The Current State of Mass Spectrometry at the University of Virginia.
This symposium on December 12th, 2006, featured presentations on current and forthcoming techniques in mass spectrometry at the University of Virginia available to all investigators. The symposium was sponsored by Applied Biosystems.
General Mass Spectrometry in the Cores.
Dr. David Smalley, Mellon Biomarkers Core.
Background on available instruments.
Biomarker Discovery
Dr. David Smalley, Mellon Biomarkers Core.
Current projects to find biomarkers using mass spectrometry
Posttranslational Modifications and new additions to instrumentation
Dr. Nicholas Sherman, Mass Spectrometry Core
Descriptions of post-translational modifications and how current and future instrumenation has improved their identification. Methods for comparing different tissue samples.
Automated Comparative Quantification in Complex Mixtures
Dr. Dennis Templeton, Department of Pathology, Collaborative Mass Spectrometry Facility
A technique for quantifying differences between tissue samples and an invitation to collaborate on projects comparing tissues
Dr. Brian Williamson, Applied Biosystems
Description of the ITRAQ technique for comparative proteomics and application to a model system. A brief description of the method is from an Applied Biosystems newsletter.
Mapping Phosphorylation within the Adhesion Proteome
Dr. Thomas Parsons, Department of Microbiology and Cell Migration Consortium
Results from the application of mass spectrometry to identify phosphorylation sites in adhesion proteins. Results from this work are available at the Cell Migration Gateway