International Healthcare Worker Safety Center

Bibliography

April 2008

 

1.         Aisaka K, Itabashi K, Nagasaka K., Kuroda K, Arita S, Takane V. Influence of Novel Blunt Needles (Ethiguard) on Safety for Gynecologic Operations. Obstetrics & Gynecology 2008; 109(4 (supplement)):25S.
ABSTRACT: OBJECTIVE: The present study was performed to evaluate the safety of the Ethiguard (a new type of blunt needle) by measurement of the resistance to puncture using a surgical rubber glove and chicken breast meat.
METHODS: The resistance of a surgical glove and chicken breast meat (5 mm and 10 mm thick) to being punctured by three needles, a conventional round needle (J-765D), Ethiguard CTXB (circle taper extra large blunt), and a usual type of blunt needle (BP-1) was measured by the computer control system autograph (AGS-100B; Shimadzu Company, Tokyo, Japan). This procedure was repeated 10 times on each material.
RESULTS: The values measured for the resistance of the surgical glove to being pierced by the three needles were 27.110.1, 17515.4, and 352.421.7 g, respectively (P.001). In contrast, the resistance of the 5-mm and 10-mm chicken breast meat test pieces to being pierced by the blunt needle was found to be significantly greater than their resistance to being pierced by the other two needles (5 mm: 13.82.7, 18.64.2, 45.95.5 g, P.001; 10 mm: 32.44.2, 37.85.8, 77.96.8 g, P.001). These results demonstrated that the Ethiguard was less likely than the conventional round needle to puncture a surgical glove, but it had the same capacity as the conventional round needle to penetrate tissue.
CONCLUSION: The use of the Ethiguard is effective in preventing needle-stick accidents but still penetrates tissues satisfactorily, and also it is effective in protecting against such infections as human immunodeficiency virus (HIV) and hepatitis C virus (HCV).

2.         Alamgir H, Cvitkovich Y, Astrakianakis G, Yu S, Yassi A. Needlestick and other potential blood and body fluid exposures among health care workers in British Columbia, Canada. Am J Infect Control 2008; 36(1):12-21.
ABSTRACT: BACKGROUND: Health care workers have high risk of exposure to human blood and body fluids (BBF) from patients in acute care and residents in nursing homes or personal homes. METHODS: This analysis examined the epidemiology for BBF exposure across health care settings (acute care, nursing homes, and community care). Detailed analysis of BBF exposure among the health care workforce in 3 British Columbian health regions was conducted by Poisson regression modeling, with generalized estimating equations to determine the relative risk associated with various occupations. RESULTS: Acute care had the majority of needlestick, sharps, and splash events with the BBF exposure rate in acute care 2 to 3 times higher compared with nursing home and community care settings. Registered nurses had the highest frequency of needlestick, sharps, and splash events. Laboratory assistants had the highest exposure rates from needlestick injuries and splashes, whereas licensed practical nurses had the highest exposure rate from sharps. Most needlestick injuries (51.3%) occurred at the patient's bedside. Sharps incidents occurred primarily in operating rooms (26.9%) and at the patient's bedside (20.9%). Splashes occurred most frequently at the patient's bedside (46.1%) and predominantly affected the eyes or face/mouth. The majority of needlestick/sharps injuries occurred during use for registered nurses, during disposal for licensed practical nurses, and after disposal for care aides. CONCLUSION: The high risk of BBF exposure for some occupations indicates there is room for improvement to reduce BBF exposure by targeting high-risk groups for prevention strategies

3.         Apisarnthanarak A, Babcock HM, Fraser VJ. The effect of nondevice interventions to reduce needlestick injuries among health care workers in a Thai tertiary care center. Am J Infect Control 2008; 36(1):74-75.
ABSTRACT: To the Editor: It is estimated that more than 380,000 needlestick injuries (NSIs) are reported by hospital staff members each year in the United States.1 In developing countries, health care workers (HCWs) face even greater risks because of the higher prevalence of bloodborne pathogens and the use of certain medical equipments, such as nonretracting finger-stick lancets and glass capillary tubes to test for common tropical diseases.[2] and [3] Although safety-engineered devices have been incorporated to help reduce NSIs in the United States, the role of such devices in developing countries remains controversial.

4.         Boal WL, Leiss JK, Sousa S, Lyden JT, Li J, Jagger J. The National study to prevent blood exposure in paramedics: Exposure reporting. Am J Ind Med 2008; 51(3):213-222.
ABSTRACT: BACKGROUND: This survey was conducted to provide national incidence rates and risk factors for exposure to blood among paramedics. The present analysis assesses reporting of exposures to employers. METHODS: A questionnaire was mailed in 2002-2003 to a national sample of paramedics selected using a two-stage design. Information on exposure reporting was obtained on the two most recent exposures for each of five routes of exposure. RESULTS: Forty-nine percent of all exposures to blood and 72% of needlesticks were reported to employers. The main reason for under-reporting was not considering the exposure a "significant risk." Females reported significantly more total exposures than males. Reporting of needlesticks was significantly less common among respondents who believed most needlesticks were due to circumstances under the worker's control. Reporting was non-significantly more common among workers who believed reporting exposures helps management prevent future exposures. Reporting may have been positively associated with workplace safety culture. CONCLUSIONS: This survey indicates there is need to improve the reporting of blood exposures by paramedics to their employers, and more work is needed to understand the reasons for under-reporting. Gender, safety culture, perception of risk, and other personal attitudes may all affect reporting behavior. Am. J. Ind. Med. 51:213-222, 2008. (c) 2008 Wiley-Liss, Inc

5.         Byass P, D'Ambruoso L. Cellular telephone networks in developing countries. The Lancet 2008; 371(9613):650-642.
ABSTRACT: While undertaking community-based follow-ups of maternal deaths in Burkina Faso and Indonesia, we were struck by the irony of sitting in some of the world's poorest households, wherein many mothers had died after failing to access health services, and yet where good cellular telephone signals were available (figure). From such households it is possible to call anywhere in the world-but there is generally no designated emergency number nor means of getting medical advice or assistance via a portable telephone

6.         Chopra M, Munro S, Lavis JN, Vist G, Bennett S. Effects of policy options for human resources for health: an analysis of systematic reviews. The Lancet 2008; 371(9613):668-674.
ABSTRACT: Background: Policy makers face challenges to ensure an appropriate supply and distribution of trained health workers and to manage their performance in delivery of services, especially in countries with low and middle incomes. We aimed to identify all available policy options to address human resources for health in such countries, and to assess the effectiveness of these policy options.

Methods: We searched Medline and Embase from 1979 to September, 2006, the Cochrane Library, and the Human Resources for Health Global Resource Center database. We also searched up to 10 years of archives from five relevant journals, and consulted experts. We included systematic reviews in English which assessed the effects of policy options that could affect the training, distribution, regulation, financing, management, organisation, or performance of health workers. Two reviewers independently assessed each review for eligibility and quality, and systematically extracted data about main effects. We also assessed whether the policy options were equitable in their effects; suitable for scaling up; and applicable to countries with low and middle incomes.

Findings: 28 of the 759 systematic reviews of effects that we identified were eligible according to our criteria. Of these, only a few included studies from countries with low and middle incomes, and some reviews were of low quality. Most evidence focused on organisational mechanisms for human resources, such as substitution or shifting tasks between different types of health workers, or extension of their roles; performance-enhancing strategies such as quality improvement or continuing education strategies; promotion of teamwork; and changes to workflow. Of all policy options, the use of lay health workers had the greatest proportion of reviews in countries with a range of incomes, from high to low.

Interpretation: We have identified a need for more systematic reviews on the effects of policy options to improve human resources for health in countries with low and middle incomes, for assessments of any interventions that policy makers introduce to plan and manage human resources for health, and for other research to aid policy makers in these countries

7.         Crisp N, Gawanas B, Sharp I. Training the health workforce: scaling up, saving lives. The Lancet 2008; 371(9613):689-691.
ABSTRACT: Over a billion people worldwide have little or no access to health services and the help and advice of health workers. There is good evidence that health workers affect health outcomes. The density of health workers is significant in accounting for rates of maternal mortality, infant mortality, under-5 mortality, and immunisation rates across countries.  Similarly, assessments of disease-oriented country programmes have found that the lack of health workers is one of the major bottlenecks in implementing evidence-based interventions to improve maternal and child health, and to address HIV/AIDS, malaria, and tuberculosis. There is also evidence for the effectiveness of specific cadres of health workers, including community and mid-level workers.  But, as the 2006 World Health Report, Working Together for Health,highlighted, there is a global shortage of some 4·3 million health workers, with the greatest shortages in the poorest countries.

The causes of the crisis are many, from a global rise in chronic disease and an ageing population, to poor local working conditions and international migration.6 But the massive shortfall in production of trained health workers underpins all other problems. To take one example, Ethiopia trains about 200 doctors a year for a population of about 75 million; the UK trains more than 6000 for a population of about 60 million.

8.         Doull L, Campbell F. Human resources for health in fragile states. The Lancet 2008; 371(9613):626-627.
ABSTRACT: Human resources are crucial for a functioning health system. The global shortage of health workers is evident in many developing countries, especially in.  fragile states-countries whose governments, for various reasons, cannot or will not deliver core functions to most of the population.  Building and retaining a skilled and motivated health workforce is particularly challenging in settings where staff might be under extreme pressure (eg, during conflicts, long-term underinvestment in the health sector, and the HIV/AIDS epidemic). Furthermore, for health professionals, there are growing opportunities that encourage movement from fragile states to search for better professional and economic environments. The results are shortages of health staff and an inability to provide even basic health care.

9.         Gershon RR, Pogorzelska M, Qureshi KA, Sherman M. Home health care registered nurses and the risk of percutaneous injuries: a pilot study. Am J Infect Control 2008; 36(3):165-172.
ABSTRACT: BACKGROUND: Home health care is the fastest-growing sector in the health care industry, expected to grow 66% over the next 10 years. Yet data on occupational health hazards, including the potential risk of exposure to blood and body fluids, associated with the home care setting remain very limited. As part of a larger study of bloodborne pathogen risk in non-hospital-based registered nurses (RNs), data from 72 home health care nurses were separately analyzed to identify risk of blood/body fluid exposure. METHODS: A 152-item self-administered mailed risk assessment questionnaire was completed by RNs employed in home health care agencies in New York State. RESULTS: Nine (13%) of the home health care nurses experienced 10 needlesticks in the 12-month period before the study. Only 4 of the needlesticks were formally reported to the nurse's employer. The devices most frequently associated with needlesticks were hollow-bore and phlebotomy needles, and included 3 needles with safety features. Exposure was most commonly attributed to patient actions, followed by disposal-related activities. CONCLUSIONS: These data suggest that home health care nurses may be at potential occupational risk for bloodborne pathogen exposure. Risk management strategies tailored to the home health care setting may be most effective in reducing this risk

10.       Glassman A, Becker L, Makinen M, de Ferranti D. Planning and costing human resources for health. The Lancet 2008; 371(9613):693-695.
ABSTRACT: Human resources are crucial for the provision of health care and represent the largest single use of public spending on health in developing countries.  Yet countries face an ongoing challenge when it comes to financing human resources for health (HRH) sufficiently to sustain an adequate supply of health workers and stimulate greater productivity and more effective health care.

Several papers prepared for the 2006 World Health Report and the Global Health Workforce Alliance describe the HRH financing gap and the variables such as economic growth, government revenues, aid, fiscal sustainability targets, and priority-setting practices that affect the ability of governments and donors to increase spending on this input.

Inspired by the global HRH movement, some countries, mostly in Africa, have undertaken strategic planning exercises to estimate their HRH needs.  But these plans rarely include a reliable analysis of the financing needs or structures required to achieve the desired levels of care. When they do address costs, they typically use provider-population ratios to estimate the number of additional staff needed in each cadre, then multiply those numbers by current public-sector salaries and allowances (or some assumed salary increment). Shortfalls are determined by comparing this figure with current and projected health-sector budgets. Resource mobilisation options via aid and public-sector priority-setting are then discussed.

11.       Hagopian A, Micek MA, Vio F, Gimbel-Sherr K, Montoyo P. What if we decided to take care of everyone who needed treatment? Workforce planning in Mozambique using simulation of demand for HIV/AIDS care. Hum Resour Health 2008; 6(1):3.
ABSTRACT: ABSTRACT: BACKGROUND: The growing AIDS epidemic in southern Africa is placing an increased strain on health systems, which are experiencing rising steadily patient loads. Health care systems are tackling the barriers to serving large populations in scaled-up operations. One of the most significant challenges in this effort is securing the health care workforce to deliver care in settings where the manpower is already in short supply. METHODS: We have produced a demand-driven staffing model using simple spreadsheet technology, based on treatment protocols for HIV-positive patients that adhere to Mozambican guidelines. The model can be adjusted for the volumes of patients at differing stages of their disease, varying provider productivity, proportion who are pregnant, attrition rates, and other variables. RESULTS: Our model projects the need for health workers using three different kinds of goals: 1) the number of patients to be placed on anti-retroviral therapy (ART), 2) the number of HIV-positive patients to be enrolled for treatment, and 3) the number of patients to be enrolled in a treatment facility per month. CONCLUSIONS: We propose three scenarios, depending on numbers of patients enrolled. In the first scenario, we start with 8000 patients on ART and increase that number to 58 000 at the end of three years (those were the goals for the country of Mozambique). This would require thirteen clinicians and just over ten nurses by the end of the first year, and 67 clinicians and 47 nurses at the end of the third year. In a second scenario, we start with 34 000 patients enrolled for care (not all of them on ART), and increase to 94 000 by the end of the third year, requiring a growth in clinician staff from 18 to 28. In a third scenario, we start a new clinic and enrol 200 new patients per month for three years, requiring 1.2 clinicians in year 1 and 2.2 by the end of year 3. Other clinician types in the model include nurses, social workers, pharmacists, phlebotomists, and peer counsellors. This planning tool could lead to more realistic and appropriate estimates of workforce levels required to provide high-quality HIV care in a low-resource settings

12.       Lefebvre DR, Strande LF, Hewitt CW. An enzyme-mediated assay to quantify inoculation volume delivered by suture needlestick injury: two gloves are better than one. J Am Coll Surg 2008; 206(1):113-122.
ABSTRACT: BACKGROUND: Acquiring a blood-borne disease is a risk of performing operations. Most data about seroconversion are based on hollow-bore needlesticks. Some studies have examined the inoculation volumes of pure blood delivered by suture needles. There is a lack of data about the effect of double-gloving on contaminant transmission in less viscous fluids that are not prone to coagulation. STUDY DESIGN: We used enzymatic colorimetry to quantify the volume of inoculation delivered by a suture needle that was coated with an aqueous contaminant. Substrate color change was measured using a microplate reader. Both cutting and tapered suture needles were tested against five different glove types and differing numbers of glove layers (from zero to three). RESULTS: One glove layer removed 97% of contaminant from tapered needles and 65% from cutting needles, compared with the no-glove control data. Additional glove layers did not significantly improve contaminant removal from tapered needles (p > 0.05). For the cutting needle, 2 glove layers removed 91% of contaminant, which was significantly better than a single glove (p = 0.002). Three glove layers did not afford statistically significant additional protection (p = 0.122). There were no statistically significant differences between glove types (p = 0.41). CONCLUSIONS: With an aqueous needle contaminant, a single glove layer removes contaminant from tapered needles as effectively as multiple glove layers. For cutting needles, double-glove layering offers superior protection. There is no advantage to triple-glove layering. A surgeon should double-glove for maximum safety. Additionally, a surgeon should take advantage of other risk-reduction strategies, such as sharps safety, risk management, and use of sharpless instrumentation when possible

13.       Mbongwe B, Mmereki BT, Magashula A. Healthcare waste management: current practices in selected healthcare facilities, Botswana. Waste Manag 2008; 28(1):226-233.
ABSTRACT: Healthcare waste management continues to present an array of challenges for developing countries, and Botswana is no exception. The possible impact of healthcare waste on public health and the environment has received a lot of attention such that Waste Management dedicated a special issue to the management of healthcare waste (Healthcare Wastes Management, 2005. Waste Management 25(6) 567-665). As the demand for more healthcare facilities increases, there is also an increase on waste generation from these facilities. This situation requires an organised system of healthcare waste management to curb public health risks as well as occupational hazards among healthcare workers as a result of poor waste management. This paper reviews current waste management practices at the healthcare facility level and proposes possible options for improvement in Botswana

14.       McCoy D, Bennett S, Witter S et al. Salaries and incomes of health workers in sub-Saharan Africa. The Lancet 2008; 371(9613):675-681.
ABSTRACT: Summary: Public-sector health workers are vital to the functioning of health systems. We aimed to investigate pay structures for health workers in the public sector in sub-Saharan Africa; the adequacy of incomes for health workers; the management of public-sector pay; and the fiscal and macroeconomic factors that impinge on pay policy for the public sector. Because salary differentials affect staff migration and retention, we also discuss pay in the private sector. We surveyed historical trends in the pay of civil servants in Africa over the past 40 years. We used some empirical data, but found that accurate and complete data were scarce. The available data suggested that pay structures vary across countries, and are often structured in complex ways. Health workers also commonly use other sources of income to supplement their formal pay. The pay and income of health workers varies widely, whether between countries, by comparison with cost of living, or between the public and private sectors. To optimise the distribution and mix of health workers, policy interventions to address their pay and incomes are needed. Fiscal constraints to increased salaries might need to be overcome in many countries, and non-financial incentives improved

15.       Merli R. CDC Probes Needlesticks, Possible HIV Infection Among Laundry Workers. American Laundry News 2008; 3/21/08.
ABSTRACT: The Centers for Disease Control and Prevention (CDC) is investigating as many as four more potential cases of laundry and housekeeping workers infected with HIV, the virus that causes AIDS, as a result of needlestick injuries they suffered at work.

16.       Mills EJ, Schabas WA, Volmink J et al. Should active recruitment of health workers from sub-Saharan Africa be viewed as a crime? The Lancet 2008; 371(9613):685-688.
ABSTRACT: Shortages of health-care staff are endemic in sub-Saharan Africa.  Overall, there is one physician for every 8000 people in the region. In the worst affected countries, such as Malawi, the physician-to-population ratio is just 0·02 for every 1000 (one per 50 000). There are also huge disparities between rural and urban areas: rural parts of South Africa have 14 times fewer doctors than the national average.  These numbers are very different to those in developed countries: the UK, for example, has over 100 times more physicians per population than Malawi.  Furthermore, almost one in ten doctors working in the UK are from Africa. The insufficiency of health staff to provide even basic services is one of the most pressing impediments to health-care delivery in resource-poor settings. The consequences are clearly shown by the inverse relation that exists between health-care worker density and mortality

17.       Mornar SJ, Perlow JH. Blunt suture needle use in laceration and episiotomy repair at vaginal delivery. Am J Obstet Gynecol 2008.
ABSTRACT: OBJECTIVE: By surveying obstetricians regarding the use of blunt suture needles for laceration and episiotomy repair, the purpose of this study was to determine whether blunt suture needles represent a safe and effective alternative to sharp needles. STUDY DESIGN: Blunt suture needles were made available at our institution for repairs at vaginal delivery. Participating physicians indicated their personal history of needlestick injuries and rated the blunt suture needle after completing the repair. Categorical variables were analyzed using Fisher's exact test and a 2-tailed P < .05 was considered significant. RESULTS: Attending and resident physicians completed 80 surveys, and 83% reported previous needlestick injuries. Blunt suture needles were rated as excellent or good by 92.5% (95% confidence interval 84.6 to 96.5%). No needlestick injuries occurred. CONCLUSION: In an effort to reduce needlestick injuries, the use of blunt suture needles is safe and effective for repairs at vaginal delivery

18.       Musharrafieh UM, Bizri AR, Nassar NT et al. Health care workers' exposure to blood-borne pathogens in Lebanon. Occup Med (Lond) 2008; 58(2):94-98.
ABSTRACT: BACKGROUND: Accidental exposure to blood-borne pathogens (BBPs) is a risk for health care workers (HCWs). AIM: To study the pattern of occupational exposure to blood and body fluids (BBFs) at a tertiary care hospital. METHODS: This study reports a 17-year experience (1985-2001) of ongoing surveillance of HCW exposure to BBFs at a 420-bed academic tertiary care hospital. RESULTS: A total of 1590 BBF exposure-related accidents were reported to the Infection Control Office. The trend showed a decrease in these exposures over the years with an average +/- standard error of 96 +/- 8.6 incidents per year. In the last 6 years, the average rate of BBF exposures was 0.57 per 100 admissions per year (average of needlestick injuries alone was 0.46 per 100 admissions). For 2001, the rates of exposure were found to be 13% for house officers, 9% for medical student, 8% for attending physicians, 5% for nurses, 4% for housekeeping, 4% for technicians and 2% for auxiliary services employees. The reason for the incident, when stated, was attributed to a procedural intervention (29%), improper disposal of sharps (18%), to recapping (11%) and to other causes (5%). CONCLUSIONS: The current study in Lebanon showed that exposure of HCWs to BBPs remains a problem. This can be projected to other hospitals in the country and raises the need to implement infection control standards more efficiently. Similar studies should be done prospectively on a yearly basis to study rates and identify high-risk groups

19.       Nsubuga P, White M, Fontaine R, Simone P. Training programmes for field epidemiology. The Lancet 2008; 371(9613):630-631.
ABSTRACT: Public-health systems are an important subset of the health systems that are needed to meet the Millennium Development Goals (MDGs). How many public-health workers will be needed to achieve the MDGs is unknown, but there is an urgent unmet need.  Moreover, even as the MDGs are being implemented, the newly revised International Health Regulations call for the establishment of a group of experts in public-health surveillance and response in all countries.

One strategy that has worked in the building of public-health surveillance and response systems and the workforce to operate the systems is the implementation of training programmes in field epidemiology.3 Over the past 27 years, 29 countries have created these programmes in partnership with the US Centers for Disease Control and Prevention (CDC) and WHO to directly build and strengthen public-health systems, while simultaneously training future public-health leaders. The programmes are based on CDC's Epidemic Intelligence Service which is a 2-year public-health leadership-training programme. More than 1000 public-health leaders have graduated from the training programmes in field epidemiology, and many more have completed short courses. Many graduates of training programmes in field epidemiology have moved into leadership positions within the ministries of health of their own countries

20.       Omaswa F. Human resources for global health: time for action is now. The Lancet 2008; 371(9613):625-626.
ABSTRACT: Over several decades, a global health-workforce crisis has developed before our eyes. The crisis is characterised by widespread global shortages, maldistribution of personnel within and between countries, migration of local health workers, and poor working conditions.

The factors that led to this crisis include increased demand for care in developed countries with ageing populations, an upsurge of new and old pandemics in low-income countries with poorly performing economies, and neglect. Counterproductive and poorly administered solutions, such as bans and across-the-board ceilings on recruitment, have aggravated these factors.

21.       Ozgediz D, Galukande M, Mabweijano J et al. The Neglect of the Global Surgical Workforce: Experience and Evidence from Uganda. World J Surg 2008.
ABSTRACT: BACKGROUND: Africa's health workforce crisis has recently been emphasized by major international organizations. As a part of this discussion, it has become apparent that the workforce required to deliver surgical services has been significantly neglected. METHODS: This paper reviews some of the reasons for this relative neglect and emphasizes its importance to health systems and public health. We report the first comprehensive analysis of the surgical workforce in Uganda, identify challenges to workforce development, and evaluate current programs addressing these challenges. This was performed through a literature review, analysis of existing policies to improve surgical access, and pilot retrospective studies of surgical output and workforce in nine rural hospitals. RESULTS: Uganda has a shortage of surgical personnel in comparison to higher income countries, but the precise gap is unknown. The most significant challenges to workforce development include recruitment, training, retention, and infrastructure for service delivery. Curricular innovations, international collaborations, and development of research capacity are some of the initiatives underway to overcome these challenges. Several programs and policies are addressing the maldistribution of the surgical workforce in urban areas. These programs include surgical camps, specialist outreach, and decentralization of surgical services. Each has the advantage of improving access to care, but sustainability has been an issue for all of these programs. Initial results from nine hospitals show that surgical output is similar to previous studies and lags far behind estimates in higher-income countries. Task-shifting to non-physician surgical personnel is one possible future alternative. CONCLUSIONS: The experience of Uganda is representative of other low-income countries and may provide valuable lessons. Greater attention must be paid to this critical aspect of the global crisis in human resources for health

22.       Ozgediz D, Kijjambu S, Galukande M et al. Africa's neglected surgical workforce crisis. The Lancet 2008; 371(9613):627-628.
ABSTRACT: Funding priorities in Africa typically favour infectious diseases, and surgery and perioperative care have been neglected, even though essential surgical care at district hospitals is more cost effective than some other highly prioritised interventions, such as antiretroviral therapy for HIV.   Recent focus on the workforce needed for male circumcision to prevent HIV transmission is an exception.  Injuries create the greatest surgical burden, followed by cancers, congenital anomalies, and complications of childbirth.

Few surgical procedures are done in Africa compared with the numbers in high-income countries, but precise information on the exact unmet need is lacking.  Although workforce limitations contribute to this shortfall, detailed estimates of surgical and anaesthesia staff for the continent and individual countries are unavailable or outdated.

23.       Peng B, Tully PJ, Boss K, Hiller JE. Sharps Injury and Body Fluid Exposure Among Health Care Workers in an Australian Tertiary Hospital. Asia Pac J Public Health 2008; 20(2):139-147.
ABSTRACT: To examine sharps injury and body fluid exposure among health care workers, a descriptive epidemiological study was conducted in a 1000-bed tertiary hospital between 2000 and 2003 using surveillance data of all reported sharps injuries and body fluid exposures. A total of 640 sharps injuries and body fluid exposures were reported from hospital and nonhospital staff, although no seroconversions to HIV, hepatitis B virus, or hepatitis C virus were observed during the study period. Nurses reported 47% of sharps injuries and 68% of body fluid exposures, medical staff reported 38% and 16%, and other nonmedical staff notified 5% and 4%, respectively, while nonhospital staff reported the rest. Hollow-bore needles accounted for 56% of sharps injuries, while 11% of the incidents were sustained during recapping and inappropriate disposal. Further research into Australian work practices, disposal systems, education strategies, and the use of safety sharps should be emphasized to implement strategies to reduce work-related injuries among health care workers

24.       Pick W. Lack of evidence hampers human-resources policy making. The Lancet 2008; 371(9613):629-630.
ABSTRACT: In today's Lancet, Mickey Chopra and colleagues describe the dearth of evidence for policy making on human resources for health. Despite their study being a systematic review of systematic reviews over a set period, albeit of reports in English, they make a compelling case for more research to inform policy makers. At a time when there is a resurgence of interest in this field, Chopra and colleagues' overview serves as a timely reminder to researchers that much more information is needed if we are to persuade those responsible for health services, and especially human resources for health, to take decisions that will contribute to the solution of the global crisis in the staffing of health systems

25.       Pillay Y, Mahlati P. Health-worker salaries and incomes in sub-Saharan Africa. The Lancet 2008; 371(9613):632-634.
ABSTRACT: There is global focus on the need to strengthen health systems to achieve the Millennium Development Goals by 2015, especially in sub-Saharan Africa. Health workers are a key ingredient of health systems. In today's Lancet, David McCoy and colleagues1 contribute to the understanding of public-sector health workers' salaries. In sub-Saharan Africa in particular the recruitment and retention of public-sector workers are vitally important for health.

According to the Global Health Workforce Alliance in 2006, sub-Saharan Africa faces the most chronic shortage of health workers.2 The Alliance noted that this region has 11% of the world's population and a quarter of the global burden of disease, but has only 3% of the world's health workforce and spends less than 1% of the global health expenditure. According to Physicians for Human Rights, more than 80% of sub-Saharan countries do not meet WHO's minimum recommendations for the numbers of doctors and nurses.3 And about 65 000 physicians and 70 000 nurses born in Africa were working in developed countries in 2000

26.       Poz MRD. Understanding women's contribution to the health workforce. The Lancet 2008; 371(9613):641-642.
ABSTRACT: One of my first activities after my appointment as Director of Human Resources for Health for the State of Rio de Janeiro, Brazil, in 1987, was to assess and appraise the health workforce at that time. To me, if the government had a better understanding of its human resources in the health system, it could better plan and adopt adequate options to improve the health of the population, while ameliorating the working conditions of its more than 20 000 employees.

Globally, it is estimated that health workers account for some 2·5-10·0% of the total labour force in a country (Hum Resour Health 2003; 1 : 5). In Rio de Janeiro, about a third of the health workforce is found in the public sector. The results from our assessment of the state's health workforce showed that women were predominantly running the delivery of health-care services in Rio de Janeiro. And by that I do not just mean nursing aides or cleaning crews; nor did our figures include the immense burden of informal domestic care provided by women in the home. No, our analysis revealed that most health-care providers and administrative workers within the health-care system were women

27.       Robinson M, Clark P. Forging solutions to health worker migration. The Lancet 2008; 371(9613):691-693.
ABSTRACT: All over the world, increased demand from wealthier countries resulting from ageing populations and medical advances has pulled large numbers of health workers from some of the world's poorest countries-many of whom are left with acute shortages of health workers of their own. Africa carries 25% of the world's disease burden yet has only 3% of the world's health workers and 1% of the world's economic resources to meet that challenge. Migration, together with other factors in many source countries such as insufficient health systems, low wages, and poor working conditions, are key factors determining low health-worker density in countries with the lowest health indicators, In Zambia, for example, there are fewer than 0·12 physicians for every 1000 people, whereas Italy enjoys 4·2 physicians for every 1000 people.1 Between 1993 and 2002, Ghana lost 604 trained doctors; roughly half of all doctors and a third of nurses leave the country after training.2 Globally, WHO estimates that 4·3 million more health workers are required to achieve the health-related Millennium Development Goals and has identified 57 countries with critical shortages of health workers-36 of these countries are in Africa

28.       Schatz JJ. Zambia's health-worker crisis. The Lancet 2008; 371(9613):638-639.
ABSTRACT: Zambia has a dire shortage of health workers, with less than a third the doctor-patient ratio recommended by WHO. But the crisis is gaining new attention and the southern African nation has become a testing ground for several initiatives. Joseph J Schatz reports from Lusaka.

Just past the entrance to the sprawling University Teaching Hospital (UTH) in Lusaka, a yellow sign serves as a stark reminder of the massive health-worker shortage facing this southern African nation. "Kindly take note that members of the staff at UTH work under very strenuous and demanding conditions due to the increase in the disease burden and critical shortages of manpower", reads the sign, put up after a series of confrontations between angry patients and over-stretched nurses and doctors. "It may take a bit of time…Assaulting any member of staff is a criminal offence

29.       Schatz JJ. Francis Omaswa: tackling the shortage of health workers. The Lancet 2008; 371(9613):643-642.
ABSTRACT: Francis Omaswa was working as head of cardiothoracic surgery at Kenyatta National Hospital in Nairobi, in 1982, leading an open-heart surgery team, when he decided to take a slight detour. At the invitation of the Association of Surgeons of East Africa, Omaswa travelled back to Uganda, his homeland, and set out for a remote mission hospital in the town of Ngora. He spent the next 5 years on an experimental project testing out the most cost-effective ways to deliver quality health services in a rural African setting. In so doing, he figured out how to make health systems work. And, according to Omaswa, one crucial thing about making health systems work is that they need health workers: "Money cannot take drugs from the airport into the mouths of humans. You need people. It sounds obvious but the world doesn't work like that."

More than two decades later, Omaswa looks back on his time in Ngora as a pivotal training ground for his current role as Executive Director of WHO's Global Health Workforce Alliance (GHWA). The group, which holds a major conference in Kampala next month, is charged with coordinating the global response to the massive shortage of doctors, nurses, and health workers that is paralysing the health systems of many countries throughout the developing world. "It's the basis on which I understand health systems and health care in low-income countries", Omaswa says

30.       Taegtmeyer M, Suckling RM, Nguku PM et al. Working with risk: Occupational safety issues among healthcare workers in Kenya. AIDS Care 2008; 20(3):304-310.
ABSTRACT: The objective of this study was to explore knowledge of, attitudes towards and practice of post-exposure prophylaxis (PEP) among healthcare workers (HCWs) in the Thika district, Kenya. We used site and population-based surveys, qualitative interviews and operational research with 650 staff at risk of needlestick injuries (NSIs). Research was conducted over a 5-year period in five phases: (1) a bio-safety assessment; (2) a staff survey: serum drawn for anonymous HIV testing; (3) interventions: biosafety measures, antiretrovirals for PEP and hepatitis B vaccine; (4) a repeat survey to assess uptake and acceptability of interventions; in-depth group and individual interviews were conducted; and (5) health system monitoring outside a research setting. The main outcome measures were bio-safety standards in clinical areas, knowledge, attitudes and practice as regards to PEP, HIV-sero-prevalence in healthcare workers, uptake of interventions, reasons for poor uptake elucidated and sustainability indicators. Results showed that HCWs had the same HIV sero-prevalence as the general population but were at risk from poor bio-safety. The incidence of NSIs was 0.97 per healthcare worker per year. Twenty-one percent had had an HIV test in the last year. After one year there was a significant drop in the number of NSIs (OR: 0.4; CI: 0.3-0.6; p<0.001) and a significant increase in the number of HCWs accessing HIV testing (OR: 1.55; CI: 1.2-2.1; p=0.003). In comparison to uptake of hepatitis B vaccination (88% of those requiring vaccine) the uptake of PEP was low (4% of those who had NSIs). In-depth interviews revealed this was due to HCWs fear of HIV testing and their perception of NSIs as low risk. We concluded that Bio-safety remains the most significant intervention through reducing the number of NSIs. Post-exposure prophylaxis can be made readily available in a Kenyan district. However, where HIV testing remains stigmatised uptake will be limited - particularly in the initial phases of a programme

31.       The L. Finding solutions to the human resources for health crisis. The Lancet 2008; 371(9613):623.
ABSTRACT: Earlier this month, medical workers at Lira Hospital in northern Uganda went on strike to demand unpaid allowances promised by the government for working in this war-torn area. Seven patients died. There were reports of bodies decomposing in wards and women in the maternity ward assisting with each other's deliveries. This shocking situation serves as a stark reminder of the reality of the human resources for health crisis in sub-Saharan Africa. It also highlights the complexities of the crisis, where competing human rights, health-care needs, and international agendas clash, and in which the poor and most vulnerable suffer the most.

32.       Wada K, Sakata Y, Fujino Y et al. The Association of Needlestick Injury with Depressive Symptoms among First-year Medical Residents in Japan. Ind Health 2008; 45(6):750-755.
ABSTRACT: Depressive symptoms among medical residents are common. The objective of this study was to determine the association of depressive symptoms with needlestick injury among first-year medical residents (so-called "intern"). We conducted a prospective cohort study among 107 medical residents in 14 training hospitals. The baseline survey was conducted in August 2005 and the follow-up survey was conducted in March 2006. Depressive symptoms were based on the Center for Epidemiological Study of Depression. Factors associated with depressive symptoms were examined using logistic regression analysis. For medical residents without depressive symptoms at the baseline survey, needlestick injury events were associated with depressive symptoms at the follow-up survey (corrected odds ratio [cOR]=2.98; 95% confidence interval [CI], 1.16-3.70). Because it was not possible to determine when the medical residents developed depressive symptoms, it is not possible to definitely determine causality between needlestick injury and depressive symptoms, although these findings are suggestive. Therefore, it would seem prudent to suggest the provision of mental health services to medical residents sustaining a needlestick injury since this may be helpful in identifying and treating depression

33.       Whitby M, McLaws ML, Slater K. Needlestick injuries in a major teaching hospital: the worthwhile effect of hospital-wide replacement of conventional hollow-bore needles. Am J Infect Control 2008; 36(3):180-186.
ABSTRACT: BACKGROUND: Needlestick injury (NSI) with hollow-bore needles remains a significant risk of bloodborne virus acquisition in health care workers. The impact on NSI rates after substantial replacement of conventional hollow-bore needles with the simultaneous introduction of safety-engineered devices (SEDs) including retractable syringes, needle-free intravenous (IV) systems, and safety winged butterfly needles was examined in an 800-bed Australian university hospital. METHODS: NSIs were prospectively monitored for 2 years (2005-2006) after the introduction of SEDs and compared with prospectively collected preintervention NSI data (2000-2004). RESULTS: Preintervention hollow-bore NSI rates over 10 years persisted at a constant rate between 3.01 and 3.77 per 100 full-time equivalent employees (FTE) (P = .31). Rates for 2005 (1.93; 95% CI: 1.48-2.47 per 100 FTE) and 2006 (1.50; 95% CI: 1.11-1.97 per 100 FTE) were significantly lower than the average rate for the preintervention years (3.39; 95% CI: 2.7-4.24 per 100 FTE, P = .00004). This represents a fall of 49% (43.1%-55.7%) in hollow-bore NSI, contributed to by the virtual elimination of NSI related to accessing IV lines. More importantly, high-risk injuries were also reduced 57% by retractable syringe use with an overall budgetary increase of approximately US $90,000 per annum. CONCLUSION: Introduction of SEDs results in an impressive fall in NSI with minimal cost outlay

34.       White SM. Needlestick injuries - a testing time. Nurs Crit Care 2008; 13(1):1-2.

35.       White SM. Needlestick injuries - a testing time. Nurs Crit Care 2008; 13(1):1-2.
ABSTRACT: Critical care staff need to be aware of recent changes in the law. Using the example of human immunodeficiency virus (HIV) and hepatitis screening after needlestick injuries involving unconscious patients, this editorial will examine the implications of the Human Tissue Act 2004 (HTA) and the Mental Capacity Act 2005 (MCA) for critical care practice and explore potential solutions to the problem.

