeutic failure in northeast Brazil. Braz J Infect Dis. 2007 Aug;11(4):390-4. Erratum in: Braz J Infect Dis. 2007 Oct;11(5):528-9.
457. Maciel AFL, Oria RB, Braga-Neto MB, Braga AB, Carvalho EB, Lucena HBM, Brito GAC, Guerrant RL, Lima AAM. Role of Retinol in Protecting the Epithelial Cell Damage Induced by Clostridium difficile Toxin A. Toxicon 50 (2007) 1027-1040.
458. Alcantara Warren C, Guerrant RL. Cryptosporidium and Cryptosporidiosis, Second Edition. Editors Ronald Fayer and Lihua Xiao. Human Cryptosporidiosis: Clinical Disease and Pathology. Taylor & Francis Group, 2008 Chapter 8, pp 235-253.
459. Lorntz B, Boissevain JR, Dillingham RA, Kelly J, Ballard A, Scheld, WM, Guerrant RL. A Trans-university Center for Global Health. Academic Medicine. 2008 Vol. 83, No 2, February, 165-172.
460. Samie A, Obi CL, Bessong PO, Houpt E, Stroup S, Njayou M, Sabeta C, Mduluza T, Guerrant RL, Entamoeba histolytica: Genetic diversity of African strains based on the polymorphism of the serine-rich protein gene. Experimental Parasitology. Exp Parasitol. 2008 Mar;118(3):354-61.
461. Bushen OY, Guerrant RL. Etiology and Management of Diarrhea in HIV Infected Patients and Impact on Antiretroviral Therapy. Global HIV/AIDS Medicine Editors Volberding PA, Sande MA, Lange J, Greene WC, Gallant J. Section 5, Chapter 65, pp. 737-745, 2008
462. Braga MB, Alacantara C, Oria R, Monteiro M, Maciel AAS, Brito GAC, Lima AAM, Guerrant RL, Lima AAM. Alanyl-Glutamine and Glutamine Supplementation Improves 5-Fluorouracil-Induced Intestinal Epithelium Damage In Vitro. Dig Dis Sci. 2008 Oct;53(10):2687-96. Epub 2008 Mar 6.
463. Samie A, Obi CL, Franaziak J, Archbald-Pannone L, Bessong PO, Alcantara-Warren C, Guerrant RL. PCR Detection of Clostridium difficile triose phosphate isomerase (tpi), toxin A (tcdA), Toxin B (tcdB), Binary Toxin (cdtA, cdtB) and tcdC Genes in Vhembe District, South Africa. Am J Trop Med Hyg. 2008 Apr;78(4):577-585.
464. Petri WA, Miller M, Binder HJ, Levine M, Dillingham RA, and Guerrant RL. Enteric Infections, Diarrhea, and Their Impact on Function and Development. J Clin Invest. 2008 Apr 1;118(4):1277-1290.
465. Lima AAM, Nascimento NRF, Fang GD, Yotseff P, Toyama, MH, Guerrant RL, Fonteles MC. Role of Phospholipase A2 in Clostridium difficile Toxin A-Induced Disruption of Epithelial Integrity, Histologic Inflammatory Damage and Intestinal Secretion. J Appl Toxicol. 2008 Oct;28(7):849-57
466. Checkley W, Buckley G, Gilman RH, Assis AMO, Guerrant RL, Morris SS, Molbak K, Valentiner-Branth P, Lanata CF, Black RE, The Childhood Malnutrition and Diarrhea Network. Multi-country analysis of the effects of diarrhea on childhood stunting. Internat J Epi. 2008 Aug;37(4):816-30
467. Alcantara Warren C_, Destura RV, Sevilleja JEM, Barroso LF, Carvalho H, O'Brien A, Guerrant RL. Detection of epithelial injury and quantification of infection in the HCT8 organoid model of cryptosporidiosis. J Infect Dis 2008 Jul 1;198(1):143-9
468. Kotts A, Byung-Kwon C, Jimenez MEE, Warren CA, Gilbertson S, Guerrant RL, Murad F. Pyridopyrimidine derivates as inhibitors of cyclic nucleotide synthesis: application for treatment of diarrhea. Proc Natl Acad Sci U S A. 2008 Jun 17;105(24):8440-5.
