University of Virginia Health System

Anatomy, Pharmacology, and Physiology of Local Anesthetics and Neuraxial Anesthesia

Goals

• Review the anatomy relevant to the use of local anesthetics in neuraxial anesthesia
• Review the pharmacology and physiology of local anesthetics
• Discuss current indications and techniques of neuraxial anesthesia

Introduction

Regional anesthesia necessitates a thorough understanding of the anatomy of the peripheral and central nervous systems.  An understanding of the bony landmarks related to the peripheral nerves and spinal cord allows one to perform peripheral nerve blocks as well as neuraxial anesthesia in the safest manner possible.  We will start with the bony anatomy of the vertebral column followed by the spinal cord and peripheral nerves, and finally the pain pathways.  The following presentation requires Adobe Reader.  Free download available.