In response to high-profile public concerns over unethical organ retention at Alder Hey Hospital and the Bristol Royal Infirmary, the government introduced the Human Tissue Bill that was enacted as the HTA in 2004 and enforced from 1 September 2006.

36.       Wicker S, Jung J, Allwinn R, Gottschalk R, Rabenau HF. Prevalence and prevention of needlestick injuries among health care workers in a German university hospital. Int Arch Occup Environ Health 2008; 81(3):347-354.
ABSTRACT: OBJECTIVE: Health care workers (HCWs) are exposed to bloodborne pathogens, especially hepatitis B (HBV), hepatitis C (HCV), and human immunodeficiency virus (HIV) through job-related risk factors like needlestick, stab, scratch, cut, or other bloody injuries. Needlestick injuries can be prevented by safer devices. METHODS: The purpose of this study was to investigate the frequency and causes of needlestick injuries in a German university hospital. Data were obtained by an anonymous, self-reporting questionnaire. We calculated the share of reported needlestick injuries, which could have been prevented by using safety devices. RESULTS: 31.4% (n = 226) of participant HCWs had sustained at least one needlestick injury in the last 12 months. A wide variation in the number of reported needlestick injuries was evident across disciplines, ranging from 46.9% (n = 91/194) among medical staff in surgery and 18.7% (n = 53/283) among HCWs in pediatrics. Of all occupational groups, physicians have the highest risk to experience needlestick injuries (55.1%-n = 129/234). Evaluating the kind of activity under which the needlestick injury occurred, on average 34% (n = 191/561) of all needlestick injuries could have been avoided by the use of safety devices. Taking all medical disciplines and procedures into consideration, safety devices are available for 35.1% (n = 197/561) of needlestick injuries sustained. However, there was a significant difference across various medical disciplines in the share of needlestick injuries which might have been avoidable: Pediatrics (83.7%), gynecology (83.7%), anesthesia (59.3%), dermatology (33.3%), and surgery (11.9%). In our study, only 13.2% (n = 74/561) of needlestick injuries could have been prevented by organizational measures. CONCLUSION: There is a high rate of needlestick injuries in the daily routine of a hospital. The rate of such injuries depends on the medical discipline. Implementation of safety devices will lead to an improvement in medical staff's health and safety

37.       Hospital's liability affirmed over nurse's needlestick injury. AIDS Policy & Law 2007; 22(12).
ABSTRACT: An appeals court affirmed a ruling that a nurse contracted HIV from a needlestick injury that occurred four years before she tested positive for the virus.

On June 30, 1994, Anglea Price was working as a certified nursing assistant for Christus Health/St. Joseph Hospital.  While drawing blood from a patient with HIV who had developed AIDS, Price accidently stuck her finger with a needle that she used on the patient.  Price immediately reported the needlestick to her supervisors and went to the hospital's emergency room.  She tested negative for HIV on the date of the incident.

38.       Study: Gaps persist in HBV immunizations. Hospital Employee Health 2007; 26(2):21-22.
ABSTRACT: About one in four health care workers who are offered the hepatitis B vaccine decline to take it, according to a study by the Centers for Disease Control and Prevention.  Although the occupational risk of acquiring hepatitis B has declined dramatically since the 1980s, health care workers still need to be vigilant about vaccinations, says Ian Williams, PhD, MS, chief of the Epidemiologic Research and Field Investigations Team in the Division of Viral Hepatitis at the CDC.

39.       Rapid response lowers HIV needlestick risk: Rural hospitals may not have PEP on stock. Hospital Employee Health 2007; 26(1):6-8.
ABSTRACT: AIDS has forever altered the way health care workers fiew the threat of infectious disease.  Although HCWs had long been at risk of contracting tuberculosis, hepatitis B, and other serious diseases, the AIDS epidemic in the 1980s brought a new level of fear -- and a focous on the need for workplace protections.

40.       Statement on sharps safety. Bull Am Coll Surg 2007; 92(10):34-37.
ABSTRACT: Sharps injuries and surgical glove tears continue to expose surgeons and operating room (OR) personnel to the risk of human immunodeficiency virus, viral hepatitis B, viral hepatitis C, and bacterial infections from patients. Patients' blood makes contact with the skin or mucous membranes of OR personnel in as many as 50 percent of operations, with cuts or needlesticks occurring in as many as 15 percent of operations. Surgeons and first assistants are at highest risk for injury, sustaining up to 59 percent of the injuries in the operating room. Scrub personnel have the second highest frequency of injuries in the OR (19%), followed by anesthesiologists (6%) and circulating nurses (6%). For surgeons, suture needles are the most frequent source of sharps injuries.

41.       Nonhospital health-care workers at substantial risk of exposure to bloodbornepathogens.  12-20-2007. Columbia University's Mailman School of Public Health.
ABSTRACT: In one of the largest studies of its kind, researchers from the Columbia University Mailman School of Public Health assessed the risk of exposure to bloodborne pathogens among non-hospital based registered nurses (RNs), and found that nearly one out of 10 of the more than 1100 nurse participants reported at least one needlestick injury in the previous 12 months.

42.       Computer-based training not up to OSHA bloodborne pathogen standard: Program must allow for real-time Q&A. Hospital Employee Health 2007; 26(3):25-27.
ABSTRACT: Technology has opened new avenues for health and safety training, but it comes with a caveat: Computer-based modules may not meet the requirements of the bloodborne pathogen standard.
     The U.S. Occupational Safety and Health Administration (OSHA) requires employers provide "direct access to a qualified trainer during training," which can include e-mail only if the trainer is available to respond to the e-mail immediately.

43.       Al-Dwairi ZN. Infection Control Procedures in Commercial Dental Laboratories in Jordan. J Dent Educ 2007; 71(9):1223-1227.
ABSTRACT: The risk of cross-infection in dental clinics and laboratories has attracted the attention of practitioners for the past few years, yet several medical centers have discarded compliance with infection control guidelines, resulting in a non-safe environment for research and medical care. In Jordan, there is lack of known standard infection control programs that are conducted by the Jordanian Dental Technology Association and routinely practiced in commercial dental laboratories. The aim of this study was to examine the knowledge and practices in infection control among dental technicians working in commercial dental laboratories in Jordan. Data were collected from the dental technicians by a mailed questionnaire developed by the author. The questionnaire asked respondents to provide demographic data about age and gender and to answer questions about their knowledge and practice of infection control measures: use of gloves, use of protective eyeglasses and face shields, hepatitis B virus (HBV) vaccination, laboratory work disinfection when sent to or received from dental offices. and regularly changing pot water or pumice slurry. Of the total respondents, 135 were males (67.5 percent) and sixty-five were females (32.5 percent) with a mean age of twenty-seven years. The results showed that 24 percent of laboratory technicians wore gloves when receiving dental impressions, while 16 percent continued to wear them while working. Eyeglasses and protective face shields were regularly worn by 35 percent (70/200) and 40 percent (80/200) of technicians, respectively. Fourteen (14 percent) had received an HBV vaccination, and 17 percent inquired if any disinfection measures were taken in the clinic. Eighty-six percent of the technicians reported that pumice slurry and curing bath water were rarely changed. Only five dental technicians (two males and three females) were considered to be fully compliant with the inventory of infection control measures, a compliance rate of 2.5 percent with no significant difference between males and females (p>0.05). In conclusion, there is lack of compliance with infection control procedures of dental technicians working in commercial laboratories in Jordan

44.       Allegranzi B, Pittet D. Healthcare-associated infection in developing countries: simple solutions to meet complex challenges. Infection Control & Hospital Epidemiology 2007; 28(12):1323-1327.

45.       Allos BM, Schaffner W. Transmission of hepatitis B in the health care setting: the elephant in the room ... or the mouse? J Infect Dis 2007; 195(9):1245-1247.
ABSTRACT: Most infections with hepatitis B virus in the United States occur as a result of specific high-risk behaviors. Most, but not all. Approximately 1.2 million people living in the United States have chronic hepatitis B virus infection [1]. Each year, another 8000 acute infections-mostly in adults-are reported to the Centers for Disease Control and Prevention (CDC) [1]. Many of these infections are the result of sexual activity (both heterosexual and homosexual) or intravenous drug use; however, up to one-third report no risk factors for infection [2]. Although it is likely that a large number of these risk-deniers simply are unwilling to acknowledge behaviors they may view as socially stigmatizing, it also is possible that some have acquired their hepatitis B infection in nonclassical ways. The blunt epidemiologic tools used in recent decades to assess risks of transmission have been important and useful. Nevertheless, finer implements may be needed to tease out smaller but perhaps substantial risk factors.

46.       American Nurses Association. Medication errors and syringe safety are top concerns for nurses according to new national study. New Jersey Nurse 2007; 37(4):4-5.
ABSTRACT: SILVER SPRING, MD - June 19, 2007 --The American Nurses Association (ANA) today announced the findings of the 2007 Study of Injectable Medication Errors, an independent nationwide survey of 1,039 nurses.  According to the research, the overwhelming majority of nurses (97 percent) say they "worry" about medication errors, and more than two-thirds (68 percent) believe medication errors can be reduced with more consistent syringe labeling.

47.       Argentero PA, Zotti CM, Abbona F et al. [Regional surveillance of occupational percutaneous and mucocutaneous exposure to blood-borne pathogens in health care workers: strategies for prevention]. [Italian]. Medicina del Lavoro 2007; 98(2):145-155.
ABSTRACT: BACKGROUND: Several studies have investigated both the frequency and modality of occurrence of occupational exposure of health-care workers to blood-borne pathogens. At the moment no complete epidemiological data are available covering the hospitals of an entire Region. OBJECTIVES ANd METHODS: To describe the characteristics of mucocutaneous and percutaneous exposure to body fluids of the healthcare workers in 47 out of the 56 public hospitals (90% of a total 15,000 beds, 28,000 health-care workers full time equivalent) in Piedmont, Northern Italy (4.5 million inhabitants) over a three-year period (1999-2002), using SIROH (Studio Italiano Rischio Occupazionale da HIV) model to collect the data. RESULTS AND CONCLUSIONS: 5174 percutaneous injuries (12.7/100 beds) and 1724 mucocutaneous exposure (4.1/100 beds) were recorded. Surveillance data were similar to those collected in other multi-hospital studies. The variability of rates between hospitals was high, most likely due to the amount of underreporting. The categories most at risk of percutaneous and mucocutaneous exposure were, respectively, surgeons (9.3/100 surgeons) and midwives (2.9/100 midwives). Needles (syringe, winged steel, suture) were the medical devices most frequently involved in percutaneous injuries, 60% of which occurred after the use of such devices. Eighty-three per cent of healthcare workers had been HBV-vaccinated versus only 45% of cleaning staff. After percutaneous injuries with exposure to an HIV positive source only 40% of those exposed received post-exposure prophylaxis; in the case of mucocutaneous exposure the rate was 11%. We recorded 2 seroconversions following occupational exposure to an HCV positive source (risk of seroconversion: 0,2%). In order to implement preventive programmes the use of safety devices, an increase in the number of HBV-vaccinated contract workers, the use of chemoprophylaxis for HIV exposure, and the use of protective equipment are deemed necessary

48.       Arora A, Hakim I, Baxter J et al. Needle-free delivery of macromolecules across the skin by nanoliter-volume pulsed microjets. Proc Natl Acad Sci U S A 2007; 104(11):4255-4260.
ABSTRACT: Needle-free liquid jet injectors were invented >50 years ago for the delivery of proteins and vaccines. Despite their long history, needle-free liquid jet injectors are not commonly used as a result of frequent pain and bruising. We hypothesized that pain and bruising originate from the deep penetration of the jets and can potentially be addressed by minimizing the penetration depth of jets into the skin. However, current jet injectors are not designed to maintain shallow dermal penetration depths. Using a new strategy of jet injection, pulsed microjets, we report on delivery of protein drugs into the skin without deep penetration. The high velocity (v >100 m/s) of microjets allows their entry into the skin, whereas the small jet diameters (50-100 mum) and extremely small volumes (2-15 nanoliters) limit the penetration depth ( approximately 200 mum). In vitro experiments confirmed quantitative delivery of molecules into human skin and in vivo experiments with rats confirmed the ability of pulsed microjets to deliver therapeutic doses of insulin across the skin. Pulsed microjet injectors could be used to deliver drugs for local as well as systemic applications without using needles

49.       Askarian M, Memish ZA, Khan AA. Knowledge, practice, and attitude among Iranian nurses, midwives, and students regarding standard isolation precautions. Infection Control & Hospital Epidemiology 2007; 28(2):241-244.
ABSTRACT: Our goal was to assess the knowledge, attitudes, and practices regarding infection control and standard precautions among a group of nursing and midwifery instructors and students in Iran. A survey questionnaire was completed by 273 nursing and midwifery instructors and students at Shiraz University Medical Sciences during the period from May to November 2002. Two hundred thirty-one (90.9%) of the participants reported that they needed additional infection control education, especially on standard isolation precautions. There was a linear positive correlation between knowledge, practice, and attitude scores for the group of nursing, auxiliary nursing, and midwifery instructors, as well as their students (P<.05). Our study shows that there is an urgent need for evaluating education on infection control practices and standard precautions in general, as well as for structured infection control programs among nursing and midwifery staff

50.       Askarian M, Shaghaghian S, McLaws ML. Needlestick Injuries Among Nurses of Fars Province, Iran. Ann Epidemiol 2007.
ABSTRACT: PURPOSE: A prevalence survey was performed to estimate the magnitude and predictors for needlestick injury (NSI) in nurses of Fars province hospitals. METHODS: Questionnaires were distributed in 52 hospitals to a stratified random sample of 2118 (46.3%) nurses between April and September 2005 to collect self-reported NSI in the past 12- months. RESULTS: Of the 1555 nurses who returned a completed questionnaire, 49.6% (95% confidence interval [95 CI] 47.1%-52.1%) recalled at least one sharps injury, of which 52.6% were classified as NSI. Just over one fourth (26.3%; 95 CI 24.1%-28.6%, 409/1555) of respondents sustained at least one NSI, 75.6% (95 CI 71.1%-79.6%) recalled having sustained between 1 and 4 injuries in the past 12-months, of which 72.2% involved a hollow-bore needle and 95.1% of injuries involved fingers. Predictors of NSI included being a registered nurse (odds ratio [OR] 1.6, 95% CI 1.1-2.3) or midwife (OR 2.4, 95% CI 1.4-3.9) compared with nurse managers, being employed in a hospital located in other cities smaller than Shiraz (OR 1.4, 95% CI 1.1-1.8). Nurses who reported a previous contaminated NSI were less likely to sustain a further injury (OR 0.3, 95% CI 0.2-0.4). CONCLUSION: The prevalence of NSI in Iranian nurses is high, with the majority of injured staff having sustained up to 4 NSIs in a 12-month period. Nearly all NSIs were high-risk injuries involving a hollow-bore needle. Providing nursing staff with safety-engineered devices, including retractable syringes when hollow-bore needles are to be used, will be an important step toward reducing our NSI epidemic

51.       Askew SM. Occupational exposures to blood and body fluid: a study of medical students and health professions students in Virginia. AAOHN J 2007; 55(9):361-371.
ABSTRACT: Medical students and health professions students may be at high risk for occupational exposures to blood-borne pathogens. This retrospective chart review explored the rates and types of self-reported blood and body fluid exposures among medical students and health professions students at Eastern Virginia Medical School (EVMS), the University of Virginia School of Medicine, and Virginia Commonwealth University School of Medicine between January 1, 2001, and December 31, 2005, to determine an average rate of exposure reported by the student population at EVMS and in Virginia. Students at EVMS reported 126 exposures: 105 were needlestick and sharps injuries and 21 were blood and body fluid exposures. Fifty-one percent of the EVMS students reported not being the original user of the device causing their exposure. Students in Virginia reported 519 exposures. The majority of the exposures occurred in the operating room. Limitations of this study included student curricula not being reviewed and the medical schools' data collection methods not being compared. Student blood and body fluid exposures should be considered a serious and possibly deadly occupational hazard. Students must be deemed competent in basic health care procedures, universal precautions, and suturing techniques before being allowed to assist with or perform patient procedures

52.       Azar-Cavanagh M, Burdt P, Green-McKenzie J. Effect of the introduction of an engineered sharps injury prevention device on the percutaneous injury rate in healthcare workers. Infection Control & Hospital Epidemiology 2007; 28(2):165-170.
ABSTRACT: Objective. To evaluate the effect of introducing an engineered device for preventing injuries from sharp instruments (engineered sharps injury prevention device [ESIPD]) on the percutaneous injury rate in healthcare workers (HCWs).Methods. We undertook a controlled, interventional, before-after study during a period of 3 years (from January 1998 through December 2000) at a major medical center. The study population was HCWs with potential exposure to bloodborne pathogens. HCWs who sustain a needlestick injury are required by hospital policy to report the exposure. A confidential log of these injuries is maintained that includes information on the date and time of the incident, the type and brand of sharp device involved, and whether an ESIPD was used.Intervention. Introduction of an intravenous (IV) catheter stylet with a safety-engineered feature (a retractable protection shield), which was placed in clinics and hospital wards in lieu of other IV catheter devices that did not have safety features. No protective devices were present on suture needles during any of the periods. The incidence of percutaneous needlestick injury by IV catheter and suture needles was evaluated for 18 months before and 18 months after the intervention.Results. After the intervention, the incidence of percutaneous injuries resulting from IV catheters decreased significantly (P<.01), whereas the incidence of injuries resulting from suture needle injuries increased significantly (P<.008).Conclusion. ESIPDs lead to a reduction in percutaneous injuries in HCWs, helping to decrease HCWs' risk of exposure to bloodborne pathogens

53.       Bdour A, Altrabsheh B, Hadadin N, Al-Shareif M. Assessment of medical wastes management practice: a case study of the northern part of Jordan. Waste Management 2007; 27(6):746-759.
ABSTRACT: This study includes a survey of the procedures available, techniques, and methods of handling and disposing of medical waste at medium (between 100 and 200 beds) to large (over 200 beds) size healthcare facilities located in Irbid city (a major city in the northern part of Jordan). A total of 14 healthcare facilities, including four hospitals and 10 clinical laboratories, serving a total population of about 1.5 million, were surveyed during the course of this research. This study took into consideration both the quantity and quality of the generated wastes to determine generation rates and physical properties. Results of the survey showed that healthcare facilities in Irbid city have less appropriate practices when it comes to the handling, storage, and disposal of wastes generated in comparison to the developed world. There are no defined methods for handling and disposal of these wastes, starting from the personnel responsible for collection through those who transport the wastes to the disposal site. Moreover, there are no specific regulations or guidelines for segregation or classification of these wastes. This means that wastes are mixed, for example, wastes coming from the kitchen with those generated by different departments. Also, more importantly, none of the sites surveyed could provide estimated quantities of waste generated by each department, based upon the known variables within the departments. Average generation rates of total medical wastes in the hospitals were estimated to be 6.10 kg/patient/day (3.49 kg/bed/day), 5.62 kg/patient/day (3.14 kg/bed/day), and 4.02 kg/patient/day (1.88 kg/bed/day) for public, maternity, and private hospitals, respectively. For medical laboratories, rates were found to be in the range of 0.053-0.065 kg/test-day for governmental laboratories, and 0.034-0.102 kg/test-day for private laboratories. Although, based on the type of waste, domestic or general waste makes up a large proportion of the waste volume, so that if such waste is not mixed with patient derived waste, it can be easily handled. However, based on infections, it is important for healthcare staff to take precautions in handling sharps and pathological wastes, which comprises only about 26% of the total infectious wastes. Statistical analysis was conducted to develop mathematical models to aid in the prediction of waste quantities generated by the hospitals studied, or similar sites in the city that are not included in this study. In these models, the number of patients, number of beds, and hospital type were determined to be significant factors on waste generation. Such models provide decision makers with tools to better manage their medical waste, given the dynamic conditions of their healthcare facilities

54.       Bennett NJ, Bull AL, Dunt DR et al. Occupational exposures to bloodborne pathogens in smaller hospitals. Infection Control & Hospital Epidemiology 2007; 28(7):896-898.

55.       Bohannon J. The Freeing of the Tripoli Six. Discover 2007; November 2007:54-59-82.
ABSTRACT: I was in Tripoli, Lybia, wiping sweat off my forehead.  Sitting across from me in a back room of the Bulgarian embassy was a doctor named Zdravko Georgiev.  In 1999, he and his wife, a nurse, had been arrested along with four other Bulgarian nurses and a Palestinian medical intern.  They had been charged with bioterrorism, accused of intentionally infecting more than 400 children at a libyan hospital with HIV.  Georgiev, who had been working for a company on the other side of the country, had been released a few months earlier after having spent four years in prison, but the other medical workers, later dubbed the Tripoli Six, were waiting for death by a firing squad.

56.       Bowen S. Safety Sharp Solutions. Outpatient Surgery Magazine 2007; VIII Supplement(10):S40-S42.
ABSTRACT: Here's how and why you need to convinceyour staff to make the switch.  Have you incorporated the use of safety scalpels and blunt-tip suture needles:  If you have, is it properly documented in your Exposure Control Plan?  If you haven't, what's stopping you?  Your staff's safety is on the line.

57.       Brasel KJ, Mol C, Kolker A, Weigelt JA. Needlesticks and surgical residents: who is most at risk? J Surg Educ 2007; 64(6):395-398.
ABSTRACT: OBJECTIVE: Exposure to blood-borne diseases remains an occupational risk. Mandates have improved training in how to report exposures for all health-care workers. How exposure rates of surgical residents correlate with experience and mandatory training to reduce risk is not known. It was hypothesized that enhanced training would result in an increased reporting of exposures by surgical trainees and that risk would be greater in the first years of training. DESIGN: Retrospective review of occupational health records and operative case logs, prospective survey. METHODS: Occupational Health Services provides both initial and annual training to General Surgery house staff at the Medical College of Wisconsin. Initial training consists of a blood-borne pathogen review and a detailed explanation of exposure reporting. Mandatory annual training is provided during Surgical Grand Rounds. Training was enhanced beginning June 2005 using a videotape outlining surgical risks and specific countermeasures. The numbers of reported exposures per year before and after enhanced training were compared. Exposures were self-reported. As most exposures occurred in the operating room, rate of exposure was calculated for each year of training using the total number of cases done each year reported by the general surgical residents. RESULTS: Surgical residents reported 118 needlestick injuries over 6 years. Senior and chief residents demonstrated a significantly lower exposure rate than junior residents (nonparametric Mood's median test, p < 0.0001). No significant difference in the injury rate was found per 1000 cases after enhanced training. CONCLUSIONS: Increasing surgical experience lowered the needlestick injury rate. Assuming no change in self-reporting rates by year, enhanced training and reporting guidelines did not seem to change risk. More specific training for junior residents, as well as passive prevention solutions, may be necessary to positively impact their exposure risk

58.       Casey AL, Elliott TS. The usability and acceptability of a needleless connector system. Br J Nurs 2007; 16(5):267-271.
ABSTRACT: Needleless connectors were introduced into clinical practice to reduce the rate of needlestick injuries to healthcare workers (HCWs). There have, however, been limited reports of user acceptability of these devices. The usability and acceptability of the Clearlink needleless connector (Baxter Healthcare, UK) was therefore completed by HCWs at University Hospital Birmingham NHS Foundation Trust following a 12-month clinical evaluation. Seventy percent (28/40) of HCWs reported that they would prefer to use Clearlink needleless connectors rather than conventional luers caps, 15% (6/40) would use either, and only 15% (6/40) preferred to use luer caps. In total, 85% of HCWs reported that Clearlink was acceptable to use in the clinical situation. The results demonstrate that comprehensive training and technical support both before and after new device implementation were essential to ensure a smooth transition

59.       Catanzarite V, Byrd K, McNamara M, Bombard A. Preventing needlestick injuries in obstetrics and gynecology: how can we improve the use of blunt tip needles in practice? Obstet Gynecol 2007; 110(6):1399-1403.
ABSTRACT: Surgical needlestick injuries are common in obstetrics and gynecology and can cause transmission of viral diseases including hepatitis and acquired immunodeficiency syndrome (AIDS). Strategies to reduce the rate of needlestick injuries include using instruments rather than fingers to retract tissue and grasp needles, double gloving, using surgical staplers for skin closure, and substituting blunt tip surgical needles for sharp tip needles where applicable. Studies have shown the use of blunt tip surgical needles to be remarkably effective in reducing needlestick injuries. Despite recommendations by the American College of Surgeons that blunt tip surgical needles be used routinely, at least for fascial closure, and by the Occupational Safety and Health Administration and the National Institute for Occupational Health and Safety that these devices be used whenever medically appropriate, use in obstetrics and gynecology appears to be limited. Potential barriers to use include availability, the "feel" of the needle as it penetrates tissue, and habit. We suggest that blunt tip surgical needles have the potential to replace traditional needles for many obstetric and gynecologic applications. If their use is to become more widespread, we must focus on availability, evaluation for specific applications, and physician education

60.       Charles Morse and Stuart Colburn (Defendant). Christus Health/St. Joseph Hospital v. Angela Price. 01-05-00210-CV.  2-2-2007.  Texas Court of Appeals for the First District on appeal from the 268th District Court, Fort Bend County.
ABSTRACT: Appellant, Christus Health/St. Joseph Hospital, appeals a judgement infavor of appellee, Angela Price, that was entered in accordance with the jury's verdict.  The hospital sued Priced to attempt to reverse a determination by the Texas Workers' Compensation Commission (TWCC), which had found that Price sustained a compensable injury in the course and scope of her employment with the hospital.  The sole issue submitted to the jury was whether Price had received a compensable injury.  The jury agreed with the determination by the TWCC.  The trial court rendered judgement that the hospital take nothing in its suit against Price and awarded Price her attorney's fees and costs before the trail court and appellate attorney's fees in the event of an unsuccessful appeal by the hospital.  In three issues, the hospital contends that (1) the trail court erred by excluding medical records obtained by a deposition on written questions, (2) the trail court erred by allowing Price's expert witness to tesitfy, and (3) the evidence was legally and factually insufficent to support the jury's verdict that Price sustained a compensable injury.  We affirm the judgement of the trial court.

61.       Charney W, Schirmer J. Nursing injury rates and negative patient outcomes--connecting the dots. AAOHN J 2007; 55(11):470-475.
ABSTRACT: The connection between nursing injury rates and patient outcomes has not been totally grasped in the health care occupational health setting. This article concludes that nursing injury rates are linked to the nursing shortage and less nursing time at the bedside, both of which have been scientifically linked to negative patient outcomes. Because nurses' working conditions affect patients' outcomes, more funding and changes are needed to improve these conditions

62.       Chen GX, Jenkins EL. Potential work-related bloodborne pathogen exposures by industry and occupation in the United States part I: an emergency department-based surveillance study. Am J Ind Med 2007; 50(3):183-190.
ABSTRACT: BACKGROUND: Since the early 1990s, researchers have attempted to assess the magnitude of potential work-related bloodborne pathogen (BBP) exposures in the U.S. The only data-derived estimate of 385,000 needlestick and other sharps injuries per year was reported in 2004. The estimate was derived from a convenience sample and did not include exposures outside of hospitals. This study seeks to understand the magnitude and distribution of the exposures across all industries and occupations. METHODS: Data were from the 1998 to 2000 National Electronic Injury Surveillance System (NEISS), a stratified probability-based sample of U.S. hospital emergency departments (EDs). NEISS covers all industries and occupations. National estimates of exposures and exposure rates (the number of exposures/1,000 full-time equivalents (FTE)) were computed. RESULTS: An estimated 78,100 potential work-related exposures to BBP were treated in hospital EDs annually in the U.S. While hospitals accounted for 75% of all these exposures, 11 other industries had a substantial number of exposures. While registered nurses accounted for 36% of all exposures, 13 other occupations had a substantial number of exposures. Hospitals had the highest exposure rate of 11.3/1,000 FTE, followed by nursing homes (2.8), and residential care facilities without nursing (1.9). Registered nurses had the highest exposure rate of 15.3/1,000 FTE, followed by clinical laboratory technologists and technicians (13.9), and physicians (7.1). CONCLUSIONS: While this study begins to more completely describe the problem of potential BBP exposure in the workplace, it is but a first step in further understanding the complex issues surrounding workplace BBP exposures

63.       Chen GX, Jenkins EL. Potential work-related exposures to bloodborne pathogens by industry and occupation in the United States Part II: A telephone interview study. American Journal of Industrial Medicine 2007; 50(4):285-292.
ABSTRACT: BACKGROUND: The companion surveillance portion of this study [Chen and Jenkins, 2007] reported the frequency and rate of potential work-related exposures to bloodborne pathogens (BBP) treated in emergency departments (EDs) by industry and occupation, but it lacks details on the circumstances of the exposure and other relevant issues such as BBP safety training, use of personal protective equipment (PPE) or safety needles, or reasons for seeking treatment in a hospital ED. METHODS: Telephone interviews were conducted with workers who had been treated in EDs for potential work-related exposures to BBP in 2000-2002. Respondents were drawn from the National Electronic Injury Surveillance System. RESULTS: Of the 593 interviews, 382 were from hospitals, 51 were from emergency medical service/firefighting (EMS/FF), 86 were from non-hospital healthcare settings (e.g., nursing homes, doctors' offices, home healthcare providers, etc.), 22 were from law enforcement (including police and correctional facilities), and 52 were from other non-healthcare settings (i.e., schools, hotels, and restaurants). Needlestick/sharps injuries were the primary source of exposure in hospitals and non-hospital healthcare settings. Skin and mucous membrane was the primary route of exposure in EMS/FF. Human bites accounted for a significant portion of the exposures in law enforcement and other non-healthcare settings. In general, workers from non-hospital settings were less likely to use PPE, to have BBP safety training, to be aware of the BBP standards and exposure treatment procedures, and to report or seek treatment for a work-related exposure compared to hospital workers. CONCLUSIONS: This study suggests that each industry group has unique needs that should be addressed

64.       Clarke SP. Hospital work environments, nurse characteristics, and sharps injuries. Am J Infect Control 2007; 35(5):302-309.
ABSTRACT: BACKGROUND: A growing body of research links working conditions, such as staffing levels and work environment characteristics, with safety for both patients and workers in health care settings, including sharps injuries in hospital staff nurses. METHODS: Surveys of 11,516 staff nurses from 188 Pennsylvania general acute care hospitals in 1999 were analyzed. Hospital work environments, measured using the Practice Environment Scales of the Nursing Work Index--Revised, and staffing were tested as predictors of experiencing at least one sharps injury in the preceding year, both before and after controlling for nurse risk factors, use of safety-engineered devices, and hospital structural characteristics. RESULTS: Nurses with less than 5 years of experience, perioperative nurses, and those performing routine venipuncture for blood draws were more likely to be injured. Nurses working in hospitals with the most favorable working environments were one-third less likely to be injured. Staffing levels were not associated with sharps injuries. CONCLUSIONS: Across a large state, nurses working in acute care hospitals with better practice environments had fewer sharps injuries. Work environment conditions and specialty- and setting-specific risk factors deserve continued attention in sharps injury research

65.       Clarke SP, Schubert M, Korner T. Sharp-device injuries to hospital staff nurses in 4 countries. Infect Control Hosp Epidemiol 2007; 28(4):473-478.
ABSTRACT: OBJECTIVE: To compare sharp-device injury rates among hospital staff nurses in 4 Western countries. DESIGN: Cross-sectional survey. SETTING: Acute-care hospital nurses in the United States (Pennsylvania), Canada (Alberta, British Columbia, and Ontario), the United Kingdom (England and Scotland), and Germany. PARTICIPANTS: A total of 34,318 acute-care hospital staff nurses in 1998-1999. RESULTS: Survey-based rates of retrospectively-reported needlestick injuries in the previous year for medical-surgical unit nurses ranged from 146 injuries per 1,000 full-time equivalent positions (FTEs) in the US sample to 488 injuries per 1,000 FTEs in Germany. In the United States and Canada, very high rates of sharp-device injury among nurses working in the operating room and/or perioperative care were observed (255 and 569 injuries per 1,000 FTEs per year, respectively). Reported use of safety-engineered sharp devices was considerably lower in Germany and Canada than it was in the United States. Some variation in injury rates was seen across nursing specialties among North American nurses, mostly in line with the frequency of risky procedures in the nurses' work. CONCLUSIONS: Studies conducted in the United States over the past 15 years suggest that the rates of sharp-device injuries to front-line nurses have fallen over the past decade, probably at least in part because of increased awareness and adoption of safer technologies, suggesting that regulatory strategies have improved nurse safety. The much higher injury rate in Germany may be due to slow adoption of safety devices. Wider diffusion of safer technologies, as well as introduction and stronger enforcement of occupational safety and health regulations, are likely to decrease sharp-device injury rates in various countries even further

66.       Cleveland JL, Barker LK, Cuny EJ, Panlilio AL, National Surveillance System for Health Care Workers Group. Preventing percutaneous injuries among dental health care personnel. Journal of the American Dental Association 2007; 138(2):169-178.
ABSTRACT: BACKGROUND: The Occupational Safety and Health Administration and the Centers for Disease Control and Prevention (CDC) recommend that health care personnel (HCP) adopt safer work practices and consider using medical devices with safety features. This article describes the circumstances of percutaneous injuries among a sample of hospital-based dental HCP and estimates the preventability of a subset of these injuries: needlesticks. METHODS: The authors analyzed percutaneous injuries reported by dental HCP in the CDC's National Surveillance System for Health Care Workers (NaSH) from December 1995 through August 2004 to describe the circumstances. RESULTS: Of 360 percutaneous injuries, 36 percent were reported by dentists, 34 percent by oral surgeons, 22 percent by dental assistants, and 4 percent each by hygienists and students. Almost 25 percent involved anesthetic syringe needles. Of 87 needlestick injuries, 53 percent occurred after needle use and during activities in which a safety feature could have been activated (such as during passing and handling) or a safer work practice used. CONCLUSIONS: NaSH data show that needlestick injuries still occur and that a majority occur at a point in the workflow at which safety syringes--in addition to safe work practices and recapping systems--could contribute to injury prevention. CLINICAL IMPLICATIONS: All dental practices should have a comprehensive written program for preventing needlestick injuries that describes procedures for identifying, screening and, when appropriate, adopting safety devices; mechanisms for reporting and providing medical follow-up for percutaneous injuries; and a system for training staff members in safe work practices and the proper use of safety devices

67.       Cleveland JL, Barker LK, Cuny EJ, Panlilio AL. Preventing percutaneous injuries among dental health care personnel. J Am Dent Assoc 2007; 138(2):169-178.
ABSTRACT: BACKGROUND: The Occupational Safety and Health Administration and the Centers for Disease Control and Prevention (CDC) recommend that health care personnel (HCP) adopt safer work practices and consider using medical devices with safety features. This article describes the circumstances of percutaneous injuries among a sample of hospital-based dental HCP and estimates the preventability of a subset of these injuries: needlesticks. METHODS: The authors analyzed percutaneous injuries reported by dental HCP in the CDC's National Surveillance System for Health Care Workers (NaSH) from December 1995 through August 2004 to describe the circumstances. RESULTS: Of 360 percutaneous injuries, 36 percent were reported by dentists, 34 percent by oral surgeons, 22 percent by dental assistants, and 4 percent each by hygienists and students. Almost 25 percent involved anesthetic syringe needles. Of 87 needlestick injuries, 53 percent occurred after needle use and during activities in which a safety feature could have been activated (such as during passing and handling) or a safer work practice used. CONCLUSIONS: NaSH data show that needlestick injuries still occur and that a majority occur at a point in the workflow at which safety syringes--in addition to safe work practices and recapping systems--could contribute to injury prevention. CLINICAL IMPLICATIONS: All dental practices should have a comprehensive written program for preventing needlestick injuries that describes procedures for identifying, screening and, when appropriate, adopting safety devices; mechanisms for reporting and providing medical follow-up for percutaneous injuries; and a system for training staff members in safe work practices and the proper use of safety devices

68.       Connell J, Zurn P, Stilwell B, Awases M, Braichet JM. Sub-Saharan Africa: beyond the health worker migration crisis? Soc Sci Med 2007; 64(9):1876-1891.
ABSTRACT: Migration of skilled health workers from sub-Saharan African countries has significantly increased in this century, with most countries becoming sources of migrants. Despite the growing problem of health worker migration for the effective functioning of health care systems there is a remarkable paucity and incompleteness of data. Hence, it is difficult to determine the real extent of migration from, and within, Africa, and thus develop effective forecasting or remedial policies. This global overview and the most comprehensive data indicate that the key destinations remain the USA and the UK, and that major sources are South Africa and Nigeria, but in both contexts there is now greater diversity. Migrants move primarily for economic reasons, and increasingly choose health careers because they offer migration prospects. Migration has been at considerable economic cost, it has depleted workforces, diminished the effectiveness of health care delivery and reduced the morale of the remaining workforce. Countries have sought to implement national policies to manage migration, mitigate its harmful impacts and strengthen African health care systems. Recipient countries have been reluctant to establish effective ethical codes of recruitment practice, or other forms of compensation or technology transfer, hence migration is likely to increase further in the future, diminishing the possibility of achieving the United Nations millennium development goals and exacerbating existing inequalities in access to adequate health care

69.       Cutter J, Gammon J. Review of standard precautions and sharps management in the community. Br J Community Nurs 2007; 12(2):54-60.
ABSTRACT: Standard precautions are imperative for staff and patient safety and provide a basis for sound infection control practice in all health-care settings. One key element of these precautions relates to the safe handling and management of sharps to prevent occupational acquisition of blood-borne viral infection. Many inoculation injuries could be avoided by following standard precautions whenever contact with blood or body fluids is anticipated. However, evidence suggests that compliance with standard precautions is inadequate. With the modernization of the health service in the UK, community health care is becoming more complex, potentially increasing the risk of inoculation injury to community nurses. Although compliance with standard precautions in hospitals is well documented, there is limited research specific to community nurses. This review examines compliance with standard precautions by community nurses and discusses some strategies aimed at improving compliance with one of the key elements of standard precautions, i.e. sharps management

70.       Damani N. Simple measures save lives: an approach to infection control in countries with limited resources. [Review] [19 refs]. Journal of Hospital Infection 2007; 65(S2):151-154.
ABSTRACT: It has been estimated that in developed countries up to 10% of hospitalized patients develop infections every year.  The risk of healthcare-associated infections (HAI) in developing countries is 2-20 times higher than in developed countries and it has been estimated that more than 40% of these infections are preventable.