469. Coutinho BP, Vieira CMG, Maciel JG, Thompson MR, Sevilleja JEAD, Lima AAM, Lopes MB, Oria RB, Guerrant RL. Cryptosporidium infection causes undernutrition, and conversely, weanling under-nutrition intensifies infection. J Parasitol. 2008 Jun 17:1.
470. Kohli A, Bushen OY, Pinkerton R, Houpt E, Stroup S, Newman R, Barrett L, Lima AAM, Guerrant RL. Giardia duodenalis assemblage, clinical presentation and markers of intestinal inflammation in Brazilian Children. Transactions of the Royal Society of Tropical Medicine and Hygiene (2008)102,718-725.
471. Houpt EL, Guerrant RL. Technology in global health: the need for "essential diagnostics". Lancet. 2008 Sep 13;372(9642):873-4.
472. Guerrant RL, Oriá RB, Moore SR, Oriá MOB, Lima AAM. Malnutrition as an enteric infectious disease with long-term effects on child development. Nutr Rev. 2008 Sep;66(9):487-505.
473. Lima AAM, Soares AM, Lima NL, Mota RMS, Maciel BLL, Blaner WS, Guerrant RL. Vitamin A supplementation effects on intestinal integrity, enteropathy and growth in Brazilian children: a double-blinded randomized clinical trial J Ped Gastro Nutr 2008 in press.
474. Cheng AC, Thielman NM, Guerrant RL, Chapter E. coli in Antimicrobial Therapy and Vaccines Editors: Victor Yu, Thomas Merigan, Steven Barriere, 2007.
475. Okhuysen PC, Lee SA, Guerrant RL. Genetic Susceptibility to Enteric Infections: Implications for Endemic and Travelers' Diarrhea. Textbook chapter. 2007
476. Lima AAM, Guerrant RL. "Cholera" in the Oxford Textbook of Medicine, 5th Edition 2007. Edited by Warrell DA, Cox TM, Firth JD, Benz Jr. EJ. 2007
477. Guerrant RL. Escherichia Enteric Infections chapter. Cecil Textbook of Medicine, 23nd Edition, Single Volume Set (Vols. 1 and 2) 2007
478. Vieira MM, Paik J, Blaner WS, Soares AM, Mota RMS, Guerrant RL, Lima AAM. Carotenoids, retinol and intestinal barrier function from children from northeast of Brazil.
479. Copeland C, Thompson M, Pinkerton R, Barrett L, Sevilleja JE, Lima A, Guerrant R. Fecal contamination of drinking water in a Brazilian shantytown: Importance of household storage and new human fecal marker testing.
480. Pawlowski, SW, Warren CA, Guerrant RL. When Infections Wins Out: Diagnosis and Treatment of Acute or Persistent Diarrhea. Gastroenterology 2009, 13th Edition. Intestinal Microbes in Health and Disease.
SUBMITTED FOR PUBLICATION
481. Guerrant RL, Fonteles MC, Thielman NM, Steiner TS, Ribeiro RA, Flores CA, Marcos FGR and Lima AAM. Microbial toxins as unique pharmacologic probes for cell signaling and secretion. Braz J Med Biol Res.
482. Oria RB, Patrick PD, Guerrant RL. Semantic fluency: A sensitive marker for cognitive impairment in children with heavy diarrhea burdens?
483. Assreuy AMS, Guerrant RL, Karginova OA, Carneiro-Filho BA, Brito GAC, Lima AAM, Timko MP. Biological Production of Alanyl-Glutamine Rich Proteins.
