Endocrinology Program Members |
Margaret A. Shupnik, Ph.D., Program LeaderProfessor, Department of Medicine & PhysiologyEstrogen receptor (ER) action in gene transcription and cell proliferation; estrogen receptor subtype-specific actions and cross-talk with intracellular signaling pathways Theresa A. Guise, M.D., Program Co-leaderProfessor, Department of Internal MedicineMolecular mechanisms in bone metastases of breast and prostate cancer, translational models to test efficacy of pharmaceutical interventions George P. Amorino, Ph.D.Assistant Professor of Research, Radiation OncologyRadiosensitization in prostate cancer models; modulation of signal transduction pathways in cellular radiosensitivity; neuroendocrine cells in prostate cancer John M. Chirgwin, Ph.D.Professor, Department of Internal MedicineRegulation of gene expression in skeletal metastasis of breast and prostate cancer, autocrine motility factor/phosphoglucose isomerase as a causal factor in cancer cachexia, and potential role of prostate PSA in skeletal metastasis Gregory Clines, M.D., Ph.D.Assistant Professor of Internal MedicineMetastatic bone disease metastasis Richard N. Day, Ph.D.Associate Professor, Department of Internal MedicineCellular assembly of transcription factor and nuclear receptor-coregulatory protein complexes and regulation of gene transcription Dan Gioeli, Ph.D.Assistant Professor of Research, Department of MicrobiologyPeptide growth factor and androgen signaling cross-talk and contribution to progression of prostate cancer from androgen-dependent to androgen-independent disease Phillip Gordon, M.D., Ph.D.Assistant Professor, Department of PediatricsRole of insulin-like growth factor-II binding protein-2 (IGFBP-2) in colorectal cancer biology Carla Green, Ph.D.Associate Professor, Department of BiologyCircadian control of neuroendocrine genes Joel M. Linden, Ph.D.Professor, Department of Internal MedicineHypothalamic, pituitary and peripheral interactions in the pathogenesis of pituitary adenomas invasion and recurrence; molecular genetics characteristics of gliomas and tumor behavior John C. Marshall, M.D., Ph.D.Professor, Department of Internal MedicineMechanisms of GnRH regulation of gonadotropin and steroid synthesis; role of follistatin and activin in modulating SMAD activity and cellular function Jerry L. Nadler, M.D.Professor and Division Chief, Division of Endocrinology, Department of Internal MedicineMechanisms of cytokine action and inflammation; products of arachidonic and linoleic acid metabolism of the 12-Lipoxygeanse (12-LO) enzymes leading to cellular growth, matrix production, apoptosis and cell migration Prabhakara P. Reddi, Ph.D.Assistant Professor of PathologyTestis-specific transcription factors and gene expression, Sperm-specific antigens in prostate cancer Emilie F. Rissman, Ph.D.Professor, Department of Biochemistry and Molecular GeneticsRole of steroids, steroid receptors subtypes, and neuropeptides in behavior; behavioral effects of androgen ablation Richard J. Santen, M.D.Professor, Department of Internal MedicineEstrogen regulated control of proliferation and differentiation of hormone dependent breast cancer; nongenomic and genotoxic effects of estrogen Corinne M. Silva, Ph.D.Assistant Professor, Department of Medicine & MicrobiologyRole of STAT proteins in c-Src and EGF receptor signaling pathways, proliferation, and tumorigenesis; role of STATs in crosstalk with steroid signaling Michael O. Thorner, D.Sc., FACP, FRCP, M.B.Professor of MedicineEndocrinology and metabolism, specifically neuroendocrinology and hypothalamic pituitary disease Rosalie M. Uht, M.D., Ph.D.Assistant Professor, Department of PathologyMechanisms of estrogen receptor isoform transcription through the Activator Protein-1 alternate pathway; mechanisms by which histone deacetylases regulate estrogen receptor activity Wei Yue, M.D., Ph.D.Associate Professor of Research, Department of Internal MedicineMechanisms of estrogen and aromatase action breast cancer initiation and progression, and development of therapeutic strategies for hormone-dependent breast cancer |
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Member list current as of February 2008 |