71.       David HT, Aminzadeh KK, Kae AH, Radomsky SC. Instrument retraction to avoid needle-stick injuries during intraoral local anesthesia. Oral Surgery Oral Medicine Oral Pathology Oral Radiology & Endodontics 2007; 103(3):e11-e13.
ABSTRACT: We present a new retraction technique for the intraoral injection of a local anesthetic. This approach eliminates the hazards associated with needle-stick injuries during the injection procedure

72.       Davies CG, Khan MN, Ghauri AS, Ranaboldo CJ. Blood and body fluid splashes during surgery--the need for eye protection and masks. Ann R Coll Surg Engl 2007; 89(8):770-772.
ABSTRACT: INTRODUCTION: While most surgeons make an effort to avoid needlestick injury, some can pay little attention to reduce the potential route of infection occurring when body fluids splash into the eye. It has been shown that transmission of HIV, hepatitis B or C can occur across any mucous membrane. This study aims to quantify how frequently body fluids splash the mask and lens of wrap around protective glasses thus potentially exposing the surgeon to infection. PATIENTS AND METHODS: A prospective study was carried out by a single surgeon on all cases performed over a 1-year period. Protective mask and glasses were examined before and after operations. RESULTS: A total of 384 operations were performed with 174 (45%) showing blood or body fluid splash on the lens. A high incidence of splashes was found in vascular surgical procedures (79%). All amputations showed splash on the protective lens. Interestingly, 50% of laparoscopic cases resulted in blood or body fluid splash on the protective lens. CONCLUSIONS: This study has shown a high incidence (45%) of blood and body fluid splashes found on protective glasses and masks. There was a very high incidence (79%) during vascular surgical procedures. With the prevalence of HIV and hepatitis increasing, it seems prudent to protect oneself against possible routes of transmission

73.       Davis LK, DeMaria A, Jr. Sharps Injuries among Hospital Workers in Massachusetts, 2004: Findings from the Massachusetts Sharps Injury Surveillance System.  2007.
ABSTRACT: Executive Summary: Health care worker exposures to bloodborne pathogens as a result of injuries caused by needles and other sharp devices are a significant public health concern.  The U.S. Centers for Disease Control and Prevention (CDC) estimate that, nationwide, between 600,000 and 800,000 percutaneous injuries from contaminated sharp devices occur each year in health care; approximately half are sustained by hospital workers.

Sharps injuries are preventable, and health care facilities are required by state and federal regulations to implement comprehensive plans to reduce these injuries.  Elements of a successful sharps injury prevention program (as outlined by the CDC) include: promoting an overall cuulture of safety in the workplace, eliminating the unnecessary use of needles and other sharp devices, using devices with sharps injury prevention features (safety devices), employing safe workplace practices, and training health care personnel.  Sharps injury surveillance is also a key component of a comprehensive program.

74.       Doi SA, Amigo MF. Nurses' intentions to wear gloves during venipuncture procedures: a behavioral psychology perspective. Infection Control & Hospital Epidemiology 2007; 28(6):747-750.
ABSTRACT: Registered nurses working at a teaching hospital in Kuwait were surveyed to assess the psychosocial variables associated with their intention to comply with glove-wearing recommendations. Perceived consequences and normative beliefs, as well as sex and years of nursing experience, significantly influenced their behavioral intentions, suggesting that improvements in intention to comply are more likely to come from practical demonstrations that show nurses the potential outcomes of both using and not using gloves

75.       Falagas ME, Karydis I, Kostogiannou I. Percutaneous exposure incidents of the health care personnel in a newly founded tertiary hospital: a prospective study. PLoS ONE 2007; 2:e194.
ABSTRACT: BACKGROUND: Percutaneous exposure incidents (PEIs) and blood splashes on the skin of health care workers are a major concern, since they expose susceptible employees to the risk of infectious diseases. We undertook this study in order to estimate the overall incidence of such injuries in a newly founded tertiary hospital, and to evaluate possible changes in their incidence over time. METHODOLOGY/PRINCIPAL FINDINGS: We prospectively studied the PEIs and blood splashes on the skin of employees in a newly founded (October 2000) tertiary hospital in Athens, Greece, while a vaccination program against hepatitis B virus, as well as educational activities for avoidance of injuries, were taking place. The study period ranged from October 1, 2002 to February 28, 2005. Serologic studies for hepatitis B (HBV) and C virus (HCV) as well as human immunodeficiency virus (HIV) were performed in all injured employees and the source patients, when known. High-titer immunoglobulin (250 IU anti-HBs intramuscularly) and HBV vaccination were given to non-vaccinated or previously vaccinated but serologically non-responders after exposure. Statistical analysis of the data was performed using Mc Nemar's and Fisher's tests. 60 needlestick, 11 sharp injuries, and two splashes leading to exposure of the skin or mucosa to blood were reported during the study period in 71 nurses and two members of the cleaning staff. The overall incidence (percutaneous injuries and splashes) per 100 full-time employment-years (100 FTEYs) for high-risk personnel (nursing, medical, and cleaning staff) was 3.48, whereas the incidence of percutaneous injuries (needlestick and sharp injuries) alone per 100 FTEYs was 3.38. A higher incidence of injuries was noted during the first than in the second half of the study period (4.67 versus 2.29 per 100 FTEYs, p = 0.005). No source patient was found positive for HCV or HIV. The use of high-titer immunoglobulin after adjustment for the incidence of injuries was higher in the first than in the second half of the study period, although the difference was not statistically significant [9/49 (18.37%) vs 1/24 (4.17%), p = 0.15]. CONCLUSIONS/SIGNIFICANCE: Our data show that nurses are the healthcare worker group that reports most of PEIs. Doctors did not report such injuries during the study period in our setting. However, the possibility of even relatively frequent PEIs in doctors cannot be excluded. This is due to underreporting of such events that has been previously described for physicians and surgeons. A decrease of the incidence of PEIs occurred during the operation of this newly founded hospital

76.       Fisman DN, Harris AD, Rubin M, Sorock GS, Mittleman MA. Fatigue increases the risk of injury from sharp devices in medical trainees: results from a case-crossover study. Infection Control & Hospital Epidemiology 2007; 28(1):10-17.
ABSTRACT: Background. Extreme fatigue in medical trainees likely compromises patient safety, but regulations that limit trainee work hours have been controversial. It is not known whether extreme fatigue compromises trainee safety in the healthcare workplace, but evidence of such a relationship would inform the current debate on trainee work practices. Our objective was to evaluate the relationship between fatigue and workplace injury risk among medical trainees and nontrainee healthcare workers.Design. Case-crossover study.Setting. Five academic medical centers in the United States and Canada.Participants. Healthcare workers reporting to employee healthcare clinics for evaluation of needlestick injuries and other injuries related to sharp instruments and devices (sharps injuries). Consenting workers completed a structured interview about work patterns, time at risk of injury, and frequency of fatigue.Results. Of 350 interviewed subjects, 109 (31%) were medical trainees. Trainees worked more hours per week (P<.001) and slept less the night before an injury (P<.001) than did other healthcare workers. Fatigue increased injury risk in the study population as a whole (incidence rate ratio [IRR], 1.40 [95% confidence interval {CI}, 1.03-1.90]), but this effect was limited to medical trainees (IRR, 2.94 [95% CI, 1.71-5.07]) and was absent for other healthcare workers (IRR, 0.97 [95% CI, 0.66-1.42]) (P=.001).Conclusions. Long work hours and sleep deprivation among medical trainees result in fatigue, which is associated with a 3-fold increase in the risk of sharps injury. Efforts to reduce trainee work hours may result in reduced risk of sharps-related injuries among this group

77.       Ganczak M, Barss P, Al-Marashda A, Al-Marzouqi A, Al-Kuwaiti N. Use of the Haddon matrix as a tool for assessing risk factors for sharps injury in emergency departments in the United Arab Emirates. Infection Control & Hospital Epidemiology 2007; 28(6):751-754.
ABSTRACT: We investigated the epidemiology and prevention of sharps injuries in the United Arab Emirates. Among 82 emergency nurses and 38 doctors who responded to our questionnaire, risk factors for sharp device injuries identified using the Haddon matrix included personal factors (for the pre-event phase, a lack of infection control training, a lack of immunization, and recapping needles, and for the postevent phase, underreporting of sharps injuries) and equipment-related factors (for the pre-event phase, failure to use safe devices; for the event phase, failure to use gloves in all appropriate situations). Nearly all injuries to doctors were caused by suture needles, and among nurses more than 50% of injuries were caused by hollow-bore needles

78.       Gershon RR, Sherman M, Mitchell C et al. Prevalence and risk factors for bloodborne exposure and infection in correctional healthcare workers. Infection Control & Hospital Epidemiology 2007; 28(1):24-30.
ABSTRACT: Objective. To determine the prevalence and risk factors for bloodborne exposure and infection in correctional healthcare workers (CHCWs).Design. Cross-sectional risk assessment study with a confidential questionnaire and serological testing performed during 1999-2000.Setting. Correctional systems in 3 states.Results. Among 310 participating CHCWs, the rate of percutaneous injury (PI) was 32 PIs per 100 person-years overall and 42 PIs per 100 person-years for CHCWs with clinical job duties. Underreporting was common, with only 25 (49%) of 51 PIs formally reported to the administration. Independent risk factors for experiencing PI included being age 45 or older (adjusted odds ratio [aOR], 2.41 [95% confidence interval (CI), 1.31-4.46]) and having job duties that involved needle contact (aOR, 3.70 [95% CI, 1.28-10.63]) or blood contact (aOR, 5.05 [95% CI, 1.45-17.54]). Overall, 222 CHCWs (72%) reported having received a primary hepatitis B vaccination series; of these, 150 (68%) tested positive for anti-hepatitis B surface antigen, with negative results significantly associated with receipt of last dose more than 5 years previously. Serologic markers of hepatitis B virus infection were identified in 31 individuals (10%), and the prevalence of hepatitis C virus infection was 2% (n=7). The high hepatitis B vaccination rate limited the ability to identify risk factors for infection, but hepatitis C virus infection correlated with community risk factors only.Conclusion. Although the wide coverage with hepatitis B vaccination and the decreasing rate of hepatitis C virus infection in the general population are encouraging, the high rate of exposure in CHCWs and the lack of exposure documentation are concerns. Continued efforts to develop interventions to reduce exposures and encourage reporting should be implemented and evaluated in correctional healthcare settings. These interventions should address infection control barriers unique to the correctional setting

79.       Gershon RR, Qureshi KA, Pogorzelska M et al. Non-hospital based registered nurses and the risk of bloodborne pathogen exposure. Ind Health 2007; 45(5):695-704.
ABSTRACT: The aim of this study was to assess the risk of blood and body fluid exposure among non-hospital based registered nurses (RNs) employed in New York State. The study population was mainly unionized public sector workers, employed in state institutions. A self-administered questionnaire was completed by a random stratified sample of members of the New York State Nurses Association and registered nurse members of the New York State Public Employees Federation. Results were reviewed by participatory action research (PAR) teams to identify opportunities for improvement. Nine percent of respondents reported at least one needlestick injury in the 12-month period prior to the study. The percutaneous injury (PI) rate was 13.8 per 100 person years. Under-reporting was common; 49% of all PIs were never formally reported and 70% never received any post-exposure care. Primary reasons for not reporting included: time constraints, fear, and lack of information on reporting. Significant correlates of needlestick injuries included tenure, patient load, hours worked, lack of compliance with standard precautions, handling needles and other sharps, poor safety climate, and inadequate training and availability of safety devices (p<0.05). PAR teams identified several risk reduction strategies, with an emphasis on safety devices. Non-hospital based RNs are at risk for bloodborne exposure at rates comparable to hospital based RNs; underreporting is an important obstacle to infection prevention, and primary and secondary risk management strategies appeared to be poorly implemented. Intervention research is warranted to evaluate improved risk reduction practices tailored to this population of RNs

80.       Gisselquist D. How much do blood exposures contribute to HIV prevalence in female sex workers in sub-Saharan Africa, Thailand and India? International Journal of STD & AIDS 2007; 18(9):581-588.
ABSTRACT: Female sex workers (FSWs) are subject to frequent invasive procedures in health care and cosmetic services. When infection control is deficient, these procedures not only put FSWs at risk to acquire HIV, but are also risks for FSWs to transmit HIV to the general population. Direct information about blood exposures other than injection drug use as risks for HIV infection in FSWs has been too limited to test the hypothesis that unsterile health-care procedures have infected large numbers of FSWs in sub-Saharan Africa and Asia. However, indirect evidence suggests that blood exposures might account for an important proportion of their HIV infections. This indirect evidence includes: higher prevalence of hepatitis C infection among sex workers than among other women; continuing HIV acquisition among FSWs despite high rates of condom use and surprisingly high ratios of incidence of HIV compared with incidence of syphilis, gonorrhoea and chlamydia

81.       Gold K, Schumann J. Dangers of used sharps in household trash: implications for home care. Home Healthc Nurse 2007; 25(9):602-607.
ABSTRACT: Between 8 and 9 million Americans are self-injecting medication at home, and the majority of the needles used are being thrown into the household trash. It is up to all stakeholders, including healthcare professionals, to help change the way these dangerous needles and other sharps are discarded. Are you giving your patients the correct information?

82.       Green-McKenzie J, Shofer FS. Duration of time on shift before accidental blood or body fluid exposure for housestaff, nurses, and technicians. Infection Control & Hospital Epidemiology 2007; 28(1):5-9.
ABSTRACT: Background. Shift work has been found to be associated with an increased rate of errors and accidents among healthcare workers (HCWs), but the effect of shift work on accidental blood and body fluid exposure sustained by HCWs has not been well characterized.Objectives. To determine the duration of time on shift before accidental blood and body fluid exposure in housestaff, nurses, and technicians and the proportion of housestaff who sustain a blood and body fluid exposure after 12 hours on duty.Methods. This retrospective, descriptive study was conducted during a 24-month period at a large urban teaching hospital. Participants were HCWs who sustained an accidental blood and body fluid exposure.Results. Housestaff were on duty significantly longer than both nursing staff (P=.02) and technicians (P<.0001) before accidental blood and body fluid exposure. Half of the blood and body fluid exposures sustained by housestaff occurred after being on duty 8 hours or more, and 24% were sustained after being on duty 12 hours or more. Of all HCWs, 3% reported an accidental blood and body fluid exposure, with specific rates of 7.9% among nurses, 9.4% among housestaff, and 3% among phlebotomists.Conclusions. Housestaff were significantly more likely to have longer duration of time on shift before blood and body fluid exposure than were the other groups. Almost one-quarter of accidental blood and body fluid exposures to housestaff were incurred after they had been on duty for 12 hours or more. Housestaff sustained a higher rate of accidental blood and body fluid exposures than did nursing staff and technicians

83.       Gurley ES, Montgomery JM, Hossain MJ et al. Risk of nosocomial transmission of nipah virus in a Bangladesh hospital. Infection Control & Hospital Epidemiology 2007; 28(6):740-742.
ABSTRACT: We conducted a seroprevalence study and exposure survey of healthcare workers to assess the risk of nosocomial transmission of Nipah virus during an outbreak in Bangladesh in 2004. No evidence of recent Nipah virus infection was detected despite substantial exposures and minimal use of personal protective equipment

84.       Hecht N, Wettan S. Percutaneous injuries. J Am Dent Assoc 2007; 138(5):574.

85.       Heneghan C, Perera R. Prevention of hepatitis C in Japan: a lesson for us all. Lancet 2007; 370(9604):1982-1983.

86.       Hu T, Li G, Zuo Y, Zhou X. Risk of Hepatitis B Virus Transmission via Dental Handpieces and Evaluation of an Antisuction Device for Prevention of Transmission. Infection Control & Hospital Epidemiology 2007; 28(1):80-82.
ABSTRACT: We evaluated the risk of hepatitis B virus (HBV) transmission via dental handpieces and the effects of an antisuction device in preventing HBV contamination. The results of our study show that under certain conditions, HBV transmission can occur when an antisuction device is used during dental procedures. We conclude that such devices may decrease contamination, but do not eliminate it

87.       Huber MA, Terezhalmy GT. HIV: infection control issues for oral healthcare personnel. [Review] [55 refs]. Journal of Contemporary Dental Practice [Electronic Resource] 2007; 8(3):1-12.
ABSTRACT: AIM: To present the essential elements of an infection control/exposure control plan in the oral healthcare setting with emphasis on HIV infection. METHODS AND MATERIALS: A comprehensive review of the literature was conducted with special emphasis on HIV-related infection control issues in the oral healthcare setting. RESULTS: Currently available knowledge related to HIV-related infection control issues is supported by data derived from well-conducted trials or extensive, controlled observations, or, in the absence of such data, by best-informed, most authoritative opinion available. CONCLUSION: Essential elements of an effective HIV-related infection control plan include: (1) education and training related to the etiology and epidemiology of HIV infection and exposure prevention; (2) plans for the management of oral healthcare personnel potentially exposed to HIV and for the follow-up of oral healthcare personnel exposed to HIV; and (3) a policy for work restriction of HIV-positive oral healthcare personnel. CLINICAL SIGNIFICANCE: While exposure prevention remains the primary strategy for reducing occupational exposure to HIV, knowledge about potential risks and concise written procedures that promote a seamless response following occupational exposure can greatly reduce the emotional impact of an accidental needlestick injury. [References: 55]

88.       Ismail NA, boul Ftouh AM, El-Shoubary WH, Mahaba H. Safe injection practice among health-care workers in Gharbiya Governorate, Egypt. East Mediterr Health J 2007; 13(4):893-906.
ABSTRACT: We assessed safe injection practices among 1100 health-care workers in 25 health-care facilities in Gharbiya Governorate. Questionnaires were used to collect information and 278 injections were observed using a standardized checklist. There was a lack of infection control policies in all the facilities and a lack of many supplies needed for safe injection. Proper needle manipulation before disposal was observed in only 41% of injections, safe needle disposal in 47.5% and safe syringe disposal in 0%. Reuse of used syringes and needles was reported by 13.2% of the health-care workers and 66.2% had experienced a needle-stick injury. Only 11.3% had received a full course of hepatitis B vaccination

89.       Jagger J. Caring for Heathcare Workers: A Global Perspective. Infection Control & Hospital Epidemiology 2007; 28(1):-4.
ABSTRACT: This issue of the journal reflects broadly upon the risks of bloodborne pathogen exposure--risks faced by healthcare workers (HCWs) everywhere.  The article covers an array of issues, including the impact of work schedules, healthcare settings, culture-specific practices, and the implementation of safety-engineered sharp devices on the occupational risk of injuries from sharp devices and blood contact.  It is a fitting occasion to reflect on the state of the art in providing a safe working environment for HCWs and to consider a future path towards equitable access to its basic element.

90.       Janjua NZ, Razaq M, Chandir S, Rozi S, Mahmood B. Poor knowledge--predictor of nonadherence to universal precautions for blood borne pathogens at first level care facilities in Pakistan. BMC Infectious Diseases 2007; 7:81.
ABSTRACT: BACKGROUND: We conducted an assessment of knowledge about blood borne pathogens (BBP) and use of universal precautions at first level care facilities (FLCF) in two districts of Pakistan. METHODS: We conducted a cross-sectional survey and selected three different types of FLCFs ; public, general practitioners and unqualified practitioners through stratified random sampling technique. At each facility, we interviewed a prescriber, a dispenser, and a housekeeper for knowledge of BBPs transmission and preventive practices, risk perception, and use of universal precautions. We performed multiple linear regression to assess the effect of knowledge score (11 items) on the practice of universal precautions score (4 items- use of gloves, gown, needle recapping, and HBV vaccination). RESULTS: We interviewed 239 subjects. Most of the participants 128 (53%) were recruited from general practitioners clinics and 166 (69.5%) of them were dispensers. Mean (SD) knowledge score was 3.8 (2.3) with median of 4. MBBS prescribers had the highest knowledge score while the housekeepers had the lowest. Mean universal precautions use score was 2.7 +/- 2.1. Knowledge about mode of transmission and the work experience alone, significantly predicted universal precaution use in multiple linear regression model (adR2 = 0.093). CONCLUSION: Knowledge about mode of transmission of blood borne pathogens is very low. Use of universal precautions can improve with increase in knowledge

91.       Javadi AA, Mobasherizadeh S, Memarzadeh M, Mostafavizadeh K, Yazdani R, Tavakoli A. Evaluation of needle-stick injuries among health care workers in Isfahan province, Islamic Republic of Iran. Eastern Mediterranean Health Journal 2007; 13(1):209-210.
ABSTRACT: Sir, Health care workers (HCWs) are at-risk for infections with blood-borne pathogens such as human immunodeficiency virus, hepatitis b virus and hepatitis C virus from occupational blood-exposure through injuries with sharp instruments and needlesticks.  In the United States of America 86% of job-related bloodborn infections are caused by needle-stick injuries.  It has been estimated that as many as 40%-70% of all needlestick injuries are unreported.  Needle-stick injuries can be prevented, for example, by using safe needle devices and training HCWs to dispose of them properly; this protects the staff against bloodborn infections as well as reducing the high cost of follow-up.

92.       Karkar A. Hepatitis C in dialysis units: the Saudi experience. Hemodialysis International 2007; 11(3):354-367.
ABSTRACT: Hepatitis C virus (HCV) infection is a significant health problem, as it can lead to chronic active hepatitis, liver cirrhosis, and hepatic carcinoma. Patients undergoing hemodialysis treatment are at increased risk of contracting HCV and other viral infections. This is primarily due to their impaired cellular immunity, underlying diseases, and blood exposure for a prolonged period. Transmission of viral hepatitis, and in particular HCV in dialysis units, has been showing a progressive increase worldwide, ranging between 5% in some western countries and up to 70% in some developing countries. The annual rate of HCV seroconversion in Saudi Arabia is 7% to 9%, while its prevalence is variable between 15% and 80%. This prevalence remained at almost 50% in recent years, despite the further increase in number of patients with end-stage renal disease and the expansion of dialysis services. The most prevalent genotypes in Saudi Arabia are genotype 4 followed by genotypes 1a and 1b, whereas genotypes 2a/2b, 3, 5, and 6 are rare. Genotypes 1 and 4 were associated with different histological grades of liver disease. Mixed infections with more than one genotype were observed in some studies. Isolation of dialysis machines and infected patients, together with strict application of infection-control policies and procedures and continuous education and training of nursing staff, remain the cornerstone in prevention and control of the spread of HCV infection in dialysis units. Interferon (INF)-alpha or pegylated INF, alone or in combination with ribavirin, have shown great promise in the treatment of chronic HCV in dialysis patients

93.       Krikorian R, Lozach-Perlant A, Ferrier-Rembert A et al. Standardization of needlestick injury and evaluation of a novel virus-inhibiting protective glove. Journal of Hospital Infection 2007; 66(4):339-345.
ABSTRACT: Rubber surgical gloves worn as a barrier to prevent contamination from body fluids offer relative protection against contamination through direct percutaneous injuries involving needles, scalpel blades or bone fragments. To determine the main experimental parameters influencing the volume of blood transmitted by a hollow-bore needle (worst case scenario) during an accidental puncture, we designed an automatic puncture apparatus. Herpes simplex type 1 virus (HSV1), a model for enveloped viruses, was used as a 'marker' in an in-vitro gelatine model. Of the experimental parameters studied, the most critical influences were found to be needle diameter and puncture depth, whereas puncture speed, puncture angle and glove-stretching feature appeared to be less influential. A single glove reduced the volume of blood transferred by 52% compared with no glove, but double gloving offered no additional protection against hollow-bore needle punctures. Using 'standardized' puncture conditions, the virus-inhibiting surgical glove G-VIR((R)) elicited an 81% reduction in the amount of HSV1 transmitted as compared with single or double latex glove systems

94.       Krishnan P, Dick F, Murphy E. The impact of educational interventions on primary health care workers' knowledge of occupational exposure to blood or body fluids. Occupational Medicine (Oxford) 2007; 57(2):98-103.
ABSTRACT: AIM: To assess the impact of educational interventions on primary health care workers' knowledge of management of occupational exposure to blood or body fluids. METHODS: Cluster-randomized trial of educational interventions in two National Health Service board areas in Scotland. Medical and dental practices were randomized to four groups; Group A, a control group of practices where staff received no intervention, Group B practices where staff received a flow chart regarding the management of blood and body fluid exposures, Group C received an e-mail alert containing the flow chart and Group D practices received an oral presentation of information in the flow chart. Staff knowledge was assessed on one occasion, following the educational intervention, using an anonymous postal questionnaire. RESULTS: Two hundred and fifteen medical and dental practices were approached and 114 practices participated (response rate 53%). A total of 1120 individual questionnaires were returned. Face to face training was the most effective intervention with four of five outcome measures showing better than expected knowledge. Seventy-seven percent of staff identified themselves as at risk of exposure to blood and body fluids. Twenty-one percent of staff believed they were not at risk of exposure to blood-borne viruses although potentially exposed and 16% of exposed staff had not been immunized against hepatitis B. Of the 856 'at risk' staff, 48% had not received training regarding blood-borne viruses. CONCLUSIONS: We found greater knowledge regarding management of exposures to blood and body fluids following face to face training than other educational interventions. There is a need for education of at risk primary health care workers

95.       Kubitschke A, Bahr MJ, Aslan N et al. Induction of hepatitis C virus (HCV)-specific T cells by needle stick injury in the absence of HCV-viraemia. European Journal of Clinical Investigation 2007; 37(1):54-64.
ABSTRACT: BACKGROUND: The risk of hepatitis C virus (HCV) infection after occupational exposure is low with seroconversion rates between 0 and 5%. However, factors associated with natural resistance against HCV after needle stick injury are poorly defined. HCV-specific T-cell responses have been described in cross-sectional studies of exposed HCV-seronegative individuals. MATERIALS AND METHODS: In this study, we prospectively followed 10 healthcare professionals who experienced an injury with an HCV-contaminated needle. Blood samples were taken on the day or the day after the event and at different time points during follow-up for up to 32 months. HCV-specific T-cell responses were investigated directly ex vivo and in T-cell lines. RESULTS: None of the individuals became positive for HCV-RNA in serum tested with the highly sensitive transcription-mediated amplification (TMA)-assay or in peripheral blood mononuclear cells (PBMC). All of them remained anti-HCV negative throughout follow-up. At the time of injury, HCV-specific CD4+ T-cell responses were already detectable in two individuals and became detectable thereafter in three additional persons. Transient HCV-specific CD8+ T-cell responses developed in two HLA-A2 positive patients, which became negative until the most recent follow-up after 5 and 17 months, respectively. CONCLUSION: We demonstrate the development of HCV-specific T cells in HCV-exposed individuals after needle stick injury indicating subinfectious exposure to HCV. T-cell immunity against HCV may contribute to the low prevalence of HCV in medical healthcare professionals in Western countries

96.       Lamontagne F, Abiteboul D, Lolom I et al. Role of safety-engineered devices in preventing needlestick injuries in 32 French hospitals. Infection Control & Hospital Epidemiology 2007; 28(1):18-23.
ABSTRACT: Objectives. To evaluate safety-engineered devices (SEDs) with respect to their effectiveness in preventing needlestick injuries (NSIs) in healthcare settings and their importance among other preventive measures.Design. Multicenter prospective survey with a 1-year follow-up period during which all incident NSIs and their circumstances were reported. Data were prospectively collected during a 12-month period from April 1999 through March 2000. The procedures for which the risk of NSI was high were also reported 1 week per quarter to estimate procedure-specific NSI rates. Device types were documented. Because SEDs were not in use when a similar survey was conducted in 1990, their impact was also evaluated by comparing findings from the recent and previous surveys.Setting. A total of 102 medical units from 32 hospitals in France.Participants. A total of 1,506 nurses in medical or intensive care units.Results. A total of 110 NSIs occurring during at-risk procedures performed by nurses were documented. According to data from the 2000 survey, use of SEDs during phlebotomy procedures was associated with a 74% lower risk (P<.01). The mean NSI rate for all relevant nursing procedures was estimated to be 4.72 cases per 100,000 procedures, for a 75% decrease since 1990 (P<.01); however, the decrease in NSI rates varied considerably according to procedure type. Between 1990 and 2000, decreases in the NSI rates for each procedure were strongly correlated with increases in the frequency of SED use (r=0.88; P<.02).Conclusion. In this French hospital network, the use of SEDs was associated with a significantly lower NSI rate and was probably the most important preventive factor

97.       Leigh JP, Gillen M, Franks P et al. Costs of needlestick injuries and subsequent hepatitis and HIV infection. Curr Med Res Opin 2007; 23(9):2093-2105.
ABSTRACT: BACKGROUND: Physicians, nurses and other healthcare workers (HCWs) are at risk of bloodborne pathogens infection from needlestick injuries, but costs of needlesticks are little studied. METHODS: We used the cost-of-illness and incidence approaches. We used the perspective of the medical provider (medical costs) and the individual (lost productivity). Data on needlesticks, infections from hepatitis B and C (HBV, HCV) and human immune-deficiency (HIV) among HCWs, as well as data on per-unit costs were culled from research literature, Centers for Disease Control and Prevention reports, and Bureau of Labor Statistics reports. We also generated estimates based upon industry employment and scenarios for source-patients. These data and estimates were combined with assumptions to produce a model that generated base-case estimates as well as one-way and multi-way probabilistic sensitivity analyses. Future costs were discounted by 3%. RESULTS: We estimated 644,963 needlesticks in the healthcare industry for 2004 of which 49% generated costs. Medical costs were $107.3 million of which 96% resulted from testing and prophylaxis and 4% from treating long-term infections (34 persons with chronic HBV, 143 with chronic HCV, and 1 with HIV). Lost-work productivity generated $81.2 million, for which 59% involved testing and prophylaxis and 41% involved long-term infections. Combined medical and work productivity costs summed to $188.5 million. Multi-way sensitivity analysis suggested a range on combined costs from $100.7 million to $405.9 million. CONCLUSION: Detailed methodology was developed to estimate costs of needlesticks and subsequent infections for hospital-based and non-hospital-based health care workers. The combined medical and lost productivity costs comprised roughly 0.1% of all occupational injury and illness costs for all jobs in the economy. We did not account for lost home production or pain and suffering costs, however, nor did we estimate benefit/cost ratios of specific interventions to reduce needlesticks

98.       Lot F, Delarocque-Astagneau E, Thiers V et al. Hepatitis C virus transmission from a healthcare worker to a patient. Infection Control & Hospital Epidemiology 2007; 28(2):227-229.
ABSTRACT: We investigated the source of infection in a patient who developed acute hepatitis C virus infection after cardiothoracic surgery. A healthcare worker was found to be infected with hepatitis C virus, and molecular analysis indicated the strain was similar to that found in the patient. The exact mode of transmission was not identified; however, atopic eczema on the healthcare worker's hands may have contributed to the transmission

99.       Lynch P, Pittet D, Borg MA, Mehtar S. Infection control in countries with limited resources. Journal of Hospital Infection 2007; 65(S2):148-150.
ABSTRACT: Infection control (IC) in countries with limited resources potentially affects healthcare in all countries; infectious diseases have spread around the globe very efficiently but infection prevention has lagged behind.  Control of healthcare-associated infections (HAIs) is one of the great successes: it reduces illness andmortality and saves money for patients and hospitals.  Yet, today only 57 of 192 countries have national IC societies and there is still no global planning for managing this plague which is largely preventable, and which spawns a host of related problems including multidrug-resistant organisms and bloodborne infections among patients and healthcare workers (HCWs).  In fact, infection problems continue to be amplified in hosptials rather than reduced.  For example, the Severe Acute Respiratory Syndrome (SARS) began as a community-acquired, severe respiratory disease but ultimately, almost half of cases were due to hospital transmission.

100.    M'ikanatha NM, Imunya SG, Fisman DN, Julian KG. Sharp-device injuries and perceived risk of infection with bloodborne pathogens among healthcare workers in rural Kenya. Infection Control & Hospital Epidemiology 2007; 28(6):761-763.
ABSTRACT: To the Editor-Healthcare workers (HCWs) worldwide face the risk of occupational infection by bloodborne pathogens, including human immunodeficiency virus (HIV), hepatitis B virus (HBV), and hepatitis C virus (HCV). Guidelines  exist for preventing injuries from sharp devices (hereafter, sharps), as well as for postexposure evaluation and prophylaxis, but HCWs working in limited-resource settings may not have adequate access to these recommended safety measures. This is especially of concern where the prevalence of bloodborne pathogens in the patient population may be relatively high.