484. Oriá RB, Lopes MB, Hussaini I, Brito GAC, Castro-Costa CM, Lima AAM, Guerrant RL. Glutamine effect on intestinal maturation in growing mice.
485. Oria RB, Patrick PD, Blackman JA, Oria MOB, Pinkerton R, Vieira CMG, Thompson MR, Lima AAM, Guerrant RL. Balanced polymorphism again? The thrifty "Alzheimer's" APOE4 allele may have evolved because it protects children from diarrhea outcomes.
486. Samie A, Guerrant RL, Barrett L, Bessong PO, Igumbor EO, Obi CL. Intestinal Parasitic and Bacterial Pathogens in diarrheal and nondiarreal stools from the Vhembe district, Limpopo, South Africa, in the era of HIV and AIDS.
487. Guerrant RL, Hall R. Measuring and Addressing the Burden of Disease: Novel Therapeutics for Enteric Diseases.
488. Guerrant RL. Chapter 328: Escherichia coli and Other Enterobacteriaceae Infections. Cecil Textbook of Medicine 2006
489. Pinkerton R, Williams-Blangero S, Kohli A, Abreu C, Filho Q, Oria R, Lima AAM, Guerrant RL. Heritability as a major determinant of early childhood diarrhea.
490. Archbald-Pannone L, Alcantara C, Lyman J, Guerrant RL. Fluoroquinolone Use and Increased Incidence of C. difficile Associated Diarrhea.
491. Oria RB; Braga-Neto MB; Brito JRM, Warren CA, Sevejilla JE, Hussaini I, Lopes BM, Shi W, Vitek MP, Lima AAM, Guerrant RL. Apolipoprotein E effect on intestinal epithelial barrier following nutrient deprivation in vivo and in vitro.
492. Pinkerton R, Oria RB, Oria MOB, Patrick PD, Wiseman BL, Lima AAM, Moore SR, Niehaus MD, Guerrant RL. Early childhood diarrhea predicts cognitive delays in later childhood independently of malnutrition
493. Ladd FVL, Ladd AABL, Ribeiro AACM, Costa SBC, Coutinho BP, Feitosa GAS, de Castro-Costa CM, Castro IC, Oliveira BB, Guerrant RL, Lima AAM, Oria RB. The effect of zinc and gluatmine supplementation on brain development in suckling mice subjected to early post-natal malnutrition.
494. Kvalsund MP, Pomplona P, Oriá RB, Soares AM, Mota RMS, Lima NL, Fitzgerald RP, Patrick P, Guerrant RL, Lima AAM. Gender-Specific Improvements in Verbal Learning Following Zinc, Vitamin A, and Glutamine Supplementation in Brazilian Favela Children
495. Archbald-Pannone L, Alcantara-Warren C, Lyman J, Guerrant RL. Fluoroquinolone Use and Increased Incidence of C. difficile Associated Diarrhea
IN PREPARATION
496. Oriá RB, Kohli A, Bushen O, Lima AAM, Guerrant RL. Giardia infection impacts growth of Brazilian shantytown children.
497. Maciel JG, Coutinho BP. Effect of Cryptosporidial infection in malnourished neonatal mice
498. Pinkerton R, Abreu C, Sousa F, Soares A, Alencar S, DeBeers B, Copeland C, Lima A, Guerrant R Community Study of Household Drinking Water Quality and Child Health 2007.
499. Sevilleja JEAD, Copeland CC, Whitlock D, Boone JH, Lyerly DM, Guerrant RL. Detection of human fecal marker, Cryptosporidium, and Giardia using immunomagnetic separation in contaminated water samples
500. Sevilleja JEAD, Vieira CM, Coutinho BP, Pinkerton RC, Guerrant RL. Quantification of Cryptosporidial infection in stool of neonatal mice
501. Eyma E, Dillingham R, Samie A, Sevilleja JEAD, Guerrant RL. Improved diagnosis of cryptosporidial and microsporidial infections by PCR in patients with AIDS and diarrhea in Haiti
502. Coutinho BP. Heavy cryptosporidium infection and prolonged small intestine impairment following early post-natal malnutrition in mice.
