Molecular Genetics Program Members

Joyce L. Hamlin, Ph.D., Program Leader

Professor & Chair, Department of Biochemistry & Molecular Genetics

Chromosome replication, gene amplification, S-phase damage-sensing checkpoints

Paul Adler, Ph.D.

Professor, Department of Biology

Genetics of cell polarity and relationship to tissue structure and uncontrolled growth

David Auble, Ph.D.

Associate Professor, Department of Biochemistry & Molecular Genetics

Chromatin remodeling and DNA repair in cancer

Ann L. Beyer, Ph.D.

Professor, Department of Microbiology

Ribosome biogenesis and its up-regulation in cancer; action of camptothecin on rRNA synthesis

Daniel J. Burke, Ph.D.

Professor, Department of Biochemistry and Molecular Genetics

The mitotic spindle checkpoint and its deregulation in cancer

Patrick J. Concannon, Ph.D.

Professor, Department of Biochemistry and Molecular Genetics

Cellular DNA damage responses; Breast cancer genetics; Genetics of type 1 diabetes

Anindya Dutta, Ph.D.

Harry Flood Byrd Professor, Department of Biochemistry & Molecular Genetics

G1-S transition in cancer cells and mis-regulation in cancer; regulation of chromosomal replication.

Dan Engel, Ph.D.

Associate Professor, Department of Microbiology

Function of the adenovirus E1A oncoprotein

Patrick Grant, Ph.D.

Associate Professor, Department of Biochemistry & Molecular Genetics

Covalent histone modifications and deregulation in cancer

Marie-Louise Hammarskjold, M.D., Ph.D.

Professor, Department of Microbiology

Post-translational regulation of RNA expression and derangement in cancer

Gary Kupfer, M.D.

Associate Professor, Department of Microbiology

Molecular basis of cancer in Fanconi anemia

James Larner, M.D.

Associate Professor, Department of Radiation Oncology

Radiation activation of ATM; S-phase damage-sensing checkpoints

Mani Mahadevan, M.D.

Associate Professor, Department of Pathology

Trinucleotide repeats and genetic instability

Marty Mayo, Ph.D.

Associate Professor of Biochemistry & Molecular Genetics

Role of the transcription factor NF-κB in the inhibition of apoptosis

Bryce Paschal, Ph.D.

Associate Professor, Department of Biochemistry & Molecular Genetics

Nuclear import of androgen receptor as a target for chemotherapy in prostate cancer

William R. Pearson, Ph.D.

Professor, Department of Biochemistry & Molecular Genetics

Computational algorithms for analyzing genome and protein sequence data

Lucy Pemberton, Ph.D.

Associate Professor, Department of Microbiology

Chromatin assembly and genetic instability

Heidi Scrable, Ph.D.

Associate Professor, Department of Neuroscience

Role of p53 in aging and cancer 

Jeffrey S. Smith, Ph.D.

Associate Professor, Department of Biochemistry & Molecular Genetics

Chromatin modifications, silencing, aging, and apoptosis

M. Mitchell Smith, Ph.D.

Professor, Department of Microbiology

DNA damage, chromosome instability, altered gene expression, and cancer

P. Todd Stukenberg, Ph.D.

Associate Professor, Department of Biochemistry & Molecular Genetics

Chromosome segregation, aneuploidy, and tumorogenesis

David Wotton, Ph.D.

Associate Professor, Department of Biochemistry & Molecular Genetics

Cell cycle regulation and dis-regulation by TGF-b

Member list current as of February 2008