101.    Makary MA, Al-Attar A, Holzmueller CG et al. Needlestick injuries among surgeons in training. N Engl J Med 2007; 2007(26):2693-2699.
ABSTRACT: BACKGROUND: Surgeons in training are at high risk for needlestick injuries. The reporting of such injuries is a critical step in initiating early prophylaxis or treatment. METHODS: We surveyed surgeons in training at 17 medical centers about previous needlestick injuries. Survey items inquired about whether the most recent injury was reported to an employee health service or involved a "high-risk" patient (i.e., one with a history of infection with human immunodeficiency virus, hepatitis B or hepatitis C, or injection-drug use); we also asked about the perceived cause of the injury and the surrounding circumstances. RESULTS: The overall response rate was 95%. Of 699 respondents, 582 (83%) had had a needlestick injury during training; the mean number of needlestick injuries during residency increased according to the postgraduate year (PGY): PGY-1, 1.5 injuries; PGY-2, 3.7; PGY-3, 4.1; PGY-4, 5.3; and PGY-5, 7.7. By their final year of training, 99% of residents had had a needlestick injury; for 53%, the injury had involved a high-risk patient. Of the most recent injuries, 297 of 578 (51%) were not reported to an employee health service, and 15 of 91 of those involving high-risk patients (16%) were not reported. Lack of time was the most common reason given for not reporting such injuries among 126 of 297 respondents (42%). If someone other than the respondent knew about an unreported injury, that person was most frequently the attending physician (51%) and least frequently a "significant other" (13%). CONCLUSIONS: Needlestick injuries are common among surgeons in training and are often not reported. Improved prevention and reporting strategies are needed to increase occupational safety for surgical providers

102.    Manian FA, Ponzillo JJ. Compliance with routine use of gowns by healthcare workers (HCWs) and non-HCW visitors on entry into the rooms of patients under contact precautions. Infection Control & Hospital Epidemiology 2007; 28(3):337-340.
ABSTRACT: BACKGROUND: Modified contact precautions (MCP), defined as routine donning of isolation gowns (along with routine gloving) on entry into the rooms of patients under contact precautions, regardless of the likelihood of direct exposure to the patient or their immediate environment, were instituted at our medical center to reduce nosocomial transmission of common hospital pathogens. OBJECTIVES: To study compliance with MCP policy regarding routine gowning in intensive care units (ICUs) and general wards and to determine the relationship between gown and glove use in the care of patients under MCP in ICUs. DESIGN: Prospective observational study from February 20, 2004, through January 8, 2005, involving 2,110 persons (1,504 healthcare workers [HCWs] and 606 non-HCW visitors). SETTING: A 900-bed tertiary care teaching community hospital. RESULTS: Overall compliance with routine gown use was observed for 1,542 persons (73%), including 1,150 HCWs (76%) and 392 visitors (65%) (odds ratio [OR], 1.8 [95% confidence interval {CI}, 1.4-2.2]; P<.001). Visitors in the ICUs (186 [91%] of 204) were more likely than visitors in the general wards (202 [51%] of 398) to comply with gown use (OR, 10 [95% CI, 6.0-17.0]; P<.001). In logistic regression analysis, independent predictors of gown compliance among HCWs were female sex (OR, 2.3 [95% CI, 1.8-3.0]; P<.001) and ICU setting (OR, 2.2 [95% CI, 1.7-2.9]; P<.001). In the ICUs, gown use was highly predictive of glove use among HCWs (positive predictive value, 95%). CONCLUSION: Improvement in compliance with gown use at our medical center will require more-intensive educational efforts targeted at male HCWs and at HCWs and visitors on general wards. In the care of ICU patients under MCP, HCW compliance with gown use may be used as a proxy for their compliance with glove use

103.    Mantel C, Khamassi S, Baradei K, Nasri H, Mohsni E, Duclos P. Improved injection safety after targeted interventions in the Syrian Arab Republic. Tropical Medicine & International Health 2007; 12(3):422-430.
ABSTRACT: OBJECTIVES: Concerns about unsafe injection practices and possible infections with blood-borne pathogens in the Syrian Arab Republic motivated an assessment of the injection safety situation in the country in July 2001. In light of the recommendations from this assessment, the Ministry of Health of Syria, with the assistance of WHO, implemented a set of activities under the 'Focus Project', which aims to ensure immunization safety. The first phase of the project ran from May 2002 to February 2004, and consisted of the improved provision of injection safety equipment and supplies, the elaboration and wide distribution of national guidelines on injection safety and safe waste management, a behaviour change and communication campaign targeting the general public, and comprehensive training of healthcare workers. A follow-up survey was carried out in February 2004, 2 years after initiation of the project. METHODS: Two representative surveys were conducted using a standardized assessment tool. A cluster sampling strategy, with probability proportionate to the population size, led to the inclusion of 80 health facilities in eight districts in 2001 and of 120 health facilities in 12 districts in 2004. RESULTS: Injection practices had significantly improved 2 years after the start of the project. The 2001 study had pointed to a low, but non-negligible risk to patients (2% unsafe injections), coupled with a high risk to healthcare workers (61% reported needle-stick injuries in the last 12 months) and to the communities owing to unsafe waste disposal (sharps waste found outside 37% of health facilities, waste disposal considered unsafe in 48% of them). The 2004 survey showed that 90% of Syrian healthcare workers had received training in injection safety. All injections observed were given safely (difference to 2001 not significant), although some problems in preparation and reconstitution prevailed. The risk to healthcare workers was significantly reduced as only 14% of the staff reported needle-stick injuries (p < 0.001). The risk to the communities was notably decreased following improvements in sharps waste management (sharps were found in the surroundings of only 13% of health facilities, p < 0.001). CONCLUSIONS: The example of Syria shows that rapid improvement in injection safety is possible and that the necessary tools and methods to monitor and evaluate progress are at our disposal. Challenges remain in transferring this successful programme from the well-structured immunization programme to the more diverse curative health services

104.    Mattner F, Henke-Gendo C, Martens A et al. Risk of rabies infection and adverse effects of postexposure prophylaxis in healthcare workers and other patient contacts exposed to a rabies virus-infected lung transplant recipient. Infection Control & Hospital Epidemiology 2007; 28(5):513-518.
ABSTRACT: BACKGROUND: Rabies virus was inadvertently transmitted to a lung transplant recipient through donor lungs. The patient was given ventilatory assistance and cared for postoperatively for 6 weeks before a diagnosis of rabies virus infection was made. Postexposure prophylaxis (PEP) was offered to potentially exposed healthcare workers (HCWs). METHODS: Only HCWs classified as belonging to possible and/or proven contact groups (according to a standardized interview) received PEP. The risk of individual HCWs being exposed to rabies virus was reassessed on the basis of viral concentrations measured in the patient's excretions and body fluids. HCWs who were vaccinated as part of PEP were followed up prospectively according to a standardized procedure. RESULTS: Of 179 HCWs and other patient contacts, 132 met the eligibility criteria for PEP (118 [89.4%] with possible contact and 14 [10.6%] with proven contact with the patient's excretions and/or body fluids). One hundred thirty-one individuals started PEP, and 126 met the inclusion criteria for analysis. Of these, 48 (38%) developed at least 1 adverse effect (8 [6.3%] had fever, 37 [29.4%] had headache, 3 [2.4%] had lymphadenopathy, 17 [13.5%] had dizziness, and 6 [4.8%] had paresthesia). No HCW or other patient contact developed rabies or serious PEP-related adverse effects. Reassessment of the individual's risk of infection as a function of the viral concentration in the patient's excretions and/or body fluids (up to 5.12 x 10(7) copies/mL) revealed that 103 HCWs (78.0%) had contact with high-risk substances (89 [67.40%] had possible contact and 14 [10.7%] had proven contact). CONCLUSION: HCWs can be exposed to significant viral concentrations in excretions and/or body fluids from rabies virus-infected lung transplant recipients. Because widespread use of PEP entails the possibility of significant health problems for HCWs considered to be at risk of contracting rabies, applying a rational indication for PEP is crucial

105.    Mijai Grinberg. Doctor convicted of deliberately infecting patients with Hepatitis C. Haaretz 2007 Jul 10.
ABSTRACT: The Be'er Sheve Distrct Court on Tuesday convicted Dr. Sergel Puntos of 25 counts of causing grievous bodily h arm, intentionally spreading a disease, and posession and use of narcotics.

Puntos, who wored as an anesthesiologist at Be'er Sheva's Soroka Hospital, was accused of infecting 31 of his patients with hepatitis C by injecting them with sedatives using a syringe that he had used to inject himself with narcotics.

106.    Moro PL, Moore A, Balcacer P et al. Epidemiology of needlesticks and other sharps injuries and injection safety practices in the Dominican Republic. Am J Infect Control 2007; 35(8):552-559.
ABSTRACT: BACKGROUND: Contaminated sharps, such as needles, lancets, scalpels, broken glass, specimen tubes, and other instruments, can transmit bloodborne pathogens such as HIV, hepatitis B (HBV), and hepatitis C viruses (HCV). METHODS: Observation of facilities and injections and questionnaire-guided interviews were conducted in 2005 among health care workers (HCWs) in 2 public hospitals in Santo Domingo and 136 public immunization clinics (IC) in the Dominican Republic. Injection practices and sharps injuries (SIs) in health care facilities in the Dominican Republic were assessed in cross-sectional surveys to identify areas in which preventive efforts might be directed to make injection practices safer. RESULTS: Of the 304 hospital HCWs and 136 ICs HCWs interviewed, 98 (22.3%) reported > or =1 SIs during the previous 12 months. ICs had a lower incidence (13 per 100 per person-years [p-y]) of SIs than hospitals (65 per 100 p-y) (P < .0001). Unsafe needle recapping was observed in 98% of all injections observed at hospitals but in only 12% of injections at ICs (P < .0001). Sharps were observed improperly disposed in regular waste containers in 24 (92%) of 26 areas at which injections are prepared at the hospitals but in only 11 (8%) of 136 ICs (P < .0001). Training in injection safety was received by 4% of HCWs in hospitals but by 77% in ICs (P < .001). Of 425 HCWs, 247 (58%) were fully immunized against hepatitis B. There was a higher risk of SIs among staff dentists (adjusted relative risks [aRR], 5.9; 95% confidence interval [CI]: 2.8-12.6), resident physicians (aRR, 3.5; 95% CI: 1.8-6.9), and those who gave > or =11 therapeutic injections per day (aRR, 1.6; 95% CI: 1.1-2.4). CONCLUSION: Injection practices at ICs were safer than those found at public hospitals. Preventive strategies to lower SIs in public hospitals should include regular training of hospital staff to minimize needle recapping and improper disposal, among other interventions to reduce the dangers of needles

107.    Mullan F, Frehywot S. Non-physician clinicians in 47 sub-Saharan African countries. Lancet 2007; 370(9605):2158-2163.
ABSTRACT: Many countries have health-care providers who are not trained as physicians but who take on many of the diagnostic and clinical functions of medical doctors. We identified non-physician clinicians (NPCs) in 25 of 47 countries in sub-Saharan Africa, although their roles varied widely between countries. In nine countries, numbers of NPCs equalled or exceeded numbers of physicians. In general NPCs were trained with less cost than were physicians, and for only 3-4 years after secondary school. All NPCs did basic diagnosis and medical treatment, but some were trained in specialty activities such as caesarean section, ophthalmology, and anaesthesia. Many NPCs were recruited from rural and poor areas, and worked in these same regions. Low training costs, reduced training duration, and success in rural placements suggest that NPCs could have substantial roles in the scale-up of health workforces in sub-Saharan African countries, including for the planned expansion of HIV/AIDS prevention and treatment programmes

108.    Nagao Y, Baba H, Torii K et al. A long-term study of sharps injuries among health care workers in Japan. Am J Infect Control 2007; 35(6):407-411.
ABSTRACT: BACKGROUND: The risk of transmission of occupational blood-borne infection is a serious problem for health care workers (HCWs) in Japan. Although the Japanese version of Exposure Prevention Information Network (EPINet) was introduced in 1997, no published data in the clinical setting have been available yet. OBJECTIVE: To examine the epidemiology of occupational sharps injuries of HCWs in a university hospital using EPINet and to analyze the trends and changes in epidemiologic characteristics of needlestick injuries in a detailed situation. METHODS: The HCWs were requested to report sharps injury incidents to the Infection Control Nurse when the incidents occurred. Those who were involved in the incidents were required to personally complete an EPINET form. RESULTS: A total of 259 cases of sharps injuries occurred during the 7-year period. Registered nurses accounted for 72.2% of the cases, constituting the largest group of the HCWs. The incidents occurred most frequently in the hospital wards. Thirty-three cases (55.9%) of the injuries with syringe-needle units occurred "after use before disposal," whereas 34 cases (73.9%) of the injuries with suture needles occurred "during use of device." More than half of the injuries with a winged steel needle occurred despite the protective mechanism. DISCUSSION: There was no apparent difference in the characteristics of the subjects compared with other reports. The circumstances of the injuries varied with the kinds of instruments. This fact may provide useful information for planning measures to sharps injuries. CONCLUSIONS: With the problem of underreporting aside, a detailed study, such as ours, comprising by job category and by kind of instrument or the like would provide more useful and effective information in terms of sharps injury prevention

109.    O'Malley EM, Scott RD, Gayle J et al. Costs of management of occupational exposures to blood and body fluids. Infection Control & Hospital Epidemiology 2007; 28(7):774-782.
ABSTRACT: OBJECTIVE: To determine the cost of management of occupational exposures to blood and body fluids. DESIGN: A convenience sample of 4 healthcare facilities provided information on the cost of management of occupational exposures that varied in type, severity, and exposure source infection status. Detailed information was collected on time spent reporting, managing, and following up the exposures; salaries (including benefits) for representative staff who sustained and who managed exposures; and costs (not charges) for laboratory testing of exposure sources and exposed healthcare personnel, as well as any postexposure prophylaxis taken by the exposed personnel. Resources used were stratified by the phase of exposure management: exposure reporting, initial management, and follow-up. Data for 31 exposure scenarios were analyzed. Costs were given in 2003 US dollars. SETTING: The 4 facilities providing data were a 600-bed public hospital, a 244-bed Veterans Affairs medical center, a 437-bed rural tertiary care hospital, and a 3,500-bed healthcare system. RESULTS: The overall range of costs to manage reported exposures was $71-$4,838. Mean total costs varied greatly by the infection status of the source patient. The overall mean cost for exposures to human immunodeficiency virus (HIV)-infected source patients (n=19, including those coinfected with hepatitis B or C virus) was $2,456 (range, $907-$4,838), whereas the overall mean cost for exposures to source patients with unknown or negative infection status (n=8) was $376 (range, $71-$860). Lastly, the overall mean cost of management of reported exposures for source patients infected with hepatitis C virus (n=4) was $650 (range, $186-$856). CONCLUSIONS: Management of occupational exposures to blood and body fluids is costly; the best way to avoid these costs is by prevention of exposures

110.    Odusanya OO, Meurice FP, Hoet B. Nigerian medical students are at risk for hepatitis B infection. Transactions of the Royal Society of Tropical Medicine & Hygiene 2007; 101(5):465-468.
ABSTRACT: Medical students are exposed to blood and body fluids. This study was conducted to estimate the prevalence of hepatitis B virus (HBV) infection amongst medical students of the Lagos State University College of Medicine, Ikeja, Nigeria. Data were collected through a self-administered questionnaire and through blood analysis for hepatitis B surface antigen (HBsAg), hepatitis B 'e' antigen (HBeAg) as well as antibodies to the core (anti-HBc), surface (anti-HBs) and 'e' (anti-HBe) antigens. Three hundred and thirteen of 325 students (96%) participated. The mean age was 24.3+/-3.98 years; 231 (74%) were pre-clinical students and 82 (26%) were in the clinical years of study. Only 8 (2.6%) had received three doses of vaccination against HBV. Eighty-one (26%) tested positive for anti-HBc, 10 (3.2%) were positive for HBsAg and 56 (17.9%) had anti-HBs antibodies. A significant relationship was found between students who had a positive history of hepatitis B in the family and anti-HBc (P=0.03). Age was also significantly associated with HBsAg (P=0.012). Two hundred and twenty-five (72%) students were susceptible to the infection and required vaccination. Most students at this medical school are susceptible to HBV infection and should be vaccinated

111.    Pan A, Mondello P., Posfay-Barbe K. et al. Hand Hygiene and Glove Use Behavior in an Italian Hospital. Infection Control & Hospital Epidemiology 2007; 28(9):1099-1102.
ABSTRACT: In an Italian hospital, we observed that hand hygiene was performed in 638 (19.6%) of 3,253 opportunities, whereas gloves were worn in 538 (44.2%) 1,218 of opportunities. We observed an inverse correlation between the intensity of care and the rate of hand hygiene compliance (R2 = 0.057; P < .001), but no such association was observed for the rate of glove use compliance (R2 = 0.014; P = .078). Rates of compliance with hand hygiene and glove use recommendations follow different behavioral patterns.

112.    Phillips EK, Owusu-Ofori A, Jagger J. Bloodborne pathogen exposure risk among surgeons in sub-saharan Africa. Infection Control & Hospital Epidemiology 2007; 28(12):1334-1336.
ABSTRACT: To document the frequency and circumstances of bloodborne pathogen exposures among surgeons in sub-Saharan Africa, we surveyed surgeons attending the 2006 Pan-African Association of Surgeons conference. During the previous year, surgeons sustained a mean of 3.1 percutaneous injuries, which were typically caused by suture needles. They sustained a mean of 4.1 exposures to blood and body fluid, predominantly from blood splashes to the eyes. Fewer than half of the respondents reported completion of hepatitis B vaccination, and postexposure prophylaxis for human immunodeficiency virus was widely available. Surgeons reported using hands-free passing and blunt suture needles. Non-fluid-resistant cotton gowns and masks were the barrier garments worn most frequently

113.    Rabin R. When the Surgeon is Infected, How Safe is the Surgery? The New York Times 2007 Jul 3.
ABSTRACT: A few years ago, two Long Islanders with hepatitis C met in a support group and soon discovered they had something in common: both had become infected witht he virus after open-heart surgery - by the same surgeon.

Public health investigators, who were looking into one of the two cases, had not asked members of the patient's surgical team whether one of them might be infected.  Now they did.  Eventually they determined that the surgeon, Dr. Michael Hall, was infected and dthat he was the inadvertent source of both patients' infections -- and that of at least one other patient.

114.    Roden A. Needles less of sore point after safety syringes cut down injuries. Edinburgh Evening News 2007 Mar 14.
ABSTRACT: Needle injuries among Lothians health workers are down by a quarter after a landmark legal ruling forced hospitals to introduce safety syringes.

Thousands of health service staff are accidently priced by syringes every year, leaving them in fear of infection from HIV or hepatitis.

115.    Runner JC. Bacterial and viral contamination of reusable sharps containers in a community hospital setting. Am J Infect Control 2007; 35(8):527-530.
ABSTRACT: BACKGROUND: Proper disposal of sharps in the clinical setting is a key factor in infection control. Previous research studies suggest that reprocessed, reusable medical devices and infectious waste containers are potential sources of microorganisms capable of causing infection in immunocompromised patients. This pilot study was a single-center, prospective, hospital-based, microbiologic evaluation of reusable sharps disposal containers returned to the hospital from a reprocessing company. METHODS: A New England area, 130-bed community hospital performed the evaluation. Following delivery to the hospital's shipping/receiving area, 30 newly processed, reusable sharps disposal containers were swabbed for the presence of bacteria and viruses. RESULTS: Twenty-seven containers (90%) tested positive for bacteria, and 10% of the recovered isolates were gram-negative rods. Nine out of 30 (30%) cultures were positive for viruses: HIV (10%), hepatitis A (6.7%), hepatitis B (6.7%), and hepatitis C (13.3%), and several containers tested positive for multiple viruses and bacteria. CONCLUSION: Reusable sharps containers were returned to this medical facility with bacterial and viral contamination. Further testing is warranted to determine the scope of the problem and potential clinical implications

116.    Rupp ME, Sholtz LA, Jourdan DR et al. Outbreak of bloodstream infection temporally associated with the use of an intravascular needleless valve. Clinical Infectious Diseases 2007; 44(11):1408-1414.
ABSTRACT: BACKGROUND: Needleless intravascular catheter connector valves have been introduced into clinical practice to minimize the risk of needlestick injury. However, infection-control risks associated with these valves may be underappreciated. In March 2005, a dramatic increase in bloodstream infections was noted in multiple patient care units of a hospital in temporal association with the introduction of a needleless valve into use. METHODS: Surveillance for primary bloodstream infection was conducted using standard methods throughout the hospital. Blood culture contamination rates were monitored. Cultures were performed using samples obtained from intravascular catheter connector valves. RESULTS: The relative risk of bloodstream infection for the time period in which the suspect connector valve was in use, compared with baseline, was 2.79 (95% confidence interval, 2.27-3.43). In critical care units, the rate of primary bloodstream infection increased with the introduction of the valve from 3.87 infections per 1000 catheter-days to 10.64 infections per 1000 catheter-days (P<.001), and it decreased to 5.59 infections per 1000 catheter-days (P=.02) in the 6 months following removal of the device from use. Similarly, in inpatient nursing units, the rate of bloodstream infection increased from 3.47 infections per 1000 catheter-days to 7.3 infections per 1000 catheter-days (P=.02) following introduction of the device, and it decreased to 2.88 infections per 1000 catheter-days (P=.57) following removal of the device from use. Similar events occurred in the cooperative care units. The rate of blood culture contamination did not substantially change over the course of the study. Of 37 valves that were subjected to microbiological sample testing, 24.3% yielded microbes, predominantly coagulase-negative staphylococci. CONCLUSION: A significant association between primary bloodstream infection and a needleless connector valve was observed. Evaluation of needleless connector valves should include a thorough assessment of infection risks in prospective randomized trials prior to their introduction to the market

117.    Sacchi M, Daglio M, Feletti T, Lanave M, Candura SM, Strosselli M. [Accidents with risk of blood-borne infections in obstetricians: analysis of a hospital case records]. Med Lav 2007; 98(1):64-72.
ABSTRACT: BACKGROUND: Health care workers (HCW) are at high risk of accidental contact with biological fluids. In spite of extensive recom mendations concerning HCW accidents continue to be frequent and seem to be related to specific factors. OBJECTIVES: To evaluate the factors influencing risk of blood-borne infections in a particular category of HCW--obstetricians, and obtain information useful for prevention guidelines. METHODS: Data were obtained from the exposure registers of nursing and of the Emergency Ward staff where HCWfirst report after accidental contact with biological fluids. RESULTS: Accidents with risk of blood-borne diseases were more frequent in obstetricians with lower job seniority. They usually occurred between 8 a.m. and 4p. m., in the patient's room. The hands and face (particularly the eyes) were the body parts more often involved In almost half of the accidents, the worker was not wearing any personal protective device. Although some contacts were with infected blood, no seroconversion occurred. CONCLUSIONS: Obstetricians are at high risk of contact with biologicalfluids. Prevention requires a global strategy including the availability of protective and safety devices, as well as worker education, especially concerning the use of such devices, the application of the universal rules of prevention and the improvement of risk awareness. An adequate post-exposure management of accidents in also required

118.    Salamut W, Wilson JA. Needle-stick injuries from securing central lines. Anaesthesia 2007; 62(2):203.
ABSTRACT: We believe current practice for securing central lines is outdated and inherently unsafe. Central line insertion is a core skill for anaesthetists. During placement they are usually secured with a hand-held silk suture on a straight needle, a practice prone to promoting needle-stick injuries.

119.    Salgado CD, Chinnes L, Paczesny TH, Cantey JR. Increased rate of catheter-related bloodstream infection associated with use of a needleless mechanical valve device at a long-term acute care hospital. Infect Control Hosp Epidemiol 2007; 28(6):684-688.
ABSTRACT: OBJECTIVE: To determine whether introduction of a needleless mechanical valve device (NMVD) at a long-term acute care hospital was associated with an increased frequency of catheter-related bloodstream infection (BSI). DESIGN: For patients with a central venous catheter in place, the catheter-related BSI rate during the 24-month period before introduction of the NMVD, a period in which a needleless split-septum device (NSSD) was being used (hereafter, the NSSD period), was compared with the catheter-related BSI rate during the 24-month period after introduction of the NMVD (hereafter, the NMVD period). The microbiological characteristics of catheter-related BSIs during each period were also compared. Comparisons and calculations of relative risks (RRs) with 95% confidence intervals (CIs) were performed using chi (2) analysis. RESULTS: Eighty-six catheter-related BSIs (3.86 infections per 1,000 catheter-days) occurred during the study period. The rate of catheter-related BSI during the NMVD period was significantly higher than that during the NSSD period (5.95 vs 1.79 infections per 1,000 catheter-days; RR, 3.32 [95% CI, 2.88-3.83]; P<.001). A significantly greater percentage of catheter-related BSIs during the NMVD period were caused by gram-negative organisms, compared with the percentage recorded during the NSSD period (39.5% vs 8%; P=.007). Among catheter-related BSIs due to gram-positive organisms, the percentage caused by enterococci was significantly greater during the NMVD period, compared with the NSSD period (54.8% vs 13.6%; P=.004). The catheter-related BSI rate remained high during the NMVD period despite several educational sessions regarding proper use of the NMVD. CONCLUSIONS: An increased catheter-related BSI rate was temporally associated with use of a NMVD at the study hospital, despite several educational sessions regarding proper NMVD use. The current design of the NMVD may be unsafe for use in certain patient populations

120.    Scardino PT. A hazard surgeons need to address. Nat Clin Pract Urol 2007; 4(7):347.

121.    Schraag J. Sharps Safety Extends Beyond Hospital Walls. Infection Control Today 2007.
ABSTRACT: My son had a special friend in kindergarten whom neither of us will ever forget.  Little D was the sweetest boy -- so cute and full of life.  He was the baby of the three children in his family, and named after his daddy, Big D.

The reason I will always remember Little D isn't because the boys -- at the rip old age of 5 --got themselves locked out on the balcony at 4 a.m. during a sleepover.  It is because Little D, at the end of kidergarten, was told that his momma wouldn't make it to see him begin first grade.

122.    Shariati B, Shahidzadeh-Mahani A, Oveysi T, Akhlaghi H. Accidental exposure to blood in medical interns of Tehran University of Medical Sciences. J Occup Health 2007; 49(4):317-321.
ABSTRACT: Healthcare workers and medical students are at risk of exposure to blood-borne viruses such as HBV, HCV HIV, etc. Here we report the results of a survey of the frequency and causes of cutaneous blood exposure accidents (CBEA) among medical students. Anonymous questionnaires were randomly distributed to 200 interns in their second year of internship in hospitals affiliated to Tehran University of Medical Sciences. A definite exposure was defined as injury by a sharp object causing obvious bleeding, whereas a possible exposure was defined as subtle or superficial injury due to contact with a contaminated instrument or needle but without bleeding, or contamination of an existing wound with blood or other body fluids. One hundred eighty-four subjects (92% of the original sample) responded to the questionnaire. We recorded 121 definite exposures and 259 possible exposures over a mean time interval of 14 months. Needles were the most common objects (41% of exposure episodes) causing CBEAs, while phlebotomy and suturing were the hospital procedures that accounted for the highest percentage of exposure episodes (30 and 28 percent, respectively). Only a minority of students regularly observed basic safety measures (wearing gloves, not recapping used needles and proper disposal of sharp objects). Considering the high incidence of blood exposure in medical interns at Tehran University of Medical Sciences and the ensuing risk of blood-borne infections, the subjects are likely to develop such infections during their internship period

123.    Simard EP, Miller JT, George PA et al. Hepatitis B vaccination coverage levels among healthcare workers in the United States, 2002-2003. Infection Control & Hospital Epidemiology 2007; 28(7):783-790.
ABSTRACT: Background. Hepatitis B virus (HBV) infection is a well recognized risk for healthcare workers (HCWs), and routine vaccination of HCWs has been recommended since 1982. By 1995, the level of vaccination coverage among HCWs was only 67%.Objective. To obtain an accurate estimate of hepatitis B vaccination coverage levels among HCWs and to describe the hospital characteristics and hepatitis B vaccination policies associated with various coverage levels.Design. Cross-sectional survey.Methods. A representative sample of 425 of 6,116 American Hospital Association member hospitals was selected to participate, using probability-proportional-to-size methods during 2002-2003. The data collected included information regarding each hospital's hepatitis B vaccination policies. Vaccination coverage levels were estimated from a systematic sample of 25 HCWs from each hospital whose medical records were reviewed for demographic and vaccination data. The main outcome measure was hepatitis B vaccination coverage levels.Results. Among at-risk HCWs, 75% had received 3 or more doses of the hepatitis B vaccine, corresponding to an estimated 2.5 million vaccinated hospital-based HCWs. The coverage level was 81% among staff physicians and nurses. Compared with nurses, coverage was significantly lower among phlebotomists (71.1%) and nurses' aides and/or other patient care staff (70.9%; P<.05). Hepatitis B vaccination coverage was highest among white HCWs (79.5%) and lowest among black HCWs (67.6%; P<.05). Compared with HCWs who worked in hospitals that required vaccination only of HCWs with identified risk for exposure to blood or other potentially infectious material, hepatitis B vaccination coverage was significantly lower among HCWs who worked in hospitals that required vaccination of HCWs without identified risk for exposure to blood or other potentially infectious material (76.6% vs 62.4%; P<.05).Conclusions. In the United States, an estimated 75% of HCWs have been vaccinated against hepatitis B. Important differences in coverage levels exist among various demographic groups. Hospitals need to identify methods to improve hepatitis B vaccination coverage levels and should consider developing targeted vaccination programs directed at unvaccinated, at-risk HCWs who have frequent or potential exposure to blood or other potentially infectious material

124.    Slater K, Whitby M, McLaws ML. Prevention of needlestick injuries: the need for strategic marketing to address health care worker misperceptions. Am J Infect Control 2007; 35(8):560-562.
ABSTRACT: The occupational transmission of blood borne viruses (BBV) through needlestick injury (NSI) has been widely recognized over the past 20 years. While focused interventions have decreased the risk of NSI, little reduction has been reported in the prevalence of NSI due to hollow bore needles-an injury that poses the highest risk to health care workers (HCW).  We have previously reported2 the trends of NSI between 1990 and 1999 in the 800-bed university teaching Princess Alexandra Hospital (PAH), Brisbane, Australia. Despite an ongoing intensive education campaign, no significant fall in hollow bore injuries related to either syringes or winged butterfly needles occurred, although a reduction in recapping and downstream injuries was seen. We concluded that as education failed to significantly reduce the occurrence of these high-risk NSI, an engineering solution in the form of retractable devices may prove a cost-effective solution.

The two-year trial of retractable syringes commenced in October 2004. The trial was widely promoted and an extensive education program took place prior to implementation. The education focused not only on how to use the new devices, but also on the risks associated with various devices.

125.    Sofola OO, Folayan MO, Denloye OO, Okeigbemen SA. Occupational exposure to bloodborne pathogens and management of exposure incidents in Nigerian dental schools. J Dent Educ 2007; 71(6):832-837.
ABSTRACT: The goal of this study was to determine the frequency of occupational exposures to bloodborne pathogens amongst Nigerian clinical dental students, their HBV vaccination status, and reporting practices. A cross-sectional study of all clinical dental students in the four Nigerian dental schools was carried out by means of an anonymous self-administered questionnaire that asked questions on demography, number and type of exposure, management of the exposures, personal protection against cross infection, and the reporting of such exposures. One hundred and fifty-three students responded (response rate of 84.5 percent). Only thirty-three (37.9 percent) were fully vaccinated against HBV. Ninety (58.8 percent) of the students have had at least one occupational exposure. There was no significantly associated difference between sex, age, location of school, and exposure. Most of the exposures (44.4 percent) occurred in association with manual tooth cleaning. There was inadequate protection of the eyes. None of the exposures were formally reported. It is the responsibility of training institutions to ensure the safety of the students by mandatory HBV vaccination prior to exposure and adequate training in work safety. Written policies and procedures should be developed and made easily accessible to all workers to facilitate prompt reporting and management of all occupational exposures

126.    Talashek ML, Kaponda CP, Jere DL et al. Identifying what rural health workers in Malawi need to become HIV prevention leaders. J Assoc Nurses AIDS Care 2007; 18(4):41-50.
ABSTRACT: Health workers have high potential as HIV prevention leaders, but health system and individual barriers limit their impact. This descriptive qualitative study identified the HIV prevention needs of rural health workers to use as a basis for tailoring an HIV/AIDS risk-reduction intervention. Data included interviews with 9 health administrators, 22 focus groups with 200 health workers, and 12 observations of caregivers in two rural districts. Health system barriers identified included lack of essential supplies, staff shortages, overcrowded facilities, and lack of training. Individual barriers included hopelessness, stigmatizing attitudes, knowledge gaps, and risky personal behaviors. Health workers also expressed willingness to be HIV prevention leaders and role models. Most results agree with previous African studies. Personal risky behaviors and willingness to be HIV prevention leaders have not been previously reported. Results provide insights for developing effective interventions and health policies to address health workers' HIV prevention needs

127.    Tanne JH. Most US surgeons get needlestick injuries during training, few report them. BMJ 2007; 335(7 July 2007):10-11.
ABSTRACT: By the end of their five years of trainingin general surgery almost every US surgeons has received at least one needlestick injury.

128.    Tosti ME, Mariano A, Spada E et al. Incidence of parenterally transmitted acute viral hepatitis among healthcare workers in Italy. Infection Control & Hospital Epidemiology 2007; 28(5):629-632.
ABSTRACT: In Italy during 1995-2004, no significant difference was observed in the incidence rate of acute hepatitis B virus infection in the general population and in healthcare workers, with a downward trend noted in both groups. In contrast, the incidence rate of acute hepatitis C virus infection was significantly higher in healthcare workers than in the general population.

129.    Trinkoff AM, Le R, Geiger-Brown J, Lipscomb J. Work schedule, needle use, and needlestick injuries among registered nurses. Infection Control & Hospital Epidemiology 2007; 28(2):156-164.
ABSTRACT: Objective. To examine the association between working conditions and needlestick injury among registered nurses. We also describe needle use and needlestick injuries according to nursing position, workplace, and specialty.Design. Three-wave longitudinal survey conducted between November 2002 and April 2004.Setting and participants. A probability sample of 2,624 actively licensed registered nurses from 2 states in the United States. Follow-up rates for waves 2 and 3 were 85% and 86%, respectively. Respondents who had worked as a nurse during the past year (n=2,273) prior to wave 1 were included in this analysis.Results. Of the nurses, 15.6% reported a history of needlestick injury in the year before wave 1, and the cumulative incidence by wave 3 was 16.3%. The estimated number of needles used per day was significantly related to the odds of sustaining a needlestick injury. Hours worked per day, weekends worked per month, working other than day shifts, and working 13 or more hours per day at least once a week were each significantly associated with needlestick injuries. A factor combining these variables was significantly associated with needlestick injuries even after adjustment for job demands, although this association was somewhat explained by physical job demands.Conclusions. Despite advances in protecting workers from needlestick injuries, extended work schedules and their concomitant physical demands are still contributing to the occurrence of injuries and illnesses to nurses. Such working conditions, if modified, could lead to further reductions in needlestick injuries

130.    Valls V, Lozano MS, Yanez R et al. Use of safety devices and the prevention of percutaneous injuries among healthcare workers. Infect Control Hosp Epidemiol 2007; 28(12):1352-1360.
ABSTRACT: OBJECTIVE: To study the effectiveness of safety devices intended to prevent percutaneous injuries.Design. Quasi-experimental trial with before-and-after intervention evaluation. SETTING: A 350-bed general hospital that has had an ongoing educational program for the prevention of percutaneous injuries since January 2002. METHODS: In October 2005, we implemented a program for the use of engineered devices to prevent percutaneous injury in the emergency department and half of the hospital wards during the following procedures: intravascular catheterization, vacuum phlebotomy, blood-gas sampling, finger-stick blood sampling, and intramuscular and subcutaneous injections. The nurses in the wards that participated in the intervention received a 3-hour course on occupationally acquired bloodborne infections, and they had a 2-hour "hands-on" training session with the devices. We studied the percutaneous injury rate and the direct cost during the preintervention period (October 2004 through March 2005) and the intervention period (October 2005 through March 2006). RESULTS: We observed a 93% reduction in the relative risk of percutaneous injuries in areas where safety devices were used (14 vs 1 percutaneous injury). Specifically, rates decreased from 18.3 injuries (95% confidence interval [CI], 5.9-43.2 injuries) to 0 injuries per 100,000 patients in the emergency department (P=.002) and from 44.0 injuries (95% CI, 20.1-83.6 injuries) to 5.2 injuries (95% CI, 0.1-28.8 injuries) per 100,000 patient-days in hospital wards (P=.007). In the control wards of the hospital (ie, those where the intervention was not implemented), rates remained stable. The direct cost increase was 0.558 euros (US$0.753) per patient in the emergency department and 0.636 euros (US$0.858) per patient-day in the hospital wards. CONCLUSION: Proper use of engineered devices to prevent percutaneous injury is a highly effective measure to prevent these injuries among healthcare workers. However, education and training are the keys to achieving the greatest preventative effect

131.    Valls V, Lozano MS, Yanez R et al. Use of safety devices and the prevention of percutaneous injuries among healthcare workers. Infect Control Hosp Epidemiol 2007; 28(12):1352-1360.
ABSTRACT: Objective. To study the effectiveness of safety devices intended to prevent percutaneous injuries.Design. Quasi-experimental trial with before-and-after intervention evaluation.Setting. A 350-bed general hospital that has had an ongoing educational program for the prevention of percutaneous injuries since January 2002.Methods. In October 2005, we implemented a program for the use of engineered devices to prevent percutaneous injury in the emergency department and half of the hospital wards during the following procedures: intravascular catheterization, vacuum phlebotomy, blood-gas sampling, finger-stick blood sampling, and intramuscular and subcutaneous injections. The nurses in the wards that participated in the intervention received a 3-hour course on occupationally acquired bloodborne infections, and they had a 2-hour "hands-on" training session with the devices. We studied the percutaneous injury rate and the direct cost during the preintervention period (October 2004 through March 2005) and the intervention period (October 2005 through March 2006).Results. We observed a 93% reduction in the relative risk of percutaneous injuries in areas where safety devices were used (14 vs 1 percutaneous injury). Specifically, rates decreased from 18.3 injuries (95% confidence interval [CI], 5.9-43.2 injuries) to 0 injuries per 100,000 patients in the emergency department (P=.002) and from 44.0 injuries (95% CI, 20.1-83.6 injuries) to 5.2 injuries (95% CI, 0.1-28.8 injuries) per 100,000 patient-days in hospital wards (P=.007). In the control wards of the hospital (ie, those where the intervention was not implemented), rates remained stable. The direct cost increase was euro0.558 (US$0.753) per patient in the emergency department and euro0.636 (US$0.858) per patient-day in the hospital wards.Conclusion. Proper use of engineered devices to prevent percutaneous injury is a highly effective measure to prevent these injuries among healthcare workers. However, education and training are the keys to achieving the greatest preventative effect

132.    Venier AG, Vincent A, L'Heriteau F et al. Surveillance of occupational blood and body fluid exposures among French healthcare workers in 2004. Infection Control & Hospital Epidemiology 2007; 28(10):1196-1201.
ABSTRACT: Objective. To estimate the incidence rate of reported occupational blood and body fluid exposures among French healthcare workers (HCWs).Design. Prospective national follow-up of HCWs from January 1 to December 31, 2004.Setting. University hospitals, hospitals, clinics, local medical centers, and specialized psychiatric centers were included in the study on a voluntary basis.Participants. At participating medical centers, every reported blood and body fluid exposure was documented by the occupational practitioner in charge of the exposed HCW by use of an anonymous, standardized questionnaire.Results. A total of 375 medical centers (15% of French medical centers, accounting for 29% of hospital beds) reported 13,041 blood and body fluid exposures; of these, 9,396 (72.0%) were needlestick injuries. Blood and body fluid exposures were avoidable in 39.1% of cases (5,091 of 13,020), and 52.2% of percutaneous injuries (4,986 of 9,552) were avoidable (5.9% due to needle recapping). Of 10,656 percutaneous injuries, 22.6% occurred during an injection, 17.9% during blood sampling, and 16.6% during surgery. Of 2,065 splashes, 22.6% occurred during nursing activities, 19.1% during surgery, 14.1% during placement or removal of an intravenous line, and 12.0% during manipulation of a tracheotomy tube. The incidence rates of exposures were 8.9 per 100 hospital beds (95% confidence interval [CI], 8.7-9.0 exposures), 2.2 per 100 full-time-equivalent physicians (95% CI, 2.4-2.6 exposures), and 7.0 per 100 full-time-equivalent nurses (95% CI, 6.8-7.2 exposures). Human immunodeficiency virus serological status was unknown for 2,789 (21.4%) of 13,041 patients who were the source of the blood and body fluid exposures.Conclusion. National surveillance networks for blood and body fluid exposures help to better document their characteristics and risk factors and can enhance prevention at participating medical centers

133.    Wada K, Narai R, Sakata Y et al. Occupational exposure to blood or body fluids as a result of needlestick injuries and other sharp device injuries among medical residents in Japan. Infection Control & Hospital Epidemiology 2007; 28(4):507-509.
ABSTRACT: To the Editor-Medical residents are vulnerable to needlestick injuries and/or injuries from other sharp devices (hereafter referred to as needlestick and/or sharps injuries) because they lack experience and skill. In the United States, 71% of medical residents and medical students reported 1 or more needlestick and/or sharps injuries or other blood or body-fluid exposures every year.

