Structural Biology Program Members

John H. Bushweller, Ph.D., Program Director

Professor, Molecular Physiology and Biological Physics

Structural biology of leukemia related proteins; targeted drug design for leukemia (Leukemia)

Marwan K. Al-Shawi, Ph.D.

Associate Professor of Research of Molecular Physiology and Biological Physics

Mechanism of P-glycoprotein (Drug resistance)

Jay C. Brown, Ph.D.

Professor of Microbiology

Herpes viruses and cancer etiology and treatment (Chemotherapy side effects, Lymphoma)

David S. Cafiso, Ph.D.

Professor of Chemistry

Protein recruitment to membrane and cell signaling (Ras signaling and cancer)

Tomasz Cierpicki, Ph.D.

Assistant Professor, Molecular Physiology and Biological Physics

Derewenda Lab 

Linda Columbus, Ph.D.

Assistant Professor of Chemistry

Biophysical Chemistry: Membrane protein structure, function, and dynamics

Zygmunt S. Derewenda, Ph.D.

Professor of Molecular Physiology and Biological Physics

Structural biology of cell migration proteins and the Rho signaling pathway (Metastasis)

Urszula Derwenda, Ph.D.

Assistant Professor of Research of Molecular Physiology and Biological Physics

Structural biology of cell migration proteins and the Rho signaling pathway (Metastasis)

Edward H. Egelman, Ph.D.

Professor of Biochemistry and Molecular Genetics

Recombination and DNA repair (Genomic instability and cancer)

Jolanta Grembecka, Ph.D.

Assistant Professor, Molecular Physiology and Biological Physics

Instructor of research

Sepideh Khorasanizadeh, Ph.D.

Associate Professor of Biochemistry and Molecular Genetics

Structural biology of epigenetic signaling (HDAC and Methylation inhibitors)

Wladek Minor, Ph.D.

Professor of Molecular Physiology and Biological Physics

Methodology for x-ray crystallography (Leukemia)

Robert Nakamoto, Ph.D.

Professor of Molecular Physiology and Biological Physics

P-glycoprotein; Structural biology of membrane proteins (Drug resistance)

Fraydoon Rastinejad, Ph.D.

Professor of Pharmacology

Structural biology of nuclear receptor transcription factors (Prostate, Breast cancer)

Zhifeng Shao, Ph.D.

Professor of Molecular Physiology and Biological Physics

DNA replication (Genomic instability and cancer)

Avril V. Somlyo, Ph.D.

Professor of Molecular Physiology and Biological Physics

Rho signaling pathway (Prostate cancer, Gliomas, Angiogenesis)

Lukas K. Tamm, Ph.D.

Professor of Molecular Physiology and Biological Physics

Membrane fusion and membrane protein folding (Ras signaling)

Michael C. Wiener, Ph.D.

Associate Professor of Molecular Physiology and Biological Physics

Structural biology of membrane proteins (Cisplatin uptake)

Member list current as of October 2008