503. Oria RB, Thompson MR, Oria MOB, Pinkerton R, Vieira CMG, Carvalho EB, Santos TJT, Lima AAM, Guerrant RL. Interleukin-1 Receptor Antagonist (IL1Ra) polymorphisms and diarrhea outcomes in Brazilian shantytown children.
504. Beers B, Copeland C, Pinkerton R, Barrett L, Sevilleja JE, Lima AAM, Guerrant RL. Water quality in a favela community in Brazil
505. Sevilleja JE, Vieira CM, Coutinho BP, Pinkerton RC, Guerrant RL. Crypto q PCR Mice (Quantification of Cryptosporisial Infection in Stool of Neonatal Mice)
506. Sevilleja JE, Copeland CC, Whitlock D, Boone JH, Lyerly D, Guerrant RL. Water (Detection of Human Fecal Contamination Using Immunomagnetic Separation in Water Samples)
507. Oria RB, Guerrant RL. Devastating Long-Term Effects on Child Development. Invited review, Nutrition Reviews.
508. Samie A, Barrett LJ, Bessong PO, Ramalivhana JN, Njayou M, Guerrant RL. Seroprevalence of Entamoeba histolytica in the context of HIV and AIDS: Case of the Limpopo Province, South Africa.
509. Maciel JG, Braga-Neto MB, Aguiar CV, Brito JRM, Carvalho UB, Guerrant RL, Lima AAM. Protective effect of Alanyl-Glutamine supplementation in Nelfinavir-Induced on the Intestinal Barrier Function: an in vitro and in vivo study.
510. Aguiar CV, Maciel JG, Braga-Neto MB, Monteiro MCSA, Monteiro SMN, Barbosa-Junior MS, Guerrant RL, Oria RB, Lima AAM. Effect of selected antiretroviral drugs on the intestinal epithelial barrier function in mice.
511. Pawlowski SW, Guerrant RL. Global Impact of Diarrheal Disease. Centers for Disease Control Health Information for International Travel, 2009.
MISCELLANEOUS LETTERS, EDITORIALS, BOOK REVIEWS, etc.
1. Guerrant RL. Vibrio cholerae and Cholera: Molecular to Global Perspectives. Ed. I. K. Wachsmuth, P.A. Blake and O. Olsvik. American Society of Microbiologists Press. Washington, D.C., 1994. American Journal of Tropical Medicine and Hygiene, 1995
2. Guerrant RL. Bench Aids for the Diagnosis of Intestinal Parasites. Series published by WHO, reviewed for Parasitology Today, 1995.
3. Guerrant RL. Presentation of Bailey K. Ashford Medal to Jonathan Ravdin, M.D., Ph.D. in Cincinnati on Nov. 15, 1994, Trop Med Hyg News 44(#3):29-30, 1995.
4. Guerrant RL and Theno DM. Escherichia coli 0157:H7. N Engl J Med 333(25):1711-1712, 1995. (CV #294).
5. Guerrant RL and Thielman NM. From Rwanda to Wisconsin: The global relevance of diarrheal diseases. Editorial. J Med. Microbiol 44:155-156, 1996.
6. Guerrant RL, Silva TMJ, Martins CAP. Answer letter . J Clin Med, in press 1996.(See CV #272)
7. Guerrant RL, Zaenker EI, Choi SW and Park CH. Authors' reply to letter. J Clin Micro 34:2337-2338, 1996. (See CV #301).
8. Houpt E, Ayeh-Kumi P, Barrett LJ, Guerrant RL. Guide to Diagnostic Parasitology. ASM 00:349-000, 1999.)
9. Dillingham R and Guerrant RL. Review of "Infections and Inequalities: The Modern Plagues" by Paul Farmer. JAMA, 286(19)2469-2470, 2001.