134.    Wallis GC, Kim WY, Chaudhary BR, Henderson JJ. Perceptions of orthopaedic surgeons regarding hepatitis C viral transmission: a questionnaire survey. Ann R Coll Surg Engl 2007; 89(3):276-280.
ABSTRACT: INTRODUCTION: Occupationally acquired hepatitis C viral infection is an important issue in surgery since there are no known vaccines or effective prophylaxis. MATERIALS AND METHODS: An anonymous questionnaire survey was performed to determine the attitudes and perception of risks of occupational acquired hepatitis C viral transmission in orthopaedic surgeons. RESULTS: A total of 763 questionnaires were posted to orthopaedic surgeons with various subspecialty interests and 261 surgeons responded (34.2%). Of respondents, 117 (47%) had sustained sharps injuries in the previous 12 months. Only 82 surgeons (33%) always reported such injuries, although 208 (84%) expressed concerns of occupationally acquired hepatitis C viral transmission. Orthopaedic surgeons were mostly unaware of the true prevalence of hepatitis C in high-risk groups, such as intravenous drug abusers. CONCLUSIONS: Greater awareness of all aspects of hepatitis C infection and its risks to the practice of surgery is required. Further debate is necessary on the role of routine testing of surgeons and patients

135.    White RG, Ben SC, Kedhar A et al. Quantifying HIV-1 transmission due to contaminated injections. Proceedings of the National Academy of Sciences of the United States of America 2007; 104(23):9794-9799.
ABSTRACT: Assessments of the importance of different routes of HIV-1 (HIV) transmission are vital for prioritization of control efforts. Lack of consistent direct data and large uncertainty in the risk of HIV transmission from HIV-contaminated injections has made quantifying the proportion of transmission caused by contaminated injections in sub-Saharan Africa difficult and unavoidably subjective. Depending on the risk assumed, estimates have ranged from 2.5% to 30% or more. We present a method based on an age-structured transmission model that allows the relative contribution of HIV-contaminated injections, and other routes of HIV transmission, to be robustly estimated, both fully quantifying and substantially reducing the associated uncertainty. To do this, we adopt a Bayesian perspective, and show how prior beliefs regarding the safety of injections and the proportion of HIV incidence due to contaminated injections should, in many cases, be substantially modified in light of age-stratified incidence and injection data, resulting in improved (posterior) estimates. Applying the method to data from rural southwest Uganda, we show that the highest estimates of the proportion of incidence due to injections are reduced from 15.5% (95% credible interval) (0.7%, 44.9%) to 5.2% (0.5%, 17.0%) if random mixing is assumed, and from 14.6% (0.7%, 42.5%) to 11.8% (1.2%, 32.5%) under assortative mixing. Lower, and more widely accepted, estimates remain largely unchanged, between 1% and 3% (0.1-6.3%). Although important uncertainty remains, our analysis shows that in rural Uganda, contaminated injections are unlikely to account for a large proportion of HIV incidence. This result is likely to be generalizable to many other populations in sub-Saharan Africa

136.    Yang YH, Liou SH, Chen CJ et al. The effectiveness of a training program on reducing needlestick injuries/sharp object injuries among soon graduate vocational nursing school students in southern Taiwan. Journal of Occupational Health 2007; 49(5):424-429.
ABSTRACT: Needlestick/sharp injuries (NSIs/SIs) are a serious threat to medical/nursing students in hospital internships. Education for preventing NSIs/SIs is important for healthcare workers but is rarely conducted and evaluated among vocational school nursing students. We conducted an educational intervention for such students after their internship rotations before graduation. This program consisted of a lecture to the students after the internship training and a self-study brochure for them to study before their graduation. This study used the pre-test questionnaires completed by all students and the post-test questionnaires completed by 107 graduates after work experience as licensed nurses to assess the effectiveness of the intervention. After educational intervention, the incidence of NSIs/SIs decreased significantly from 50.5% pre-test to 25.2% post-test, and the report rate increased from 37.0% to 55.6%, respectively. In conclusion, this intervention significantly reduced the incidence of NSIs/SIs and increased the report rate of such events

137.    Yang YH, Liou SH, Chen CJ et al. The effectiveness of a training program on reducing needlestick injuries/sharp object injuries among soon graduate vocational nursing school students in southern Taiwan. J Occup Health 2007; 49(5):424-429.
ABSTRACT: Needlestick/sharp injuries (NSIs/SIs) are a serious threat to medical/nursing students in hospital internships. Education for preventing NSIs/SIs is important for healthcare workers but is rarely conducted and evaluated among vocational school nursing students. We conducted an educational intervention for such students after their internship rotations before graduation. This program consisted of a lecture to the students after the internship training and a self-study brochure for them to study before their graduation. This study used the pre-test questionnaires completed by all students and the post-test questionnaires completed by 107 graduates after work experience as licensed nurses to assess the effectiveness of the intervention. After educational intervention, the incidence of NSIs/SIs decreased significantly from 50.5% pre-test to 25.2% post-test, and the report rate increased from 37.0% to 55.6%, respectively. In conclusion, this intervention significantly reduced the incidence of NSIs/SIs and increased the report rate of such events

138.    Yasunaga H. Risk of authoritarianism: fibrinogen-transmitted hepatitis C in Japan. Lancet 2007; 370(9604):2063-2067.
ABSTRACT: In 1977, the US Food and Drug Administration revoked all licences for fibrinogen concentrate because of the risk for hepatitis infection and suspected lack of effectiveness. However, in Japan, fibrinogen concentrate was used routinely for treatment of obstetric bleeding until 1988. Even in 1997, academic texts by Japanese authorities in obstetrics still recommended that obstetricians use the product. An estimated 10 000 cases of hepatitis C infection are attributable to use of fibrinogen in Japan and are a result of authoritarianism that hindered effective policy changes. Scientists have a duty to refine repeatedly the quality of their evidence, and policymakers need to adjust existing policies continually to accord with the latest scientific evidence

139.    Yoshikawa T, Kidouchi K, Kimura S, Okubo T, Perry J, Jagger J. Needlestick injuries to the feet of Japanese healthcare workers: a culture-specific exposure risk. Infection Control & Hospital Epidemiology 2007; 28(2):215-218.
ABSTRACT: A comparison of needlestick injury surveillance data from Japan and the United States revealed a higher proportion of foot injuries to Japanese healthcare workers (HCWs), compared with US HCWs. This study investigates the underlying factors that contribute to this difference and proposes evidence-based prevention strategies to address the risk, including the use of safety-engineered needle devices, point-of-use disposal containers for sharp instruments and devices, and closed-toe footwear

140.    Zanni GR, Wick JY. Preventing needlestick injuries. Consult Pharm 2007; 22(5):400-6, 409.
ABSTRACT: Inadvertent puncture during use, disassembly, or disposal of needles or sharp devices (called collectively, "sharps") creates risk beyond a simple puncture. Sharps injury has always been a risk for health care workers, but emergence of certain blood-borne pathogens has intensified the need to act. Three- hepatitis B, hepatitis C, and HIV-are of utmost concern because they can cause significant morbidity or death. The incidence of sharps injury remains unacceptably high. Injury analysis at long-term care facilities and at the national level reveals several trends that can be used to shape policy and select interventions. Policy, practice, and training need to address new devices engineered to prevent sharps injuries, sharps disposal containers, and prophylaxis after percutaneous injury

141.    Adams D, Elliott TS. Impact of safety needle devices on occupationally acquired needlestick injuries: a four-year prospective study. J Hosp Infect 2006; 64(1):E pub.
ABSTRACT: A four-year prospective study was undertaken at the University Hospital Birmingham National Health Service Foundation Trust to evaluate the effect of the introduction of a range of safety hypodermic needle devices on the number of reported needlestick injuries (NSIs). Data on the number of reported NSIs for four clinical areas began in 2001. Following an enhanced sharps awareness strategy in 2002, the number of NSIs reduced from 16.9/100 000 devices used in 2001 to 13.9/100 000 devices (P=0.813). In 2003, when only standard training was provided, the number of NSIs increased to 20/100 000 devices. However, the subsequent introduction of three safety needle devices with concomitant training resulted in a significant reduction in the number of reported NSIs to 6/100 000 devices in 2004 (P=0.045). User satisfaction and acceptance of the safety needles was also very favourable. These results suggest that when safety needle devices are introduced into the clinical setting and appropriate training is given, a significant reduction in the number of occupationally acquired NSIs may ensue

142.    Al Habdan I, Corea JR, Sadat-Ali M. Double or single gloves: which is safer in pediatric orthopedic surgery. Journal of Pediatric Orthopedics 2006; 26(3):409-411.
ABSTRACT: BACKGROUND AND AIM:: Surgical gloves should form an efficient barrier between surgeons and patients to prevent cross infection. Single gloves (SGs) have long been reported unsafe, and usage of double gloves (DGs) is still not universal. No study has reported the usage of DGs in pediatric orthopedic operations. The aim of this study was to assess the efficacy of DGs versus SGs in prevention of body fluid contact between patients and surgeons during pediatric orthopedic surgery. METHODOLOGY:: After 150 pediatric orthopedic operations, DGs and SGs were collected and tested for perforations. Gloves were tested for size, site, and number of perforations among principal surgeons, assistant surgeons, and scrub nurses. Gloves were not changed during long surgical procedures and were changed only if perforations were identified and recorded. The DGs used were Maxitex Duplex, powder-free indicator gloves and the SGs were of Gammex-Ansell. One hundred unused gloves of each group were tested as controls. Medical records of the patients were reviewed for age, sex, type of operation, duration of operation, and any postoperative wound infection. The data were entered in database and analyzed using SPSS package. The data were compared between double and SGs using t test with a level of statistical significance at P less than 0.05. RESULTS:: Five hundred twenty-six DGs and 316 SGs were tested. Forty-three perforations were detected in DGs (8.1%). Outer gloves were breached in 7.8% and inner in 0.3% as compared with SGs in which 28 (8.7%) were perforated. In DGs, 4% had multiple perforations compared with 11.9% in SGs. There was a statistical significance (P < 0.001) when the perforations of inner gloves were compared with the SGs. None of the inner perforations were recognized during surgery, but the outer gloves of the DGs were recognized in 71% as compared with 9% in SGs (P < 0.001). The majority of perforations were seen in the nondominant hand in surgeons and assistants hands, whereas scrub nurses had 85% of perforations in the dominant hand. The index finger was the site of perforations in DGs (53.4%; SGs, 43%). The inner gloves were breached only when the outer glove was found to be perforated. The duration of surgery had a direct impact on the number of perforations. There were no perforations in DGs in less than 60 minutes as compared with 3 (10.7%) in SGs. Between 60 and 120 minutes, the perforations in the DGs were 11, and in SGs, 21. During the study period, 4 patients had surgical site infection. Three were superficial and one deep-seated infection. In 3 patients with infection, the gloves were found to be perforated, and 1 patient with infection had no perforations in the gloves. CONCLUSION:: Our study confirms that DGs are safer than SGs during pediatric orthopedic operations. In the event of nonavailability of DGs, SGs should be changed on an hourly basis during long procedures. Lastly, there exists a relationship between surgical site infection and glove perforations

143.    Al AS, Bawikar S, Duclos P. Safe injection practices in a primary health care setting in Oman. Eastern Mediterranean Health Journal 2006; 12:Suppl-16.
ABSTRACT: We conducted a national survey of injection practices in 78 government health facilities in Oman in 2001. Data were obtained by interview and observation. The overall standards were good and the stock of disposable equipment was adequate. Recapping of needles was only observed in 1 facility but in 28%, waste disposal boxes contained recapped needles and 17.9% reported needle-stick injuries in the past year. In 9% of the institutions, sharps were observed around the facility, in 12.8% unsupervised disposal containers were seen and in 11.5% unsafe storage of full boxes was observed. While disposal of the used waste was done away from the health facility, only 33.3% disposed of it by correct incineration

144.    Apisarnthanarak A, Babcock HM, Fraser VJ. Compliance with universal precautions among medical students in a tertiary care center in Thailand. Infection Control & Hospital Epidemiology 2006; 27(12):1409-1410.
ABSTRACT: To the Editor-Occupational exposure to bloodborne pathogens poses a serious threat to healthcare workers (HCWs). Transmission of at least 20 different pathogens by injuries due to sharp instruments and devices ("sharps") and needlesticks has been reported.  HCWs in developing countries face an even higher risk because of the elevated prevalence of hepatitis B virus (HBV), hepatitis C virus (HCV), and human immunodeficiency virus (HIV).  In addition, certain medical equipment used in developing countries, such as nonretracting finger-stick lancets and glass capillary tubes used to test for common tropical diseases, enhances the risk of transmission of bloodborne pathogens.  At Thammasart University Hospital (Pratumthani, Thailand), needlestick and sharps injuries occurred at the rate of 47 incidents per 1,000 HCWs in the year 2004. Most incidents occurred in the operating rooms, the emergency room, the medical service, the obstetrics and gynecology service, and the surgical service. Because medical students in Thailand are allowed to perform all surgical and invasive procedures, albeit under supervision because of their inexperience, they account for 47% of all such incidents reported (unpublished data, A.A.). To develop better needlestick injury prevention programs, we surveyed medical students to determine their knowledge of bloodborne pathogen transmission, their level of compliance with universal precautions, and their use of personal protective equipment.

145.    Armadans GL, Fernandez Cano MI, Albero A, I et al. [Safety-engineered devices to prevent percutaneous injuries: cost-effectiveness analysis on prevention of high-risk exposure]. [Spanish]. Gaceta Sanitaria 2006; 20(5):374-381.
ABSTRACT: OBJECTIVE: To assess the efficiency of the replacement of several medical devices by engineered sharp injury (SI) prevention devices (ESIPDs). METHODS: The cost-effectiveness ratios of the replacement of medical devices in use by ESIPDs were estimated: their purchasing costs and the direct costs of sharp injury care were taken into account; the number of SI avoidable by each ESIPD was estimated from the 252 occupational SI notified by healthcare workers at a 1,300 bed hospital from March 2002 to February 2003. The relationship between ESIPD additional costs and the number of high-risk SI was estimated (SI were classified as high-risk if they met two or more of the following criteria: moderately-deep or deep injury, injury with a device previously inserted in an artery or vein, or with a device exposed to blood). RESULTS: ESIPDs order according to cost-effectiveness ratio: safety needle for implanted ports (-2.65 euro/SI avoided), followed by syringes with protective shield (869.79 euro/SI), resheathable winged steel needles, needleless administration sets, and short catheters with protective encasement. ESIPDs order according to relationship between additional costs and number of high-risk sharp injuries avoided: safety needles for implanted ports, followed by winged steel needles, hypodermic syringes, short catheter and needleless administration sets. CONCLUSIONS: Savings in SI care outweigh additional costs of certain ESIPDs. Cost-effectiveness analysis is useful in assigning priorities; however the risks of SI by every device must be taken into account

146.    Ayas NT, Barger LK, Cade BE et al. Extended work duration and the risk of self-reported percutaneous injuries in interns. JAMA 2006; 296(9):1055-1062.
ABSTRACT: CONTEXT: In their first year of postgraduate training, interns commonly work shifts that are longer than 24 hours. Extended-duration work shifts are associated with increased risks of automobile crash, particularly during a commute from work. Interns may be at risk for other occupation-related injuries. OBJECTIVE: To assess the relationship between extended work duration and rates of percutaneous injuries in a diverse population of interns in the United States. DESIGN, SETTING, AND PARTICIPANTS: National prospective cohort study of 2737 of the estimated 18,447 interns in US postgraduate residency programs from July 2002 through May 2003. Each month, comprehensive Web-based surveys that asked about work schedules and the occurrence of percutaneous injuries in the previous month were sent to all participants. Case-crossover within-subjects analyses were performed. MAIN OUTCOME MEASURES: Comparisons of rates of percutaneous injuries during day work (6:30 am to 5:30 pm) after working overnight (extended work) vs day work that was not preceded by working overnight (nonextended work). We also compared injuries during the nighttime (11:30 pm to 7:30 am) vs the daytime (7:30 am to 3:30 pm). RESULTS: From a total of 17,003 monthly surveys, 498 percutaneous injuries were reported (0.029/intern-month). In 448 injuries, at least 1 contributing factor was reported. Lapse in concentration and fatigue were the 2 most commonly reported contributing factors (64% and 31% of injuries, respectively). Percutaneous injuries were more frequent during extended work compared with nonextended work (1.31/1000 opportunities vs 0.76/1000 opportunities, respectively; odds ratio [OR], 1.61; 95% confidence interval [CI], 1.46-1.78). Extended work injuries occurred after a mean of 29.1 consecutive work hours; nonextended work injuries occurred after a mean of 6.1 consecutive work hours. Injuries were more frequent during the nighttime than during the daytime (1.48/1000 opportunities vs 0.70/1000 opportunities, respectively; OR, 2.04; 95% CI, 1.98-2.11). CONCLUSION: Extended work duration and night work were associated with an increased risk of percutaneous injuries in this study population of physicians during their first year of clinical training

147.    Baggaley RF, Boily MC, White RG, Alary M. Risk of HIV-1 transmission for parenteral exposure and blood transfusion: a systematic review and meta-analysis. AIDS 2006; 20(6):805-812.
ABSTRACT: BACKGROUND: The role of iatrogenic transmission within the HIV/AIDS pandemic remains contentious. Estimates of the risk of HIV transmission from injections and blood transfusions are required to inform appropriate prevention policy. OBJECTIVES: Systematic review and meta-analysis of the literature on HIV-1 infectivity for parenteral transmission and blood transfusion. REVIEW METHODS: All identified studies with relevant transmission probability estimates up to May 2005 were included. STATISTICAL METHODS: When appropriate, summary estimates for accidental percutaneous and blood product exposures were derived. RESULTS: Infectivity estimates following a needlestick exposure ranged from 0.00 to 2.38% [weighted mean, 0.23%; 95% confidence interval (CI), 0.00-0.46%; n = 21]. Three estimates of infectivity per intravenous drug injection ranged from 0.63 to 2.4% (median, 0.8%); a summary estimate could not be calculated. The quality of the only estimate of infectivity per contaminated medical injection (1.9-6.9%) was assessed. Instead we propose a range of 0.24-0.65%. Infectivity estimates for confirmed contaminated blood transfusions range from 88.3 to 100.0% (weighted mean, 92.5%; 95% CI, 89.0-96.1%; n = 6). CONCLUSIONS: Infectivity estimates for infected blood transfusions are larger than for other modes of HIV transmission. Few studies on transmission risk per contaminated injection were found. However, transmission risk per needlestick injury, where needles are more likely to be rinsed or disinfected between recipients (especially for medical injections), may be representative of non-intravenous medical injections and lower than the risk from intravenous injections, which are likely to be deeper and to involve more fluids. Further work is needed to better estimate transmission probability related to contaminated injections and its likely contribution to overall HIV transmission

148.    Bakaeen F, Awad S, Albo D et al. Epidemiology of exposure to blood borne pathogens on a surgical service. Am J Surg 2006; 192(5):e18-e21.
ABSTRACT: BACKGROUND: The goal of this study was to analyze the type and mechanism of blood exposure injuries on the surgical service in order to develop appropriate preventative strategies. METHODS: A retrospective review of all exposure injuries affecting members of the operative care line at a single teaching institution between December 2002 and December 2005 was performed. RESULTS: Of 98 exposure injuries on the surgical service, only 17 (17%) were inflicted by hollow-bore needles. Seventy-four (76%) of these reported injuries occurred in the operating room (OR) and 24 (24%) occurred in other clinical areas. Sharps injuries accounted for 69 (93%) of OR injuries and were inflicted by suture needles (n = 37, 50%), hollow-bore needles (n = 7, 9%), and sharp instruments (n = 25, 34%). Mucocutaneous contamination accounted for 5 (7%) of the OR exposures. Professionals most frequently injured were residents (n = 43, 44%), followed by nurses (n = 28, 29%), students (n = 17, 17%) and other healthcare workers (n = 10, 10%). CONCLUSIONS: Blood exposure prevention strategies should be directed at safety within the surgical field and focused beyond hollow-bore needle stick injuries to include education, mentoring, and competency training

149.    Bellissimo-Rodrigues WT, Bellissimo-Rodrigues F, Machado AA. Occupational exposure to biological fluids among a cohort of Brazilian dentists. Int Dent J 2006; 56(6):332-337.
ABSTRACT: OBJECTIVE: To evaluate the epidemiology of percutaneous occupational exposure to biologic fluids and the level of compliance with some recommendations contained in the 'Standard Precautions' among dentists. SETTING: Sertaozinho city, Brazil. PARTICIPANTS: All dentists who were currently working in public or private offices in the study city, and who agreed to participate, resulting in a study population of 135 dentists. METHODS: All participants were personally interviewed from August 2001 to April 2002. RESULTS: Of the dentists interviewed, 31.1% reported accidents, with a mean incidence of 2.02 accidents/professional/year; 90.0% recapped needles after using them, while 8.1% re-used gloves. Injuries involved the hands and the item most frequently mentioned was a needle. Inadequate procedures were observed regarding the disposal of sharp devices and hand hygiene. CONCLUSIONS: Dentists evaluated do not properly obey the norms for infection control during their clinical activities, with consequent risks for their own and their patients' health. Measures must be adopted by class institutions, universities, public agencies, and especially by these professionals in order to reverse this situation

150.    Bi P, Tully PJ, Pearce S, Hiller JE. Occupational blood and body fluid exposure in an Australian teaching hospital. Epidemiol Infect 2006; 134(3):465-471.
ABSTRACT: To examine work-related blood and body fluid exposure (BBFE) among health-care workers (HCWs), to explore potential risk factors and to provide policy suggestions, a 6-year retrospective study of all reported BBFE among HCWs (1998-2003) was conducted in a 430-bed teaching hospital in Australia. Results showed that BBFE reporting was consistent throughout the study period, with medical staff experiencing the highest rate of sharps injury (10.4%). Hollow-bore needles were implicated in 51.7% of all percutaneous injuries. Most incidents occurred during sharps use (40.4%) or after use but before disposal (27.1%). Nursing staff experienced 68.5% of reported mucocutaneous exposure. Many such exposures occurred in the absence of any protective attire (61.1%). This study indicated that emphasis on work practice, attire, disposal systems and education strategies, as well as the use of safety sharps should be employed to reduce work-related injuries among HCWs in Australia

151.    Bilski B, Kostiukow A, Ptak D. [Risk bloodborne infections in health care workers]. Med Pr 2006; 57(4):375-379.
ABSTRACT: The paper presents current data on epidemiology and risk factors responsible for incidents leading to blood-borne infections among health care workers. In many countries, the number of this type of incidents has markedly decreased, whereas in Poland blood-borne infections are still a serious problem. Unfortunately, the circumstances, in which such incidences happen, are frequently caused by oversight and typical mistakes. The problem also lies in that not all cases are regularly reported. Therefore, it is essential to draw special attention to under- and post-graduate programs covering all medical professions, in which the problem of occupational and hospital infections should be an obligatory element of training

152.    Bilski B, Kostiukow A, Ptak D. [Risk bloodborne infections in health care workers]. [Polish]. Medycyna Pracy 2006; 57(4):375-379.
ABSTRACT: The paper presents current data on epidemiology and risk factors responsible for incidents leading to blood-borne infections among health care workers. In many countries, the number of this type of incidents has markedly decreased, whereas in Poland blood-borne infections are still a serious problem. Unfortunately, the circumstances, in which such incidences happen, are frequently caused by oversight and typical mistakes. The problem also lies in that not all cases are regularly reported. Therefore, it is essential to draw special attention to under- and post-graduate programs covering all medical professions, in which the problem of occupational and hospital infections should be an obligatory element of training

153.    Bouchard F. Les dispositifs sécuritaires pour réduire les expositions au sang. Objectif Prévention 2006; 29(4):22-25.
ABSTRACT: Le risque d'EAS est très présent dans les milieux de soins et difficile à éliminer totalement.  Le moyen le plus efficace pour éliminer à la source ou pour contrôler le risque d'EAS consiste à utiliser les DS.  Des études démontrent que l'utilisation de DS, lorsqu'ils font partie d'un programme global de réduction des EAS, peut être très efficace.  Des taux d'efficacité allant jusqu'à 88% ont été mesurés.

154.    Calfee DP. Prevention and management of occupational exposures to human immunodeficiency virus (HIV). Mt Sinai J Med 2006; 73(6):852-856.
ABSTRACT: Occupational exposure to blood and other potentially infectious body fluids places health care workers at risk for acquisition of bloodborne pathogens, including the human immunodeficiency virus (HIV). Utilizing appropriate techniques, personal protective equipment, and safer "sharp" technology can minimize the risk of these exposures. When exposure does occur, immediate evaluation and initiation of post-exposure prophylaxis, when indicated. can substantially reduce the risk of transmission of HIV. In this article, the basic concepts of exposure prevention and management are reviewed

155.    Chandler RE, Lee LE, Townes JM, Taplitz RA. Transmission of group A Streptococcus limited to healthcare workers with exposure in the operating room. Infection Control & Hospital Epidemiology 2006; 27(11):1159-1163.
ABSTRACT: BACKGROUND: Nosocomial transmission of group A Streptococcus (GAS) has been well described. A recent report of an outbreak investigation suggested that transmission can be extensive and that standard infection control measures may not be adequate to prevent transmission from patients with severe, invasive disease to healthcare workers (HCWs). OBJECTIVE: A case of pharyngitis in an HCW caring for a patient with GAS pharyngitis and necrotizing fasciitis prompted an investigation of the extent and risk factors for nosocomial transmission of GAS. SETTING: A 509-bed, tertiary care center in Portland, Oregon with 631,100 patient visits (hospital and clinic) and 11,500 employees in the year 2003. METHODS: HCWs with exposure to the index patient ("contacts") were identified for streptococcal screening and culture and completion of a questionnaire regarding the location and duration of exposure, use of personal protective equipment, and symptoms of GAS infection. RESULTS: We identified 103 contacts of the index patient; 89 (86%) submitted oropharyngeal swabs for screening and culture. Only 3 (3.4%) of contacts had a culture that yielded GAS; emm typing results and pulsed-field gel electrophoresis patterns of GAS isolates from 2 HCWs were identical to those for the isolate from the index patient. Both HCWs were symptomatic, with febrile pharyngitis and reported prolonged contact with the open wound of the patient in the operating room. CONCLUSIONS: In this investigation, nosocomial transmission was not extensive, and standard precautions provided adequate protection for the majority of HCWs. Transmission was restricted to individuals with prolonged intraoperative exposure to open wounds. As a result, infection control policy for individuals was modified only for HCWs with exposure to GAS in the operating room

156.    Coleman C. Jury Backs HIV-Positive Cleaning Woman. New York Daily News 2006 May 5.
ABSTRACT: A cleaning woman who became HIV-positive after pricking her finger on dirty needles while working at an upscale Manhattan medical center was awarded $4 million by a Bronx jury.

The woman, whose name was withheld by the court, sued the Madison Medical Cener, which treats AIDS patients.  According to her attorney, George Pfluger, the woman pricked with a needle on Dec. 11, 1998, and again on Feb. 1, 1999, while emptying the trash.

Madison Medical Center officials didn't respond to calls for comment.  During the trail, the center's lawyers said the victim knew the dangers of cleaning the office and should have been more careful.  The defense has moved to set aside the verdict.

Pfluger said this was one of the saddest cases he's ever experienced.

"My client is pleased with the verdict, but she is severely depressed," he said.  "She doesn't have full-blown AIDS, but she's living with a deadly, ticking time bomb."

157.    Cullen BL, Genasi F, Symington I et al. Potential for reported needlestick injury prevention among healthcare workers through safety device usage and improvement of guideline adherence: expert panel assessment. J Hosp Infect 2006; 63(4):445-451.
ABSTRACT: A prospective survey was conducted over six months in order to estimate the proportion of reported occupational needlestick injuries sustained by National Health Service (NHS) Scotland staff that could have been prevented through either safety device introduction, improved guideline adherence, guideline revision or a combination of these. This survey involved the administration of a standard proforma to healthcare workers followed by an expert panel assessment. All acute and primary care NHS Scotland trusts, the Scottish Ambulance Service and the Scottish National Blood Transfusion Service were included. Proforma and expert panel assessment data were available for 64% of injuries (952/1497) reported by healthcare staff. These injuries were all percutaneous. The expert panel concluded that: 56% of all injuries and 80% of venepuncture/injection administration injuries would probably/definitely have been prevented through safety device usage, 52% of all injuries and 56% of venepuncture/injection administration injuries would probably/definitely have been prevented through guideline adherence and 72% of all injuries and 88% of venepuncture/injection administration injuries would probably/definitely have been prevented through either intervention. Multi-factorial analysis indicated that injuries sustained through venepuncture/injection administration were significantly more likely to be prevented through safety device usage [adjusted odds ratio (OR) 5.09, 95% confidence intervals (CI) 3.11-8.31 and adjusted OR 2.70, 95% CI 1.64-4.45, respectively], and significantly less likely to be prevented through guideline adherence (adjusted OR 0.26, 95% CI 0.11-0.60 and adjusted OR 0.31, 95% CI 0.12-0.78, respectively). Injuries sustained after completing procedures were significantly more likely to be prevented through safety device usage and guideline adherence. The study's findings support the need for improvements to staff's adherence to needlestick injury guidelines and appropriate implementation of safety devices for venepuncture and injection administration

158.    Dannetun E, Tegnell A, Torner A, Giesecke J. Coverage of hepatitis B vaccination in Swedish healthcare workers. J Hosp Infect 2006; 63(2):201-204.
ABSTRACT: The aim of this study was to assess how well the guidelines on vaccination against hepatitis B had been implemented among healthcare workers (HCWs) at risk for blood exposure. A point-prevalence survey was conducted in six departments of a university hospital in Sweden: the emergency room, intensive care unit, postoperative unit, surgical theatre, department of anaesthesiology and the laboratory for blood chemistry. All HCWs who worked in these departments during the 24h of the survey were asked to complete a questionnaire. In total, 369 questionnaires were analysed. Seventy-nine percent (293/369) of HCWs had received at least one dose of vaccine, but only 40% (147/369) reported that they were fully vaccinated and 21% (76/369) had not been vaccinated at all. The majority of unvaccinated HCWs (72/76, 95%) stated that they would accept vaccination if offered. The main barrier to better compliance with the guidelines is not lack of acceptance among the employees but the failure of the employer to ensure that policies are implemented

159.    de Souza RA, Namen FM, Galan J, Jr., Vieira C, Sedano HO. Infection control measures among senior dental students in Rio de Janeiro State, Brazil. Journal of Public Health Dentistry 2006; 66(4):282-284.
ABSTRACT: OBJECTIVE: The aim of this study was to verify the practices and attitudes of senior dental students about infection control procedures. METHODS: A cross-sectional survey was performed during the 1st semester of 2003. Open- and close-ended questions were given to 196 students in 6 universities. RESULTS: Overall, 90.8% of students had been vaccinated for hepatitis B. Only 25.0% have been assessed for anti-HBs. A total of 99.5% students reported always using gloves for all procedures. Eye protection were always used by 84.2% of students, and all the students used face masks for all procedures. Caps or hair covers were used by 92.3% of students and 87.8% reported no objection to treating patients with infectious diseases. Among instructors, the students observed that 60.2% of them did not use gloves for all procedures, 43.4% of those didn't change gloves between patients. CONCLUSIONS: These results address the need for an improved quality assurance, in order for the students and faculty to improve their practices and attitudes on infection control measures

160.    de Waal N, Rabie H, Bester R, Cotton MF. Mass needle stick injury in children from the Western cape. J Trop Pediatr 2006; 52(3):192-196.
ABSTRACT: Illegal dumping of contaminated medical waste occurs commonly in South Africa. There is little information on the management and outcome of the children exposed to and injured by medical waste. On 15 September 1999, 54 children where involved in a mass exposure incident. 44 presented the same evening and 10 following day. Used needles and syringes were discarded on their soccer field. Children gave one another injections and played darts with the discarded needles. Parents were counselled and blood was drawn for HIV and Hepatitis B virus (HBV) serology. All were given HBV vaccination (HBVV). Stat doses of zidovudine (ZDV) and lamivudine (LMV) were given to all with visible wounds or history of percutaneous injury. Younger children were given prophylaxis as we considered their histories unreliable. Further visits were conducted at the community clinic for patient convenience. Children were reviewed at weeks 1 and 3 for drug adherence and side effects. At week 4, the second HBVV was given. At 3 months and 6 months HIV and HBV serology were repeated. 18/44 (40 per cent) had entry wounds. 44/54 (81 per cent) were given antiretroviral treatment (ART). Initial screening for HIV was negative in all, 6 had antibodies to HBV surface antigen, and 2 were HBV surface antigen positive. At week 1 all patients on ART were seen but at week 3 only 30 (55 per cent) attended. 41 (75 per cent) attended at 4 weeks, 8 non-attendees being located by primary healthcare workers. At 3 months, none of the 35 (64 per cent) children had seroconverted for either virus. 44 (81 per cent) attended at 6 months and all serology was negative. All were also Hepatitis C negative. The exposure incident sensitized the community to HIV. Follow up of patients after mass exposure is difficult and time-consuming. Adherence to ART was poor and should be carefully monitored. ZDV was probably adequate for this incident. In a non-mobile community a 3 month visit unnecessary

161.    de OT, Pybus OG, Rambaut A et al. Molecular epidemiology: HIV-1 and HCV sequences from Libyan outbreak. Nature 2006; 444(7121):836-837.
ABSTRACT: In 1998, outbreaks of human immunodeficiency virus type 1 (HIV-1) and hepatitis C virus (HCV) infection were reported in children attending Al-Fateh Hospital in Benghazi, Libya. Here we use molecular phylogenetic techniques to analyse new virus sequences from these outbreaks. We find that the HIV-1 and HCV strains were already circulating and prevalent in this hospital and its environs before the arrival in March 1998 of the foreign medical staff (five Bulgarian nurses and a Palestinian doctor) who stand accused of transmitting the HIV strain to the children

162.    Deisenhammer S, Radon K, Nowak D, Reichert J. Needlestick injuries during medical training. J Hosp Infect 2006; 63(3):263-267.
ABSTRACT: Medical students are at risk of acquiring infections caused by needlestick injuries, although it is unknown when needlestick injuries are most likely to occur during medical training. The aim of this study was to define high-risk periods over the course of medical training. A cross-sectional study was conducted among medical students in the first, third, fourth and fifth years of training at two medical schools in Munich. Overall, 1317 (85%) students returned a questionnaire on demographic data, vaccination status against hepatitis B, lifetime prevalence of needlestick injuries, level of knowledge about measures after such accidents, and transmission risks. Lifetime prevalence of needlestick injuries was 23%, ranging from 12% in first year students to 41% in fourth year students. These accidents happened most commonly during medical internships, especially during blood-taking practices; an activity that usually starts during the third year of training. The frequency of respondents not vaccinated against hepatitis B also varied between first (21%) and fourth (6.6%) year students. Needlestick injuries occur frequently and early on in medical training. In order to decrease the risk of preventable infections, complete coverage of vaccination against hepatitis B should be achieved early in medical training

