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Untitled Document
A FEW RECENT PUBLICATIONS
2001.
Du, Q., Stukenberg,
T. and Macara, I.G. (2001) A mammalian Partner of Inscuteable (Pins) binds NuMA
and regulates mitotic spindle assembly and organization. Nature
Cell Biol. 3: 1069-1075.
2002.
Smith, A.E., Slepchenko, B., Schaff, J., Loew, L. and Macara, I.G. (2002) Systems
analysis of Ran transport into the nucleus. Science
295: 488-491.
Lindsay, M., Plafker, K., Smith, A.E., Clurman, B.E. and Macara, I.G. (2002).
Npap60 is a tri-stable switch that stimulates importin-a/b-mediated nuclear
import. Cell 110: 349-360.
2003.
Hurd,
T.W.*, Gao, L.*, Roh, M.H., Macara, I.G. and Margolis, B. (2003) Direct
interaction of two polarity complexes implicated in epithelial tight junctiona
assembly. Nature Cell Biol. 5: 137-142. (*authors
contributed equally).
Garrard, S., M., Capaldo, C.T., Gao, L., Rosen, M.K., Macara, I.G. and Tomchick,
D. (2003) Structure of Cdc42 in a complex with the GTPase-binding domain
of the cell polarity protein, Par6. EMBO J 22: 1125-1133.
Yi, R., Qin, Y.,
Macara, I.G. and Cullen, B.R. (2003) Exportin-5 mediates the nuclear export
of pre-microRNAs and short hairpin RNAs. Genes & Dev.
17: 3011-3016.
Macara,
I.G. (2003) Parsing the polarity code. Nature Mol. Cell Biol.
Reviews 5: 220-231.
2004.
Plafker,
S.M., Plafker, K.S., Weissman, A.M. and Macara, I.G. (2004) J.
Cell Biol. (in press)
Du,
Q. and Macara, I.G. (2004) Mammalian Pins functions as a conformational
switch to couple NuMA and G-proteins. Cell 1119: 1-20.
2005.
Chen,
X. and Macara, I.G.. (2005) Par-3 regulates tight junction assembly through
the Rac exchange factor, Tiam1. Nature Cell Biol. 7:
262 - 269.
Riddick, G. and Macara,
I.G. (2005) A systems analysis of importin-?/? mediated nuclear protein
import. J. Cell Biol. 168: 1027-1038 (cover
picture; commentary in J Cell Biol).
Qin, Y., Capaldo, C.,
Gumbiner, B. and Macara, I.G. (2005) The mammalian Scribble polarity protein
regulates epithelial cell adhesion and migration through E-cadherin. J.
Cell Biol. 171: 1061-71.
2006.
Zhang,
H. and Macara, I.G. (2006) The polarity protein PAR-3 and TIAM1 co-operate
in dendritic spine morphogenesis. Nature Cell Biol.
8: 227- 237. (Commentary in Cell)
Chen, X. and Macara,
I.G. (2006) PAR-3 regulates cofilin phosphorylation through LIMK2. J.
Cell Biol. 172: 671-678
Macara,
I.G. and Spang, A.(2006) Closing the GAP between polarity and vesicle transport.
Cell 125: 419-421
2007
Kremer,
B.E., Adang, L.A. and Macara, I.G. (2007) Septins regulate actin organization
and cell-cycle arrest through nuclear accumulation of NCK mediated by SOCS7.
Cell 130: 837-850. (Reviewed in Cell).
Goldstein, B. and Macara, I.G. (2007)
The PAR proteins: fundamental players in cell polarity. Dev. Cell
13: 609-622.
Sirajuddin M, Farkasovsky M, Hauer
F, Kühlmann D, Macara IG, Weyand M, Stark H, Wittinghofer A.(2007)
Structural insight into filament formation
by mammalian septins. Nature (article) 449: 311-315.
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