10. McCook A. Repeated bouts of diarrhea affect kids' IQ. Interview with R. Guerrant. Reuters, 2003
MEETING PRESENTATIONS & OTHER
1. Written up in Conde‚ Nast Traveler, Jan, 1994.
2. Guerrant RL. "Raspberries, hamburger and Milwaukee Water: The Tropics Come to Town. University of Virginia Associates Program Lecture Series. Richmond, Norfolk, Fairfax, Fall 1996.
3. Written up in Style Weekly, Oct. 22, 1996.
4. Featured in Globo/Sat/IDEA Television "Sciencia" "Tropical Diseases" 1997.
5. Guerrant RL. Health, Dignity and Population Control: The Danger of Malthusian Thinking" Summer on the Lawn (Global 2000: America's International Role in the 21st Century) 1997.
6. Guerrant RL. Congressional testimony before House Appropriations Committee for tropical medicine research April 15, 1997.
7. Guerrant RL. Congressional testimony before House Foreign Affairs Committee for tropical medicine research April 24, 1997.
8. Parlange M. Parasites in the Pipes (reference to crypto work, p. 361). BioScience 49(5):360-364,1999.
9. National ACP meeting, Food Poisoning.
10. April 27, 1999, NIH ICTDR meeting Long-term Impact & Intestinal Mal-Function from Persistent Diarrhea.
11. July 29, 1999, Military Medicine Courses USUHS Bethesda, Diarrheal Diseases.
12. September 17, 1999, NIH Micro Nutrients Meeting Role of Vitamin A in Intestinal Absorptive Function and meeting summary.
13. October 27, 1999, U Washington, Settle. Emerging Enteric Protozoa.
14. April 11, 2000, NIH-ICTDR presentation on Impact of Childhood Diarrhea
15. April 24, 2000, Meharry Medical symposium. "Careers in Global Health.
16. May 19, 2000, UCLA Grand rounds on Enteric Infections.
17. July 18, 2000, Military Medicine Course; USUHS, Bethesda; Approach to enteric infections."
18. September 9, 2000, IDSA, N. Orleans. "Traveler's Diarrhea."
19. September 30, 2000, Hefei China. Magnitude of diarrheal diseases.
20. October 2, 2000, Manila, Philippines Makati Symposium. Magnitude of diarrheal diseases."
21. October 18, 2001, Mexico City; magnitude and Impact of Infectious Diarrhea
22. October 31, 2000, ASTMH Nat'l meeting, Houston. "ORT: The most important advance and the greatest indictment of 20th Century Medicine." September 19, 2000, Oxford Krebs Symposium: "Role of glutamine in intestinal injury repair.".
23. February 25, 2001; IDSA/Stanford ID Course: "Discovering the Unacceptable Costs of the Diseases of Poverty: The most important medical advance or our new century."
24. March 2, 2001; IDSA/Stanford Course: "National Guidelines to Diagnosis and Management of Diarrheal Diseases."
25. March 10 2001, NIH TMRC Meeting in Bahia Brazil; "Increasing morbidity from diarrheal diseases, despite decreasing mortality."
26. April 30, 2001; IDSA Meeting on Novel Diagnostics (organized by DA Relman), Orlando. "Diagnosis of Diarrheal Diseases: Impact of New Methods.
27. May 7, 2001, NIH/ICTDR meetings, Bethesda; "New diagnostics amidst increasing morbidity."
28. June 7, 2001, Meridian International Center, US State Dept. National Intelligence Council, Washington, DC. "Global Health as a Compass for US Foreign Policy; The Unacceptable Costs of the Diseases of Poverty."
29. May 16-18, 2001. Pfizer Visiting Professor for 2001; Univ of Utah, SLC.
30. September 19, 2001, IOM paper at IOM workshop on Linking infectious agents and chronic conditions (electronic meeting since DC mtg cancelled wk after 9/11) "Potential Long-term consequences of early childhood enteric and parasitic infections."