163.    Deuchert E, Brody S. The role of health care in the spread of HIV/AIDS in Africa: evidence from Kenya. International Journal of STD & AIDS 2006; 17(11):749-752.
ABSTRACT: It is commonly asserted that the sub-Saharan African HIV/AIDS epidemic is predominantly due to heterosexual transmission. However, recent re-examination of the available evidence strongly suggests that unsafe health care is the more likely vector. The present report adds to the evidence for health-care transmission by showing that Kenyan women who received prophylactic tetanus toxoid injections during pregnancy are 1.89 times (95% confidence interval [CI]:1.03-3.47) more likely to be HIV-1 seropositive than women who did not receive this vaccination. In contrast, recent sexual behaviour (condom use, number of partners) was not related to HIV status. The findings are unconfounded by reverse causality (all injections were purely prophylactic rather than for treatment of any HIV-related illnesses, and none of the women reported knowing that she was HIV seropositive). Focus on a specific injection may have improved participant recall. The results are consistent with health care being a very important vector for HIV in sub-Saharan Africa. It is recommended that there be a reallocation of resources to address healthcare transmission of HIV/AIDS

164.    Elder A, Paterson C. Sharps injuries in UK health care: a review of injury rates, viral transmission and potential efficacy of safety devices. Occup Med (Lond) 2006; 56(8):566-574.
ABSTRACT: AIMS: To review the literature on sharps injuries and occupational bloodborne virus transmission in health care in the UK and the worldwide evidence for injury prevention of sharps safety devices. METHODS: Literature review by online database and Internet resource search. RESULTS: Twenty-four relevant publications were identified regarding UK reported sharps injury rates. UK studies showed as much as a 10-fold difference between injuries reported through standard reporting systems (0.78-5.15 per 100 person-years) and rates estimated from retrospective questionnaires of clinical populations (30-284 per 100 person-years). National surveillance data from England, Wales and Northern Ireland gives a rate of 1.43 known hepatitis C virus or human immunodeficiency virus (HIV) transmissions to health care workers per annum. When extrapolated, this suggests an approximate rate of 0.009 such viral transmissions per 1000 hospital beds per annum. Risk of infection from sources with no risk factors is extremely small (less than one in one million for HIV transmission based on Scottish data). Thirty-one studies on the efficacy of sharps safety devices showed evidence of a reduction in injuries, with the greatest reductions achieved by blunt suture needles and safety cannulae. CONCLUSIONS: Although injuries remain common, confirmed viral transmission in the UK has been relatively rare. The degree of under-reporting of sharps injuries may be as much as 10-fold. Safety-engineered devices are likely to be effective at injury reduction

165.    Erdem Y, Talas MS. Blunt and penetrating object injuries in housekeepers working in a Turkish University Hospital. Am J Infect Control 2006; 34(4):208-214.
ABSTRACT: BACKGROUND: Hospitals have been described as hazardous work environments with an increase in job-related injuries. This situation creates great risks and hazards for housekeepers while carrying out their job. METHODS: This descriptive study was performed on 402 housekeepers working in patient-care services in Turkey. The data of this study were collected using a questionnaire form. This form included 26 questions about general features of housekeepers and working units, blunt and penetrating object injuries in the past 3 months and hepatitis B virus immunization. RESULTS: The majority of housekeepers (71.1%) are men, (54%) are graduates of primary school or are illiterate, and (73.6%) are married. Their mean age is 31.5 years; the mean length of employment is 3.2 years. Sixty-two point nine percent of them are working in medical/surgical units, 88.8% of them are working in routine cleaning, and 29.1% of them have been injured with various blunt and penetrating objects while working in hospital in the past 3 months. Only 26.6% of the housekeepers have been administered the hepatitis B vaccination. CONCLUSION: This study showed a high frequency of blunt and penetrating object injuries in housekeepers. Therefore, more efforts are necessary to increase compliance with vaccination in housekeepers

166.    Gabriel J. Needle stick injuries: How can we minimise our risk? J Vasc Access 2006; 7(1):3-6.
ABSTRACT: In the United Kingdom (UK) there is inequity in health care workers access to safer sharps and needle free systems. The availability of safer sharps and needle free systems is dependent on the budget manager authorising the purchase of these devices within individual hospitals. This can mean that within the same organisation one de-partment can be using safer sharps and needle free systems, while another department is denied access to such equipment. This is partly due to competing priorities for scarce health care resources, which is becoming more acute, and lack of national guidance to employers to provide such safety equipment for their employees. At the current time the UK does not have a mandatory reporting system for sharps injuries, so the true extend of the problem is not fully understood

167.    Ganczak M, Milona M, Szych Z. Nurses and occupational exposures to bloodborne viruses in Poland. Infection Control & Hospital Epidemiology 2006; 27(2):175-180.
ABSTRACT: STUDY OBJECTIVE: To record descriptions of occupational exposures to blood, determine factors predictive of exposure, and identify interventions that might reduce the frequency of exposure. DESIGN: An analytic, cross-sectional survey. STUDY POPULATION: A total of 601 nurses from surgical wards, operating rooms, and emergency departments. STUDY INSTRUMENT: An anonymous questionnaire developed by the authors on the basis of previously published guidelines was distributed between January and March 2003. SAMPLING: Random, with 18 hospitals selected from 2 urban and rural locations. RESULTS: Almost half of respondents reported having had at least 1 puncture injury during the preceding year, 1 in 5 had exposure via mucous membranes, and more than half had worked at least once with a recent abrasion or cut on their hands. The number of injuries was independent of age (P=.26), duration of practice (P=.21), and workplace setting (P=.78). The percentage of nurses without percutaneous exposure during the preceding year was significantly higher in the group that received special HIV/AIDS training than in the group that did not (95% confidence interval, 5.8-24.1%; P<.002). The most recent exposure was primarily caused by hollow-bore needles, involved the palm and fingers II-V, was self-inflicted, took place during an elective procedure, and was not reported to the hospital's infection control center by 74% of respondents. The most common reason for not reporting the exposure (38% of cases) was the conviction that the source patient was not infected. CONCLUSIONS: Because of the large number of occupational exposures to blood, especially those due to injuries with hollow-bore needles, nurses should adopt more adequate behavioral strategies to prevent the transmission of blood-borne pathogens. Policies for providing adequate education programs tailored to encourage nurses to report all exposures are urgently required

168.    Ganczak M. [HIV infection under laboratory conditions]. Med Pr 2006; 57(4):353-358.
ABSTRACT: Laboratory workers are at a particularly high risk of acquiring HIV. Based on the medical literature, selected cases of occupational HIV infections among laboratory workers are presented. Having analyzed specific circumstances connected with occupational exposures, risk factors of such incidents are discussed. The importance of continuing education in the areas of infection control procedures and compliance with universal precautions as well as reporting on occupational exposures to any infectious material in the context of post-exposure prophylaxis are pointed as the best ways to achieve a successful outcome in the HIV infection prevention under laboratory conditions. The lack of efficient, multifaceted legislation covering all aspects of occupational exposure to blood-borne pathogens, still observed in Poland, is stressed

169.    Garmaise D. Health care workers push for use of safer hypodermic needles. HIV AIDS Policy Law Rev 2006; 11(1):18-19.
ABSTRACT: Unions in Ontario and British Columbia representing nurses and other health care workers are lobbying for safer hypodermic needles in hospitals, long-care facilities and other medical settings.

In Ontario, three unions representing health care workers have launched a CA$100,000-plus advertising campaign to seek public support for changing provincial labour laws and obtaining new health funding for safer equipment. NDP MPP Shelley Martel has introduced a private member's bill which would entrench in law the mandatory use of safety needles.

170.    Gisselquist D, Upham G, Potterat JJ. Efficiency of human immunodeficiency virus transmission through injections and other medical procedures: evidence, estimates, and unfinished business. Infect Control Hosp Epidemiol 2006; 27(9):944-952.
ABSTRACT: Objective. To estimate the transmission efficiency of human immunodeficiency virus (HIV) through medical injections and other invasive procedures.Design. We searched our own files and Medline (from 1966-2004, using the keywords ["iatrogenic" or "nosocomial" or "injections"] and "HIV") for reports of iatrogenic outbreaks worldwide, except outbreaks traced to receipt of contaminated blood or blood products. We also analyzed information from a case-control study of percutaneous exposures to healthcare workers.Setting. Worldwide healthcare settings.Events. We identified 8 iatrogenic outbreaks that met our study criteria; published information from 4 outbreaks was sufficient to estimate transmission efficiency.Results. From the 4 documented iatrogenic outbreaks, we estimated that 1 iatrogenic infection occurred after 8-52 procedures involving HIV-infected persons. Although only 0.3% of healthcare workers seroconvert after percutaneous exposure, a case-control study reported that deep injuries and other risk factors collectively increased seroconversion risk by as much as 50 times. Laboratory investigations demonstrate HIV survival through time and various rinsing regimens. We estimate that the transmission efficiency in medical settings with no or grossly insufficient efforts to clean equipment ranges from 0.5% to 3% for lower risk procedures (eg, intramuscular injections) and from 10% to 20% or more for high-risk procedures. Efforts to clean equipment, short of sterilization, may cut the transmission efficiency by 0%-100%. Procedures that contaminate multidose vials may accelerate transmission efficiency.Conclusion. To achieve better estimates of the transmission efficiency for a range of medical procedures and settings, investigations of iatrogenic outbreaks should be accorded high priority

171.    Gomaa A, Sinclair R, Alarcon W. Occupational blood-borne diseases in surgery.[comment]. American Journal of Surgery 2006; 192(3):408-409.
ABSTRACT: To the Editor: We read with great interest Dr. Fry's article "Occupational Blood-borne Diseases in Surgery" recently published by the American Journal of Surgery.  The article draws the conclusion that it is unlikely that we know all of the potential blood-borne pathogens that may pose an occupational risk for surgeons, that blood exposure in the operating room is tolerated with the same lassitude that chacterized the pre-HIV era, and that prevention of blood exposure is a desirable goal.

172.    Hagstrom AM. Perceived barriers to implementation of a successful sharps safety program. AORN J 2006; 83(2):391, 393-391, 397.
ABSTRACT: IN RESPONSE TO INCREASING needle sticks and sharps injuries at a large, urban trauma center in the northeastern United States, a nurse educator assembled a focus group of OR staff members to determine what they perceived to be barriers to successful implementation of a sharps safety program. THE FOCUS GROUP IDENTIFIED inadequate communication, powerlessness, resistance to change, intimidation, inconsistencies in practice, negative attitudes, inexperienced staff members, and time constraints as barriers to a successful change implementation. USING THIS INFORMATION, the nurse educator identified strategies to implement a practice change to decrease the rate of needle sticks and sharps injuries

173.    Haiduven D, Applegarth S, DiSalvo H, Mangipudy S, Konopack J, Fisher J. A pilot study to measure the compressive and tensile forces required to use retractable intramuscular safety syringes. Am J Infect Control 2006; 34(10):661-668.
ABSTRACT: BACKGROUND: A pilot study was conducted at the Tampa Veterans Administration Patient Safety Center. The objective was to determine the forces required to operate retractable safety syringes to evaluate potential adverse occupational health and patient safety issues. METHODS: Four brands (100 each) of retractable syringes were tested, using a digital force gauge, in air and in a simulated patient material (SPM). Compressive and tensile forces were measured while activating the retraction mechanism and withdrawing saline into the syringe barrel, respectively. RESULTS: The mean compressive force was greater in SPM than in air in all 4 devices. There was a statistically significant compressive force difference between activation in air and SPM in devices 1 and 2 (P </= .05). The tensile forces for all devices were lower than the compressive forces. Analysis of variance was used to compare the groups, and the results showed that the means were significantly different (P < .001). CONCLUSION: This pilot study has implications for device selection, training for users, design issues for manufacturers, and patient safety, as well as potential for future needlestick and ergonomic injuries. We recommend replication of this study with a computer-controlled force testing apparatus, and by testing multiple needle and syringe sizes

174.    Health Protection Agency Centre for Infections. Eye of the Needle: United Kingdom Surveillance of Significant Occupational Exposures to Bloodborne Viruses in Healthcare Workers. November 2006. 2006. Health Protection Agency Centre for Infections, National Public Health Service for Wales, CDSC Northern Ireland and Health Protection Scotland.
ABSTRACT: This report provides information on the risks for occupational exposure and seroconversion to bloodborne viruses in healthcare workers. In conjunction with monitoring and informing related policies, it provides recommendations for prevention and improving clinical management of significant occupational exposures to bloodborne viruses.

175.    Henry LB, Pellowski DM, Davis DA. Combination forceps fuse both safety and efficiency. Dermatol Surg 2006; 32(5):717-720.
ABSTRACT: BACKGROUND: Instrumentation prevents needle stick injury. OBJECTIVE: To review forceps that insure safety and facilitate tissue-handling and knot-tying efficiency. METHOD: Medical literature reports were reviewed using Ovid. Commercially available instruments were qualitatively tested. RESULTS: Suture platforms securely hold suture needles and can be used during knot tying. A wide range of combination forceps have been invented and can be broadly categorized as either skin hook or toothed combination forceps. CONCLUSIONS: Combination forceps fuse both efficiency and safety. Skin hook forceps may eventually be the optimal combination instrument, but toothed combination forceps are recommended

176.    Herida M, Larsen C, Lot F et al. Cost-effectiveness of HIV post-exposure prophylaxis in France.[see comment]. AIDS 2006; 20(13):1753-1761.
ABSTRACT: OBJECTIVE: To assess the cost-effectiveness of HIV post-exposure prophylaxis (PEP) in France. METHODS: We used a decision tree to evaluate, from a society's perspective, the cost of PEP per quality-adjusted life-year (QALY) saved. We used 1999-2003 PEP surveillance data and literature-derived data on per event transmission probabilities, PEP efficacy and quality of life with HIV. HIV prevalence and lifetime cost of HIV/AIDS management in the HAART era were derived from French studies. We assumed that mean life expectancy in full health was 65 years among uninfected individuals and that the mean survival time after HIV infection was 22.5 years. The costs of PEP drugs and follow-up were derived from the French public sector. A 3% annual rate was used to discount future costs and effects. RESULTS: During 1999-2003, PEP was prescribed to 8958 individuals (heterosexual sex: 47.6%; homosexual sex: 28.4%; occupational exposure: 23.4%; drug injection: 0.6%); of those, 2143 were exposed to a known HIV-infected source. PEP was estimated to prevent 7.7 infections and saved 64.5 QALY at a net cost of euro 5.7 million, resulting in an overall cost-effectiveness ratio of euro 88,692 per QALY saved. PEP was cost saving for 4.4% of cases and cost effective (< euro 50,000 per QALY) in a further 11.3% of cases. In contrast, 72 and 52% of prescriptions had a cost-effectiveness ratio exceeding euro 200,000 and euro 2 millions, respectively, per QALY saved. CONCLUSION: Overall, the French PEP programme is only moderately cost effective. PEP guidelines should be revised to target high-risk exposures better

177.    Hoofnagle JH, Seeff LB. Peginterferon and ribavirin for chronic hepatitis C. [Review] [50 refs]. New England Journal of Medicine 2006; 355(23):2444-2451.
ABSTRACT: A 44-year-old woman with chronic hepatitis C has intermittent fatigue and persistent elevations in serum alanine aminotransferase levels. She has had hepatitis C for 10 years. The diagnosis was made after she attempted to donate blood and was found to have antibodies against the hepatitis C virus (HCV). On questioning, she reports having used illicit injection drugs in her early 20s.
The physical examination is normal except for obesity. The results  of laboratory tests show an alanine aminotransferase level of 86 U per liter (normal value, <42); the alkaline phosphatase level, direct and total bilirubin levels, albumin level, prothrombin time, and complete blood count are normal. The serum HCV RNA level is 3.5 million IU per milliliter (genotype 1), and a liver biopsy specimen shows bridging fibrosis. The patient is evaluated by a hepatologist, who recommends treatment with pegylated interferon and ribavirin.

178.    Hsieh WB, Chiu NC, Lee CM, Huang FY. Occupational blood and infectious body fluid exposures in a teaching hospital: a three-year review. J Microbiol Immunol Infect 2006; 39(4):321-327.
ABSTRACT: BACKGROUND AND PURPOSE: Blood and infectious body fluid (BBF) exposures are common safety problems for health care workers (HCWs). We analyzed reported BBF exposures during a 3-year period at a teaching hospital. METHODS: We collected reports of BBF exposures among HCWs occurring from January 2001 to December 2003 at a 2000-bed tertiary care medical center in northern Taiwan. HCWs were requested to report BBF exposures immediately after each exposure, which required completing a report sheet of questions concerning the exposure. The HCW was also required to visit an infectious diseases specialist who would decide on the appropriate management in each case. RESULTS: Needlestick injuries were the most commonly reported BBF exposure, accounting for 80% of reported cases. The total incidence density of BBF exposures was 1.96 per 100 person-years. BBF exposures were most common in December and least common in September. Nurses had the highest percentage (60.6%) of BBF exposures and other job categories including physicians, technicians, cleaning staff, and interns accounted for around 10% each. Injuries occurred most commonly during the daytime (57.0%). Three-quarters (74.9%) of the injured HCWs had appropriate immediate care. Interns had the highest incidence density (4.48 per 100 person-years) of BBF exposures and technicians the lowest (0.50 per 100 person-years). Among the exposed HCWs, 1 received hepatitis B vaccine, 1 received both hepatitis B vaccine and hepatitis B immune globulin, 1 received zidovudine/lamivudine due to a needlestick injury when treating an HIV-positive patient, and 4 received penicillin due to exposure to syphilis. No HCW developed infections after BBF exposure during the study period. CONCLUSIONS: Measures which may be effective in reducing BBF exposures include education of HCW, increased use of standard precautions, improved administrative support, and enhanced reporting of BBF exposures

179.    Ibekwe RC, Ibeziako N. Hepatitis B vaccination status among health workers in Enugu, Nigeria. Nigerian Journal of Clinical Practice 2006; 9(1):7-10.
ABSTRACT: BACKGROUND: Health workers in Nigeria are particularly at increased risk of contracting hepatitis B virus in their work place because Nigeria is a holoendemic area. Hepatitis B vaccination virtually eliminates this risk. There are few studies on the perception and uptake of hepatitis B vaccination among health workers in Nigeria and none to our knowledge in the University of Nigeria Teaching Hospital (UNTH), Enugu. OBJECTIVE: To determine the Hepatitis B vaccination level among all categories of health workers in UNTH, Enugu, and the factors that influence its uptake. METHOD: The study was cross-sectional in design. Subjects were health workers likely to be exposed to patients and or their body fluids. The tool was a self administered pre-tested questionnaire and analysis was done using SPSS version 11.5 software. RESULTS: Fifty point four percent of the health workers felt that their jobs exposed them to an increased risk of contracting hepatitis B virus infection. There is a significant occupational difference in perception with only 5.5% of the ward attendants as against 67.9% of other workers feeling that their jobs exposed them to increased risk (P = 0.00). Twenty two point four percent had received Hepatitis B vaccination, 3.7% had received 3 or more doses. Only years of occupational practice had a significant influence on vaccination uptake (P = 0.00). The most common reason for non-vaccination was lack of opportunity (43.08%). Among the 53.7% of the respondents who had had needle stick injury, none received post exposure prophylaxis. CONCLUSION: There is a low level of hepatitis B vaccination and no post exposure prophylaxis among health workers in UNTH, Enugu. This is due to poor perception of the risk of contracting this infection and non-availability of the vaccines

180.    Ilhan MN, Durukan E, Aras E, Turkcuoglu S, Aygun R. Long working hours increase the risk of sharp and needlestick injury in nurses: the need for new policy implication. J Adv Nurs 2006; 56(5):563-568.
ABSTRACT: AIM: This paper reports a study to determine the sharp and needlestick injury incidence in nurses working at a university hospital and the contributing factors. BACKGROUND: Although it is generally felt that working in the healthcare sector is clean and without risk, healthcare staff and especially physicians and nurses who generally work very long hours are actually exposed to various occupational risks. Sharps and needlestick injuries are important problems for healthcare workers as they increase the risk of spread of infection. METHOD: A self-administered questionnaire was completed in October 2005 by 449 of the 516 nurses working at a Turkish hospital (response rate 87.0%). RESULTS: The percentage of nurses experiencing a sharp or needlestick injury during their professional life was 79.7%. The incidence of exposure to sharp or needlestick injury in the last year was 68.4%. The factors increasing the rate of sharp and needlestick injury were: age 24 years and less, <or=4 years of nursing experience, working in surgical or intensive care units and working for more than 8 hours per day (P < 0.05). CONCLUSION: The findings indicate which groups of staff should be targeted for educational programmes. Consideration also needs to be given to the unwanted effects of working long shifts, where tiredness may contribute to the number of needlestick injuries

181.    Ilhan MN, Durukan E, Aras E, Turkcuoglu S, Aygun R. Long working hours increase the risk of sharp and needlestick injury in nurses: the need for new policy implication. J Adv Nurs 2006; 56(5):563-568.
ABSTRACT: AIM: This paper reports a study to determine the sharp and needlestick injury incidence in nurses working at a university hospital and the contributing factors. BACKGROUND: Although it is generally felt that working in the healthcare sector is clean and without risk, healthcare staff and especially physicians and nurses who generally work very long hours are actually exposed to various occupational risks. Sharps and needlestick injuries are important problems for healthcare workers as they increase the risk of spread of infection. METHOD: A self-administered questionnaire was completed in October 2005 by 449 of the 516 nurses working at a Turkish hospital (response rate 87.0%). RESULTS: The percentage of nurses experiencing a sharp or needlestick injury during their professional life was 79.7%. The incidence of exposure to sharp or needlestick injury in the last year was 68.4%. The factors increasing the rate of sharp and needlestick injury were: age 24 years and less, <or=4 years of nursing experience, working in surgical or intensive care units and working for more than 8 hours per day (P < 0.05). CONCLUSION: The findings indicate which groups of staff should be targeted for educational programmes. Consideration also needs to be given to the unwanted effects of working long shifts, where tiredness may contribute to the number of needlestick injuries

182.    International Healthcare Worker Safety Center. Checklist for Sharps Injury Prevention. Managing Infection Control 2006; October 2006:16-18.
ABSTRACT: Chestlist for Sharps Injury Prevention

183.    Jagger J, Perry JL. Response to Mallolas et al. "Obstetrician-to-patient HIV transmission". AIDS 2006; 20(13):1785-1786.
ABSTRACT: The report of Mallolas et al. is an important confirmation that, although uncommon, HIV can be transmitted from an infected healthcare worker (HCW) to a patient via a needlestick injury during an exposure-prone procedure. The actions of the obstetrician in this case raise some important issues.

First, although the obstetrician was in a known risk group for HIV infection, he declined to know his HIV status before infecting a patient, in contradiction to recommendations cited by the authors. By knowing his HIV status he could have eliminated or reduced his risk of infecting a patient by refraining from performing invasive procedures or by eliminating the use of sharp-tip suture needles from caesarean and other obstetric procedures (substituting blunt suture needles instead), and also by receiving antiretroviral therapy, which can reduce the viral load in the blood of an infected individual.

184.    Jagger J, Perry JL. Response to Mallolas et al. "Obstetrician-to-patient HIV transmission". AIDS 2006; 20(13):1785-1786.
ABSTRACT: The report of Mallolas et al. [1] is an important confirmation that, although uncommon, HIV can be transmitted from an infected healthcare worker (HCW) to a patient via a needlestick injury during an exposure-prone procedure. The actions of the obstetrician in this case raise some important issues.

185.    Jovic-Vranes A, Jankovic S, Vranes B. Safety practice and professional exposure to blood and blood-containing materials in serbian health care workers. Journal of Occupational Health 2006; 48(5):377-382.
ABSTRACT: Safety practice is an important element of workplace safety and quality of health care. To investigate the safety practice and professional exposure to blood and blood-containing materials during a one-year period among Health Care Workers (HCWs) in Serbia. Cross-sectional study of 1559 Serbian HCWs using a self-administered questionnaire. Mantel-Haenszel statistics and multiple logistic regression analysis were used in statistical analysis. Fifty-nine percent (921) of HCWs had skin contact with patients blood, followed by 51% (791) with needle stick injuries, 38% (599) with cuts from sharp instruments, and 34% with contact of eye and other mucosa with patient's blood. Nurses reported professional exposure more often than others. Safety practices consisted of using appropriate barriers (gloves, mask, glasses) in all procedures with patients and were used by 58%, 23%, and 4% of HCWs, respectively. Doctors protected themselves more regularly than others. Hospital protocols for post exposure prophylaxis and safety disposal of medical waste are not common in Serbian health care settings. Safety practices in use were having hospital guidelines for safety practice in hospitals [odds ratio (OR)=1.58, 95% confidence interval (CI)=1.14-2.19], carrying out some form of intervention with risks of infection (OR=3.76, 95% CI=2.57-5.51), and HCWs aware of the professional risk of acquiring infection (OR=1.48, 95% CI=1.28-1.79). This study indicates that emphasis on work practice, attire, disposal systems and education strategies, should be employed to reduce professional exposure to blood and blood containing materials among HCWs in Serbia

186.    Kanter L. Accidental needle stick prevention: an important, costly, unsafe policy revisited. Ann Allergy Asthma Immunol 2006; 97(1):7-9.
ABSTRACT: The article by Wolf et al in this issue of the Annals addresses important medicoeconomic and disease transmission and safety issues. Because of the number of injections administered at an allergy practice, sharp object containers are usually kept within immediate reach of the employee giving shots. Activating a needle guard mechanism after giving the injection adds an additional action, thereby potentially increasing the opportunity for accidental needle sticks (ANSs).

In 1984, the first case of needle stick-transmitted human immunodeficiency virus (HIV) was reported.  In 1986, the Occupational Safety and Health Administration (OSHA) was petitioned by various unions representing health care employees to develop a standard that protects employees from occupational exposure to bloodborne diseases.  The US Congress subsequently passed the Needlestick Safety and Prevention Act. This act, which passed on January 18, 2001, and became effective on April 18, 2001, directed OSHA to revise the bloodborne pathogens standard.  This revision specifies that "safer medical devices, such as sharps with engineered sharps injury protections and needle-less systems" constitute "an effective" engineering control and must be used where feasible. There was no definition of "effective" or "safer" or the need to validate before use.

187.    Keeler N, Schonberger LB, Belay ED, Sehulster L, Turabelidze G, Sejvar JJ. Investigation of a possible iatrogenic case of Creutzfeldt-Jakob disease after a neurosurgical procedure. [Review] [15 refs]. Infection Control & Hospital Epidemiology 2006; 27(12):1352-1357.
ABSTRACT: OBJECTIVE: To investigate a case of Creutzfeldt-Jakob disease (CJD) possibly acquired from contaminated neurosurgical instruments. DESIGN: Retrospective review of medical records, hospital databases, service log books, and state vital statistics. SETTING: A tertiary care hospital (hospital A) in Missouri. PATIENTS: The case patient was a 38-year-old African American woman with a 9-month history of progressive memory loss, visual disturbances, and dementia. She underwent neurosurgery in November 1996. CJD was confirmed in April 2004 by immunodiagnostic testing of brain biopsy samples. All patients who underwent neurosurgery at the same hospital within 6 months before or after the case patient's procedure were identified and investigated for preoperative or postoperative evidence of CJD. RESULTS: We reviewed data on 268 neurosurgical procedures, 84 pathology log entries, and 60 death certificates for neurosurgical patients at hospital A and identified 2 suspected cases of CJD. Clinical features and definitive prion testing of stored brain biopsy samples excluded a diagnosis of CJD. Standard operating room procedures were in place, but specific protocols for handling instruments potentially contaminated with prions were not used. CONCLUSIONS: Neurosurgical instruments were not implicated as the source exposure for CJD in the case patient. The 2 patients with suspected CJD were identified from different data sources, suggesting good internal consistency in data collection. The key elements of this investigation are suggested for use in future investigations into potential cases of iatrogenic CJD. [References: 15]

188.    Krishnan P, Dick F, Murphy E. The impact of educational interventions on primary health care workers' knowledge of occupational exposure to blood or body fluids. Occup Med (Lond) 2006; Advance Access.
ABSTRACT: Aim To assess the impact of educational interventions on primary health care workers' knowledge of management of occupational exposure to blood or body fluids. Methods Cluster-randomized trial of educational interventions in two National Health Service board areas in Scotland. Medical and dental practices were randomized to four groups; Group A, a control group of practices where staff received no intervention, Group B practices where staff received a flow chart regarding the management of blood and body fluid exposures, Group C received an e-mail alert containing the flow chart and Group D practices received an oral presentation of information in the flow chart. Staff knowledge was assessed on one occasion, following the educational intervention, using an anonymous postal questionnaire. Results Two hundred and fifteen medical and dental practices were approached and 114 practices participated (response rate 53%). A total of 1120 individual questionnaires were returned. Face to face training was the most effective intervention with four of five outcome measures showing better than expected knowledge. Seventy-seven percent of staff identified themselves as at risk of exposure to blood and body fluids. Twenty-one percent of staff believed they were not at risk of exposure to blood-borne viruses although potentially exposed and 16% of exposed staff had not been immunized against hepatitis B. Of the 856 'at risk' staff, 48% had not received training regarding blood-borne viruses. Conclusions We found greater knowledge regarding management of exposures to blood and body fluids following face to face training than other educational interventions. There is a need for education of at risk primary health care workers

189.    Kubiczek P, Langona M, Mellen PF. Occupational injuries in a pathology residency program.[comment]. Archives of Pathology & Laboratory Medicine 2006; 130(2):146-147.
ABSTRACT: To the Editor: We read with interest the article "Cutting Injuries in an Academic Pathology Department," by Pritt and Waters, and wish to share our observations and experiences on this topic.  We reviewed reports of occupational injuries from May 2000 through May 2003 occurring at the Ball Memorial Hospital Pathology Residency program.  This 400-bed community hospital with academic residency programs in multiple specialities processed 857 autopsies (mostly forensic) and 80,000 surgical pathology cases during this period.

190.    L'Heriteau F, Tarantola A, Olivier M et al. Variation in blood and body fluids exposure when small-gauge needles or peripheral venous catheters were implicated: results of a 4-year surveillance in France. Am J Infect Control 2006; 34(4):215-217.
ABSTRACT: The blood and body fluids exposure (BBFE) risk for health care workers varies according to numerous factors. Based on a needlestick surveillance in 13 French hospitals from 1997 to 2000, we evaluated incidence and temporal trends of BBFE according to medical devices causing needlestick injuries. We observed that the BBFE incidence per 100,000 peripheral venous catheters purchased decreased from 12.9 to 4.9, whereas incidence per 100,000 subcutaneous needles purchased increased from 8.7 to 14.3

191.    Leens E, Van Laer F. Accidents exposant au sang au bloc opératoire. NOSO 2006; 10(3):4-9.
ABSTRACT: 'Sur la base des résultats du réseau de surveillance national des AES, cet article vise à offrir une meilleure compréhension du risque encouru par le personnel du bloc opératoire. Nous nous intéresserons de plus près au nombre et au type d' AES, aux circonstances des infections, au type de matériel utilisé lors de l'incident et aux mesures de prévention à prendre pour minimiser le risque dans le contexte spécifique du bloc opératoire.'

192.    Leiss J, Ratcliff JM, Lyden JT et al. Blood Exposure Among Paramedics: Incidence Rates From the National Study to Prevent Blood Exposure in Paramedics. Annals of Epidemiology 2006; 16(9):720-725.
ABSTRACT: Purpose The aim of the study is to estimate incidence rates of occupational blood exposure by route of exposure (needlesticks; cuts from sharp objects; mucous membrane exposures to the eyes, nose, or mouth; bites; and blood contact with nonintact skin) in US and California paramedics.
Methods A mail survey was conducted in a national probability sample of certified paramedics.
Results Proportions of paramedics who reported an exposure in the previous year were 21.6% (95% confidence interval [CI], 17.8–25.3) for the national sample and 14.8% (95% CI, 12.2–17.4) for California. The overall incidence rate was 6.0/10,000 calls (95% CI, 3.9–8.1). These rates represent more than 49,000 total exposures and more than 10,000 needlesticks per year among paramedics in the United States. Rates for mucocutaneous exposures and needlesticks were similar (1.2/10,000 calls). Rates for California were one third to one half the national rates. Sensitivity analysis showed that potential response bias would have little impact on the policy and intervention implications of the findings.
Conclusion Paramedics continue to be at substantial risk for blood exposure. More attention should be given to reducing mucocutaneous exposures. The impact of legislation on reducing exposures and the importance of nonintact skin exposures need to be better understood.

193.    Liu CH, Chen BF, Chen SC, Lai MY, Kao JH, Chen DS. Selective transmission of hepatitis C virus quasi species through a needlestick accident in acute resolving hepatitis. Clin Infect Dis 2006; 42(9):1254-1259.
ABSTRACT: BACKGROUND: Little is known about the transmission of variant hepatitis C virus (HCV) genome through needlestick injuries. METHODS: To demonstrate how HCV quasi species are transmitted and adapt to the new host in acute resolving infection, we analyzed the nucleotide and deduced amino acid sequences of the hypervariable region 1 (HVR-1) in the E2 domain of HCV in both the source of the virus ("donor") and the person who received the virus through a needlestick accident ("recipient"). In addition, we also performed phylogenetic analysis of HCV quasi species in these patients to document the viral transmission. RESULTS: We obtained a total of 33 clones at different time points by using polymerase chain reaction amplification and cloning and sequencing of HVR-1. A predominant HVR-1 variant (in 4 of 10 isolates) in the donor was not present in the recipient 6 and 14 weeks after the accident. In contrast, a minor variant (in 1 of 10 isolates) in the donor became the predominant strain in the recipient 6 weeks (in 10 of 12 isolates) and 14 weeks (in 6 of 11 isolates) after the accident. Additional phylogenetic analysis showed high homology of nucleotide sequences between isolates obtained from the donor and isolates obtained from the recipient. In addition, the variants in the recipient's virus showed substantial genetic preservation in the course of acute resolving hepatitis. CONCLUSIONS: These data suggested that a minor HCV variant from a donor was transmitted to the recipient through a needlestick injury and that it prevailed as the dominant species. The preserved genetic homogeneity of the transmitted viral variants in patients with acute HCV infection may account for their clinical outcomes of resolving hepatitis

194.    Makary MA, Pronovost PJ, Weiss ES et al. Sharpless surgery: a prospective study of the feasibility of performing operations using non-sharp techniques in an urban, university-based surgical practice. World Journal of Surgery 2006; 30(7):1224-1229.
ABSTRACT: CONTEXT: Percutaneous injuries occur frequently during surgical procedures and represent a significant occupational hazard to operating room personnel. OBJECTIVES: To evaluate the feasibility of performing select general surgical procedures using a combination of non-sharp devices and techniques to replace the conventional use of scalpels and needles. DESIGN, SETTING, AND PARTICIPANTS: Candidate procedures for which sharpless techniques could replace conventional scalpels and suture needles were identified preoperatively in an urban, university-based general surgical practice over a 1-year period (June 2003-June 2004). Non-sharp techniques included monomeric 2-octyl cyanoacrylate adhesive, electrocautery, tissue stapler, and minimally invasive instrumentation. Conventional scalpels and suture needles were readily available and used whenever necessary. MAIN OUTCOME MEASURES: We rated the feasibility of performing specific procedures without sharps. We also documented the rate of overall reversion to sharps during operations on patients that had been identified preoperatively as candidates for sharpless surgery. RESULTS: Of 358 procedures performed in the general surgery university practice, 91 were identified preoperatively as appropriate for sharpless surgery. Of these, 86.8% (79/91) were completed without the use of sharps, including 13/22 (59.1%) open laparotomy procedures, 20/22 (90.9%) laparoscopic procedures, and 46/47 (97.8%) soft tissue procedures. Intraoperative reversion to sharps occurred in 12 cases when deemed necessary by the surgeon. CONCLUSIONS: Select common procedures can be performed entirely with sharpless techniques, eliminating the risk to surgical personnel associated with intraoperative percutaneous injuries

195.    Mallolas J, Arnedo M, Pumarola T et al. Transmission of HIV-1 from an obstetrician to a patient during a caesarean section. AIDS 2006; 20(2):285-299.
ABSTRACT: We describe a probable case of HIV-1 transmission from a healthcare worker (HCW) to a patient during a caesarean section. Genetic distance comparisons of the viral sequence of the C2V4 region of the viruses from the patient and the obstetrician showed an average nucleotide sequence divergence of 3% (2.8-3.1). HIV can be transmitted from an infected HCW to a patient when percutaneous injuries with subsequent exposure of the patient to the blood of the HCW can occur.

