Structural Biology Program Members

John H. Bushweller, Ph.D., Program Director

Professor, Dept. of Molecular Physiology and Biological Physics, Dept. of Chemistry

Structural biology of leukemia related proteins; targeted drug design for leukemia (Leukemia)

Marwan K. Al-Shawi, Ph.D.

Associate Professor of Research, Dept. of Molecular Physiology and Biological Physics

Mechanism of P-glycoprotein (Drug resistance)

Jay C. Brown, Ph.D.

Professor, Dept. of Microbiology

Herpes viruses and cancer etiology and treatment (Chemotherapy side effects, Lymphoma)

David S. Cafiso, Ph.D.

Professor, Dept. of Chemistry

Protein recruitment to membrane and cell signaling (Ras signaling and cancer)

Tomasz Cierpicki, Ph.D.

Assistant Professor, Molecular Physiology and Biological Physics

Derewenda Lab 

Zygmunt S. Derewenda, Ph.D.

Professor, Dept. of Molecular Physiology and Biological Physics

Structural biology of cell migration proteins and the Rho signaling pathway (Metastasis)

Urszula Derwenda, Ph.D.

Assistant Professor of Research, Dept. of Molecular Physiology and Biological Physics

Structural biology of cell migration proteins and the Rho signaling pathway (Metastasis)

Edward H. Egelman, Ph.D.

Professor, Dept. of Biochemistry and Molecular Genetics

Recombination and DNA repair (Genomic instability and cancer)

Jolanta Grembecka, Ph.D.

Assistant Professor, Molecular Physiology and Biological Physics

Instructor of research

Sepideh Khorasanizadeh, Ph.D.

Associate Professor, Dept. of Biochemistry and Molecular Genetics

Structural biology of epigenetic signaling (HDAC and Methylation inhibitors)

Wladek Minor, Ph.D.

Professor, Dept. of Molecular Physiology and Biological Physics

Methodology for x-ray crystallography (Leukemia)

Robert Nakamoto, Ph.D.

Professor, Dept. of Molecular Physiology and Biological Physics

P-glycoprotein; Structural biology of membrane proteins (Drug resistance)

Fraydoon Rastinejad, Ph.D.

Associate Professor, Dept. of Pharmacology

Structural biology of nuclear receptor transcription factors (Prostate, Breast cancer)

Zhifeng Shao, Ph.D.

Professor, Dept. of Molecular Physiology and Biological Physics

DNA replication (Genomic instability and cancer)

Avril V. Somlyo, Ph.D.

Professor, Dept. of Molecular Physiology and Biological Physics

Rho signaling pathway (Prostate cancer, Gliomas, Angiogenesis)

Lukas Tamm, Ph.D.

Professor, Dept. of Molecular Physiology and Biological Physics

Membrane fusion and membrane protein folding (Ras signaling)

Michael Wiener, Ph.D.

Associate Professor, Dept. of Molecular Physiology and Biological Physics

Structural biology of membrane proteins (Cisplatin uptake)

Member list current as of February 2008