31. October 19, 2001. "Magnitude and impact of diarrheal diseases," guest speaker at 450th Anniversary of UNAM, Mexico City.
32. April 8, 2002. "Diagnosis and Management of Infectious Diarrhea." Case Western Reserve University Infectious Diseases Course.
33. April 11, 12, 2002. Wesley Spink Lecturer and Grand Rounds speaker, University of Minnesota, Minneapolis, MN.
34. March - November, 2002; Multiple meetings at Institute of Medicine, National Academy of Sciences in Washington and Woods Hole on the Committee on Review of the Use of Scientific Criteria and Performance Standards for Safe Food, with Dr. Ricardo Molins.
35. September 19, 20, 2002. Dascomb Lecturer and Grand Rounds speaker, LSU, New Orleans, LA.
36. September 26, 27, 2002. Fall Convocation Speaker, University of Virginia at Wise.
37. October 21-22, 2002. Speaker on "Long-term Developmental Impact of Early Childhood Diarrheal Diseases" at Institute of Medicine Conference on "Linking Infectious Agents and Chronic Conditions," Washington, DC.
38. October 26, 2002. "Rapid Diagnostics in Diarrheal Diseases," IDSA Symposium, Chicago IL.
39. November 21, 22, 2002. Medical Grand Rounds and Research Conference as Visiting Professor, University of Iowa, Iowa City.
40. December 19, 2002. "Early Childhood Diarrhea at 0-2 years old is Associated with Impaired Executive Cognitive Functioning (Verbal Fluency) at 6-12 years old." US-Japan Cholera and Related Diarrheal Diseases Conference, Okinawa, Japan.
41. Plus numerous local lectures at meetings of Committee on Foreign Affairs, Cholera History, Global Ethics, Retired Faculty Club, International Residential College, et al.
42. Pinkerton, Relana; Anita Kohli, Reinaldo Oria, Alberto Soares, Oluma Bushen, Aldo A.M Lima, Richard L. Guerrant. Early infection with Giardia lamblia predicts further growth faltering in Brazilianshantytown children. University of Virginia, Charlottesville, VA, United States ASTMH November 2004.
43. Amoah-Dankwa J.,Raul V.Destura and Oluma Y.Bushen,Leah J.Barrett,Richard L.Guerrant. Effects of zinc on migration of injured IEC-6 cells. ICTDR Meeting, Bethesda MD, May 2004.
44. Destura,R.V.; Brito GAC; Amoah-Dankwa,J.; Bushen,O.Y.; Guerrant RL. Effect of Arginine and Glutamine on Intestinal Epithelial Cell Injury Repair. ICTDR Meeting, Bethesda MD, May 2004.
45. Dillingham R, Leite R, Lima AAM, Bushen OY, Ziermann R, Kashuba A, Guerrant RL. Diarrhea, Malabsorption and Antiretroviral (ARV) Resistance in Patients Infected with Human Immunodeficiency Virus (HIV) in Northeastern Brazil, IDSA Boston October 2004.
46. Bushen,OY Kohli A, Pinkerton RC, Lima AAM, Houpt E, Destura,RV, Guerrant RL. Symptomatic Children Shed More Cryptosporidial Oocysts than Asymptomatic Children IDSA Boston October 2004.
47. Oriá RB, Lopes MB, Hussaini I, Shi W, Brito GAC, Vieira CMG, Pamplona P, Lima AAM, Guerrant RL APOE4 knock-out Mice Have Impaired Intestinal Adaptation Responses to Re-Feeding After Being Challenged by Undernutrition. ASTMH Miami November 2004 Late Breaker.
48. Guerrant RL, Oria R, Patrick P, Lima AAM. The "Alzheimer's gene" APOE4 May have Evolved Because it Protects the Cognitive Development of Children Experiencing Heavy Burdens of Diarrhea US-Japan Cooperative Medical Science Program-Kyoto, Japan December, 2004.