196.    Mallolas J, Arnedo M, Pumarola T et al. Transmission of HIV-1 from an obstetrician to a patient during a caesarean section. AIDS 2006; 20(2):285-287.
ABSTRACT: We describe a probable case of HIV-1 transmission from a healthcare worker (HCW) to a patient during a caesarean section. Genetic distance comparisons of the viral sequence of the C2V4 region of the viruses from the patient and the obstetrician showed an average nucleotide sequence divergence of 3% (2.8-3.1). HIV can be transmitted from an infected HCW to a patient when percutaneous injuries with subsequent exposure of the patient to the blood of the HCW can occur

197.    Mallolas J, Gatell JM, Bruguera M. Transmission of HIV-1 from an obstetrician to a patient during a caesarean section. AIDS 2006; 20(13):1785.
ABSTRACT: We have recently reported [1] a probable case of the transmission of HIV-1 from an obstetrician to a patient during a caesarean section. In response to a request from the editors for clarification of the HIV testing that took place and in response to a reader's query, so that others are aware of the details available on this report of HIV transmission between a healthcare professional and a patient, we would like to underline and or reinforce the following points: (i) The HIV-negative test during pregnancy was reported by the patient only, and any results for screening for HIV-1 antibodies and viral load could not be directly verified.

198.    Menna-Barreto M. HTLV-II transmission to a health care worker. Am J Infect Control 2006; 34(3):158-160.
ABSTRACT: Health care workers, mainly in emergency and forensic services, are at risk of exposure to bloodborne pathogens. Human T-cell lymphotropic virus type I and type II (HTLV-I and HTLV-II) are cosmopolitan human delta retroviruses causing endemic infection in Japan, the Caribbean basin, South America, and sub-Saharan Africa, and in clusters among intravenous drug users in Europe and the United States. The seroprevalence of HTLV-I and HTLV-II among Brazilian blood donors ranges from 0.08% to 1.35%. HTLV-I transmission to a Japanese researcher has already been reported. We describe the transmission of HTLV-II infection to a Brazilian laboratory worker caused by a needlestick injury when she was recapping a syringe after collecting material for arterial blood gas analysis. To our knowledge, this is the first report of an occupational transmission of HTLV-II to a health care worker

199.    Motamed N, BabaMahmoodi F, Khalilian A, Peykanheirati M, Nozari M. Knowledge and practices of health care workers and medical students towards universal precautions in hospitals in Mazandaran Province. Eastern Mediterranean Health Journal 2006; 12(5):653-661.
ABSTRACT: This study investigated knowledge of and practices towards universal precautions among 540 health care workers and medical students in 2 university hospitals in Mazandaran Province, Islamic Republic of Iran. Only 65.8% and 90.0% staff in the 2 hospitals and 53.5% of medical students had heard about universal precautions. Overall, there was a low understanding of precautions, except concerning disposal of sharps, contact with vaginal fluid, use of mask and gown or cleaning spilled blood. Health workers had difficulty distinguishing between deep body fluids and body secretions that are not considered infectious. Good practices were reported regarding hand-washing, disposal of needles, and glove, mask and gown usage

200.    Pan A, Signorini L, Magri S, De Carli G. Scalp needlestick injury during fine-needle aspiration cytologic evaluation without needle manipulation: William tell in the laboratory, not quite. Infect Control Hosp Epidemiol 2006; 27(9):996.
ABSTRACT: To The Editor--Galed-Placed et al. suggest using a modified method of fine-needle aspiration cytologic evaluation (FNAC) that eliminates manipulation of the contaminated needle to reduce the risk of occupational infection in healthcare personnel while retaining diagnostic accuracy.  The modified method of FNAC eliminates excess needle manipulation by aspirating 2 ml. of air into the syringe so that, subsequent to the procedure, the residual air can be used to empty the material in the needle.  We describe a case of scalp injury in a cytopathologist who used this modified method of FNAC.

201.    Pellissier G, Migueres B, Tarantola A, Abiteboul D, Lolom I, Bouvet E. Risk of needlestick injuries by injection pens. J Hosp Infect 2006; 63(1):60-64.
ABSTRACT: Injection pens are used by patients when auto-administering medication (insulin, interferon, apokinon etc.) by the subcutaneous route. The objective of this study was to evaluate the rate of injection pen use by healthcare workers (HCWs) and the associated risk of needlestick injuries to document and compare injury rates between injection pens and subcutaneous syringes. A one-year retrospective study was conducted in 24 sentinel French public hospitals. All needlestick injuries linked to subcutaneous injection procedures, which were voluntarily reported to occupational medicine departments by HCWs between October 1999 and September 2000, were documented using a standardized questionnaire. Additional data (total number of needlestick injuries reported, number of subcutaneous injection devices purchased) were collected over the same period. A total of 144 needlestick injuries associated with subcutaneous injection were reported. The needlestick injury rate for injection pens was six times the rate for disposable syringes. Needlestick injuries with injection pens accounted for 39% of needlestick injuries linked with subcutaneous injection. In all, 60% of needlestick injuries with injection pens were related to disassembly. Injection pens are associated with needlestick injuries six times more often than syringes. Nevertheless, injection pens have been shown to improve the quality of treatment for patients and may improve treatment observance. This study points to the need for safety-engineered injection pens

202.    Perry J, Jagger J. Waking up to the benefits of safety I.V. catheters. Nursing2006 2006; 36(2):68.
ABSTRACT: Injuries to nurses from conventinal I.V. catheters declined by 55% from 1993 to 2001.  The most recent data from the Exposure Prevention Information Network (EPINet) shown an even bigger drop: From 2001 to 2004, injuries decreased by another 63%.  This can be directly correlated to the implementation of I.V. safety catheters, which had captured 94% of the U.S. I.V. catheter acute care market as of 2004.  Implementation of safety I.V. catheters has become a priority in most U.S. health care facilities--especially since the Needlestick Safety and Prevention Act mandated the use of safety devices in 2000.

203.    Perry JL, Pearson RD, Jagger J. Infected health care workers and patient safety: A double standard. Am J Infect Control 2006; 34(5):313-319.
ABSTRACT: US policy regarding health care worker-to-patient transmission of bloodborne pathogens, issued in 1991, is flawed. We review current evidence of such nosocomial infections and conclude that a standardized national policy is needed, which includes improved surveillance and follow-up of blood exposures to patients and targeted practice restrictions for infected practitioners performing exposure-prone procedures

204.    Prati D, Prati D. Transmission of hepatitis C virus by blood transfusions and other medical procedures: a global review. [Review] [112 refs]. Journal of Hepatology 2006; 45(4):607-616.
ABSTRACT: Hepatitis C virus (HCV) is a leading cause of chronic blood-borne infection and chronic liver disease. The global epidemic of HCV infection emerged in the second half of the 20th century, and several lines of evidence indicate that it was primarily triggered and fed iatrogenically by the increasing use of parenteral therapies and blood transfusion. In developed countries, the rapid improvement of healthcare conditions and the introduction of anti-HCV screening for blood donors have led to a sharp decrease in the incidence of iatrogenic hepatitis C, but the epidemic continues to spread in developing countries, where the virus is still transmitted through unscreened blood transfusions and non-sterile injections. This article reviews the published literature concerning HCV transmission through blood transfusions and other unsafe medical procedures. Given the substantial difference in current disease transmission patterns between the northern and southern hemispheres, the situation in developed and developing countries is separately analysed. [References: 112]

205.    Raghavendran S, Bagry HS, Leith S, Budd JM. Needle stick injuries: a comparison of practice and attitudes in two UK District General Hospitals. Anaesthesia 2006; 61(9):867-872.
ABSTRACT: Hospital staff are at risk from occupational exposure to blood-borne viruses due to needle stick injuries. Occupational health departments have invested considerable resources in the prevention of these injuries, which can be very distressing to the affected individuals. We surveyed health care workers, i.e. doctors, nurses and operating department practitioners, in the operating theatre and critical care units of two UK hospitals located in the Midlands and Merseyside to compare attitudes and experiences. There were significant deficiencies in several aspects of the safe practice of universal precautions. These deficiencies were similar in the two hospitals surveyed and may reflect a national trend. We conclude that every individual, department and trust needs to reflect on their practice and address these deficiencies

206.    Rapparini C. Occupational HIV infection among health care workers exposed to blood and body fluids in Brazil. Am J Infect Control 2006; 34(4):237-240.
ABSTRACT: BACKGROUND: Exposure to bloodborne pathogens poses a serious risk to health care workers (HCWs). Surveillance systems of occupationally acquired human immunodeficiency virus (HIV) infection have been developed in several countries, mainly in the developed world. The purpose of this study was to identify cases of occupationally acquired HIV infection among HCWs in Brazil. METHODS: A systematic literature review was conducted. The databases searched were MEDLINE and LILACS (1981 to 2004), academic dissertations and theses (1987 to 2004), ABSTRACTs from national and international meetings during the last 10 years, and local and national bulletins. Reference lists to identify other relevant articles were checked. RESULTS: The database searches generated a total of 60,770 titles. Two hundred and nineteen references were finally analyzed. Four documented cases of occupational HIV infection were identified. All of the cases involved nursing staff and were percutaneous exposures. Seventy-five percent occurred after a procedure involving a needle placed directly into a vein or artery. Most (75%) had source patients with probable high viral load and low CD4 count. Two cases represented HIV seroconversion despite initiation of postexposure prophylaxis. Only one case (1/4; 25%) presented acute retroviral illness. CONCLUSION: After an extensive literature search, 4 documented occupational HIV infection cases were identified, only 1 of which had been published in a scientific journal. Our findings were consistent with the majority of documented infections worldwide. Surveillance systems are indispensable to establish and formulate rational policies for minimizing the risk of occupational infection, not only from HIV but also from hepatitis B and C viruses and other bloodborne pathogens

207.    Rogers DE, Brent AC. Small-scale medical waste incinerators--experiences and trials in South Africa. Waste Manag 2006; 26(11):1229-1236.
ABSTRACT: Formal waste management services are not accessible for the majority of primary healthcare clinics on the African continent, and affordable and practicable technology solutions are required in the developing country context. In response, a protocol was established for the first quantitative and qualitative evaluation of relatively low cost small-scale incinerators for use at rural primary healthcare clinics. The protocol comprised the first phase of four, which defined the comprehensive trials of three incineration units. The trials showed that all of the units could be used to render medical waste non-infectious, and to destroy syringes or render needles unsuitable for reuse. Emission loads from the incinerators are higher than large-scale commercial incinerators, but a panel of experts considered the incinerators to be more acceptable compared to the other waste treatment and disposal options available in under-serviced rural areas. However, the incinerators must be used within a safe waste management programme that provides the necessary resources in the form of collection containers, maintenance support, acceptable energy sources, and understandable operational instructions for the incinerators, whilst minimising the exposure risks to emissions through the correct placement of the units in relation to the clinic and the surrounding communities. On-going training and awareness building are essential in order to ensure that the incinerators are correctly used as a sustainable waste treatment option

208.    Rogers DE, Brent AC. Small-scale medical waste incinerators--experiences and trials in South Africa. Waste Management 2006; 26(11):1229-1236.
ABSTRACT: Formal waste management services are not accessible for the majority of primary healthcare clinics on the African continent, and affordable and practicable technology solutions are required in the developing country context. In response, a protocol was established for the first quantitative and qualitative evaluation of relatively low cost small-scale incinerators for use at rural primary healthcare clinics. The protocol comprised the first phase of four, which defined the comprehensive trials of three incineration units. The trials showed that all of the units could be used to render medical waste non-infectious, and to destroy syringes or render needles unsuitable for reuse. Emission loads from the incinerators are higher than large-scale commercial incinerators, but a panel of experts considered the incinerators to be more acceptable compared to the other waste treatment and disposal options available in under-serviced rural areas. However, the incinerators must be used within a safe waste management programme that provides the necessary resources in the form of collection containers, maintenance support, acceptable energy sources, and understandable operational instructions for the incinerators, whilst minimising the exposure risks to emissions through the correct placement of the units in relation to the clinic and the surrounding communities. On-going training and awareness building are essential in order to ensure that the incinerators are correctly used as a sustainable waste treatment option

209.    Sadoh WE, Fawole AO, Sadoh AE, Oladimeji AO, Sotiloye OS. Practice of universal precautions among healthcare workers. J Natl Med Assoc 2006; 98(5):722-726.
ABSTRACT: INTRODUCTION: Healthcare workers (HCWs) are exposed to bloodborne infections by pathogens, such as HIV, and hepatitis B and C viruses, as they perform their clinical activities in the hospital. Compliance with universal precautions has been shown to reduce the risk of exposure to blood and body fluids. This study was aimed at assessing the observance of universal precautions by HCWs in Abeokuta, Ogun State, Nigeria. SUBJECTS AND METHODS: The study was conducted in September 2003 in Abeokuta metropolis, Ogun State, Nigeria. The respondents were doctors, trained and auxiliary nurses, laboratory scientists and domestic staff. They were selected through a multistage sampling technique from public and private healthcare facilities within the metropolis. The instrument was an interviewer-administered, semistructured questionnaire that assessed the practice of recapping and disposal of used needles, use of barrier equipment, handwashing and screening of transfused blood. RESULTS: There were 433 respondents, 211 (48.7%) of which were trained nurses. About a third of all respondents always recapped used needles. Compliance with nonrecapping of used needles was highest among trained nurses and worst with doctors. Less than two-thirds of respondents (63.8%) always used personal protective equipment, and more than half of all respondents (56.5%) had never worn goggles during deliveries and at surgeries. The provision of sharps containers and screening of transfused blood by the institutions studied was uniformly high. A high percentage (94.6%) of HCWs observed handwashing after handling patients. The use of barrier equipment was variable in the institutions studied. CONCLUSION: Recapping of used needles is prevalent in the health facilities studied. Noncompliance with universal precautions place Nigerian HCWs at significant health risks. Training programs and other relevant measures should be put in place to promote the appropriate use of protective barrier equipment by HCWs at all times

210.    Scully C, Greenspan JS. Human Immunodeficiency Virus (HIV) Transmission in Dentistry. J Dent Res 2006; 85(9):794-800.
ABSTRACT: HIV transmission in the health-care setting is of concern. To assess the current position in dentistry, we have reviewed the evidence to November 1, 2005. Transmission is evidently rare in the industrialized nations and can be significantly reduced or prevented by the use of standard infection control measures, appropriate clinical and instrument-handling procedures, and the use of safety equipment and safety needles. We hope that breaches in standard infection control will become vanishingly small. When occupational exposure to HIV is suspected, the application of post-exposure protocols for investigating the incident and protecting those involved from possible HIV infection further reduces the likelihood of HIV disease, and also stress and anxiety

211.    Shah SM, Merchant AT, Dosman JA. Percutaneous injuries among dental professionals in Washington State. BMC Public Health 2006; 6:269.
ABSTRACT: BACKGROUND: Percutaneous exposure incidents facilitate transmission of bloodborne pathogens such as human immunodeficiency virus (HIV), hepatitis C virus (HCV) and hepatitis B virus (HBV). This study was conducted to identify the circumstances and equipment related to percutaneous injuries among dental professionals. METHODS: We used workers' compensation claims submitted to the Department of Labor and Industries State Fund during a 7-year period (1995 through 2001) in Washington State for this study. We used the statement submitted by the injured worker on the workers' compensation claim form to determine the circumstances surrounding the injury including the type of activity and device involved. RESULTS: Of a total of 4,695 accepted State Fund percutaneous injury claims by health care workers (HCWs), 924 (20%) were submitted by dental professionals. Out of 924 percutaneous injuries reported by dental professionals 894 (97%) were among dental health care workers in non-hospital settings, including dentists (66, 7%), dental hygienists (61, 18%) and dental assistants (667, 75%). The majority of those reporting were females (638, 71%). Most (781, 87%) of the injuries involved syringes, dental instruments (77, 9%), and suture needles (23%). A large proportion (90%) of injuries occurred in offices and clinics of dentists, while remainder occurred in offices of clinics and of doctors of medicine (9%), and a few in specialty outpatient facilities (1%). Of the 894 dental health care workers with percutaneous injuries, there was evidence of HBV in 6 persons, HCV in 30 persons, HIV in 3 persons and both HBV and HVC (n = 2) exposure. CONCLUSION: Out of hospital percutaneous injuries are a substantial risk to dental health professionals in Washington State. Improved work practices and safer devices are needed to address this risk

212.    Shepard CW, Simard EP, Finelli L, Fiore AE, Bell BP. Hepatitis B Virus Infection: Epidemiology and Vaccination. Epidemiol Rev 2006.
ABSTRACT: Worldwide, two billion people have been infected with hepatitis B virus (HBV), 360 million have chronic infection, and 600,000 die each year from HBV-related liver disease or hepatocellular carcinoma. This comprehensive review of hepatitis B epidemiology and vaccines focuses on definitive and influential studies and highlights current trends, policies, and directions. HBV can be transmitted vertically, through sexual or household contact, or by unsafe injections, but chronic infections acquired during infancy or childhood account for a disproportionately large share of worldwide morbidity and mortality. Vaccination against HBV infection can be started at birth and provides long-term protection against infection in more than 90% of healthy people. In the 1990s, many industrialized countries and a few less-developed countries implemented universal hepatitis B immunization and experienced measurable reductions in HBV-related disease. For example, in Taiwan, the prevalence of chronic infection in children declined by more than 90%. Many resource-poor nations have recently initiated universal hepatitis B immunization programs with assistance from the Global Alliance for Vaccines and Immunization. Further progress towards the elimination of HBV transmission will require sustainable vaccination programs with improved vaccination coverage, practical methods of measuring the impact of vaccination programs, and targeted vaccination efforts for communities at high risk of infection

213.    Smith DR, Choe MA, Jeong JS, Jeon MY, Chae YR, An GJ. Epidemiology of needlestick and sharps injuries among professional Korean nurses. Journal of Professional Nursing 2006; 22(6):359-366.
ABSTRACT: Although needlestick and sharps injuries (NSI) are known to affect professional nurses at high rates, most studies depend on officially reported data and few have been undertaken in Korea. Thus, we surveyed a large cross-section of nurses from a hospital in Gangneung (response rate, 97.9%). Four hundred thirty-two incidents of NSI were reported by 263 nurses (79.7%) in the previous 12-month period (average, 1.31 events/nurse/year). Syringe needles were the most common devices, affecting 67.3% and comprising 52% of all NSI events. Sixty percent of all NSI events involved contaminated devices. Opening an ampoule or vial was the most common cause (affecting 35.2% of all nurses and accounting for 15.9% of all NSI events). Logistic regression indicated that nurses working in "other" departments were 5.4 times more likely to suffer any NSI (odds ratio [OR] = 5.4; 95% confidence interval [95% CI] = 2.0-15.2; P < .05) and 4.7 times more likely to incur a syringe-needle injury than nurses in intensive care units or inpatient departments (OR = 4.7; 95% CI = 2.0-11.6; P < .05). Younger-than-average nurses (< 27 years) were 4.5 times more likely to suffer NSI (OR = 4.5; 95% CI = 1.7-12.6; P < .05) and 3.1 times more likely to incur a syringe-needle injury (OR = 3.1; 95% CI = 1.4-7.0; P < .05). Working mixed shifts also increased the risk of any NSI (OR = 4.0; 95% CI = 1.7-10.4; P < .05) or syringe-needle NSI (OR = 4.4; 95% CI = 2.0-10.1; P < .05). Overall, our study suggests that NSI are common among Korean hospital nurses and represent a significant occupational burden for this large Asian demographic. Intervention and preventive strategies to help reduce their NSI exposures are urgently required in this country

214.    Smith DR, Wei N, Zhang YJ, Wang RS. Needlestick and sharps injuries among a cross-section of physicians in Mainland China. Am J Ind Med 2006; 49(3):169-174.
ABSTRACT: BACKGROUND: Although needlestick and sharps injuries (NSI) represent a significant occupational hazard for physicians worldwide, their epidemiology has not been previously examined in Mainland China. This study describes the prevalence, distribution, and risk factors for NSI among a cross-section of Chinese physicians. METHODS: Data was obtained by an anonymous, self-reporting survey administered to all 361 physicians at a university teaching hospital, during 2004. RESULTS: Seventy-nine percent of the physicians responded. Among them, 64% had experienced an NSI in the previous 12 months, 50.3% of which involved contaminated devices. By device, 22.8% were caused by hollow-bore syringe needles, 19.1% by suture needles, and 12.1% by scalpel blades. Surgical procedures accounted for 27.9% of all injuries. Only 15.3% of physicians had officially reported their NSI to management, of which 10% went unreported because the individual felt they were not unlucky enough to get a disease. A statistically significant correlation was demonstrated between NSI and working in the intensive care unit (adjusted odds ratio: 5.3, 95% CI: 1.7-23.4). CONCLUSIONS: Although this study suggests that NSI are an important workplace hazard for Chinese physicians, future measures should consider the unique cultural beliefs of Chinese people and its effect on preventive behaviors. The concept of "luck," and its relationship with NSI reporting in particular, may also need to be addressed

215.    Smith DR, Mihashi M, Adachi Y, Nakashima Y, Ishitake T. Epidemiology of needlestick and sharps injuries among nurses in a Japanese teaching hospital. Journal of Hospital Infection 2006; 64(1):44-49.
ABSTRACT: The epidemiology of needlestick and sharps injuries (NSIs) was investigated among a complete cross-section of 1,162 nurses from a large hospital in southern Japan (response rate 74.0%). Forty-six percent had experienced an NSI in the previous year. Most were caused by ampoules or vials, which injured 32.3% of all nurses and accounted for 42.9% of all NSI events. Twenty-two percent of all NSIs involved a device that had been used on a patient prior to the NSI (contaminated device), while the usage status of a further 2.8% of devices was unknown. Logistic regression indicated that nurses younger than 25 years of age were 2.18 times more likely to have sustained a single NSI in the past 12 months [odds ratio (OR) 2.18, 95% confidence intervals (CI) 1.15-4.17] and 2.39 times more likely to have sustained multiple NSIs (OR 2.39, 95% CI 1.08-5.34). Working mixed shifts (rotating day and night, as opposed to day shifts alone) was associated with a 1.67-fold increased risk of sustaining any NSI (OR 1.67, 95% CI 1.01-2.85) and a 2.72 times greater risk of sustaining an NSI from a contaminated device (OR 2.72, 95% CI 1.71-4.44). Nurses who reported significant fatigue after work were 1.87 times more likely to sustain multiple NSIs (OR 1.87, 95% CI 1.13-3.13) and 1.94 times more likely not to report their NSIs (OR 1.94, 95% CI 1.03-3.71). Perceived high mental pressure was associated with a 1.75-fold increased risk of sustaining an NSI from a contaminated device (OR 1.75, 95% CI 1.07-2.88). Nurses who reported suboptimal staffing levels in their wards were 2.21 times more likely not to report any NSIs they sustained in the previous year (OR 2.21, 95% CI 1.06-4.89). Overall, this study suggests that NSIs represent a complex and multi-faceted problem for Japanese nurses. Intervention strategies should consider the emerging complicity of psychosocial factors on NSI among hospital staff in Japan, as elsewhere

216.    Smith DR, Smyth W, Leggat PA, Wang RS. Needlestick and sharps injuries among nurses in a tropical Australian hospital. Int J Nurs Pract 2006; 12(2):71-77.
ABSTRACT: Although needlestick and sharps injuries (NSI) represent a major hazard in nursing practice, most studies rely on officially reported data and none have yet been undertaken in tropical environments. Therefore, we conducted a cross-sectional NSI survey targeting all nurses within a tropical Australian hospital, regardless of whether they had experienced an NSI or not. Our overall response rate was 76.7%. A total of 39 nurses reported 43 NSI events in the previous 12 months. The most common causative device was a normal syringe needle, followed by insulin syringe needles, i.v. needles or kits and blood collection needles. Half of the nurses' NSI events occurred beside the patient's bed: drawing up medication was the most common reason. Nurses working in the maternity/neonatal wards were only 0.3 times as likely to have experienced an NSI as their counterparts in the medical or surgical wards. Overall, our study has shown that NSI events represent an important workplace issue for tropical Australian nurses. Their actual rate might also be higher than official reports suggest

217.    Sohn JW, Kim BG, Kim SH, Han C. Mental health of healthcare workers who experience needlestick and sharps injuries. Journal of Occupational Health 2006; 48(6):474-479.
ABSTRACT: Healthcare workers (HCWs) are exposed daily to the risk of injury by needlesticks and other medical instruments. However, the psychiatric impacts of such injuries have not been evaluated. The aim of this study was to evaluate the mental health status of HCWs with experiences of needlestick and sharps injuries. A cross-sectional written survey was performed. The psychological symptoms before injury and current status were measured using the Beck Depression Inventory (BDI), Hamilton Anxiety Scale (HAM-A) and Perceived Stress Scale (PSS). The proportions of HCWs with and without needlestick and sharps injuries were 71.1% (n=263) and 28.9% (n=107), respectively. HAM-A and BDI scores were significantly higher among HCWs with injury experiences (p<0.01). HCWs with injury experiences exhibited higher PSS and BDI scores after the injury and higher levels of anxiety and depression. Particular attention should be directed towards the psychological consequences of needlestick and sharps injuries in HCWs

218.    St Lawrence JS, Klaskala W, Kankasa C, West JT, Mitchell CD, Wood C. Factors associated with HIV prevalence in a pre-partum cohort of Zambian women. Int J STD AIDS 2006; 17(9):607-613.
ABSTRACT: An ongoing study of mother-to-child human herpes virus-8 (HHV-8) transmission in Zambian women (n = 3160) allowed us to examine the association of medical injections with HIV serostatus while simultaneously accounting for other factors known to be correlated with HIV prevalence. Multi-method data collection included structured interviews, medical record ABSTRACTion, clinical examinations, and biological measures. Medically administered intramuscular or intravenous injections in the past five years (but not blood transfusions) were overwhelmingly correlated with HIV prevalence, exceeding the contribution of sexual behaviours in a multivariable logistic regression. Statistically significant associations with HIV also were found for some demographic variables, sexual behaviours, alcohol use, and sexually transmitted diseases (STD). The results confirmed that iatrogenic needle exposure, sexual behaviour, demographic factors, substance use, and STD history are all implicated in Zambian women's HIV+ status. However, the disproportionate association of medical injection history with HIV highlights the need to investigate further and prospectively the role of health-care injection in sub-Saharan Africa's HIV epidemic

219.    Sterling TR, Haas DW. Transmission of Mycobacterium tuberculosis from health care workers. New England Journal of Medicine 2006; 355(2):118-121.
ABSTRACT: The Centers for Disease Control and Prevention (CDC) recently reported the transmission of Mycobacterium tuberculosis from a health care worker to patients in New York City.1 Several aspects of the episode were notable: the health care worker was foreign-born; latent tuberculosis infection had previously been diagnosed by tuberculin skin testing, but the health care worker had declined treatment; and after active disease developed in the health care worker, 1500 persons were exposed, which necessitated a large-scale contact investigation to determine the extent of transmission and prevent further spread.

220.    Stringer B, Haines T, Goldsmith CH et al. Perioperative use of the hands-free technique: a semistructured interview study. AORN Journal 2006; 84(2):233-235.
ABSTRACT: OCCUPATIONALLY CONTRACTED bloodborne infections are preventable, but the use of many protective measures remains limited. THERE IS GROWING EVIDENCE that the use of the hands-free technique (HFT) to pass sharp items during surgical procedures is effective in protecting against sharps injury and bloody contamination. RESEARCHERS CONDUCTED in-depth telephone interviews to explore 20 health care providers' knowledge and use of the HFT. MOST OF THE INTERVIEWEES did not regularly use the HFT, and some were resistant to its use

221.    Stringer B, Haines T. Hands-free technique: preventing occupational exposure during surgery. Journal of Perioperative Practice 2006; 16(10):495-500.
ABSTRACT: Occupational exposure to blood borne pathogens has led to HBV, HCV and HIV infections among surgeons, nurses and other operating room (OR) personnel and, to a lesser degree, patients (Ross et al 2000, The incident investigation teams and others 1997). Of seven OR studies in which an observer or circulating nurse recorded exposures, there was a percuataneous injury in 1.7-15% of all surgeries, and a mucocutaneous contamination in 6.2-50% of all surgeries. (Gerberding et al 1990, Panlilio et al 1991, Popejoy & Fry 1991, Quebbeman et al 1991, Tokars et al 1992, Lynch & White 1993, Stringer, Infante-Rivard & Hanley 2002). Surgeons and residents usually sustained the greatest number of percutaneous and other exposures during surgery. [References: 26]

222.    Suzuki R, Kimura S, Shintani Y et al. [The efficacy of safety winged steel needles on needlestick injuries]. [Japanese]. Kansenshogaku Zasshi - Journal of the Japanese Association for Infectious Diseases 2006; 80(1):39-45.
ABSTRACT: Safety winged steel needles were introduced at the University of Tokyo Hospital in January 2001. We studied their effect in needlestick injuries. A total of 952 'needlestick and sharp-object injuries were reported. From January 1999 to December 2004, Cases of injury with winged steel needles decreased dramatically soon after safety devices were introduced, from 19.8% in Apr.-Dec.2000 to 6.7% in 2001 and 5.5% in 2002 (p < .01). They began to increase, however, in July 2002, decreased again after medical staff members mere given lectures and notices by e-mail. Due to the introduction of safety devices, cases classified as a "while recapping a used needle" and "when puncturing rubber stoppers" decreased. Among 17 injuries with safety winged steel needles, the most common cases were "safety mechanism not activated". We estimated that 76.5% of cases with safety winged steel needles could be prevented if they were used properly. In conclusion, the introduction of safety winged steel needles effectively reduced cases of injury with such needles. It is thus important to regularly remind hospital staff of safety device techniques and information reduce the such injuries

223.    Tabak N, Shiaabana AM, Shasha S. The health beliefs of hospital staff and the reporting of needlestick injury. J Clin Nurs 2006; 15(10):1228-1239.
ABSTRACT: AIM: The aim of this study is to examine the connection between the health beliefs of hospital staff (doctors, nurses and auxiliary staff) and their failure to report needlestick injuries. BACKGROUND: Needlestick injury to hospital staff is quite frequent and can result in infections and disease, but staff frequently do not report the injury despite their awareness of the risk of blood-borne pathogens. METHODS: Five questionnaires were constructed based on three existing research tools and were tested for validity and reliability. Two hundred and forty questionnaires were distributed to eight randomly chosen departments of a single Israeli hospital. Seventy-six percent of the questionnaires were anonymously completed and returned. RESULTS: Nurses had the highest rate of needlestick injury, followed by auxiliary staff and doctors. Auxiliary staff showed the highest rate of compliance with the duty to report such injuries, while doctors showed the lowest. Perceived severity of contractable disease, the perceived efficacy of reporting injuries and overall motivation to maintain health were the best predictors of reporting compliance. Non-compliers emphasized the negative aspects of reporting the injuries, primarily that it took up too much time. CONCLUSIONS: The solution to non-compliance with the duty to report must be a targeted investment in training and education. Relevance to clinical practice. Finding the reasons for compliance and non-compliance with the duty to report needlestick injuries will help in designing educational programmes for hospital staff and in determining a strategy for improving health behaviour

224.    Tao XG, Bernacki EJ, Jankosky C, Means C. An assessment of universal versus risk-based hepatitis C virus testing of source patients postexposure to blood and body fluids among healthcare workers. Journal of Occupational & Environmental Medicine 2006; 48(5):470-477.
ABSTRACT: OBJECTIVE: The objective of this study was to assess the impact of universal versus risk-based hepatitis C (HCV) testing of source patients' (SPs) postexposure to blood and body fluids on the HCV exposure rates among healthcare workers. METHODS: Exposure and test result information between 1993 and 2004 was ABSTRACTed from the Johns Hopkins Bloodborne Pathogen Database. A Poisson regression model estimating HCV infection among underlying SPs based on partial testing was developed and applied. RESULTS: After adjusting for the effect of partial testing of SPs, the estimated underlying prevalence of HCV-positive SPs increased slightly during the study period, from 11.9% to 15.1%, but the trend was not statistically significant. Yield curve of HCV-positive SPs rose quickly when SPs' testing rates were low but became flat when SPs' testing rates were high. CONCLUSION: Reliance on HCV risk factors to screen SPs resulted in an underestimation of the prevalence of HCV in SPs before 1997 when the testing rates were between 15.4% and 25.6%. When SPs' testing rates were above 65%, our model predicted no additional yield of HCV-positive SPs

225.    Tarantola A, Golliot F, L'Heriteau F et al. Assessment of preventive measures for accidental blood exposure in operating theaters: A survey of 20 hospitals in Northern France. Am J Infect Control 2006; 34(6):376-382.
ABSTRACT: BACKGROUND: Accidental exposures to blood of body fluids (ABE) expose health care workers (HCW) to the risk of occupational infection. OBJECTIVES: Our aim was to assess the prevention equipment available in the operating theater (OT) with reference to guidelines or recommendations and its use by the staff in that OT on that day and past history of ABE. METHODS: Correspondents of the Centre de Coordination de la Lutte contre les Infections Nosocomiales (CCLIN) Paris-Nord ABE Surveillance Taskforce carried out an observational multicenter survey in 20 volunteer French hospitals. RESULTS: In total, 260 operating staff (including 151 surgeons) were investigated. Forty-nine of the 260 (18.8%) staff said they double-gloved for all patients and procedures, changing gloves hourly. Blunt-tipped suture needles were available in 49.1% of OT; 42 of 76 (55.3%) of the surgeons in these OT said they never used them. Overall, 60% and 64% of surgeons had never self-tested for HIV and hepatitis C virus (HCV), respectively. Fifty-five surgeons said they had sustained a total of 96 needlestick injuries during the month preceding the survey. Ten of these surgeons had notified of 1 needlestick injury each to the occupational health department of their hospital (notification rate, 10.4%). CONCLUSION: The occurrence of needlestick injury remained high in operating personnel in France in 2000. Although hospitals may improve access to protective devices, operating staff mindful of safety in the OT should increase their use of available devices, their knowledge of their own serostatus, and their ABE notification rate to guide well-targeted prevention efforts

226.    Tarantola A, Abiteboul D, Rachline A. Infection risks following accidental exposure to blood or body fluids in health care workers: a review of pathogens transmitted in published cases. Am J Infect Control 2006; 34(6):367-375.
ABSTRACT: Hospital staff and all other human or veterinary health care workers, including laboratory, research, emergency service, or cleaning personnel are exposed to the risk of occupational infection following accidental exposure to blood or body fluids (BBF) contaminated with a virus, a bacteria, a parasite, or a yeast. The human immunodeficiency virus (HIV) or those of hepatitis B (HBV) or C (HCV) account for most of this risk in France and worldwide. Many other pathogens, however, have been responsible for occupational infections in health care workers following exposure to BBF, some with unfavorable prognosis. In developed countries, a growing number of workers are referred to clinicians responsible for the evaluation of occupational infection risks following accidental exposure. Although their principal task remains the evaluation of the risks of HIV, HBV, or HCV transmission and the possible usefulness of postexposure prophylaxis, these experts are also responsible for evaluating risks of occupational infection with other emergent or more rare pathogens and their possible timely prevention. The determinants of the risks of infection and the characteristics of described cases are discussed in this article

227.    Taylor DL, III. Bloodborne pathogen exposure in the OR--what research has taught us and where we need to go. [Review] [29 refs]. AORN Journal 2006; 83(4):834-838.
ABSTRACT: Contracting a disease from bloodborne pathogens has been identified as an occupational hazard for perioperative personnel for more than two decades. Perioperative staff members are particularly vulnerable to percutaneous exposure. Despite known hazards, research has shown that perioperative staff members continue to take risks by not consistently complying with standard precautions and not reporting all percutaneous injuries. Health care workers (HCWs) and their employers need to work together to ensure that workplaces are safe. This article discusses mechanisms of bloodborne pathogen transmission, compliance with standard guidelines, and the social and economic costs of contracting a bloodborne illness. Steps to ensure that HCWs are protected also are outlined. [References: 29]

228.    Tuma S, Sepkowitz KA. Efficacy of safety-engineered device implementation in the prevention of percutaneous injuries: a review of published studies. Clinical Infectious Diseases 2006; 42(8):1159-1170.
ABSTRACT: Nearly 6 years have passed since the Needlestick Safety and Prevention Act of 2000 was signed into law. We reviewed studies published since 1995 that evaluated the effect of safety-engineered device implementation on rates of percutaneous injury (PI) among health care workers. Criteria for inclusion of studies in the review were as follows: the intervention used to reduce PIs was a needleless system or a device with engineered sharps-injury protection, the outcome measurements included a PI rate, the intervention was evaluated in a defined population with clear comparison groups in clinical settings, and outcomes and denominators used for rate calculations were objectively measured using consistent methodology. All 17 studies reported substantial decreases in device-associated or overall PI rates after device implementation (range of reduction, 22%-100%). The majority of studies (n=12) were uncontrolled before-after trials with limited ability to control for confounding variables. In addition, implementation of safety-engineered devices was often accompanied by other interventions, and direct measurement of outcomes was not performed. Nevertheless, safety-engineered devices are an important component in PI prevention

229.    Utkan A, Dayican A, Toyran A, Tumoz MA. [Seroprevalences of hepatitis B, hepatitis C, and HIV in patients admitted to orthopedic and traumatology department]. [Turkish]. Acta Orthopaedica et Traumatologica Turcica 2006; 40(5):367-370.
ABSTRACT: OBJECTIVES: Orthopedic surgeons are at a higher occupational risk for blood-borne infections because of frequent handling of sharp instruments and bone fragments. We investigated the seroprevalences of hepatitis B, hepatitis C, and human immunodeficiency virus (HIV) among patients treated at orthopedic and traumatology department. METHODS: Data on age, sex, diagnoses, and the seroprevalences of HBsAg, anti-HCV and anti-HIV were reviewed in 1,040 patients hospitalized between September 2003 and December 2004. The patients were divided into two groups as orthopedics (n=646; mean age 37.8 years) or trauma (n=394; mean age 38.3 years) according to the initial cause of presentation. The results were compared with those of 28,642 blood donations during the same period. RESULTS: HBsAg positivity was similar in the patients (2.3%) and the controls (2.1%). HBsAg was detected in 16 patients (2.5%) in the orthopedics group and eight patients (2%) in the trauma group (p>0.05), three of whom were younger than one year. Similarly, the prevalences of anti-HCV antibodies were similar in the patient (0.6%) and control (0.3%) groups. Four patients (0.6%) in the orthopedics group and two patients (0.5%) in the trauma group were positive for anti-HCV (p>0.05), and all had a past history of operations. Anti-HIV positivity was not detected in the patient group, whereas it was 0.2% in the control group. CONCLUSION: The similarities between patients admitted to orthopedic and traumatology department and blood donors in the prevalences of HBsAg, and anti-HCV and anti-HIV antibodies suggest that data obtained from blood banks can be used for risk calculations

230.    Utomi IL. Occupational exposures and infection control among students in Nigerian dental schools. Odonto-Stomatologie Tropicale 2006; 29(116):35-40.
ABSTRACT: OBJECTIVE: To assess the incidence of occupational exposures to body fluids and infection control practices among students in Nigerian dental schools. MATERIALS AND METHODS: A self-administered questionnaire survey of 112 students from three Nigerian dental schools. RESULTS: 57 (50.9%) of the students had experienced one or more occupational exposures in the previous six months. There was no statistically significant association between year group and reported number of exposures (p > 0,05). There was also no statistically significant association between sex and reported number of exposures (p > 0.05). 50.7% of the exposures were percutaneous injuries, 26.1% splatter of saliva and 23.2% splatter of aerosol. Percutaneous injuries were most frequently caused by scalers (42.9%) and needlesticks (37.1%) Most incidents occurred during scaling (37.7%),use of dental handpiece (21.7%) and cleaning of instruments (18.8%). 96.4% of the exposures were not reported. Only 36.6% of the students were immunized against Hepatitis B. None of those immunized had been post-screened for seroconversion. The routine use of gloves, masks and protective eyewear was reported by 87.5%, 65.5% and 17% of students respectively. CONCLUSIONS: This study indicates a high rate of exposure to body fluids and low compliance with infection control guidelines. There is a need for interventions to improve safe work practices, hepatitis B vaccination, HBV post-immunization serology and use of protective barriers. Also appropriate policies and procedures are needed for reporting and managing exposures

231.    van Gemert-Pijnen J, Hendrix MG, Van der PJ, Schellens PJ. Effectiveness of protocols for preventing occupational exposure to blood and body fluids in Dutch hospitals. J Hosp Infect 2006; 62(2):166-173.
ABSTRACT: Compliance of different healthcare workers (HCWs) (nurses, physicians, laboratory technicians and cleaners) with protocols to prevent exposure to blood and body fluids (BBF) was studied. Questionnaires were used to assess perception of risks, familiarity with protocols, motivation and actual behaviour. Performance of the protocols in practice was also tested. The practical test provided more reliable results than the questionnaire. HCWs overestimated their knowledge and skills, and compliance was influenced by risk perception. HCWs encountered problems with comprehension, acceptability and applicability of protocols, especially for post-exposure precautions. Protocols are not tailored to the differences in knowledge, risk perception and practical needs of different professional groups, probably because HCWs have rarely been involved in writing them and they are governed more by legal considerations than applicability. Most HCWs experienced a lack of organizational support to aid compliance. To improve compliance, we recommend information and training on risk management and individual responsibilities regarding the safety of coworkers and patients, participation of HCWs in protocol development, and support of management to avoid reversion to previous habitual behaviour

232.    van Wijk PT, Pelk-Jongen M, de BE, Voss A, Wijkmans C, Schneeberger PM. Differences between hospital- and community-acquired blood exposure incidents revealed by a regional expert counseling center. Infection 2006; 34(1):17-21.
ABSTRACT: OBJECTIVE: One year (2003) regional analysis of all blood exposure incidents from hospitals as well as from the community. DESIGN: Establishment of an easily accessible regional expert counseling center, operating 24 h a day, for all accidental blood exposures. Tasks of the center were to register incoming calls, to inform and counsel the victim, to assess the risk of the incident, and to provide a plan of further actions, including prophylactic measures. SETTING: A Dutch region (Northeast Brabant) with 500,000 inhabitants and two major hospitals (1,786 beds). RESULTS: A total of 454 incidents (1.2 per day) were recorded. Only half of the incidents occurred in the hospital setting (n = 234), whereas the others (n = 220) took place in the community setting. Nearly all (95%, n = 432) incidents occurred during work, and most of them (84%, n = 385) were related to health care activities. In the hospital setting injuries occurred with physicians (13%), nursing staff (45%), operating room (OR) staff (13%), ancillary (18%), others (10%). In the community setting, incidents took place among healthcare workers (48%), detention and police officers (10%), civilians (10%), general practitioners/dentists and their staff (8%), cleaning staff (4%) and work-related incidents not falling into any of the above categories (7%). More low risk incidents took place outside the hospital (87% vs. 68% in hospital), while high-risk incidents predominantly occurred within the hospital setting (23% vs. 6%). The hepatitis-B immunization rate was significantly lower in victims from the community than in those working in hospitals (38% vs. 96%). Reports from incidents in the community setting were delayed. CONCLUSIONS: Incidents that expose individuals to blood-borne pathogens occur equally frequent in the hospital and non-hospital (community) setting. Therefore, a regional expert counseling center, accessible around-the-clock, for all types of blood-exposure incidents is needed. Blood-exposure prevention programs should aim at a reduction of high-risk incidents within hospitals, and at increasing the awareness for vaccination and early reporting within the community setting

233.    van Wijk PT, Pelk-Jongen M, Wijkmans C, Voss A, Schneeberger PM. Quality control for handling of accidental blood exposures. J Hosp Infect 2006; 63(3):268-274.
ABSTRACT: A regional counselling service was established to handle all accidental blood exposures using a standardized protocol. Levels of risk were assessed using an algorithm. Accidents that posed a risk for the transmission of hepatitis B (HBV), hepatitis C (HCV) and human immunodeficiency virus (HIV) were classified as 'high risk', whereas accidents that posed a risk for HBV alone were classified as 'low risk'. Medical interventions were implemented according to the level of risk. During a one-year period, all accidents were registered and analysed for adherence to the standard protocol. In 2003, the centre handled 454 incidents. Of these, 36 (7.9%) incidents were assessed as no risk, 329 (72.5%) were assessed as low risk, and 67 (14.8%) were assessed as high risk. Due to incomplete registration, 22 (4.8%) incidents could not be analysed further. In total, 36% of the incidents with risk for HBV transmission and 40% of the incidents with risk for HCV and HIV transmission were not handled according to the proposed protocol. Breaches consisted of over-reaction (25/396) as well as insufficient response (123/396). Potentially inadequate treatment occurred for HIV postexposure prophylaxis in 12 of 63 incidents. Incomplete follow-up for HCV occurred in 11 of 63 incidents, and lack of HBV immunoglobulin administration occurred in five of 396 incidents, including three high-risk incidents. In 21 of 396 low-risk exposures, the breaches in protocol resulted from late reporting. It remains difficult to achieve an acceptable level of standardized care when using standard operational procedures. Documentation and evaluation of flaws are essential to improve the system

234.    Visser L. Toronto hospital reduces sharps injuries by 80%, eliminates blood collection injuries. A case study: Toronto East General Hospital pioneers healthcare worker safety. Healthc Q 2006; 9(1):68-70, 4.
ABSTRACT: Needlestick and other sharps injuries are a key Canadian public health issue, affecting 70,000 people per year and costing some dollar 140 million. A safety program at Toronto East General Hospital--focusing on blood collection and patient injection--achieved an 80% reduction in injuries within one year (from 41 in 2003 to eight in 2004), with blood collection injuries eliminated entirely

235.    Vos D, Gotz HM, Richardus JH. Needlestick injury and accidental exposure to blood: the need for improving the hepatitis B vaccination grade among health care workers outside the hospital. Am J Infect Control 2006; 34(9):610-612.
ABSTRACT: To describe the characteristics of needlestick injuries occurring to health care workers outside the hospital, a new case report form was implemented and analyzed after 12 months. A total of 144 incidents were reported. Of the needlestick injuries in nursing assistants, 84% involved an insulin needle or pen. Thirty-five percent of all health care workers and 47% of the nursing assistants were not vaccinated against hepatitis B. Hepatitis B vaccination grade in health care workers outside the hospital should be improved, in particular among nursing assistants

236.    Wanchu A, Singh S, Bambery P, Varma S. Possible occupationally acquired HIV infection in two Indian healthcare workers. MedGenMed 2006; 8(2):56.

237.    Wolf BL, Marks A, Fahrenholz JM. Accidental needle sticks, the Occupational Safety and Health Administration, and the fallacy of public policy. Ann Allergy Asthma Immunol 2006; 97(1):52-54.
ABSTRACT: BACKGROUND: Current Occupational Safety and Health Administration (OSHA) guidelines mandate the use of safety needles when allergy injections are given. Safety needles for intradermal testing remain optional. Whether safety needles reduce the number of accidental needle sticks (ANSs) in the outpatient setting has yet to be proven. OBJECTIVE: To determine the rate of ANSs with new (safety) needles vs old needles used in allergy immunotherapy and intradermal testing. METHODS: Allergy practices from 22 states were surveyed by e-mail. RESULTS: Seventy practices (28%) responded to the survey. Twice as many ANSs occurred in practices giving immunotherapy when using new needles vs old needles (P < .01). The rate of ANSs was roughly the same for intradermal testing with new needles vs old needles. CONCLUSIONS: These findings further question whether OSHA's guidelines for safety needle use in outpatient practice need revision and if allergy practices might be excluded from the requirement to use safety needles

238.    Yazdanpanah Y, De Carli G, Migueres B et al. [Risk factors for hepatitis C virus transmission to Health Care Workers after occupational exposure: a European case-control study]. Rev Epidemiol Sante Publique 2006; 54:Spec-1S31.
ABSTRACT: BACKGROUND: Factors that influence the risk for HCV infection after occupational exposure to hepatitis C virus (HCV) have not yet been determined. The objective of this study was to assess potential risk factors for Hepatitis C seroconversion after occupational exposure to HCV. METHODS: We conducted a European matched case-control study from 01/01/1991 through 31/12/ 2002. Cases were Health Care Workers (HCWs) who were HCV seronegative at the time of exposure, sustained a documented exposure to HCV, and present documented HCV seroconversion temporally associated with the exposure. Controls-HCWs had a documented exposure to HCV, were HCV seronegative at the time of exposure, and remained so at least 6 months later. Controls were matched to cases for the center and the time period of the exposure occurrence. RESULTS: 60 cases and 204 controls were included. All cases were exposed to HCV-infected materials through percutaneous injuries. Those for whom information was available (61.6%) were exposed to viremic source patients. Multivariate conditional logistic regression analysis, in which HCV viral load was not introduced because of missing values, identified needle placed in the source patient's vein or artery (Odds Ratio [OR]=100.1; 95% Confidence Interval [CI]=7.3-1365.7), deep injury (OR=155.2; 95%CI=7.1-3417.2), and HCW's gender (M vs. F: OR=3.1; 95%CI=1.0-10.0) as risk factors for HCV infection. In univariate unmatched analysis the risk of HCV transmission was increased 11-fold (C195%=1.1-114.1) in HCWs exposed to sources with a viral load>6 log10 copies/mL when compared to sources with a HCV viral load<4 log10 copies/mL. CONCLUSION: The risk of HCV transmission after percutaneous exposure increases with a larger volume of blood, and, a higher titer of HCV in the source patient's blood. The role of HCW's gender need to be further investigated. The results of this study have important implications for counselling and follow-up of HCWs after exposure

239.    Zafar A. Blood and body fluid exposure and risk to health care workers. JPMA - Journal of the Pakistan Medical Association 2006; 56(10):428-429.
ABSTRACT: Blood and body fluid (BBF) exposure to health care workers (HCWs) and the infectious complications associated with it, is a global issue. It affects all categories of staff including clinicians, dental professionals and students both medical and nursing, laboratory workers, paramedics, domestics, porters, hospital volunteers and administrative staff. Exposure includes splash of BBF to the eyes, nasal and oral cavities, or contact with damaged skin and needle stick injuries.

240.    Nadelstichverletzungen: Der bagatellisierte „Massenunfall" [Needlestick injuries: the trivialized mass accident]. Deutsches Arzteblatt 2005; 102:110-114.
ABSTRACT: Injuries of the medical personnel with sharp objects are among the most frequent working accidents; in at least every second, the offensive objects contaminated through patient blood (1).  Independently of, whether such sting injuries, cut injuries or scraper injuries the skin through needles, knife or similar objects causes became (2), speaks one for reasons the Praktikabilität usually about needle sting injuries (NSTV).  Alone at the occupation union for health service and welfare cultivated (BGW) are in 2002,170 hepatitis-B-, 254 hepatitis-C- and nine HIV-Infektionen1 after NSTV indicated become.  In the USA is assumed, emerge that annually 5,100 occupation contingent HBV-infections at the medical personnel (6).

241.    How Safety Became the Norm, Not Needlesticks: Why not make 'airbags' for needles? Hospital Employee Health 2005; 24(12):155-157.
ABSTRACT:      Janine Jagger was working onintegrating airbags in cars when her colleagues at the University of Virginia told her about another safety problem: Health care workers stuck with needles were at risk of contracting HIV/AIDS, as well as other bloodborne diseases.
     To her, the answer was obvious.  Create the equivalent of an airbag for a needle.

242.    Surveillance of significant occupational exposure to bloodborne viruses in healthcare workers: 1 July 1996 to 30 June 2004. Communicable Disease Report 2005; 15(4):3-4.
ABSTRACT: The Health Protection Agency's Centre for Infections (CFI) has this week published Eye of the Needle, the latest report from the surveillance of significant occupational exposure to bloodborne viruses (BBVs) in healthcare workers (HCWs) (1). This report includes significant occupational exposure incidents reported to the CFI between 1 July 1996 and 30 June 2004 from reporting centres. There are currently 150 reporting centres scattered throughout England, Wales, and Northern Ireland.

243.    Nadelstichverletzung ist kein Bagatellunfall [A needlestick injury is not a trivial accident]. Arzte Zeitung 2005.
ABSTRACT: Pflegekräfte, Arzthelferinnen und Ärzte haben ein erhöhtes Risiko, sich durch Nadelstichverletzungen mit Hepatitis oder HIV zu infizieren. Dagegen können sich Arbeitgeber und Mitarbeiter schützen, in dem sie Spritzen, Kanülen und Skalpelle mit Schutzvorrichtungen gegen solche Verletzungen benutzen.
[Care powers, physician helper and physicians have an increased risk to infect itself through needle sting injuries with hepatitis or HIV.  On the other hand employer and colleague can protect themselves, in whom they use syringes, cannulae and scalpel with protection devices against such injuries]

244.    Anonymous. OR becomes last frontier for move to sharps safety. Hospital Employee Health 2005; 24(12):149-155.
ABSTRACT: ACS endorses blunt needles, spurring change.  American operating rooms may finally be ready to move toward sharps safety.
  The American College of Surgeons (ACS) has endorsed the use of blunt suture needles and is poised to begin an educational push to reduce one of the most persistent remaining causes of sharps injuries.  While sharps injuries have declined overall by about one-third, suturing injuries have remained stable.

245.    Association of periOperative Registered Nurses. AORN guidance statement: sharps injury prevention in the perioperative setting. AORN Journal 2005; 81(3):662-666.
ABSTRACT: Occupational exposure to bloodborne pathogens via percutaneous injuries is one of the most serious dangers perioperative team members face on a daily basis. The risk of sustaining a percutaneous injury can be decreased through employee education, clear communication, device engineering, and focused work practice controls. Risk reduction strategies should include specific practices aimed at reducing the unique risks of percutaneous injuries encountered in the perioperative environment. AORN recognizes the various settings in which perioperative RNs practice, and the suggested risk reduction strategies in this guidance statement are intended to be adaptable to any setting where surgical or other invasive procedures are performed

246.    Azap A, Ergonul O, Memikolu KO et al. Occupational exposure to blood and body fluids among health care workers in Ankara, Turkey. Am J Infect Control 2005; 33(1):48-52.
ABSTRACT: BACKGROUND: The risk of occupational acquisition of bloodborne pathogens via exposure to blood and body fluids is a serious problem for health care workers in Turkey. Because there are no systematic recording programs in Turkey, national data concerning frequency of exposures are not readily available. OBJECTIVE: To determine the risk factors of exposure to blood and body fluids among health care workers (HCWs). METHODS: This study was conducted in the hospitals of Ankara University School of Medicine. A structured survey form was administered by person-to-person interview. RESULTS: The study included 988 HCWs: 500 nurses (51%), 212 residents (21%), 152 nurse assistants (15%), and others (13%). Six hundred thirty-four (64%) of the HCWs had been exposed to blood and body fluids at least once in their professional life (0.85 exposure per person-year). The most frequent cause of the sharps injuries was recapping the needle (45%). Of the injured HCWs, 60 (28%) were not using any personal protective equipment, and 144 (67%) did not seek any medical advice for injury. CONCLUSIONS: Systematic control measures, including an effective and goal-oriented education program targeting HCWs, prospective record keeping, and instillation of a special unit for the health of HCWs should be implemented in the hospital setting

247.    Beekmann SE, Henderson DK. Protection of healthcare workers from bloodborne pathogens. [Review] [50 refs]. Current Opinion in Infectious Diseases 2005; 18(4):331-336.
ABSTRACT: PURPOSE OF REVIEW: For decades, healthcare workers have been known to be at risk from acquiring a variety of bloodborne pathogen infections as a result of occupational exposure. Primary prevention of exposures, as recommended by universal precautions guidelines, remains the cornerstone of protecting healthcare workers. Nonetheless, a substantial number of parenteral exposures continue to occur. Updated developments are summarized here, and recommendations for the protection of healthcare workers from bloodborne pathogens are provided. RECENT FINDINGS: The predominant evidence suggests that total percutaneous injuries have decreased over the last decade. Thoughtful adherence to universal precautions remains the primary means of preventing occupational exposures and thus of reducing occupational risk of infection with bloodborne pathogens. A number of studies have provided additional evidence for the efficacy of safety devices in reducing specific subsets of injuries when combined with education and administrative interventions. Barriers to and positive predictors of universal precautions compliance have been identified. Postexposure prophylaxis remains the second line of defense; several authorities have now recommended three antiretroviral agents in this setting. SUMMARY: In summary, almost two decades of experience with universal/standard precautions has resulted in a decrease in parenteral injuries, but much work remains to be done. Vaccines, effective infection control procedures, safer procedures, and safer devices will all be necessary, along with a better understanding of factors that influence healthcare worker behaviors that result in injury. In addition, a number of issues relating to the postexposure management of occupational exposures with bloodborne pathogens need to be better understood. [References: 50]

248.    Berguer R, Heller PJ. Strategies for preventing sharps injuries in the operating room. Surgical Clinics of North America 2005; 85(6):1299-1305.
ABSTRACT: With the discovery of AIDS and HIV, the medical community began to widely recognize the dangers of serious illnesses spread-ing through contact with contaminated blood and body fluids. In response, the Centers for Disease Control and other groups have developed guidelines for the operating room to prevent the spread of infection from, for example, accidental needle sticks. Unfortunately, those guidelines are not always strictly followed. This article reviews studies that have examined precautionary practices, including such practices as double gloving, the use of blunt suture needles, and the use of neutral zones for passing sharps. The article also provides related sources for further information. [References: 42]

249.     Proceedings of the National Sharps Injury Prevention Meeting. 05 Sep 12; 2005.
ABSTRACT: Occupational exposures to bloodborne pathogens as a result of injuries from needles and other sharp objects are an important public health concern. It is estimated that hospital-based healthcare personnel sustain 385,000 sharps injuries annually in the United States. Numerous risk factors and prevention strategies have been identified and implemented in order to reduce sharps injuries in healthcare settings. One notable prevention milestone was the passage of the Needlestick Safety and Prevention Act in 2001. In response to this Act, OSHA revised the Bloodborne Pathogens Standard, 29 CFR 1910.1030. The revised standard clarifies the need for employers to select safer needle devices and to involve frontline employees in identifying and choosing these devices. The updated Standard also requires employers to maintain a log of injuries from contaminated sharps.

The U.S. Centers for Disease Control and Prevention (CDC) convened a National Sharps Injury Prevention Meeting on September 12, 2005, in Atlanta, Georgia. The purpose of this meeting was to review sharps injury prevention efforts (particularly since the passage of the Needlestick Safety and Prevention Act in 2001); identify gaps in prevention efforts; and assist CDC in creating a national action plan for eliminating sharps injuries in the United States. Nearly forty representatives from federal and state agencies, healthcare professional associations, healthcare facilities, medical device manufacturers, and other key stakeholder groups participated in the meeting. The meeting was funded by the CDC Foundation through an unrestricted education grant from the Safety Institute, Premier Inc.

250.    Cervini P, Bell C. Brief report: needlestick injury and inadequate post-exposure practice in medical students. Journal of General Internal Medicine 2005; 20(5):419-421.
ABSTRACT: BACKGROUND: Medical students are at a particularly high risk for needlestick injury and its consequences because of their relative inexperience and lack of disability insurance. OBJECTIVE: To determine the risk of needlestick injury and the use of post-exposure prophylaxis among medical students. DESIGN: Internet-based survey. PARTICIPANTS: The 2003 graduating medical school class at the University of Toronto. MEASUREMENTS: Number of needlestick injuries, circumstances surrounding those incidents, and post-exposure actions. RESULTS: The response rate was 88% (157/178). Over one third (55/157) of respondents suffered at least 1 needlestick injury. In more than half the high-risk injuries, the students continued working and did not seek medical advice. Six students who suffered a needlestick injury began prophylactic human immunodeficiency virus medications. Of those students who suffered an injury, 15% had purchased disability insurance prior to the incident. CONCLUSIONS: Poor use of post-exposure procedures and a lack of disability insurance leave medical students at high risk for career and life-altering consequences from a needlestick injury

251.    Cervini P, Bell C. Brief report: needlestick injury and inadequate post-exposure practice in medical students. J Gen Intern Med 2005; 20(5):419-421.
ABSTRACT: BACKGROUND: Medical students are at a particularly high risk for needlestick injury and its consequences because of their relative inexperience and lack of disability insurance. OBJECTIVE: To determine the risk of needlestick injury and the use of post-exposure prophylaxis among medical students. DESIGN: Internet-based survey. PARTICIPANTS: The 2003 graduating medical school class at the University of Toronto. MEASUREMENTS: Number of needlestick injuries, circumstances surrounding those incidents, and post-exposure actions. RESULTS: The response rate was 88% (157/178). Over one third (55/157) of respondents suffered at least 1 needlestick injury. In more than half the high-risk injuries, the students continued working and did not seek medical advice. Six students who suffered a needlestick injury began prophylactic human immunodeficiency virus medications. Of those students who suffered an injury, 15% had purchased disability insurance prior to the incident. CONCLUSIONS: Poor use of post-exposure procedures and a lack of disability insurance leave medical students at high risk for career and life-altering consequences from a needlestick injury

252.    Chen LH, Wilson ME. Nosocomial dengue by mucocutaneous transmission.[comment]. Emerging Infectious Diseases 2005; 11(5):775.
ABSTRACT: To the Editor: Wagner and colleagues report nosocomial dengue transmitted by needlestick and note that it is the fourth case of nosocomial dengue to their knowledge (1). In the same issue of Emerging Infectious Diseases, Nemes and colleagues report a separate case of nosocomial dengue also transmitted by needle-stick (2). Three other cases of nosocomial dengue transmission by needlestick have previously been published (3-5).

253.    Dix K. Best Practices for Purchasing Managers. Infection Control Today 2005; 9(7):34-38.
ABSTRACT: Purchasing managers for the healthcare community face a unique challenge--obtaining the best vales possible for the healthcare facility while ensuring that patient safety and infection control issues are kept at the forefront.

254.    edo de OA, White KL, Leschinsky DP et al. An outbreak of hepatitis C virus infections among outpatients at a hematology/oncology clinic.[see comment][summary for patients in Ann Intern Med. 2005 Jun 7;142(11):I38; PMID: 15941692]. Annals of Internal Medicine 2005; 142(11):898-902.
ABSTRACT: BACKGROUND: Approximately 2.7 million persons in the United States have chronic hepatitis C virus (HCV) infection. Health care-associated HCV transmission can occur if aseptic technique is not followed. The authors suspected a health care-associated HCV outbreak after the report of 4 HCV infections among patients at the same hematology/oncology clinic. OBJECTIVE: To determine the extent and mechanism of HCV transmission among clinic patients. DESIGN: Epidemiologic analysis through a cohort study. SETTING: Hematology/oncology clinic in eastern Nebraska. PARTICIPANTS: Patients who visited the clinic from March 2000 through December 2001. MEASUREMENTS: HCV infection status, relevant medical history, and clinic-associated exposures. Bivariate analysis and logistic regression were used to identify risk factors for HCV infection. RESULTS: Of 613 clinic patients contacted, 494 (81%) underwent HCV testing. The authors documented infection in 99 patients who lacked previous evidence of HCV infection; all had begun treatment at the clinic before July 2001. Hepatitis C virus genotype 3a was present in all 95 genotyped samples and presumably originated from a patient with chronic hepatitis C who began treatment in March 2000. Infection with HCV was statistically significantly associated with receipt of saline flushes (P < 0.001). Shared saline bags were probably contaminated when syringes used to draw blood from venous catheters were reused to withdraw saline solution. The clinic corrected this procedure in July 2001. LIMITATION: The delay between outbreak and investigation (>1 year) may have contributed to an underestimate of cases. CONCLUSIONS: This large health care-associated HCV outbreak was related to shared saline bags contaminated through syringe reuse. Effective infection-control programs are needed to ensure high standards of care in outpatient care facilities, such as hematology/oncology clinics

255.    Eikelboom JW. RE: Bain B.J. (2004) Bone marrow biopsy morbidity and mortality: 2002 data. Clinical and Laboratory Haematology 26, 315-318.[comment]. Clinical & Laboratory Haematology 2005; 27(3):209-210.
ABSTRACT: Sir, the report by  Bain (2004) documenting a 0.12% incidence of adverse events, including major bleeding, among more than 13k000 bone marrow biopsy procedures performed by members of the British Society of Haematology during 2002 is an important reminder for clinicians who perform t hese procedures: while complications are rare, they may be serious.

256.    Ellis K. Sharp Thinking: The Role of Technology and Education in Promoting Sharps Safety. Infection Control Today 2005; 9(7):20-24.
ABSTRACT: Infection control practitioners (ICPs) are intimately aware of the potential danger to healthcare workers (HCWs) posed by bloodborne pathogens via accidental needlestick accidental injuries.  While the exact prevalence of such injuries is unknown, the National Institute for Occupational Safety and Health (NIOSH) estimates put the number somewhere between 600,000 and 800,000 per year.  Furthermore, about half of these are not reported.  Other studies actively seeking to monitor the rate of needlestick injuries have reported as many as 839 injuries per 1,000 HCWs.  The cost that facilities must absorb to manage these injuries is significant, and can become catastrophic if the injury results in the acquisition of an infectious disease.

257.    Fry DE. Occupational blood-borne diseases in surgery. [Review] [25 refs]. American Journal of Surgery 2005; 190(2):249-254.
ABSTRACT: BACKGROUND: Human immunodeficiency virus (HIV), hepatitis B (HBV), and hepatitis C (HCV) infections are transmitted by blood exposure. Surgeons have been concerned about the risks of blood exposure in the operating room as a potential source of occupational infections from these viruses. The actual risk and frequency of operating room transmission remains poorly understood by many surgeons. METHODS: The pertinent recent literature on the pathophysiology, diagnosis, prevention, and treatment of HIV, HBV and HCV were reviewed to address the current understanding of these viruses as occupational risks to surgeons. RESULTS: HIV transmission to surgeons has not been documented in the United States by the Centers for Disease Control. HIV transmission from a surgeon to a patient in the environment of the operating room, as well as transmission from an HIV-infected surgeon to a patient, has not been documented. HBV infection of surgeons has declined with the general acceptance of the HBV vaccine. HCV infection remains a real risk for transmission in the operating room, given that no vaccine is currently available and that the overall number of chronically infected patients remains quite high. CONCLUSION: The risk of occupational infection from known viral pathogens for surgeons is low, but it is not zero. Effective barriers, modified patterns of behavior, and prompt responses to blood exposure events are the best methods for prevention. [References: 25]

258.    Gutierrez EB, Lopes MH, Yasuda MA. Accidental exposure to biological material in healthcare workers at a university hospital: Evaluation and follow-up of 404 cases. Scand J Infect Dis 2005; 37(4):295-300.
ABSTRACT: The care and follow-up provided to healthcare workers (HCWs) from a large teaching hospital who were exposed to biological material between 1 August 1998 and 31 January 2002 is described here. After exposure, the HCW is evaluated by a nurse and doctor in an emergency consultation and receives follow-up counselling. The collection of 10 ml of blood sample from each HCW and its source patient, when known, is made for immunoenzymatic testing for HIV, HBV and HCV. Evaluation and follow-up of 404 cases revealed that the exposures were concentrated in only a few areas of the hospital; 83% of the HCWs exposed were seen by a doctor responsible for the prophylaxis up to 3 h after exposure. Blood was involved in 76.7% (309) of the exposures. The patient source of the biological material was known in 80.7% (326) of the exposed individuals studied; 80 (24.5%) sources had serological evidence of infection with 1 or more agents: 16.2% were anti-HCV positive, 3.8% were HAgBs positive and 10.9% were anti-HIV positive. 67% (273) of the study population completed the proposed follow-up. No confirmed seroconversion occurred. In conclusion, the observed adherence to the follow-up was quite low, and measures to improve it must be taken. Surprisingly, no difference in adherence to the follow-up was observed among those exposed HCW at risk, i.e. those with an infected or unknown source patient. Analysis of post-exposure management revealed excess prescription of antiretroviral drugs, vaccine and immunoglobulin. Infection by HCV is the most important risk of concern, in our hospital, in accidents with biological material

259.    Health Protection Agency Centre for Infections, National Public Service for Wales, CDSC Northern Ireland. Eye of the Needle. Surveillance of Significant Occupational Exposure to Bloodborne Viruses in Healthcare Workers.  Seven-year report.  2005.
ABSTRACT: This report includes significant occupational exposure incidents reported to the HPA between 1st July 1996 and 30th June 2004 from reporting centres, currently 150, geographically scattered throughout England and four actively reporting centres in Wales and one actively reporting entre in Belfast in Northern Ireland.

260.    Hogan A. Gaps and successes of safety device market conversion. Materials Management in Health Care 2005; 14(11):33-34.
ABSTRACT:Technology and the engineering of safety devices has increased since the promulgation of the Bloodborne Pathogens Standard (BPS) (29 CFR 1910.1030) in 1991.
  As a result, OSHA revised its enforcement procedures in 1999 (CPL 02-02-069) to include guidance for its compliance safety and health officers to begin citing health care employers for failure to use safety devices where their use is feasible and effective.
  The Needlestick Safety and Prevention Act (NSPA), passed unanimously by Congress in 2000, further amplified the need for safety device adoption and use.

261.    Hopkins S. Safety and the 'Stick'. Advance/Laboratory 2005; 14(6):30-42.
ABSTRACT: In March 2000, the CDC estimated that more than 380,000 percutaneous injuries from contaminated sharps occur annually among healthcare workers in the United States.  Estimates also indicate that 600,000-800,000 work-related needlestick injuries occur annuall in the United States--about half of which go unreported.  And at an avaerage hospital, workers incur approximately 30 reported needlestick injuries per 100 beds per year.  Thus, it's extremely important that healthcare workers are aware of how these injuries occur, how to prevent them and what to do in case of injury.

262.    Iinuma Y, Igawa J, Takeshita M et al. Passive safety devices are more effective at reducing needlestick injuries. Journal of Hospital Infection 2005; 61(4):360-361.
ABSTRACT: Sir, Healthcare workers (HCWs) who use or who are exposed to needles are at risk of receiving needlestick injuries.  Such injuries can lead to serious infections with blood-borne pathogens such as human immunodeficiency virus, hepatitis B virus or hepatitis C virus. To reduce needlestick injuries, hospitals should replace their needles with needle-free safety technology (primary prevention). Where needles cannot be replaced, a safety engineered needle that covers the sharp after use should be used (secondary prevention).  There are two categories of safety engineered devices: user-activated safety devices and passive safety devices. A user-activated device requires HCWs to activate a safety mechanism and cover the sharp themselves, and a passive safety device features a design that automatically covers the sharp during use.

263.    Ismail NA, boul Ftouh AM, El Shoubary WH. Safe injection practice among health care workers, Gharbiya, Egypt. Journal of the Egyptian Public Health Association 2005; 80(5-6):563-583.
ABSTRACT: A cross-sectional study was conducted in 25 health care facilities in Gharbiya governorate to assess safe injection practices among health care workers (HCWs). Two questionnaires, one to collect information about administrative issues related to safe injection and the other to collect data about giving injections, exposure to needle stick injuries, hepatitis B vaccination status and safe injection training. Practices of injections were observed using a standardized checklist. The study revealed that there was lack of both national and local infection control policies and lack of most of the supplies needed for safe injection practices. Many safe practices were infrequent as proper needle manipulation before disposal (41%), safe needle disposal (47.5%), reuse of used syringe & needle (13.2%) and safe syringe disposal (0%). Exposure to needle stick injuries were common among the interviewed HCWs (66.2%) and hand washing was the common post exposure prophylaxis measure (63.4%). Only 11.3% of HCWs had full course hepatitis B vaccination. Infection control -including safe injections- training programs should be afforded to all HCWs

264.    Jahan S. Epidemiology of needlestick injuries among health care workers in a secondary care hospital in Saudi Arabia. Annals of Saudi Medicine 2005; 25(3):233-238.
ABSTRACT: BACKGROUND: Accidental needlestick injuries sustained by health care workers are a common occupational hazard in health care settings. The aim of this study was to review the epidemiology of needlestick injuries in Buraidah Central Hospital, a 212-bed secondary care hospital in Buraidah, Saudi Arabia. METHODS: We conducted a retrospective survey of all self-reported documents related to needlestick injuries, for the period January 2002 through December 2003. The data was analyzed to determine the age, sex and job category of the health care worker suffering the injury as well as the risk factors responsible for needlestick injuries. RESULTS: During the 2-year period, employees reported 73 injuries from needles and other sharp objects. Nurses were involved in 66% of instances, physicians in 19%, technicians in 10%, and nonclinical support staff in 5.5%. The majority (53.4%) of the injuries occurred after use and before disposal of the objects. Syringe needles were responsible for 63% of all injuries. Most injuries occurred during recapping of used needles (29%), during surgery (19%), and by collision with sharps (14%). Disposal-related (11%) causes as well as injuries by concealed sharps (5%) occurred while handling linens or trash containing improperly disposed needles. CONCLUSION: This data emphasizes the importance of increased awareness, training and education of health care workers for reporting and prevention of needlestick injuries

265.    Kermode M, Jolley D, Langkham B, Thomas MS, Crofts N. Occupational exposure to blood and risk of bloodborne virus infection among health care workers in rural north Indian health care settings. Am J Infect Control 2005; 33(1):34-41.
ABSTRACT: BACKGROUND: Approximately 3 million health care workers (HCWs) experience percutaneous exposure to bloodborne viruses (BBVs) each year. This results in an estimated 16,000 hepatitis C, 66,000 hepatitis B, and 200 to 5000 human immunodeficiency virus (HIV) infections annually. More than 90% of these infections are occurring in low-income countries, and most are preventable. Several studies report the risks of occupational BBV infection for HCWs in high-income countries where a range of preventive interventions have been implemented. In contrast, the situation for HCWs in low-income countries is not well documented, and their health and safety remains a neglected issue. OBJECTIVE: To describe the extent of occupational exposure to blood and the risk of BBV infection among a group of